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Article ; Online: One-time definitive attachment connection versus healing abutment placement for an implant-retained mandibular overdenture: Peri-implant metabolic activity.

Ibrahim, Abdallah Mohammed / Elgamal, Mohamed / Ragheb, Nourhan Ahmed

2024

Abstract: Statement of problem: Unscrewing the healing abutment can affect the soft tissue integration and apical migration of the biological width, which may compromise the integrity of peri-implant soft tissue.: Purpose: The purpose of this clinical study ... ...

Abstract	Statement of problem: Unscrewing the healing abutment can affect the soft tissue integration and apical migration of the biological width, which may compromise the integrity of peri-implant soft tissue. Purpose: The purpose of this clinical study was to determine the level of glycosaminoglycan (GAG) detected in the peri-implant crevicular fluid (PICF) between the test group (1-time abutment) and control group (healing abutment) for implant-retained mandibular overdentures. Material and methods: Two dental implants were installed in the canine regions of the mandibular ridge of 18 healthy completely edentulous participants using 2-stage surgery and a delayed loading protocol. At the second stage surgery, the implant on the right side was exposed, and a healing abutment was screwed onto the implant (control group), while on the left side the definitive ball abutment was screwed onto the implant (test group). After 10 days, the healing abutment in the control group was unscrewed and replaced with the definitive ball abutment. For both groups, the ball attachment was directly picked up to incorporate the attachment house to the mandibular denture. PICF samples were collected from the participants at 7 days, 3 months, and 6 months after overdenture use. Statistical analysis was done with an independent samples t test (α=.05). Results: A significant difference was found in the volume of PICF and the level of GAG between the test and control groups at the 7-day evaluation period (P=.008, P=.002, respectively), while the volumes of PICF and the levels of GAG were not significantly different (P>.05) at the other evaluation periods. Conclusions: The 1-time abutment protocol offers biochemical and economic advantages compared with the conventional method of using the healing abutment before placement of the definitive attachment for an implant-retained overdenture with single attachments.
Language	English
Publishing date	2024-04-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	218157-5
ISSN	1097-6841 ; 0022-3913
ISSN (online)	1097-6841
ISSN	0022-3913
DOI	10.1016/j.prosdent.2024.03.008
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Article ; Online: Strategies and sustainability in fast charging station deployment for electric vehicles

Abdallah Mohammed / Omar Saif / Maged Abo-Adma / Ashraf Fahmy / Rasha Elazab

Scientific Reports, Vol 14, Iss 1, Pp 1-

2024 Volume 19

Abstract: Abstract This comprehensive review investigates the growing adoption of electric vehicles (EVs) as a practical solution for environmental concerns associated with fossil fuel usage in mobility. The increasing demand for EVs underscores the critical ... ...

Abstract	Abstract This comprehensive review investigates the growing adoption of electric vehicles (EVs) as a practical solution for environmental concerns associated with fossil fuel usage in mobility. The increasing demand for EVs underscores the critical importance of establishing efficient, fast-charging infrastructure, especially from the standpoint of the electrical power grid. The review systematically examines the planning strategies and considerations for deploying electric vehicle fast charging stations. It emphasizes their unique dual role as loads and storage units, intricately linked to diverse road and user constraints. Furthermore, the review underscores the significant opportunity surrounding these stations for the integration of distributed renewable energy sources. It thoroughly explores the challenges and opportunities intrinsic to the planning and localization process, providing insights into the complexities associated with these multifaceted stations. Renewable resources, including wind and solar energy, are investigated for their potential in powering these charging stations, with a simultaneous exploration of energy storage systems to minimize environmental impact and boost sustainability. In addition to analyzing planning approaches, the review evaluates existing simulation models and optimization tools employed in designing and operating fast charging stations. The review consolidates key findings and offers recommendations to researchers and grid authorities, addressing critical research gaps arising from the escalating demand for electric vehicle fast-charging infrastructure. This synthesis is a valuable resource for advancing understanding and implementing robust strategies in integrating EVs with the electrical power grid.
Keywords	Medicine ; R ; Science ; Q
Subject code	620
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
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Article ; Online: Lost in translation: the pitfalls of Ensembl gene annotations between human genome assemblies and their impact on diagnostics.

