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Article ; Online: Extraction of some essential amino acids using aqueous two-phase systems made by sugar-based deep eutectic solvents.

Söğütlü, İnci / Saeed, Shakir Mahmood / Adil, Mohaned / Yadav, Anupam / Abdulkareem Mahmood, Evan / Saadh, Mohamed J

RSC advances

2023  Volume 13, Issue 29, Page(s) 19674–19681

Abstract: Aqueous two-phase systems (ATPSs) have long been recognized as versatile and efficient tools for the extraction of biomolecules, including amino acids. Recent advancements in the field have introduced a novel approach by utilizing deep eutectic solvents ( ...

Abstract Aqueous two-phase systems (ATPSs) have long been recognized as versatile and efficient tools for the extraction of biomolecules, including amino acids. Recent advancements in the field have introduced a novel approach by utilizing deep eutectic solvents (DES) to form ATPs. This study aimed to determine the phase diagrams for an ATPS made of polyethylene glycol dimethyl ether 250 and two types of NADESs, namely choline chloride as a hydrogen bond acceptor (HBA), and either sucrose or fructose as a hydrogen bond donor (HBD) with a molar ratio of 1 : 2. The measured tie-line results revealed that the hydrogen bonds of NADES may not be entirely disrupted in aqueous solutions, and thus, these ATPSs act as ternary-like systems. Additionally, the binodal data were fitted using two semi-empirical equations, namely Merchuk and Zafarani-Moattar
Language English
Publishing date 2023-06-29
Publishing country England
Document type Journal Article
ISSN 2046-2069
ISSN (online) 2046-2069
DOI 10.1039/d3ra03092j
Database MEDical Literature Analysis and Retrieval System OnLINE

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