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  1. Article ; Online: Surgical Interventions in Coronavirus Disease 2019 Pleural and Pulmonary Complications: A Case Series of the Tertiary Thoracic Surgery Center Experience.

    Mokhber Dezfuli, Mojtaba / Abbasi Dezfuli, Azizollah / Ghorbani, Fariba / Razaghi, Mahshad / Soleimani, Salman / Daneshmand, Moein / Sheikhy, Ali / Sheikhy, Kambiz

    Surgical infections

    2023  Volume 24, Issue 10, Page(s) 936–941

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Female ; Adult ; Middle Aged ; Male ; Empyema, Pleural/surgery ; Pneumothorax/surgery ; Pneumothorax/complications ; Thoracic Surgery ; COVID-19/complications ; Pleural Effusion/surgery ; Pleural Effusion/complications ; Lung ; Retrospective Studies
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1440120-4
    ISSN 1557-8674 ; 1096-2964
    ISSN (online) 1557-8674
    ISSN 1096-2964
    DOI 10.1089/sur.2023.167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5617: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Fatal Outcome of Ruptured Pulmonary Hydatid Cyst.

    Sheikhy, Kambiz / Abbasi Dezfuli, Azizollah / Pejhan, Saviz / Sadegh Beigee, Farahnaz

    Tanaffos

    2018  Volume 17, Issue 2, Page(s) 138–141

    Abstract: Most authors believe that the optimal treatment for pulmonary hydatid cyst is surgery. Albendazole has been used as a prophylactic measure for reducing recurrence rate but there are some controversies about this strategy. Some researchers have described ... ...

    Abstract Most authors believe that the optimal treatment for pulmonary hydatid cyst is surgery. Albendazole has been used as a prophylactic measure for reducing recurrence rate but there are some controversies about this strategy. Some researchers have described the increased risk of spontaneous rupture of cysts following albendazole treatment. In this case report, we present a case of spontaneous rupture of pulmonary hydatid cyst with fatal outcome that may be the adverse cause of albendazole.
    Language English
    Publishing date 2018-12-05
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2233372-1
    ISSN 1735-0344
    ISSN 1735-0344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ex Vivo Lung Perfusion: Establishment and Operationalization in Iran.

    Shafaghi, Shadi / Abbasi Dezfuli, Azizollah / Ansari Aval, Zahra / Sheikhy, Kambiz / Farzanegan, Behrooz / Mortaz, Esmaeil / Emami, Habib / Aigner, Clemens / Hosseini-Baharanchi, Fatemeh Sadat / Najafizadeh, Katayoun

    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

    2017  Volume 15, Issue 1, Page(s) 82–88

    Abstract: Objectives: Although the number of lung transplants is limited because of general shortage of organ donors, ex vivo lung perfusion is a novel method with 2 main benefits, including better evaluation of lung potential and recovery of injured lungs. The ... ...

    Abstract Objectives: Although the number of lung transplants is limited because of general shortage of organ donors, ex vivo lung perfusion is a novel method with 2 main benefits, including better evaluation of lung potential and recovery of injured lungs. The main aim of this study was to establish and operationalize ex vivo lung perfusion as the first experience in Iran.
    Materials and methods: This was a prospective operational research study on 5 cases, including 1 pig from Vienna Medical University and 4 patients from Masih Daneshvari Hospital. All organ donations from brain dead donors were evaluated according to lung transplant or ex vivo lung perfusion criteria from May 2013 to July 2015 in Tehran, Iran. If a donor did not have any sign of severe chest trauma or pneumonia but had poor oxygenation due to possible atelectasis or neurogenic pulmonary edema, their lungs were included for ex vivo lung perfusion.
    Results: A successful trend in the difference between the pulmonary arterial Po2 and the left atrial Po2 was observed, as well as an increasing pattern in other functional parameters, including dynamic lung compliance and a decreasing trend in pulmonary vascular resistance.
    Conclusions: These initial trials indicate that ex vivo lung perfusion can lead to remarkable progress in lung transplant in Iran. They also provide several important pieces of guidance for successful ex vivo lung perfusion, including the necessity of following standard lung retrieval procedures and monitoring temperature and pressure precisely. The development of novel methods can provide opportunities for further research studies on lungs of deceased donors and lead to undiscovered findings. By keeping this science up to date in Iran and developing such new and creative methods, we can reveal effective strategies to promote the quality of donor lungs to support patients on transplant wait lists.
    MeSH term(s) Animals ; Arterial Pressure ; Donor Selection ; Humans ; Lung/blood supply ; Lung/surgery ; Lung Transplantation/methods ; Models, Animal ; Organ Preservation/adverse effects ; Organ Preservation/methods ; Perfusion/adverse effects ; Program Evaluation ; Prospective Studies ; Pulmonary Circulation ; Respiration ; Respiratory Function Tests ; Sus scrofa ; Temperature ; Time Factors ; Tissue Donors/supply & distribution ; Tissue and Organ Harvesting/adverse effects ; Tissue and Organ Harvesting/methods ; Vascular Resistance
    Language English
    Publishing date 2017-02
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2396778-X
    ISSN 2146-8427 ; 1304-0855
    ISSN (online) 2146-8427
    ISSN 1304-0855
    DOI 10.6002/ect.2015.0354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Normothermic Ex Vivo Lung Perfusion in Brain-dead Donors Reduces Inflammatory Cytokines and Toll-like Receptor Expression.