Abdallah, Mohammed O E / Koko, Mahmoud / Ramesar, Raj

Expert review of molecular diagnostics

2023 Volume 23, Issue 8, Page(s) 723–727

Abstract: Background: Gene models based on GRCh37 human genome assembly are preferred by many international projects over other updated assemblies (GRCh38 and T2T). Discrepant genes (DGs), those recognized as protein coding in the new but not the old assembly, ... ...

Abstract	Background: Gene models based on GRCh37 human genome assembly are preferred by many international projects over other updated assemblies (GRCh38 and T2T). Discrepant genes (DGs), those recognized as protein coding in the new but not the old assembly, are ignored by several genomic resources and discarded by variant prioritization tools relying on information based on GRCh37. Methods: We curated a set of Ensembl genes with discrepant annotations between GRCh37 and GRCh38, additionally matching their RefSeq transcripts. Furthermore, we examined their clinical and phenotypic relevance. Results: A total of 337 genes were reclassified as 'protein-coding' in GRCh38 but not in GRCh37, with 194 having a discrepant HGNC gene symbol. Many remain missing from the current known RefSeq gene models ( Conclusion: For discrepant genes, the inaccurate label of 'non-protein-coding' has relevant ramifications on clinical genetics. Accurate collation of these genes allows for manual curation in clinically relevant scenarios.
MeSH term(s)	Humans ; Molecular Sequence Annotation ; Genome, Human ; Genomics
Language	English
Publishing date	2023-07-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2112530-2
ISSN	1744-8352 ; 1473-7159
ISSN (online)	1744-8352
ISSN	1473-7159
DOI	10.1080/14737159.2023.2237411
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Article: Endovascular retrieval of left atrial appendage closure device embolized to the aorta.

Horton, Crista E / Athas, Vincent / Ring, David / Abdallah, Mohammed

Journal of vascular surgery cases and innovative techniques

2023 Volume 9, Issue 3, Page(s) 101222

Abstract: Patients with atrial fibrillation with contraindications to anticoagulation can undergo left atrial appendage closure with a device. Hours after a 73-year-old man had undergone left atrial appendage closure, he lost perfusion to his lower extremities. ... ...

Abstract	Patients with atrial fibrillation with contraindications to anticoagulation can undergo left atrial appendage closure with a device. Hours after a 73-year-old man had undergone left atrial appendage closure, he lost perfusion to his lower extremities. Imaging studies showed that the device had migrated to the infrarenal aorta. After right common femoral artery cutdown and sheath placement, the device was retrieved with a balloon embolectomy catheter, and a balloon was simultaneously deployed in the proximal left common femoral artery to prevent device embolization. To the best of our knowledge, this report represents the first documented device retrieval from the aorta using balloon embolectomy and contralateral lower extremity embolic protection.
Language	English
Publishing date	2023-05-23
Publishing country	United States
Document type	Case Reports
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2023.101222
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Article ; Online: Cubosomal Betamethasone-Salicylic Acid Nano Drug Delivery System for Enhanced Management of Scalp Psoriasis.

Shalaby, Rodayna Atef / El-Gazayerly, Omaima / Abdallah, Mohammed

International journal of nanomedicine

2022 Volume 17, Page(s) 1659–1677

Abstract: Introduction: Betamethasone dipropionate (BD), a potent corticosteroid, and salicylic acid (SA), a keratolytic agent, have been used in combination to treat scalp psoriasis; however, undesirable side effects associated with their prolonged topical use ... ...

