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  1. AU="Abdul Karim, Mustafa"
  2. AU="Bose, Chirantan"
  3. AU="Bell, J. F."
  4. AU="Creavin, Samuel T"
  5. AU="Boonprasong, Sakarin"
  6. AU="Sara Carvalho"
  7. AU="Xia, Zhenqing"

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  1. Article: Network analysis of anxiety and depressive symptoms among quarantined individuals: cross-sectional study.

    Abdul Karim, Mustafa / Ouanes, Sami / Reagu, Shuja M / Alabdulla, Majid

    BJPsych open

    2021  Volume 7, Issue 6, Page(s) e222

    Abstract: Background: The mental health burden of COVID-19 has been examined in different settings. Existing research has relied on the latent variable model in assessing COVID-19-related distress. Network theory provides an alternative framework wherein symptoms ...

    Abstract Background: The mental health burden of COVID-19 has been examined in different settings. Existing research has relied on the latent variable model in assessing COVID-19-related distress. Network theory provides an alternative framework wherein symptoms are conceptualised as causal, interconnected constituents rather than outcomes of mental disorders.
    Aims: To assess networks of self-reported anxiety and depressive symptoms among quarantined individuals.
    Method: Consenting individuals in different quarantine centres in Qatar completed the Patient Health Questionnaire Anxiety and Depression Scale. We used partial correlation network methods to illustrate interactions of self-reported psychopathology.
    Results: Participants with COVID-19 were significantly older and had a significantly higher proportion of males. The most central node was COVID-19, followed by thoughts of self-harm. COVID-19 status was strongly positively connected to thoughts of self-harm, which was positively connected to psychomotor changes, which were connected to decreased concentration. COVID-19 status was also positively connected to feeling anxious, which was strongly connected to inability to concentrate, which was connected to feeling afraid.
    Conclusions: COVID-19 was the most influential factor, with the highest number and strength of connections to psychopathology in a network of anxiety and depressive symptoms in a quarantine setting. Beyond the resolution of the infection, therapeutic interventions targeting psychomotor changes might prove beneficial in reducing suicidality among quarantined individuals with COVID-19. Follow-up with mental health services after COVID-19 infection is needed to restore psychological well-being. Further research is needed to understand the short- and long-term psychological effects of COVID-19, and the outcomes of different therapeutic interventions.
    Language English
    Publishing date 2021-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2829557-2
    ISSN 2056-4724
    ISSN 2056-4724
    DOI 10.1192/bjo.2021.1060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Suspected Agomelatine-induced restless legs syndrome: a case report.

    Abdul Karim, Mustafa / Al-Baz, Nadeen / Ouanes, Sami / Alabdulla, Majid / Haddad, Peter M

    BMC psychiatry

    2021  Volume 21, Issue 1, Page(s) 180

    Abstract: Background: Restless Legs Syndrome (RLS) is a sensorimotor disorder characterized by unpleasant and distressing sensations in the lower limbs that are more pronounced in the evening, commence or worsen at rest, and show partial or complete relief ... ...

    Abstract Background: Restless Legs Syndrome (RLS) is a sensorimotor disorder characterized by unpleasant and distressing sensations in the lower limbs that are more pronounced in the evening, commence or worsen at rest, and show partial or complete relief following movement. It can occur as a primary disorder, secondary to medical conditions or treatment with medications including but not limited to antidepressants or antipsychotics.
    Case presentation: A 32-year old man with major depressive disorder showed partial response to Escitalopram 10 mg daily. Agomelatine 25 mg at night was added to Escitalopram to treat his residual depressive symptoms, namely insomnia and tiredness. Within two days he developed restlessness and unpleasant sensations in his legs which were worse at night. Symptom severity increased over the following days, prompting an urgent consultation a week later. The patient's presentation met the criteria for RLS. Agomelatine was discontinued leaving the patient on Escitalopram alone. The patient's symptoms improved within 24 h of stopping Agomelatine, with complete resolution four days later. There was no recurrence of RLS during follow-up. The patient scored 6 on Naranjo's adverse drug reaction probability scale, indicating a probable adverse drug reaction caused by Agomelatine.
    Conclusions: To the best of our knowledge, this is the first case report of suspected Agomelatine-induced RLS. Clinicians need to be aware of RLS to enable prompt diagnosis and management. We suggest adding Agomelatine to the list of agents that can potentially induce RLS.
    MeSH term(s) Acetamides/adverse effects ; Adult ; Citalopram/adverse effects ; Depressive Disorder, Major/drug therapy ; Humans ; Male ; Restless Legs Syndrome/chemically induced ; Restless Legs Syndrome/diagnosis ; Restless Legs Syndrome/drug therapy
    Chemical Substances Acetamides ; Citalopram (0DHU5B8D6V) ; agomelatine (137R1N49AD)
    Language English
    Publishing date 2021-04-07
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-021-03175-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Newspaper depiction of mental and physical health in Qatar.

