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  1. AU="Abichandani, Deepa"
  2. AU="Piccinelli, Fabio"
  3. AU="Malinova, Tsveta S"
  4. AU="Harwood, Janet"
  5. AU=Buscombe John R
  6. AU=Meyer-Rusenberg Birthe
  7. AU="Jiang, Weiyan"
  8. AU="Mills, W"
  9. AU="Pintó, Rosa M."
  10. AU="Voisin, Tiphaine"
  11. AU="Takahashi, Hiromi"
  12. AU="Lin, Johnny"
  13. AU="Lee, Yu-Ru"
  14. AU="Safrankova, J."
  15. AU="Lanting, Linda L"
  16. AU=Koushik Nikhil S
  17. AU="Culhane, John"
  18. AU="Chippada, Appa Rao"
  19. AU="Hiroki Sato" AU="Hiroki Sato"
  20. AU="Al-Amer Eshraq"
  21. AU="Thanacoody, Ruben"
  22. AU="Lin, Chi-Wei"
  23. AU="Chidambaram, Vignesh"

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  1. Artikel ; Online: Measures of neck muscle strength and their measurement properties in adults with chronic neck pain-a systematic review.

    Abichandani, Deepa / Ting, Jonathan Tong Yuk / Cancino, Edith Elgueta / Althobaiti, Shouq / Falla, Deborah

    Systematic reviews

    2023  Band 12, Heft 1, Seite(n) 6

    Abstract: Background: Measurement of neck muscle strength is common during the assessment of people with chronic neck pain (CNP). This systematic review evaluates the measurement properties (reliability, validity, and responsiveness) of neck muscle strength ... ...

    Abstract Background: Measurement of neck muscle strength is common during the assessment of people with chronic neck pain (CNP). This systematic review evaluates the measurement properties (reliability, validity, and responsiveness) of neck muscle strength measures in people with CNP.
    Databases and data treatment: This systematic review followed a PROSPERO registered protocol (CRD42021233290). Electronic databases MEDLINE (OVID interface), CINAHL, SPORTDiscuss via (EBSCO interface), EMBASE (OVID interface), and Web of Science were searched from inception to 21 June 2021. Screening, data extraction, and quality assessment (Consensus-based Standards for the selection of Health Measurement Instruments (COSMIN) checklist) were conducted independently by two reviewers. The overall strength of evidence was evaluated using the modified Grading of Recommendations Assessment, Development and Evaluation.
    Results: From 794 records, nine articles were included in this review which concerned six different neck strength outcome measures. All studies evaluated reliability and one evaluated construct validity. The reliability of neck strength measures ranged from good to excellent. However, the risk of bias was rated as doubtful/inadequate for all except one study and the overall certainty of evidence was rated low/very low for all measures except for the measurement error of a handheld dynamometer.
    Conclusion: A multitude of measures are used to evaluate neck muscle strength in people with CNP, but their measurement properties have not been fully established. Further methodologically rigorous research is required to increase the overall quality of evidence.
    Mesh-Begriff(e) Humans ; Adult ; Neck Pain ; Reproducibility of Results ; Muscle Strength ; Outcome Assessment, Health Care ; Checklist
    Sprache Englisch
    Erscheinungsdatum 2023-01-16
    Erscheinungsland England
    Dokumenttyp Systematic Review ; Journal Article
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-022-02162-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: A meta-analysis and systematic review of changes in joint position sense and static standing balance in patients with whiplash-associated disorder.

    Mazaheri, Masood / Abichandani, Deepa / Kingma, Idsart / Treleaven, Julia / Falla, Deborah

    PloS one

    2021  Band 16, Heft 4, Seite(n) e0249659

    Abstract: Objective: To synthesise and analyse the current evidence regarding changes in joint position sense (JPS) and standing balance in people with whiplash-associated disorder (WAD) taking the presence or absence of dizziness into account.: Data sources: ... ...

