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  1. Book ; Online: The interplay of common noise and finite pulses on biological neurons

    Afifurrahman / Mohd, Mohd Hafiz / Abdullah, Farah Aini

    2024  

    Abstract: The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the interaction of many ...

    Abstract The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the interaction of many neurons. A typical incoming stimulus resembles a noise which in principle can be described as a random variable. In computational neuroscience, the noise has been extensively studied for different setups. In this study, we investigate the effect of noisy inputs in a minimal network of two identical leaky integrate-and-fire (LIF) neurons interacting with finite pulses. In particular, we consider a Gaussian white noise as a standard function for stochastic modelling of neurons, while taking into account the pulse width as an elementary component for the signal transmission. By exploring the role of noise and finite pulses, the two neurons show a synchronous spiking behaviour characterized by fluctuations in the interspike intervals. Above some critical values the synchronous regime collapses onto asynchronous dynamics. The abrupt change in such dynamics is accompanied by a hysteresis, i.e., the coexistence of synchronous and asynchronous firing behaviour.

    Comment: 11 pages, 8 figures
    Keywords Quantitative Biology - Neurons and Cognition
    Subject code 612
    Publishing date 2024-01-07
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Investigation of the dynamical structures of double-chain deoxyribonucleic acid model in biological sciences.

    Yousaf, Muhammad Zain / Abbas, Muhammad / Nazir, Tahir / Abdullah, Farah Aini / Birhanu, Asnake / Emadifar, Homan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6410

    Abstract: The present research investigates the double-chain deoxyribonucleic acid model, which is important for the transfer and retention of genetic material in biological domains. This model is composed of two lengthy uniformly elastic filaments, that stand in ... ...

    Abstract The present research investigates the double-chain deoxyribonucleic acid model, which is important for the transfer and retention of genetic material in biological domains. This model is composed of two lengthy uniformly elastic filaments, that stand in for a pair of polynucleotide chains of the deoxyribonucleic acid molecule joined by hydrogen bonds among the bottom combination, demonstrating the hydrogen bonds formed within the chain's base pairs. The modified extended Fan sub equation method effectively used to explain the exact travelling wave solutions for the double-chain deoxyribonucleic acid model. Compared to the earlier, now in use methods, the previously described modified extended Fan sub equation method provide more innovative, comprehensive solutions and are relatively straightforward to implement. This method transforms a non-linear partial differential equation into an ODE by using a travelling wave transformation. Additionally, the study yields both single and mixed non-degenerate Jacobi elliptic function type solutions. The complexiton, kink wave, dark or anti-bell, V, anti-Z and singular wave shapes soliton solutions are a few of the creative solutions that have been constructed utilizing modified extended Fan sub equation method that can offer details on the transversal and longitudinal moves inside the DNA helix by freely chosen parameters. Solitons propagate at a consistent rate and retain their original shape. They are widely used in nonlinear models and can be found everywhere in nature. To help in understanding the physical significance of the double-chain deoxyribonucleic acid model, several solutions are shown with graphics in the form of contour, 2D and 3D graphs using computer software Mathematica 13.2. All of the requisite constraint factors that are required for the completed solutions to exist appear to be met. Therefore, our method of strengthening symbolic computations offers a powerful and effective mathematical tool for resolving various moderate nonlinear wave problems. The findings demonstrate the system's potentially very rich precise wave forms with biological significance. The fundamentals of double-chain deoxyribonucleic acid model diffusion and processing are demonstrated by this work, which marks a substantial development in our knowledge of double-chain deoxyribonucleic acid model movements.
    MeSH term(s) Nonlinear Dynamics ; Base Pairing ; Biological Science Disciplines ; Hydrogen Bonding ; DNA/chemistry
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2024-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55786-z
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  3. Article: A model for HIV/AIDS pandemic with optimal control.

    Sule, Amiru / Abdullah, Farah Aini

    AIP conference proceedings

    2020  Volume 1660, Issue 1, Page(s) 50007

    Abstract: Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action ... ...

    Abstract Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability analysis is carried out. And the disease free equilibrium of the basic model was found to be locally asymptotically stable whenever the threshold parameter (RO) value is less than one, and unstable otherwise. The model is extended by introducing two optimal control strategies namely, CD4 counts and treatment for the infective using optimal control theory. Numerical simulation was carried out in order to illustrate the analytic results.
    Keywords covid19
    Language English
    Publishing date 2020-03-31
    Publishing country United States
    Document type Journal Article
    ISSN 0094-243X
    ISSN 0094-243X
    DOI 10.1063/1.4915640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: An efficient spline technique for solving time-fractional integro-differential equations.

    Abbas, Muhammad / Aslam, Sadia / Abdullah, Farah Aini / Riaz, Muhammad Bilal / Gepreel, Khaled A

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19307

    Abstract: Spline curves are very prominent in the mathematics due to their simple construction, accuracy of assessment and ability to approximate complicated structures into interactive curved designs. A spline is a smooth piece-wise polynomial function. The ... ...

