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Article ; Online: Histamine H3 receptor antagonists - Roles in neurological and endocrine diseases and diabetes mellitus.

Abdulrazzaq, Yousef M / Bastaki, Salim M A / Adeghate, Ernest

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2022 Volume 150, Page(s) 112947

Abstract: Human histamine H3 receptor (H3R) was initially described in the brain of rat in 1983 and cloned in 1999. It can be found in the human brain and functions as a regulator of histamine synthesis and release. H3 receptors are predominantly resident in the ... ...

Abstract	Human histamine H3 receptor (H3R) was initially described in the brain of rat in 1983 and cloned in 1999. It can be found in the human brain and functions as a regulator of histamine synthesis and release. H3 receptors are predominantly resident in the presynaptic region of neurons containing histamine, where they modulate the synthesis and release of histamine (autoreceptor) or other neurotransmitters such as dopamine, norepinephrine, gamma-aminobutyric acid (GABA), glutamate, acetylcholine and serotonin (all heteroreceptors). The human histamine H3 receptor has twenty isoforms of which eight are functional. H3 receptor expression is seen in the cerebral cortex, neurons of the basal ganglia and hippocampus, which are important for process of cognition, sleep and homoeostatic regulation. In addition, histamine H3R antagonists stimulate insulin release, through inducing the release of acetylcholine and cause significant reduction in total body weight and triglycerides in obese subjects by causing a feeling of satiety in the hypothalamus. The ability of histamine H3R antagonist to reduce diabetes-induced hyperglycaemia is comparable to that of metformin. It is reasonable therefore, to claim that H3 receptor antagonists may play an important role in the therapy of disorders of cognition, the ability to sleep, oxidative stress, inflammation and anomaly of glucose homoeostasis. A large number of H3R antagonists are being developed by pharmaceutical companies and university research centres. As examples of these new drugs, this review will discuss a number of drugs, including the first histamine H3R receptor antagonist produced.
MeSH term(s)	Acetylcholine ; Animals ; Diabetes Mellitus ; Histamine ; Histamine Antagonists/pharmacology ; Histamine H3 Antagonists/pharmacology ; Histamine H3 Antagonists/therapeutic use ; Humans ; Rats ; Receptors, Histamine H3/metabolism
Chemical Substances	Histamine Antagonists ; Histamine H3 Antagonists ; Receptors, Histamine H3 ; Histamine (820484N8I3) ; Acetylcholine (N9YNS0M02X)
Language	English
Publishing date	2022-04-19
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2022.112947
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Article: Meal and Snack Patterns of Infants and Toddlers in the United Arab Emirates: The UAE Feeding Infants and Toddlers Study

Abdulrazzaq, Yousef M. / Abdulla, Shahraban / Belhaj, Ghazala

Dubai Medical Journal

2019 Volume 2, Issue 1, Page(s) 1–6

Abstract: Aim: To describe meal and snack patterns and practices of infants and toddlers in the UAE. Method: A random sample of 1,000 infants and toddlers, aged 5 months to 2 years and attending Public Health clinics for immunization, was recruited. One face-to- ... ...

Institution	Department of Paediatrics, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates Department of Paediatrics, Latifa Hospital, Dubai, United Arab Emirates Department of Paediatrics, Al Ain Hospital, Al Ain, United Arab Emirates
Abstract	Aim: To describe meal and snack patterns and practices of infants and toddlers in the UAE. Method: A random sample of 1,000 infants and toddlers, aged 5 months to 2 years and attending Public Health clinics for immunization, was recruited. One face-to-face interview in which caregivers reported the feeding pattern of their infants and toddlers in the preceding 24-h period was conducted. For statistics, we used percentages (proportions) by age group (5–11.9 and 12–24 months). Result: The rate of breastfeeding decreased with age from 60% at 5 months to 37% at 12 months. At the age of 5–6 months, 90% of infants had been introduced to complementary foods. Juice was consumed by 7% of the infants before the American Academy of Pediatrics-recommended age of 6 months. At the age of 9–11 months, 90–100% of infants consumed cows’ milk on a daily basis. Moreover, French fries and/or sweetened beverages were consumed by 10% of infants and toddlers. Chicken was the most commonly fed meat (19.6% of infants and 57.2% of toddlers). Conclusion: The study results provide important evidence of improper feeding in some children and would help in providing guidance to parents and caregivers about the introduction of appropriate solid foods at an appropriate time.
Keywords	Toddlers ; Infants ; Feeding ; Snacks ; Breast milk ; Complementary feed
Language	English
Publishing date	2019-02-06
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Research Article ; This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
ISSN	2571-726X
ISSN (online)	2571-726X
DOI	10.1159/000496110
Database	Karger publisher's database

