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  1. Article: Molecular docking, dynamics and

    Golchha, Nikita Chordia / Abdulhameed Odhar, Hasanain / Nighojkar, Anand / Nighojkar, Sadhana

    Bioinformation

    2024  Volume 20, Issue 1, Page(s) 39–48

    Abstract: The opportunistic pathogen, ...

    Abstract The opportunistic pathogen,
    Language English
    Publishing date 2024-01-31
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/973206300200039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Molecular docking analysis and dynamics simulation of salbutamol with the monoamine oxidase B (MAO-B) enzyme.

    Abdulhameed Odhar, Hasanain / Fadhil Hashim, Ahmed / Sami Humad, Suhad

    Bioinformation

    2022  Volume 18, Issue 3, Page(s) 304–309

    Abstract: The monoamine oxidase B (MAO-B) enzyme is linked with Parkinson's disease. Therefore, it is of interest to document the molecular docking analysis and dynamics simulation of salbutamol, a well-known β2-adrenoceptor agonist, with the monoamine oxidase B ( ... ...

    Abstract The monoamine oxidase B (MAO-B) enzyme is linked with Parkinson's disease. Therefore, it is of interest to document the molecular docking analysis and dynamics simulation of salbutamol, a well-known β2-adrenoceptor agonist, with the monoamine oxidase B (MAO-B) enzyme for further consideration in drug design and development.
    Language English
    Publishing date 2022-03-31
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630018304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Design and construction of multi epitope- peptide vaccine candidate for rabies virus.

    Abdulhameed Odhar, Hasanain / Hashim, Ahmed Fadhil / Humadi, Suhad Sami / Ahjel, Salam Waheed

    Bioinformation

    2023  Volume 19, Issue 2, Page(s) 167–177

    Abstract: Rabies virus is a zoonotic pathogen that causes lethal encephalitis with a case fatality rate of almost 100% in unvaccinated individuals. The currently available vaccines against rabies are composed of inactivated viral particles that only confer a short- ...

    Abstract Rabies virus is a zoonotic pathogen that causes lethal encephalitis with a case fatality rate of almost 100% in unvaccinated individuals. The currently available vaccines against rabies are composed of inactivated viral particles that only confer a short-term immune response. It is well-known that the entry of rabies virus into host cells is mediated by a trimeric glycoprotein presents on the surface of viral envelope. As the sole viral surface protein, this trimeric glycoprotein represents a promising molecular target to design new vaccines and neutralizing antibodies against rabies virus. Epitope mapping studies had identified several antigenic sites on the surface of trimeric pre-fusion glycoprotein of rabies virus. Therefore, it is of interest to screen the rabies virus glycoprotein by different web-based immuno-informatics tools to identify potential B-cells and T-cells linear epitopes. Here, we present a construct of peptide vaccine that consists of these predicted linear epitopes of rabies virus glycoprotein together with appropriate linkers and adjuvant. Various online prediction tools, molecular docking and dynamics simulation assume that the vaccine construct may be stable, safe and effective. However, validation of these in-silico results is necessary both in vitro and in vivo setting.
    Language English
    Publishing date 2023-02-28
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/97320630019167
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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