Abstract	Introduction: Betamethasone dipropionate (BD), a potent corticosteroid, and salicylic acid (SA), a keratolytic agent, have been used in combination to treat scalp psoriasis; however, undesirable side effects associated with their prolonged topical use are inevitable. In this study, BD and SA were loaded into cubosomes, a nanoparticulate system with outstanding biocompatibility, bio-adhesivity and penetration power. Methods: Design of experiments (DOE) was utilized to prepare thirteen different cubosomal dispersions by emulsification technique using glycerol monoolein (GMO) as a lipid phase and Poloxamer 407 (P407) as a surfactant, sodium carboxymethyl cellulose (SCMC) was added to enhance the dispersions' rheological properties. The thirteen dispersions were in-vitro characterized for their particle size, polydispersity index (PDI), zeta potential, BD and SA content and rheological behaviour. The desirability of an optimized formula (OF) was set to the smallest particle size, lowest zeta-potential and highest viscosity. The OF was in-vitro characterized for the same parameters in addition to transmission electron microscope imaging and in-vitro drug release. The OF's anti-psoriatic activity was evaluated in-vivo using an imiquimod-induced psoriasis model. Results: The OF achieved a particle size of 197.4 ± 9.47 nm, a PDI of 0.443 ± 0.025, a zeta potential of -44.4 ± 0.141mv, BD content of 105.85 ± 2.290%, SA content of 88.855 ± 2.920% with shear-thinning rheological behaviour and completed in-vitro drug release within 2-3 hours. The in-vivo studies confirmed the cubosomes' higher anti-psoriatic efficacy over the commercial product with lower changes in ear thickness, spleen to body weight ratio, psoriasis area severity index score and improved histopathological findings. Conclusion: The developed BD SA-loaded cubosomes exhibit promising anti-psoriatic activity attributed to its nano-size and unique lipid content, with enhanced skin penetration and modified rheological properties; increasing the formulation's in-contact duration with the scalp resulting in lower application frequency and thus reduced BD and SA associated side effects.
MeSH term(s)	Betamethasone/therapeutic use ; Gels ; Humans ; Nanoparticle Drug Delivery System ; Psoriasis/drug therapy ; Salicylic Acid/therapeutic use ; Scalp
Chemical Substances	Gels ; Nanoparticle Drug Delivery System ; Betamethasone (9842X06Q6M) ; Salicylic Acid (O414PZ4LPZ)
Language	English
Publishing date	2022-04-13
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2364941-0
ISSN	1178-2013 ; 1176-9114
ISSN (online)	1178-2013
ISSN	1176-9114
DOI	10.2147/IJN.S345430
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Article ; Online: Solusomes (novel soluplus

Abdallah, Mohammed / Mohamed, Aysha Sayed / Tadros, Mina Ibrahim / El-Nabarawi, Mohamed / Tawfik, Mai Ahmed

Pharmaceutical development and technology

2023 Volume 29, Issue 1, Page(s) 13–24

Abstract: Candesartan cilexetil (CAN) is administered for treating hypertension and heart failure. CAN suffers poor oral bioavailability, owing to limited aqueous solubility, and first-pass metabolism. Solusomes (novel ... ...

Abstract	Candesartan cilexetil (CAN) is administered for treating hypertension and heart failure. CAN suffers poor oral bioavailability, owing to limited aqueous solubility, and first-pass metabolism. Solusomes (novel Soluplus
MeSH term(s)	Animals ; Rabbits ; Biological Availability ; Polyethylene Glycols ; Solubility ; Administration, Oral ; Particle Size ; Benzimidazoles ; Biphenyl Compounds ; Polyvinyls ; Tetrazoles
Chemical Substances	polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer ; candesartan cilexetil (R85M2X0D68) ; Polyethylene Glycols (3WJQ0SDW1A) ; Benzimidazoles ; Biphenyl Compounds ; Polyvinyls ; Tetrazoles
Language	English
Publishing date	2023-12-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1331774-x
ISSN	1097-9867 ; 1083-7450
ISSN (online)	1097-9867
ISSN	1083-7450
DOI	10.1080/10837450.2023.2289166
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Article ; Online: Maxillary "All-on-six" treatment using zygomatic implants. Bone loss evaluation by cone beam computed tomography; Three years' follow-up.