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Article ; Online: Lipocalin-2: Structure, function, distribution and role in metabolic disorders.

Jaberi, Saeeda Al / Cohen, Athena / D'Souza, Crystal / Abdulrazzaq, Yousef M / Ojha, Shreesh / Bastaki, Salim / Adeghate, Ernest A

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2021 Volume 142, Page(s) 112002

Abstract: Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein responsible for the transportation of small and hydrophobic molecules (steroid, free fatty ... ...

Abstract	Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein responsible for the transportation of small and hydrophobic molecules (steroid, free fatty acids, prostaglandins and hormones) to target organs after binding to megalin/glycoprotein and GP330 SLC22A17 or 24p3R LCN-2 receptors. LCN-2 has been used as a biomarker for acute and chronic renal injury. It is present in a large variety of cells including neutrophil, hepatocytes, lung, bone marrow, adipose tissue, macrophages, thymus, non-neoplastic breast duct, prostate, and renal cells. Different functions have been associated with LCN-2. These functions include antibacterial, anti-inflammatory, and protection against cell and tissue stress. Moreover, LCN-2 can increase the pool of matrix metalloproteinase 9 in human neutrophil granulocytes. Other reported functions of LCN-2 include its ability to destroy the extracellular matrix, which could enable cancer progression and spread of metastasis. Recent reports show that the tissue level of LCN-2 is increased in metabolic disorders such as obesity and type 2 diabetes, suggesting an association between LCN-2 and insulin sensitivity and glucose homeostasis. The precise role of LCN-2 in the modulation of insulin sensitivity, glucose and lipid metabolism is still unclear. This review explores the structure of LCN-2, tissue distribution, and its interaction with important metabolic pathways.
MeSH term(s)	Animals ; Diabetes Mellitus, Type 2/physiopathology ; Extracellular Matrix/metabolism ; Glucose/metabolism ; Humans ; Insulin Resistance ; Lipid Metabolism/physiology ; Lipocalin-2/chemistry ; Lipocalin-2/metabolism ; Metabolic Diseases/physiopathology ; Obesity/physiopathology
Chemical Substances	LCN2 protein, human ; Lipocalin-2 ; Glucose (IY9XDZ35W2)
Language	English
Publishing date	2021-08-27
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2021.112002
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Article ; Online: Anticonvulsant and reproductive toxicological studies of the imidazole-based histamine H3R antagonist

Bastaki, Salim M / Abdulrazzaq, Yousef M / Shafiullah, Mohamed / Więcek, Małgorzata / Kieć-Kononowicz, Katarzyna / Sadek, Bassem

Drug design, development and therapy

2018 Volume 12, Page(s) 179–194

Abstract: The imidazole-based H3R ... ...

Abstract	The imidazole-based H3R antagonist
MeSH term(s)	Abnormalities, Drug-Induced/pathology ; Animals ; Anticonvulsants/pharmacology ; Body Weight/drug effects ; Dose-Response Relationship, Drug ; Female ; Fetus/drug effects ; Histamine H3 Antagonists/pharmacology ; Histamine H3 Antagonists/toxicity ; Imidazoles/pharmacology ; Imidazoles/toxicity ; Male ; Methylhistamines/pharmacology ; Methylhistamines/toxicity ; Mice ; Organogenesis/drug effects ; Placenta/drug effects ; Pregnancy ; Teratogens/toxicity ; Valproic Acid/pharmacology ; Valproic Acid/toxicity
Chemical Substances	Anticonvulsants ; Histamine H3 Antagonists ; Imidazoles ; Methylhistamines ; Teratogens ; histamine H3R antagonist 2-18 ; Valproic Acid (614OI1Z5WI) ; alpha-methylhistamine (6986-90-9)
Language	English
Publishing date	2018-01-19
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2451346-5
ISSN	1177-8881 ; 1177-8881
ISSN (online)	1177-8881
ISSN	1177-8881
DOI	10.2147/DDDT.S144730
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Article ; Online: UAE population reference standard charts for body mass index and skinfold thickness, at ages 0-18 years.