    Abstract Objective: To synthesise and analyse the current evidence regarding changes in joint position sense (JPS) and standing balance in people with whiplash-associated disorder (WAD) taking the presence or absence of dizziness into account.
    Data sources: PubMed, CINAHL Plus, Web of Science, Embase, MEDLINE and APA PsycINFO were searched by two independent reviewers from inception until August 2020 and reference lists of all included studies were also reviewed.
    Study selection: Only cross-sectional studies that measured JPS and/or standing balance between people with WAD vs. healthy controls (HC) or people with WAD complaining of dizziness (WADD) vs. those not complaining of dizziness (WADND) were selected.
    Data extraction: Relevant data were extracted using specific checklists and quality assessment was performed using Downs and Black Scale (modified version).
    Data synthesis: Twenty-six studies were included. For JPS, data were synthesized for absolute error in the primary plane of movement for separate movement directions. For standing balance, data were synthesized for traditional time- and frequency domain sway parameters considering the conditions of eyes open (EO) and eyes closed (EC) separately. For meta-analysis, reduced JPS was observed in people with WAD compared to HC when the head was repositioned to a neutral head position (NHP) from rotation (standardised mean difference [SMD] = 0.43 [95%: 0.24-0.62]) and extension (0.33 [95%CI: 0.08-0.58]) or when the head was moved toward 50° rotation from a NHP (0.50 [0.05-0.96]). Similarly, people with WADD had reduced JPS compared to people with WADND when the head was repositioned to a NHP from rotation (0.52 [0.22-0.82]). Larger sway velocity and amplitude was found in people with WAD compared to HC for both EO (0.62 [0.37-0.88] and 0.78 [0.56-0.99], respectively) and EC (0.69 [0.46-0.91] and 0.80 [0.58-1.02]) conditions.
    Conclusion: The observed changes of JPS and standing balance confirms deficits in sensorimotor control in people with WAD and especially in those with dizziness.
    Mesh-Begriff(e) Animals ; Cross-Sectional Studies ; Dizziness/physiopathology ; Head/physiopathology ; Humans ; Movement/physiology ; Postural Balance/physiology ; Whiplash Injuries/physiopathology
    Sprache Englisch
    Erscheinungsdatum 2021-04-08
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0249659
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Individuals with patellofemoral pain syndrome have altered inter-leg force coordination.

    Liew, Bernard X W / Abichandani, Deepa / De Nunzio, Alessandro Marco

    Gait & posture

    2020  Band 79, Seite(n) 65–70

    Abstract: Background: Patellofemoral pain syndrome (PFPS) is one of the most common musculoskeletal disorders. Pain may be further exacerbated by atypical motor coordination strategies. It has been thought that low coordination variability may concentrate loads ... ...

    Abstract Background: Patellofemoral pain syndrome (PFPS) is one of the most common musculoskeletal disorders. Pain may be further exacerbated by atypical motor coordination strategies. It has been thought that low coordination variability may concentrate loads onto painful knee tissues.
    Research question: To investigate if inter-limb force coordination is altered between individuals with and without PFPS.
    Methods: 31 individuals (control = 17, PFPS = 14) performed bilateral vertical hopping, on two force plates at three frequencies (2.2, 2.6, 3.0 Hz). Uncontrolled manifold analysis (UCM) was used to provide an index of motor abundance (IMA) in the coordination of inter-limb forces to stabilize the two-limb's total force. UCM was applied to the study of forces in each plane (medial-lateral (ML), anterior-posterior (AP), vertical). Bayesian Functional Data Analysis was used for statistical inference. We calculated the mean (u) with 95 % credible interval (CrI) of the difference ΔIMA
    Results: Individuals with PFPS had the greatest significant decrement from controls at 6% of stance hopping at 2.6 Hz by a mean difference of -0.23 for ML GRF; at 19 % of stance hopping at 2.2 Hz by a mean difference of -0.14 for AP GRF; and 52 % of stance hopping at 2.6 Hz by a mean difference of -0.14 for vertical GRF. For vertical GRF, there was a > 0.95 probability that controls had greater IMA than individuals with PFPS hopping between 12-13% of stance at 2.2 Hz, and between 48-55% at 2.6 Hz.
    Significance: Individuals with PFPS have reduced inter-leg force coordination for impact force attenuation and body support, compared to asymptomatic controls. The present study provides insights into a plausible mechanism underpinning persistent knee pain which could be used in the development of novel rehabilitative approaches for individuals with PFPS.
    Mesh-Begriff(e) Adolescent ; Adult ; Bayes Theorem ; Biomechanical Phenomena ; Case-Control Studies ; Female ; Humans ; Leg/physiopathology ; Male ; Middle Aged ; Movement ; Patellofemoral Pain Syndrome/physiopathology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-04-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2020.04.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Microscopic changes in the spinal extensor musculature in people with chronic spinal pain: a systematic review.

    Purushotham, Shilpa / Stephenson, Rob S / Sanderson, Andy / Abichandani, Deepa / Greig, Carolyn / Gardner, Adrian / Falla, Deborah

    The spine journal : official journal of the North American Spine Society

    2022  Band 22, Heft 7, Seite(n) 1205–1221

    Abstract: Background context: Chronic spinal pain is one the most common musculoskeletal disorders. Previous studies have observed microscopic structural changes in the spinal extensor muscles in people with chronic spinal pain. This systematic review synthesizes ...