    Abstract Spline curves are very prominent in the mathematics due to their simple construction, accuracy of assessment and ability to approximate complicated structures into interactive curved designs. A spline is a smooth piece-wise polynomial function. The primary goal of this study is to use extended cubic B-spline (ExCuBS) functions with a new second order derivative approximation to obtain the numerical solution of the weakly singular kernel (SK) non-linear fractional partial integro-differential equation (FPIDE). The spatial and temporal fractional derivatives are discretized by ExCuBS and the Caputo finite difference scheme, respectively. The present study found that it is stable and convergent. The validity of the current approach is examined on a few test problems, and the obtained outcomes are compared with those that have previously been reported in the literature.
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19307
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  5. Article: Optical soliton solutions of the coupled Radhakrishnan-Kundu-Lakshmanan equation by using the extended direct algebraic approach.

    Mahmood, Ayesha / Srivastava, Hari Mohan / Abbas, Muhammad / Abdullah, Farah Aini / Othman Mohammed, Pshtiwan / Baleanu, Dumitru / Chorfi, Nejmeddine

    Heliyon

    2023  Volume 9, Issue 10, Page(s) e20852

    Abstract: The analytical soliton solutions place a lot of value on birefringent fibres. The major goal of this study is to generate novel forms of soliton solutions for the Radhakrishnan-Kundu-Lakshmanan equation, which depicts unstable optical solitons that arise ...

    Abstract The analytical soliton solutions place a lot of value on birefringent fibres. The major goal of this study is to generate novel forms of soliton solutions for the Radhakrishnan-Kundu-Lakshmanan equation, which depicts unstable optical solitons that arise from optical propagations using birefringent fibres. The (presumably new) extended direct algebraic (EDA) technique is used here to extract a large number of solutions for RKLE. It gives soliton solutions up to thirty-seven, which essentially correspond to all soliton families. This method's ability to determine many sorts of solutions through a single process is one of its key advantages. Additionally, it is simple to infer that the technique employed in this study is really straightforward yet one of the quite effective approaches to solving nonlinear partial differential equations so, this novel extended direct algebraic (EDA) technique may be regarded as a comprehensive procedure. The resulting solutions are found to be hyperbolic, periodic, trigonometric, bright and dark, combined bright-dark, and W-shaped soliton, and these solutions are visually represented by means of 2D, 3D, and density plots. The present study can be extended to investigate several other nonlinear systems to understand the physical insights of the optical propagations through birefringent fibre.
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e20852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Generalized and improved (G'/G)-expansion method for (3+1)-dimensional modified KdV-Zakharov-Kuznetsev equation.

    Naher, Hasibun / Abdullah, Farah Aini / Akbar, M Ali

    PloS one

    2013  Volume 8, Issue 5, Page(s) e64618

    Abstract: The generalized and improved (G'/G)-expansion method is a powerful and advantageous mathematical tool for establishing abundant new traveling wave solutions of nonlinear partial differential equations. In this article, we investigate the higher ... ...

    Abstract The generalized and improved (G'/G)-expansion method is a powerful and advantageous mathematical tool for establishing abundant new traveling wave solutions of nonlinear partial differential equations. In this article, we investigate the higher dimensional nonlinear evolution equation, namely, the (3+1)-dimensional modified KdV-Zakharov-Kuznetsev equation via this powerful method. The solutions are found in hyperbolic, trigonometric and rational function form involving more parameters and some of our constructed solutions are identical with results obtained by other authors if certain parameters take special values and some are new. The numerical results described in the figures were obtained with the aid of commercial software Maple.
    MeSH term(s) Algorithms ; Computer Graphics ; Computer Simulation ; Nonlinear Dynamics ; Software
    Language English
    Publishing date 2013-05-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0064618
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  7. Article: Some new traveling wave solutions of the modified Benjamin-Bona-Mahony equation via the improved (G/G)-expansion method

    Naher, Hasibun / Abdullah, Farah Aini / Bekir, Ahmet

    New Trends in Mathematical Sciences; Volume: 3 Issue: 1; 78-89

    Abstract: The improved (G’/G)-expansion method is a powerful mathematical tool for solving nonlinear evolution equations whicharise in mathematical physics, engineering sciences and other technical arena. In this article, we construct some new exact travelingwave ... ...

    Abstract The improved (G’/G)-expansion method is a powerful mathematical tool for solving nonlinear evolution equations whicharise in mathematical physics, engineering sciences and other technical arena. In this article, we construct some new exact travelingwave solutions for the modified Benjamin-Bona-Mahony equation by applying the improved (G’/G)-expansion method. In themethod, the general solution of the second order linear ordinary differential equation with constant coefficients is used for studyingnonlinear partial differential equations. The solution procedure of this method is executed by algebraic software, such as, Maple. Theobtained solutions including solitary and periodic wave solutions are presented in terms of the hyperbolic function, the trigonometricfunction and the rational forms. It is noteworthy to reveal that some of our solutions are in good agreement with the published resultsfor special cases which certifies our other solutions. Furthermore, the graphical presentations of some solutions are illustrated in thefigures
    Language English
    Document type Article
    ISSN 2147-5520
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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