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  1. Article: Autologous Nanofat Injection Combined with Fractional CO2 Laser in the Treatment of Atrophic Acne Scars.

    Rageh, Mahmoud A / Ibrahim, Shady Mahmoud Attia / Abdallah, Noha / Tawfik, Abeer Attia

    Clinical, cosmetic and investigational dermatology

    2024  Volume 17, Page(s) 697–705

    Abstract: Background: Atrophic acne scarring is a widely prevalent condition and one of the most distressing complications of acne vulgaris. Numerous options with variable outcomes are available for the treatment of acne scarring. Laser is considered a first-line ...

    Abstract Background: Atrophic acne scarring is a widely prevalent condition and one of the most distressing complications of acne vulgaris. Numerous options with variable outcomes are available for the treatment of acne scarring. Laser is considered a first-line therapy for acne scars, and recently there has been a growing interest in using stem cells and their derivatives for treating acne scars. In addition, combined therapeutic modalities often achieve more satisfactory results than a single treatment.
    Objective: We tried to evaluate the role of nanofat and fractional CO2 laser as a combined treatment approach for atrophic acne scarring.
    Methods: Twenty-five patients with atrophic acne scarring were enrolled. They received a single session of intradermal nanofat injection, at different points 1 cm apart, for acne scars. Two weeks later, they were treated with three sessions of fractional CO2 laser at monthly intervals. Patients were evaluated three months after the last session using the quantitative Goodman and Baron scoring system. Pain, side effects, and patients' satisfaction were also evaluated.
    Results: There were two males and 23 females with a mean age of 25.96 years. Their skin type ranged between Fitzpatrick skin type III, IV, and V. Boxcar scars were the most common scar type in 13 patients (52%). After treatment, there was a significant reduction (p <0.05) in the quantitative Goodman and Baron scores. The improvement was more evident in rolling scars. Seven patients reported significant improvement, and 12 reported marked improvement.
    Conclusion: This study showed that combining nanofat and fractional CO2 laser is a safe and effective treatment modality for atrophic acne scars.
    Language English
    Publishing date 2024-03-20
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S454514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Fractional CO 2 Laser Combined With Autologous Nanofat Injection Versus Fractional CO 2 Laser Combined With Platelet-Rich Plasma in the Treatment of Atrophic Acne Scars: A Split-Face Comparative Study With Optical Skin Imaging.

    Rageh, Mahmoud A / Tawfik, Abeer Attia / Abdallah, Noha / Ibrahim, Shady Mahmoud Attia

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2023  Volume 50, Issue 1, Page(s) 75–80

    Abstract: Background: Atrophic acne scarring is a common problem. If left untreated, its implications can impair the quality of life. Various treatments, with differing degrees of success, are used to alleviate atrophic scars.: Objective: To assess the ... ...

    Abstract Background: Atrophic acne scarring is a common problem. If left untreated, its implications can impair the quality of life. Various treatments, with differing degrees of success, are used to alleviate atrophic scars.
    Objective: To assess the efficacy of nanofat versus platelet-rich plasma (PRP) as an adjuvant therapy to fractional CO 2 laser (FCL) for atrophic acne scars.
    Methods: This study included 35 patients with atrophic acne scars who received 3 sessions of FCL at 1-month intervals on both sides of the face, followed by intradermal PRP injection on the left side. A single session of nanofat was injected into the right side of the face 2 weeks before the laser sessions. The evaluation was conducted 3 months after the final treatment session.
    Results: After treatment, the right side of the face showed a significant reduction in Goodman scores and the indentation index of the Antera camera. The left side showed a significant difference in Goodman scores, yet the Antera camera showed a nonsignificant improvement. Nonetheless, the difference between the 2 sides was statistically insignificant.
    Conclusion: Atrophic acne scars improved with both modalities. As a result, cotreatment with these techniques may synergistically affect atrophic acne scars in efficacy and safety.
    MeSH term(s) Humans ; Cicatrix/etiology ; Cicatrix/therapy ; Cicatrix/pathology ; Quality of Life ; Treatment Outcome ; Acne Vulgaris/complications ; Acne Vulgaris/therapy ; Connective Tissue Diseases ; Platelet-Rich Plasma ; Atrophy
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000003968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1212: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Platelet-rich plasma versus combined fractional carbon dioxide laser with platelet-rich plasma in the treatment of vitiligo: a comparative study.

    Kadry, Mostafa / Tawfik, Abeer / Abdallah, Noha / Badawi, Ashraf / Shokeir, Hisham

    Clinical, cosmetic and investigational dermatology

    2018  Volume 11, Page(s) 551–559

    Abstract: Purpose: The aim of this study was to assess the efficacy of platelet-rich plasma (PRP) vs combined fractional CO: Patients and methods: This prospective, randomized, intrapatient, comparative controlled study was conducted between June 2014 and June ...

