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  1. Article ; Online: Heterogeneity in patterns of progression of chronic kidney disease.

    Abeysekera, Rajitha A / Healy, Helen G / Wang, Zaimin / Cameron, Anne L / Hoy, Wendy E

    Internal medicine journal

    2020  Volume 51, Issue 2, Page(s) 220–228

    Abstract: Background: Progression of kidney disease is a deceptively simple word for a complex bio-clinical process, evidenced by the number of definitions in the literature. This has led to confusion and differences in interpretation of studies.: Methods: We ... ...

    Abstract Background: Progression of kidney disease is a deceptively simple word for a complex bio-clinical process, evidenced by the number of definitions in the literature. This has led to confusion and differences in interpretation of studies.
    Methods: We describe different patterns of progression, the performance of different definitions of progression and factors associated with chronic kidney disease (CKD) progression in a public renal service in Australia, in a study of patients enrolled in the CKD.QLD Registry with a minimum of 2 years' follow up.
    Results: Nine patterns of changing estimated glomerular filtration rate (eGFR) over two consecutive 12-month periods were identified. Most common was a stable eGFR over 2 years (30%), and the least was a sustainable improvement of eGFR over both periods (2.1%). There was a lack of congruence between the several definitions of progression of CKD evaluated. More people progressed using the definition of decline of eGFR of >5 mL/min/1.73 m
    Conclusions: This is one of the first demonstrations of the great variations among and within individuals in the progression of CKD over even a period as short as 2 years. Findings suggest considerable potential for renal function recovery and stability while demonstrating the importance of using identical definitions for comparisons across datasets from different sources.
    MeSH term(s) Australia/epidemiology ; Child, Preschool ; Disease Progression ; Glomerular Filtration Rate ; Humans ; Kidney Failure, Chronic ; Proteinuria/epidemiology ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Risk Factors
    Language English
    Publishing date 2020-02-06
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.14770
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A toolkit for ISN's registry initiative, SharE-RR.

    Pippias, Maria / Abeysekera, Rajitha A / Arruebo, Silvia / Davids, M Razeen / Damster, Sandrine / Gonzales-Bedat, Maria C / Hanafusa, Norio / Hoshino, Junichi / Hradsky, Anne / Irish, Georgina L / Jager, Kitty J / Karam, Sabine / Kumar, Vivek / McDonald, Stephen P / Rosa-Diez, Guillermo J / Tannor, Elliot K / Wetmore, James B / Caskey, Fergus J

    Kidney international

    2024  Volume 105, Issue 4, Page(s) 646–648

    MeSH term(s) Registries ; Nephrology
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2024.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Use of Complementary and Alternative Medicines (CAMs) among type 2 diabetes patients in Sri Lanka: a cross sectional survey

    Medagama, Arjuna B / Bandara, Ruwanthi / Abeysekera, Rajitha A / Imbulpitiya, Buddhini / Pushpakumari, Thamudika

    BMC Complement Altern Med. 2014 Dec., v. 14, no. 1 p.374-374

    2014  

    Abstract: BACKGROUND: The incidence of chronic illnesses has increased worldwide. Diabetes is one such illness and 80% of the diabetic population lives in the developing world. There is a rapidly growing trend towards the use of Complementary and Alternative ... ...