Abdulrazzaq, Yousef M / Nagelkerke, Nico / Moussa, Mohamed A

International journal of food sciences and nutrition

2011 Volume 62, Issue 7, Page(s) 692–702

Abstract: Aims: To determine a range of anthropometric measurements including skinfold thickness measurements in four different areas of the body, to construct population growth charts for body mass index (BMI), skinfolds, and to compare these with growth charts ... ...

Abstract	Aims: To determine a range of anthropometric measurements including skinfold thickness measurements in four different areas of the body, to construct population growth charts for body mass index (BMI), skinfolds, and to compare these with growth charts from other countries. One aim was also to validate body fat charts derived from skinfold thickness. Methods: A national cross-sectional growth survey of children, 0-18 years old, was conducted using multistage stratified random sampling. The sample size included at least 200 children in each age-sex group. Height, weight, biceps skinfold, triceps skinfold, subscapular skinfold, suprailiac skinfold, and mid-upper-arm circumference were measured in each child. We describe correlation, standard deviation scores relative to the other standards, and calculation of body density in the United Arab Emirates population. We determined whether any of the above is a good indicator of fatness in children. Results: BMI, upper-arm circumference, sum of four skinfolds, and percentage body fat charts were constructed using the LMS method of smoothing. BMI was very significantly correlated with sum of skinfold thicknesses, and mid-upper-arm circumference. Prevalence of obesity and overweight in ages 13-17 years was respectively 9.94% and 15.16% in females and 6.08% and 14.16% in males. Derived body fat charts were found not to be accurate. Conclusion: A national BMI, upper-arm circumference, and sum of four skinfolds chart has been constructed that can be used as a reference standard for the United Arab Emirates. Sum of four skinfold thickness charts can be used as crude determinants of adiposity in children, but derived body fat charts were shown to be inaccurate.
MeSH term(s)	Adipose Tissue ; Adolescent ; Anthropometry ; Arm/anatomy & histology ; Body Composition ; Body Mass Index ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Growth Charts ; Humans ; Infant ; Infant, Newborn ; Male ; Obesity/diagnosis ; Obesity/epidemiology ; Overweight/diagnosis ; Overweight/epidemiology ; Prevalence ; Reference Values ; Sex Factors ; Skinfold Thickness ; United Arab Emirates/epidemiology
Language	English
Publishing date	2011-11
Publishing country	England
Document type	Journal Article ; Validation Studies
ZDB-ID	1121877-0
ISSN	1465-3478 ; 0963-7486
ISSN (online)	1465-3478
ISSN	0963-7486
DOI	10.3109/09637486.2011.567978
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Article: UAE population reference standard charts for body mass index and skinfold thickness, at ages 0–18 years

Abdulrazzaq, Yousef M / Nagelkerke, Nico / Moussa, Mohamed A

International journal of food sciences and nutrition. 2011 Nov. 1, v. 62, no. 7

2011

Abstract: Aims To determine a range of anthropometric measurements including skinfold thickness measurements in four different areas of the body, to construct population growth charts for body mass index (BMI), skinfolds, and to compare these with growth charts ... ...