    Abstract Purpose: The aim of this study was to assess the efficacy of platelet-rich plasma (PRP) vs combined fractional CO
    Patients and methods: This prospective, randomized, intrapatient, comparative controlled study was conducted between June 2014 and June 2016 at National Institute of Laser Enhanced Sciences (NILES), Cairo University, Cairo, Egypt. Thirty NSV patients were treated with PRP, Fr: CO
    Results: A highly significant reduction was demonstrated through vitiligo analysis by computer-assisted grid (VACAG) in the combined Fr: CO
    Conclusion: According to our study, combined Fr: CO
    Language English
    Publishing date 2018-11-08
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S178817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A split face comparative study between intradermal tranexamic acid and Erbium-YAG laser in treatment of melasma.

    Otb, Sarah / Shaarawy, Eman / Sadek, Ahmad / Abdallah, Noha / Agamia, Naglaa / Soliman, Mona / Tawfik, Abeer Attia

    The Journal of dermatological treatment

    2021  Volume 33, Issue 1, Page(s) 555–559

    Abstract: Background: Although there are different treatment modalities of melasma, it remains a challenging problem. Erbium-YAG laser proved its efficacy in melasma improvement with minimal downtime. Tranexamic acid (TA) is a new promising treatment of melasma.!# ...

    Abstract Background: Although there are different treatment modalities of melasma, it remains a challenging problem. Erbium-YAG laser proved its efficacy in melasma improvement with minimal downtime. Tranexamic acid (TA) is a new promising treatment of melasma.
    Objective: The first objective is to compare between the efficacy of intradermal injection of TA and Erbium-YAG laser in the treatment of melasma. The second objective is to use the dermoscope as an objective evaluation method.
    Patients and methods: A split face study was conducted on 28 patients. One side of the face received intradermal TA injection. The other side was treated with laser. Melasma Area and Severity Index (MASI) and the dermoscope were used for evaluation of treatment.
    Results: The MASI scores showed a significant decrease in TA treated side. The dermoscope assessment showed no significant difference in both treatment modalities.
    Conclusion: A promising results were obtained by both intradermal TA and Erbium:YAG laser; however, the TA yields a higher patient satisfaction because of its high efficiency and low cost.
    MeSH term(s) Erbium ; Humans ; Lasers, Solid-State/therapeutic use ; Melanosis/drug therapy ; Tranexamic Acid/therapeutic use ; Treatment Outcome
    Chemical Substances Tranexamic Acid (6T84R30KC1) ; Erbium (77B218D3YE)
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1036299-x
    ISSN 1471-1753 ; 0954-6634
    ISSN (online) 1471-1753
    ISSN 0954-6634
    DOI 10.1080/09546634.2020.1771259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2627: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Topical 5 fluorouracil cream vs combined 5 fluorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars.

    Tawfik, Abeer Attia / Fathy, Maha / Badawi, Ashraf / Abdallah, Noha / Shokeir, Hisham

    Clinical, cosmetic and investigational dermatology

    2019  Volume 12, Page(s) 173–180

    Abstract: Background: Topical 5 fluorouracil (5-FU) has been reported as one of the standard treatments for hypertrophic scars (HTS). Ablative fractional laser was found to have promising results in the delivery of topical drugs into the skin by creating vertical ...

    Abstract Background: Topical 5 fluorouracil (5-FU) has been reported as one of the standard treatments for hypertrophic scars (HTS). Ablative fractional laser was found to have promising results in the delivery of topical drugs into the skin by creating vertical channels through which the drugs can penetrate the skin. So far there have been no comparative studies performed to compare both modalities in the same patient and same anatomical region, especially in severe HTS.
    Objective: The aim of this study was to compare the effectiveness of topical 5-FU and combined topical 5-FU and laser in treating severe HTS.
    Patients and methods: Twenty-four severe HTS lesions were treated by 5-FU monotherapy and 5-FU combined with ablative fractional erbium YAG laser. Each lesion was divided into two parts. One part was treated with topical 5-FU twice weekly for 8 months. The other part was treated with combined topical 5-FU and ablative fractional erbium YAG laser once per month for 8 months. The scars' improvement was evaluated by Vancouver scar scale (VSS) and skin analysis camera.
    Results: The assessment by VSS showed a significant reduction in the mean height, pliability, and vascularity of the lesions which were treated with combined approaches compared to 5-FU monotherapy. Pain and ulceration occurred at a higher rate in the combination therapy group.
    Conclusion: Treatment of severe HTS with combined 5-FU and ablative fractional erbium YAG laser is more effective than 5-FU alone.
    Language English
    Publishing date 2019-03-14
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S191137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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