    Abstract BACKGROUND: The incidence of chronic illnesses has increased worldwide. Diabetes is one such illness and 80% of the diabetic population lives in the developing world. There is a rapidly growing trend towards the use of Complementary and Alternative Medical practices in Diabetes. Sri Lanka is a developing Asian nation with a rich culture of Ayurvedic and native medical culture. The objective of this study was to find the prevalence of use of CAMs in a diabetic population attending a large multiethnic diabetes facility in a University unit and to assess whether there is an increase in the incidence of hypoglycaemic episodes among users of CAMs. METHODS: A cross sectional study was performed at Teaching Hospital Peradeniya between April and August 2012. Following verbal consent, 254 type 2 adult diabetic patients attending the diabetes facility were interviewed regarding the use of CAM and hypoglycaemia using an interviewer-administered questionnaire. RESULTS: Of the 252 valid results, 192 patients (76%) admitted to the use of a CAM to reduce blood glucose. Bitter gourd, ivy gourd and crepe ginger were used by 128, 113 and 92 individuals. While 19% used a single agent, 34%, 21% and 2.4% used 2,3 and more than 3 agents. The incidence of hypoglycaemia in CAM users was 21% and 16.6% in non-users. The difference was statistically not significant. (p = 0.57) Ingestion of Costus speciosus (Crepe ginger) was associated with higher incidence of hypoglycaemia (P = 0.01). Female gender was significantly associated with CAM use (p = 0.01), while the age, duration of diabetes, presence of co-morbidities and complications of diabetes failed to show a significant association. CONCLUSION: Sri Lanka has a very high use of herbal supplementation in type 2 diabetes patients. Although the overall incidence of hypoglycaemia is not increased among CAM users, crepe ginger is associated with significant hypoglycaemia and warrants further research.
    Keywords Cheilocostus speciosus ; Coccinia grandis ; Momordica charantia ; adults ; blood glucose ; complement ; cross-sectional studies ; females ; hospitals ; hypoglycemia ; ingestion ; nationalities and ethnic groups ; noninsulin-dependent diabetes mellitus ; questionnaires ; Sri Lanka
    Language English
    Dates of publication 2014-12
    Size p. 374.
    Publishing place BioMed Central
    Document type Article ; Online
    Note Resource is Open Access
    ZDB-ID 2050429-9
    ISSN 1472-6882
    ISSN 1472-6882
    DOI 10.1186/1472-6882-14-374
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Use of Complementary and Alternative Medicines (CAMs) among type 2 diabetes patients in Sri Lanka: a cross sectional survey.

    Medagama, Arjuna B / Bandara, Ruwanthi / Abeysekera, Rajitha A / Imbulpitiya, Buddhini / Pushpakumari, Thamudika

    BMC complementary and alternative medicine

    2014  Volume 14, Page(s) 374

    Abstract: Background: The incidence of chronic illnesses has increased worldwide. Diabetes is one such illness and 80% of the diabetic population lives in the developing world. There is a rapidly growing trend towards the use of Complementary and Alternative ... ...

    Abstract Background: The incidence of chronic illnesses has increased worldwide. Diabetes is one such illness and 80% of the diabetic population lives in the developing world. There is a rapidly growing trend towards the use of Complementary and Alternative Medical practices in Diabetes. Sri Lanka is a developing Asian nation with a rich culture of Ayurvedic and native medical culture. The objective of this study was to find the prevalence of use of CAMs in a diabetic population attending a large multiethnic diabetes facility in a University unit and to assess whether there is an increase in the incidence of hypoglycaemic episodes among users of CAMs.
    Methods: A cross sectional study was performed at Teaching Hospital Peradeniya between April and August 2012. Following verbal consent, 254 type 2 adult diabetic patients attending the diabetes facility were interviewed regarding the use of CAM and hypoglycaemia using an interviewer-administered questionnaire.
    Results: Of the 252 valid results, 192 patients (76%) admitted to the use of a CAM to reduce blood glucose. Bitter gourd, ivy gourd and crepe ginger were used by 128, 113 and 92 individuals. While 19% used a single agent, 34%, 21% and 2.4% used 2,3 and more than 3 agents. The incidence of hypoglycaemia in CAM users was 21% and 16.6% in non-users. The difference was statistically not significant. (p = 0.57) Ingestion of Costus speciosus (Crepe ginger) was associated with higher incidence of hypoglycaemia (P = 0.01).Female gender was significantly associated with CAM use (p = 0.01), while the age, duration of diabetes, presence of co-morbidities and complications of diabetes failed to show a significant association.
    Conclusion: Sri Lanka has a very high use of herbal supplementation in type 2 diabetes patients. Although the overall incidence of hypoglycaemia is not increased among CAM users, crepe ginger is associated with significant hypoglycaemia and warrants further research.
    MeSH term(s) Aged ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/therapy ; Female ; Humans ; Male ; Middle Aged ; Phytotherapy/statistics & numerical data ; Plants, Medicinal ; Sri Lanka/epidemiology
    Language English
    Publishing date 2014-10-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050429-9
    ISSN 1472-6882 ; 1472-6882
    ISSN (online) 1472-6882
    ISSN 1472-6882
    DOI 10.1186/1472-6882-14-374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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