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  1. Article ; Online: Advances in inhaled antibiotics for management of respiratory tract infections.

    Riveiro, Vanessa / Casal, Ana / Abelleira, Romina / Valdés, Luis

    Current opinion in pulmonary medicine

    2023  Volume 29, Issue 3, Page(s) 160–167

    Abstract: Purpose of review: The incidence of bacterial respiratory tract infections is growing. In a context of increasing antibiotic resistance and lack of new classes of antibiotics, inhaled antibiotics emerge as a promising therapeutic strategy. Although they ...

    Abstract Purpose of review: The incidence of bacterial respiratory tract infections is growing. In a context of increasing antibiotic resistance and lack of new classes of antibiotics, inhaled antibiotics emerge as a promising therapeutic strategy. Although they are generally used for cystic fibrosis, their use in other conditions is becoming more frequent, including no-cystic fibrosis bronchiectasis, pneumonia and mycobacterial infections.
    Recent findings: Inhaled antibiotics exert beneficial microbiological effects in bronchiectasis and chronic bronchial infection. In nosocomial and ventilator-associated pneumonia, aerosolized antibiotics improve cure rates and bacterial eradication. In refractory Mycobacterium avium complex infections, amikacin liposome inhalation suspension is more effective in achieving long-lasting sputum conversion. In relation to biological inhaled antibiotics (antimicrobial peptides, interfering RNA and bacteriophages), currently in development, there is no still enough evidence that support their use in clinical practice.
    Summary: The effective antimicrobiological activity of inhaled antibiotics, added to their potential to overcoming resistances to systemic antibiotics, make inhaled antibiotics a plausible alternative.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Administration, Inhalation ; Respiratory Tract Infections/microbiology ; Amikacin/therapeutic use ; Bronchiectasis/drug therapy ; Bronchiectasis/complications
    Chemical Substances Anti-Bacterial Agents ; Amikacin (84319SGC3C)
    Language English
    Publishing date 2023-03-03
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000000952
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  2. Article ; Online: Primary pleural schwannoma: A rare cause of extrapleural lesion.

    Abelleira, Romina / Ferreiro, Lucía / Valdés, Luis

    Medicina clinica

    2020  Volume 157, Issue 1, Page(s) 48–49

    Language Spanish
    Publishing date 2020-08-21
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.04.061
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  3. Article ; Online: Positional Nasal Congestion. Sleep Apnea's Forgotten Cousin.

    Calvo-Henríquez, Christian / Abelleira, Romina / González-Barcala, Francisco J

    Archivos de bronconeumologia

    2021  

    Title translation La congestión nasal posicional. El hermano olvidado de la apnea del sueño.
    Language Spanish
    Publishing date 2021-01-04
    Publishing country Spain
    Document type Editorial
    ZDB-ID 2591346-3
    ISSN 2173-5751 ; 2173-5751
    ISSN (online) 2173-5751
    ISSN 2173-5751
    DOI 10.1016/j.arbres.2020.12.011
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  4. Article ; Online: Positional nasal congestion. Sleep apnea's forgotten cousin.

    Calvo-Henríquez, Christian / Abelleira, Romina / González-Barcala, Francisco J

    Archivos de bronconeumologia

    2021  Volume 57, Issue 7, Page(s) 453–454

    MeSH term(s) Humans ; Respiratory System Abnormalities ; Sleep ; Sleep Apnea Syndromes/etiology
    Language English
    Publishing date 2021-05-15
    Publishing country Spain
    Document type Editorial
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbr.2021.05.004
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  5. Article ; Online: Relationship between obstructive sleep apnea and type 2 diabetes mellitus.

    Abelleira, Romina / Zamarrón, Carlos / Riveiro, Vanessa / Casal, Ana / Toubes, María Elena / Rábade, Carlos / Ricoy, Jorge / Lama, Adriana / Rodríguez-Núñez, Nuria / Ferreiro, Lucía / Rodríguez-Ozores, Juan / Valdés, Luis

    Medicina clinica

    2024  Volume 162, Issue 8, Page(s) 363–369

    Abstract: Introduction: The association between obstructive sleep apnea (OSA) and glucose metabolism remains controversial. This study investigates the relationship between OSA and incident type 2 diabetes (DM) and prediabetes (preDM), as well as the effect of ... ...

    Title translation Relación entre la apnea obstructiva del sueño y la diabetes mellitus tipo 2.
    Abstract Introduction: The association between obstructive sleep apnea (OSA) and glucose metabolism remains controversial. This study investigates the relationship between OSA and incident type 2 diabetes (DM) and prediabetes (preDM), as well as the effect of long-term CPAP (continuous positive airway pressure) treatment.
    Methods: Follow-up study in a retrospective clinical cohort of patients with OSA and randomly selected controls. Data on incident DM and preDM as well as CPAP were obtained from hospital records. The relationship between baseline OSA and incident DM was examined using COX regression models.
    Results: Three hundred and fifty-six patients, 169 with OSA and 187 controls were followed for a median of 98 months; 47 patients (13.2%) developed DM and 43 (12.1%) developed preDM. The 5-year cumulative incidence of DM was 10.7% (6.5-13.9%). 87% of subjects with preDM in the baseline sample progressed to incident DM. It is shown that body mass index (BMI), nocturnal hypoxia and apnea hypopnea index (AHI) are risk factors for the development of DM and that CPAP reduces this risk.
    Conclusions: Patients with OSA have a higher risk of developing DM. The risk factors involved are BMI, nocturnal hypoxia and AHI. Regular long-term CPAP use was associated with a decreased risk.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Retrospective Studies ; Follow-Up Studies ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/therapy ; Prediabetic State ; Continuous Positive Airway Pressure ; Hypoxia
    Language Spanish
    Publishing date 2024-01-13
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2023.11.014
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  6. Article ; Online: Diabetes y apnea obstructiva del sueño. Un estudio de casos y controles.