Abouelhuda, Amira Mokhtar / Ibrahim, Abdallah Mohammed / Elkenawy, Mohammed Hassan / Hegazy, Salah Abd ElFattah

The International journal of prosthodontics

2023 , Page(s) 2–30

Abstract: Purpose: To evaluate radiographic changes around six implants (Two posterior zygomatic and four conventional implants) used with fixed detachable restorations in patients with severe maxillary posterior resorption with either Polyether ether ketone ( ... ...

Abstract	Purpose: To evaluate radiographic changes around six implants (Two posterior zygomatic and four conventional implants) used with fixed detachable restorations in patients with severe maxillary posterior resorption with either Polyether ether ketone (PEEK) or titanium frameworks. Materials and methods: Twelve maxillary edentulous patients were rehabilitated with six implants, including two posterior zygomatic and 4 conventionally placed implants for each patient following all-on-six distribution, and opposing mandibular all-on-four implant retained fixed detachable prostheses. A two-stage surgical unloaded healing protocol was performed. According to framework and teeth materials, there were two groups; Group I: CAD-CAM milled framework from modified BioHPP PEEK, bonded to polymethylmethacrylate crowns. Group II: screw-retained CAD-CAM milled framework from titanium, bonded to zirconium crowns. Bone loss evaluation for six implants was performed using cone beam computed tomography at the time of insertion (T0), after one year (T1), and after three years (T2). Results: There was a statistically significant difference in bone loss between PEEK and titanium groups. Less bone loss in PEEK groups around anterior conventional implants at buccal surfaces (P =0.01), at mesial surfaces (P <0.001), at distal surfaces (P <0.001), and zygomatic implants at buccal surfaces (P =0.004), and at palatal surfaces (P =0.003). Conclusions: Within the limitations of the study, the full-arch PEEK and titanium frameworks of fixed-detachable prostheses used with an All-on-Six distribution using zygomatic implants for rehabilitation of maxillary edentulous atrophied posterior arches was a promising treatment approach. Less bone loss was observed with the PEEK framework restorations combined with the PMMA crowns group.
Language	English
Publishing date	2023-09-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	645046-5
ISSN	1942-4426 ; 0893-2174
ISSN (online)	1942-4426
ISSN	0893-2174
DOI	10.11607/ijp.8744
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Article ; Online: Innovative approach for predicting daily reference evapotranspiration using improved shallow and deep learning models in a coastal region: A comparative study.

Elzain, Hussam Eldin / Abdalla, Osman A / Abdallah, Mohammed / Al-Maktoumi, Ali / Eltayeb, Mohamed / Abba, Sani I

Journal of environmental management

2024 Volume 354, Page(s) 120246

Abstract: Accurate and reliable estimation of Reference Evapotranspiration (ETo) is crucial for water resources management, hydrological processes, and agricultural production. The FAO-56 Penman-Monteith (FAO-56PM) approach is recommended as the standard model for ...

Abstract	Accurate and reliable estimation of Reference Evapotranspiration (ETo) is crucial for water resources management, hydrological processes, and agricultural production. The FAO-56 Penman-Monteith (FAO-56PM) approach is recommended as the standard model for ETo estimation; nevertheless, the absence of comprehensive meteorological variables at many global locations frequently restricts its implementation. This study compares shallow learning (SL) and deep learning (DL) models for estimating daily ETo against the FAO-56PM approach based on various statistic metrics and graphic tool over a coastal Red Sea region, Sudan. A novel approach of the SL model, the Catboost Regressor (CBR) and three DL models: 1D-Convolutional Neural Networks (1D-CNN), Long Short-Term Memory (LSTM), and Gated Recurrent Unit (GRU) were adopted and coupled with a semi-supervised pseudo-labeling (PL) technique. Six scenarios were developed regarding different input combinations of meteorological variables such as air temperature (Tmin, Tmax, and Tmean), wind speed (U2), relative humidity (RH), sunshine hours duration (SSH), net radiation (Rn), and saturation vapor pressure deficit (es-ea). The results showed that the PL technique reduced the systematic error of SL and DL models during training for all the scenarios. The input combination of Tmin, Tmax, Tmean, and RH reflected higher performance than other combinations for all employed models. The CBR-PL model demonstrated good generalization abilities to predict daily ETo and was the overall superior model in the testing phase according to prediction accuracy, stability analysis, and less computation cost compared to DL models. Thus, the relatively simple CBR-PL model is highly recommended as a promising tool for predicting daily ETo in coastal regions worldwide which have limited climate data.
MeSH term(s)	Deep Learning ; Neural Networks, Computer ; Climate ; Wind ; Temperature
Language	English
Publishing date	2024-02-14
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2024.120246
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Article ; Online: COVID-19 data based on wavelet coherence estimates for selected countries in the Eastern Mediterranean