    Elzamzamy, Khalid / Alsiddiqi, Abdulkarim / Khalil, Ali / Elamin, Hassan / Abdul Karim, Mustafa / Wadoo, Ovais

    BJPsych international

    2021  Volume 18, Issue 1, Page(s) 12–15

    Abstract: This study provides an overview of the extent, nature and quality of reporting on mental health compared with physical health in Qatari newspapers. We analysed 1274 news reports from daily newspapers in Qatar. The majority of the articles provided ... ...

    Abstract This study provides an overview of the extent, nature and quality of reporting on mental health compared with physical health in Qatari newspapers. We analysed 1274 news reports from daily newspapers in Qatar. The majority of the articles provided general information and were either positive or neutral in tone, reporting purely on physical health matters. A small proportion made associations with violence or reported on suicide or substance use. Our results highlight the underrepresentation of mental health in Qatari newspapers. A collaboration between media and health professionals is recommended to improve reporting on mental health.
    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2905058-3
    ISSN 2058-6264 ; 2056-4740
    ISSN (online) 2058-6264
    ISSN 2056-4740
    DOI 10.1192/bji.2020.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prevalence and correlates of COVID-19 vaccine hesitancy among the elderly in Qatar: A cross-sectional study.

    Abdul Karim, Mustafa / Reagu, Shuja M / Ouanes, Sami / Waheed Khan, Abdul / Smidi, Wesam S / Al-Baz, Nadeen / Alabdulla, Majid

    Medicine

    2022  Volume 101, Issue 26, Page(s) e29741

    Abstract: Older individuals are more vulnerable to severe coronavirus disease 2019 and medical complications. Vaccination stands as an efficient and safe vanguard against infection. However, negative attitudes and perceptions pertaining to available vaccines might ...

    Abstract Older individuals are more vulnerable to severe coronavirus disease 2019 and medical complications. Vaccination stands as an efficient and safe vanguard against infection. However, negative attitudes and perceptions pertaining to available vaccines might hinder community inoculation. The aim of this study was to assess vaccine hesitancy and its psychosocial determinants among the elderly in Qatar. We conducted a cross-sectional study between October 15 and November 15, 2020, using a composite online survey including the Vaccine Attitudes Examination Scale in addition to questions on sociodemographic correlates and the role of healthcare professionals. The vaccine hesitancy rate was 19.5%. The main reasons for willingness to vaccinate included understanding the nature of disease and role of vaccination, in addition to information provided by physicians. Fears mainly centered around vaccine safety. Vaccine hesitators were more likely to be non-Qatari and having received the influenza vaccine at least once. Gender, marital status, socioeconomic status, educational level, and having completed childhood vaccinations were not associated with vaccine hesitancy. Efforts should be directed toward raising awareness of vaccine efficacy and safety profiles. Physicians should additionally be educated about their pivotal role in advocating vaccine acceptance. We recommend reassessing vaccine hesitancy and its associated factors following a year of campaigning and vaccine administration to identify and target vulnerable groups.
    MeSH term(s) Aged ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Humans ; Influenza Vaccines ; Parents/psychology ; Prevalence ; Urogenital Abnormalities ; Vaccination Hesitancy
    Chemical Substances COVID-19 Vaccines ; Influenza Vaccines
    Language English
    Publishing date 2022-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000029741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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