    Abelleira, Romina / Zamarrón, Carlos / Riveiro, Vanessa / Casal, Ana / Toubes, María E / Rábade, Carlos / Ricoy, Jorge / Lama, Adriana / Rodríguez-Núñez, Nuria / Ferreiro, Lucía / Valdés, Luis

    Medicina clinica

    2023  Volume 162, Issue 2, Page(s) 49–55

    Abstract: Introduction: Obstructive sleep apnoea (OSA) and diabetes mellitus (DM) are very prevalent diseases frequently associated. Their coexistence is independently associated with an increased prevalence of cardiovascular comorbidities. As this association is ...

    Title translation Diabetes and obstructive sleep apnoea: A case-control study.
    Abstract Introduction: Obstructive sleep apnoea (OSA) and diabetes mellitus (DM) are very prevalent diseases frequently associated. Their coexistence is independently associated with an increased prevalence of cardiovascular comorbidities. As this association is underdiagnosed, it is necessary to optimise clinical suspicion by studying independent predictors of DM or prediabetes (preDM) in patients with OSA.
    Method: A simple randomised case-control study, matched for sex, body mass index (BMI) and age, aimed to study the association of OSA with DM and preDM and to identify independent predictors for both diseases in people with OSA.
    Results: We included 208 cases with OSA and 208 controls without OSA. In the former, 18.8% had DM compared to only 10.1% in the latter (P=.00). Prevalence of preDM was 41.8% vs. 10.6%, respectively (P=.00). One hundred and twenty-four cases (59.6%) reported excessive daytime sleepiness (EDS) (Epworth scale, 10.5±3.1) vs. 24.5% of the control group (Epworth scale, 6.6±2.9). Apnoea-hypopnoea index (AHI) and O
    Conclusions: OSA is associated with DM and preDM. Age, nocturnal hypoxaemia and EDS are predictors of DM. BMI and AHI are predictors of pre-MD.
    MeSH term(s) Humans ; Case-Control Studies ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/diagnosis ; Sleep Apnea, Obstructive/epidemiology ; Diabetes Mellitus/epidemiology ; Comorbidity ; Prediabetic State/epidemiology ; Hypoxia/epidemiology
    Language Spanish
    Publishing date 2023-10-03
    Publishing country Spain
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2023.07.031
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  7. Article ; Online: Late biliobronchial fistula.

    Abelleira, Romina / Toubes, María Elena / Alegría, Anxo Martínez de / Valdés, Luis

    Pulmonology

    2018  Volume 24, Issue 5, Page(s) 317–320

    MeSH term(s) Aged, 80 and over ; Biliary Fistula/diagnosis ; Biliary Fistula/etiology ; Biliary Fistula/therapy ; Bronchial Fistula/diagnosis ; Bronchial Fistula/etiology ; Bronchial Fistula/therapy ; Fatal Outcome ; Humans ; Male
    Language English
    Publishing date 2018-09-22
    Publishing country Spain
    Document type Case Reports ; Letter
    ISSN 2531-0437
    ISSN (online) 2531-0437
    DOI 10.1016/j.pulmoe.2018.08.001
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  8. Article ; Online: Reversible diffuse lung disease after mycophenolate mofetil withdrawal.

    Abelleira, Romina / Elena Toubes, María / Suárez-Antelo, Juan / Valdés, Luis

    Pulmonology

    2018  Volume 24, Issue 6, Page(s) 361–362

    MeSH term(s) Aged ; Female ; Humans ; Lung Diseases, Interstitial/chemically induced ; Mycophenolic Acid/adverse effects ; Mycophenolic Acid/therapeutic use ; Remission Induction ; Withholding Treatment
    Chemical Substances Mycophenolic Acid (HU9DX48N0T)
    Language English
    Publishing date 2018-12-14
    Publishing country Spain
    Document type Case Reports ; Letter
    ISSN 2531-0437
    ISSN (online) 2531-0437
    DOI 10.1016/j.pulmoe.2018.10.003
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  9. Article ; Online: Health Indicators in Hospitalized Patients With SARS-CoV-2 Pneumonia: A Comparison Between the First and Second Wave.

    Rodríguez-Núñez, Nuria / Gude, Francisco / Lama, Adriana / Rábade, Carlos / Varela, Alfonso / Abelleira, Romina / Casal, Ana / Riveiro, Vanessa / Taboada, Manuel / Pose, Antonio / Valdés, Luis

    Archivos de bronconeumologia

    2021  Volume 57, Issue 11, Page(s) 717–719

    Language English
    Publishing date 2021-03-23
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2021.03.012
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  10. Article ; Online: Health Indicators in Hospitalized Patients With SARS-CoV-2 Pneumonia: A Comparison Between the First and Second Wave.

    Rodríguez-Núñez, Nuria / Gude, Francisco / Lama, Adriana / Rábade, Carlos / Varela, Alfonso / Abelleira, Romina / Casal, Ana / Riveiro, Vanessa / Taboada, Manuel / Pose, Antonio / Valdés, Luis

    Archivos de bronconeumologia

    2021  

    Language Spanish
    Publishing date 2021-03-23
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2591346-3
    ISSN 2173-5751 ; 2173-5751
    ISSN (online) 2173-5751
    ISSN 2173-5751
    DOI 10.1016/j.arbres.2021.03.012
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