    Shafaghi, Shadi / Mortaz, Esmaeil / Abbasi Dezfuli, Azizollah / Godarzi, Hoda / Sheikhy, Kambiz / Ansari Aval, Zahra / Farzanegan, Behrooz / Emami, Habib / Hosseini-Baharanchi, Fatemeh Sadat / Najafizadeh, Katayoun

    Iranian journal of allergy, asthma, and immunology

    2016  Volume 15, Issue 5, Page(s) 340–354

    Abstract: Inflammatory responses and innate immunologic reactions play an important role in the respiratory system. Ex vivo lung perfusion (EVLP) is considered a novel method in the evaluation and reconditioning of donor lungs prior to transplantation. However, ... ...

    Abstract Inflammatory responses and innate immunologic reactions play an important role in the respiratory system. Ex vivo lung perfusion (EVLP) is considered a novel method in the evaluation and reconditioning of donor lungs prior to transplantation. However, EVLP's effect on inflammatory and metabolic markers of human lung tissue is unknown.  This study investigated how the performance of EVLP on brain-dead (BD) donor lungs affects the production and release of inflammatory cytokines (IL-6, IL-8, and TNF-a), inflammatory cells and toll-like receptors (TLR) -2, 4. This study was conducted with an animal subject for qualification of EVLP team and then EVLP was performed on 4 human cases referred to Masih Daneshvari Hospital (Tehran,Iran), from May 2013 to July 2015. Two of these cases, who had acceptable lung function parameters, were enrolled in this study for immunologic investigations. Bronchoalveolar lavages (BAL) were taken before and after EVLP. Cytokines were quantitatively measured before lung retrieval, at the end of the lung removal, at the start of EVLP, and at the end of the each hour of EVLP. TLR expression was measured on the cells obtained by flow cytometry. TNF-a, IL-6 and IL-8 decreased in each stage of washing perfusate in both cases, and the level of cytokines in serum was in the normal range. Flow cytometry analysis revealed a decreasing expression of CD3, CD4/8, CD19, and CD16+56, as well as TLR-2 and TLR-4 in both cases. Intra-capillary pools of pro-inflammatory cytokines (IL-6, IL-8, and TNF-a) were determined to contribute to the lung injury during prolonged lung perfusion. This raises the possibility that EVLP donor lungs could be less immunogenic than standard lungs. However, to assess EVLP's effects on lung grafts and optimize recipient outcomes, further studies with a sufficient number of lungs are required.
    MeSH term(s) Brain Death ; Cytokines/immunology ; Female ; Gene Expression Regulation/immunology ; Humans ; Inflammation/immunology ; Lung/immunology ; Lung Transplantation ; Male ; Perfusion ; Tissue Donors ; Toll-Like Receptor 2/immunology ; Toll-Like Receptor 4/immunology
    Chemical Substances Cytokines ; TLR2 protein, human ; TLR4 protein, human ; Toll-Like Receptor 2 ; Toll-Like Receptor 4
    Language English
    Publishing date 2016-10
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2488724-9
    ISSN 1735-1502
    ISSN 1735-1502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6806: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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