Abstract	Aims To determine a range of anthropometric measurements including skinfold thickness measurements in four different areas of the body, to construct population growth charts for body mass index (BMI), skinfolds, and to compare these with growth charts from other countries. One aim was also to validate body fat charts derived from skinfold thickness. Methods A national cross-sectional growth survey of children, 0–18 years old, was conducted using multistage stratified random sampling. The sample size included at least 200 children in each age–sex group. Height, weight, biceps skinfold, triceps skinfold, subscapular skinfold, suprailiac skinfold, and mid-upper-arm circumference were measured in each child. We describe correlation, standard deviation scores relative to the other standards, and calculation of body density in the United Arab Emirates population. We determined whether any of the above is a good indicator of fatness in children. Results BMI, upper-arm circumference, sum of four skinfolds, and percentage body fat charts were constructed using the LMS method of smoothing. BMI was very significantly correlated with sum of skinfold thicknesses, and mid-upper-arm circumference. Prevalence of obesity and overweight in ages 13–17 years was respectively 9.94% and 15.16% in females and 6.08% and 14.16% in males. Derived body fat charts were found not to be accurate Conclusion A national BMI, upper-arm circumference, and sum of four skinfolds chart has been constructed that can be used as a reference standard for the United Arab Emirates. Sum of four skinfold thickness charts can be used as crude determinants of adiposity in children, but derived body fat charts were shown to be inaccurate.
Keywords	adiposity ; body mass index ; children ; nutrition ; obesity ; population growth ; reference standards ; sample size ; skinfold thickness ; standard deviation ; surveys
Language	English
Dates of publication	2011-1101
Size	p. 692-702.
Publishing place	Taylor & Francis
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	1121877-0
ISSN	1465-3478 ; 0963-7486
ISSN (online)	1465-3478
ISSN	0963-7486
DOI	10.3109/09637486.2011.567978
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis.

Al-Ahmad, Mohammad M / Amir, Naheed / Dhanasekaran, Subramanian / John, Anne / Abdulrazzaq, Yousef M / Ali, Bassam R / Bastaki, Salim M A

PloS one

2017 Volume 12, Issue 9, Page(s) e0183424

Abstract: Cytochrome P450 1A2 (CYP1A2) is one of the CYP450 mixed-function oxidase system that is of clinical importance due to the large number of drug interactions associated with its induction and inhibition. In addition, significant inter-individual ... ...

Abstract	Cytochrome P450 1A2 (CYP1A2) is one of the CYP450 mixed-function oxidase system that is of clinical importance due to the large number of drug interactions associated with its induction and inhibition. In addition, significant inter-individual differences in the elimination of drugs metabolized by CYP1A2 enzyme have been observed which are largely due to the highly polymorphic nature of CYP1A2 gene. However, there are limited studies on CYP1A2 phenotypes and CYP1A2 genotypes among Emiratis and thus this study was carried out to fill this gap. Five hundred and seventy six non-smoker Emirati subjects were asked to consume a soft drink containing caffeine (a non-toxic and reliable probe for predicting CYP1A2 phenotype) and then provide a buccal swab along with a spot urine sample. Taq-Man Real Time PCR was used to determine the CYP1A2 genotype of each individual. Phenotyping was carried out by analyzing the caffeine metabolites using High Performance Liquid Chromatography (HPLC) analysis. We found that 1.4%, 16.3% and 82.3% of the Emirati subjects were slow, intermediate and rapid CYP1A2 metabolizers, respectively. In addition, we found that 1.4% of the subjects were homozygote for derived alleles while 16.1% were heterozygote and 82.5% were homozygote for the ancestral allele. The genotype frequency of the ancestral allele, CYP1A21A/1A, is the highest in this population, followed by CYP1A2 1A/1C and CYP1A2 1A/1K genotypes, with frequencies of 0.825, 0.102 and 0.058, respectively. The degree of phenotype/genotype concordance was equal to 81.6%. The CYP1A21C/1C and CYP1A23/3 genotypes showed significantly the lowest enzyme phenotypic activity. The frequency of slow activity CYP1A2 enzyme alleles is very low among Emiratis which correlates with the presence of low frequencies of derived alleles in CYP1A2 gene.
MeSH term(s)	Adolescent ; Adult ; Caffeine/metabolism ; Cytochrome P-450 CYP1A2/genetics ; Female ; Genotype ; Haplotypes ; Humans ; Male ; Middle Aged ; Phenotype ; Polymorphism, Single Nucleotide ; United Arab Emirates ; Young Adult
Chemical Substances	Caffeine (3G6A5W338E) ; CYP1A2 protein, human (EC 1.14.14.1) ; Cytochrome P-450 CYP1A2 (EC 1.14.14.1)
Language	English
Publishing date	2017
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0183424
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Article ; Online: Studies on N-Acetyltransferase (NAT2) Genotype Relationships in Emiratis: Confirmation of the Existence of Phenotype Variation among Slow Acetylators.