Asaad Mohammed Ahmed Babker / Omer Ibrahim Abdallah Mohammed / Lyashenko, V.

2020

Abstract: The development of the COVID-19 pandemic makes it necessary to conduct various studies on this topic. One of the key questions is the study of the dynamics of the development of this disease. It is important to know for each country. At the same time, ... ...

Abstract	The development of the COVID-19 pandemic makes it necessary to conduct various studies on this topic. One of the key questions is the study of the dynamics of the development of this disease. It is important to know for each country. At the same time, the study of the dynamics of the development of COVID-19 for countries in a particular region is relevant. The main objective of this study is to analyze the main indicators of the development of the COVID-19 epidemic for individual countries in the eastern Mediterranean. Abbreviations if possible. We review statistics that characterize the total number of confirmed cases of COVID-19, total number of recovered, total number of deaths. This is cumulative data. These data are considered for each individual country from the selected region. Also summarized data for the selected region are considered. To analyze the data, we use estimates of the wavelet coherence values. We obtained estimates of wavelet coherence values for countries such as: Egypt, Israel, Jordan, Lebanon, Syria, Turkey and Cyprus. These estimates reflect the depth of the relationship between total number of confirmed cases of COVID-19 and total number of recovered, between total number of confirmed cases of COVID-19 and total number of deaths. This makes it possible to assess the degree of influence between the series of data that are being investigated. This allows us to draw conclusions about the development of the COVID-19 pandemic. The results are obtained that explain some aspects of the dynamics of the COVID-19 pandemic in individual countries of the selected region.
Keywords	Viruses ; COVID-19 ; Wavelet analysis ; Wavelet coherence ; covid19
Language	English
Publisher	WJARR
Publishing country	ua
Document type	Article ; Online
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Article ; Online: COVID-19 wavelet coherence data for some Gulf countries

Lyashenko, V. / Omer Ibrahim Abdallah Mohammed / Asaad Mohammed Ahmed Babker

2020

Abstract: Coronaviruses are one of the most dangerous forms of viruses. The development of the COVID-19 pandemic takes the form of a potential threat to all of humanity. This is due to the fact that coronaviruses have high pathogenicity, the ability to overcome ... ...

Abstract	Coronaviruses are one of the most dangerous forms of viruses. The development of the COVID-19 pandemic takes the form of a potential threat to all of humanity. This is due to the fact that coronaviruses have high pathogenicity, the ability to overcome human immunity. There are also difficulties in treating diseases that are associated with coronavirus. To solve such issues, it is important to obtain reliable statistical data, as well as conduct a comprehensive analysis of the data that are currently received. Based on this, the paper considers the possibility of analyzing data on the development of the COVID-19 pandemic based on wavelet analysis approaches. The wavelet coherence method was used as the main approach for statistical data analysis. The consistency of the results for different countries of the Persian Gulf is shown. Based on the analysis of the depth of cross-references between the studied data series, the most significant time periods were obtained until patients recover or die. Some explanation is given for the patterns that arise for individual Gulf countries. The data obtained can be used in the fight against the pandemic COVID-19, understanding the dynamics of its development.
Keywords	Viruses ; COVID-19 ; covid19
Language	English
Publisher	GSC
Publishing country	ua
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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