Al-Ahmad, Mohammad M / Amir, Naheed / Dhanasekaran, Subramanian / John, Anne / Abdulrazzaq, Yousef M / Ali, Bassam R / Bastaki, Salim

Annals of human genetics

2017 Volume 81, Issue 5, Page(s) 190–196

Abstract: Background and purpose: Individuals with slow N-acetylation phenotype often experience toxicity from drugs such as isoniazid, sulfonamides, procainamide, and hydralazine, whereas rapid acetylators may not respond to these medications. The highly ... ...

Abstract	Background and purpose: Individuals with slow N-acetylation phenotype often experience toxicity from drugs such as isoniazid, sulfonamides, procainamide, and hydralazine, whereas rapid acetylators may not respond to these medications. The highly polymorphic N-acetyltransferase 2 enzyme encoded by the NAT2 gene is one of the N-acetylators in humans with a clear impact on the metabolism of a significant number of important drugs. However, there are limited studies on N-acetylation phenotypes and NAT2 genotypes among Emiratis, and thus this study was carried out to fill this gap. Methods: Five hundred seventy-six Emirati subjects were asked to consume a soft drink containing caffeine (a nontoxic and reliable probe for predicting the acetylation phenotype) and then provide a buccal swab along with a spot urine sample. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to determine the genotype of each individual. Phenotyping was carried out by analyzing the caffeine metabolites using high-performance liquid chromatography (HPLC) analysis. Results: We found that 78.5%, 19.1%, and 2.4% of the Emirati subjects were slow, intermediate, and rapid acetylators, respectively. In addition, we found that 77.4% of the subjects were homozygous or heterozygous for two nonreference alleles, whereas 18.4% and 4.2% were heterozygous or homozygous for the reference allele (NAT24), respectively. The most common genotypes found were NAT25B/7B, NAT25B/6A, NAT27B/14B, and NAT24/5B, with frequencies of 0.255, 0.135, 0.105, and 0.09, respectively. The degree of phenotype/genotype concordance was 96.2%. The NAT26A/6A, NAT26A/7B, NAT27B/7B, and NAT25A/5B genotypes were found to be associated with the lowest 5-acetylamino-6-formylamino-3-methyluracil/1-methylxanthine (AFMU/1X) ratios. Conclusions:* There is a high percentage of slow acetylators among Emiratis, which correlates with the presence of nonreference alleles for the NAT2 gene. Individuals who carried NAT26A/6A, NAT26A/7B, NAT27B/7B, or NAT25A/5B genotypes might be at higher risk of toxicity with some drugs and some diseases compared to others, as these genotypes are associated with the slowest acetylation status.
Language	English
Publishing date	2017-09
Publishing country	England
Document type	Journal Article
ZDB-ID	333-5
ISSN	1469-1809 ; 0003-4800
ISSN (online)	1469-1809
ISSN	0003-4800
DOI	10.1111/ahg.12198
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Article ; Online: National growth charts for United Arab Emirates children with Down syndrome from birth to 15 years of age.

Aburawi, Elhadi H / Nagelkerke, Nicolas / Deeb, Asma / Abdulla, Shahrban / Abdulrazzaq, Yousef M

Journal of epidemiology

2014 Volume 25, Issue 1, Page(s) 20–29

Abstract: Background: Specific centile growth charts for children with Down syndrome (DS) have been produced in many countries and are known to differ from those of normal children. Since growth assessment depends on the growth pattern characteristic for these ... ...

Abstract	Background: Specific centile growth charts for children with Down syndrome (DS) have been produced in many countries and are known to differ from those of normal children. Since growth assessment depends on the growth pattern characteristic for these conditions, disorder-specific charts are desirable for various ethnic groups. Aims: To provide cross-sectional weight, height, and head circumference (HC) references for healthy United Arab Emirates (UAE) children with DS. Methods: A retrospective and cross-sectional growth study of Emirati children with DS, aged 0 to 18 years old, was conducted. Height, weight, and HC were measured in each child. Cole's LMS statistical method was applied to estimate age-specific percentiles, and measurements were compared to UAE reference values for normal children. Results: Incidence of DS in the UAE population is 1 in 374 live births (267 in 10 000 live births). We analyzed 1263 growth examinations of 182 children with DS born between 1994 and 2012. The male-to-female ratio was 1.6:1. Height, weight, and HC centile charts were constructed for ages 0 to 13 years. The prevalence of overweight and obesity in DS children aged 10 to 13 years of age was 32% and 19%, respectively. The DS children were significantly shorter and heavier than normal children in the UAE. Conclusions: Weight, height, and HC growth charts were created for children with DS. These can be used as a reference standard for the UAE children with DS. Overweight and obesity are quite common in DS children ≥ 10 years of age, as DS children tend to be shorter and heavier than non-DS children.
MeSH term(s)	Adolescent ; Body Height/physiology ; Body Weight/physiology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Down Syndrome/epidemiology ; Down Syndrome/physiopathology ; Female ; Growth Charts ; Head/growth & development ; Humans ; Infant ; Infant, Newborn ; Male ; Overweight/epidemiology ; Pediatric Obesity/epidemiology ; Retrospective Studies ; United Arab Emirates/epidemiology
Language	English
Publishing date	2014-09-06
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1442118-5
ISSN	1349-9092 ; 0917-5040
ISSN (online)	1349-9092
ISSN	0917-5040
DOI	10.2188/jea.JE20130081
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Article ; Online: National growth charts for the United Arab Emirates.

Abdulrazzaq, Yousef M / Moussa, Mohamed A / Nagelkerke, Nicolaas

Journal of epidemiology

2008 Volume 18, Issue 6, Page(s) 295–303

Abstract: Background: Information on the health and growth status of the population is essential for planning and administering health promotion programs.: Methods: This is a cross-sectional study of the anthropometric measurements of United Arab Emirates (UAE) ...

Abstract	Background: Information on the health and growth status of the population is essential for planning and administering health promotion programs. Methods: This is a cross-sectional study of the anthropometric measurements of United Arab Emirates (UAE) children aged 0-18 years, by a multistage stratified random sampling technique based on age and sex. Healthy, full-term children of UAE nationality who did not have any diseases that could affect their growth pattern were included in the study. Children were selected using multistage sampling, using sampling proportional to size methods in 9 geographical areas. Growth charts for various anthropometric measures were created using Cole's LMS statistical package. This package estimates age-specific percentiles with the use of smoothing splines after transformation to normality. Results: A total of 21,068 children (12,159 females) between the ages of 0 and 18 years were studied. In the present study, we included 8-15% of the population aged 0-18 years. The growth chart for 0-36 months is very similar to the NCHS growth reference chart in terms of both weight for age and length and height for age. The mean (+SD) length/height in children was 49.9 +/- 3.2 cm at birth, 75.9 +/- 5.7 cm at 12 months, 86.4 +/- 4.5 cm at 24 months, 95.1 +/- 5.9 cm at 36 months, and 111.1 +/- 6.4 cm at 60 months. The height of UAE children in the first 3 years of life, especially at the ages of 2 and 3 years, mirrored those achieved by Brazilian children in the WHO study. Conclusion: The results of the present study are useful for growth assessment of UAE children.
MeSH term(s)	Adolescent ; Anthropometry ; Body Height ; Body Mass Index ; Body Weight ; Cephalometry/statistics & numerical data ; Child ; Child Development ; Child, Preschool ; Cross-Sectional Studies ; Female ; Growth ; Growth Disorders/epidemiology ; Humans ; Infant ; Infant, Newborn ; Male ; Reference Values ; Sampling Studies ; United Arab Emirates/epidemiology
Language	English
Publishing date	2008-12-09
Publishing country	Japan
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	1442118-5
ISSN	1349-9092 ; 0917-5040
ISSN (online)	1349-9092
ISSN	0917-5040
DOI	10.2188/jea.je2008037
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