    Abstract Background context: Chronic spinal pain is one the most common musculoskeletal disorders. Previous studies have observed microscopic structural changes in the spinal extensor muscles in people with chronic spinal pain. This systematic review synthesizes and analyzes all the existing evidence of muscle microscopic changes in people with chronic spinal pain.
    Purpose: To assess the microscopy of spinal extensor muscles including the fiber type composition, the area occupied by fiber types, fiber size/cross sectional area (CSA), and narrow diameter (ND) in people with and without chronic spinal pain. Further, to compare these outcome measures across different regions of the spine in people with chronic neck, thoracic and low back pain.
    Study design: Systematic review with meta-analysis.
    Methods: MEDLINE (Ovid Interface), Embase, PubMed, CINAHL Plus, and Web of Science were searched from inception to October 2020. Key journals, conference proceedings, grey literature and hand searching of reference lists from eligible studies were also searched. Two independent reviewers were involved in the selection process. Only studies examining the muscle microscopy of the spinal extensor muscles (erector spinae [ES] and/or multifidus [MF]) between people with and without chronic spinal pain were selected. The risk of bias from the studies was assessed using modified Newcastle Ottawa Scale and the level of evidence was established using the GRADE approach. Data were synthesized based on homogeneity on the methodology and outcome measures of the studies for ES and MF muscles and only four studies were eligible for analysis.
    Results: All the five studies included were related to chronic low back pain (CLBP). Meta-analysis (inverse variance method for random effect to calculate mean difference and 95% CI) was performed for the ES fiber type composition by numbers for both type I and type II fibers (I
    Conclusions: For the ES muscle, there was no difference in fiber type composition and fiber CSA between people with and without CLBP and no conclusions could be drawn for ND for the ES. For the MF, no conclusions could be drawn for any of the muscle microscopy outcome measures. Overall, the quality of evidence is very low and there is very low evidence that there are no differences in microscopic muscle features between people with and without CLBP.
    Mesh-Begriff(e) Chronic Pain ; Humans ; Low Back Pain ; Paraspinal Muscles ; Spine
    Sprache Englisch
    Erscheinungsdatum 2022-02-05
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 2037072-6
    ISSN 1878-1632 ; 1529-9430
    ISSN (online) 1878-1632
    ISSN 1529-9430
    DOI 10.1016/j.spinee.2022.01.023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Measures of central sensitization and their measurement properties in musculoskeletal trauma: A systematic review.

    Middlebrook, Nicola / Rushton, Alison B / Abichandani, Deepa / Kuithan, Pauline / Heneghan, Nicola R / Falla, Deborah

    European journal of pain (London, England)

    2020  Band 25, Heft 1, Seite(n) 71–87

    Abstract: Background and objective: Chronic pain following musculoskeletal trauma is common, which may partially be attributed to the early presence of central sensitization (CS). Multiple measures are suggested to assess clinical features of CS, yet no ... ...

    Abstract Background and objective: Chronic pain following musculoskeletal trauma is common, which may partially be attributed to the early presence of central sensitization (CS). Multiple measures are suggested to assess clinical features of CS, yet no systematic review has evaluated the measurement properties of these measures in a musculoskeletal trauma population.
    Databases and data treatment: This systematic review, which followed a published and PROSPERO registered protocol (CRD42018091531), aimed to establish the scope of CS measures used within a musculoskeletal trauma population and evaluate their measurement properties. Searches were conducted in two stages by two independent reviewers. The Consensus-based Standards for the selection of Health Measurement Instruments (COSMIN) checklist was used to evaluate risk of bias and overall quality was assessed using the modified Grading of Recommendations Assessment, Development and Evaluation.
    Results: From 86 studies, 30 different CS outcome measures were identified. Nine studies evaluated measurement properties of nine outcome measures; eight evaluated reliability and one evaluated construct validity. Measures included seven quantitative sensory testing methods (pressure, cold and electrical pain thresholds; warm, cold and vibration detection thresholds; vibration perception thresholds), pain drawings and a pinwheel. Risk of bias was assessed as doubtful/inadequate for all but one study, overall quality of evidence was low/very low for all measures. Reliability of measures ranged from poor to excellent.
    Conclusions: Many measures are used to evaluate CS but with limited established measurement properties in musculoskeletal trauma. High quality research to establish measurement properties of CS outcome measures is required.
    Mesh-Begriff(e) Central Nervous System Sensitization ; Checklist ; Chronic Pain ; Humans ; Musculoskeletal Diseases ; Reproducibility of Results
    Sprache Englisch
    Erscheinungsdatum 2020-10-27
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
    ZDB-ID 1390424-3
    ISSN 1532-2149 ; 1090-3801
    ISSN (online) 1532-2149
    ISSN 1090-3801
    DOI 10.1002/ejp.1670
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  6. Artikel ; Online: Classifying individuals with and without patellofemoral pain syndrome using ground force profiles - Development of a method using functional data boosting.

    Liew, Bernard X W / Rugamer, David / Abichandani, Deepa / De Nunzio, Alessandro Marco

    Gait & posture

    2020  Band 80, Seite(n) 90–95

    Abstract: Background: Predictors of recovery in patellofemoral pain syndrome (PFPS) currently used in prognostic models are scalar in nature, despite many physiological measures originally lying on the functional scale. Traditional modelling techniques cannot ... ...

    Abstract Background: Predictors of recovery in patellofemoral pain syndrome (PFPS) currently used in prognostic models are scalar in nature, despite many physiological measures originally lying on the functional scale. Traditional modelling techniques cannot harness the potential predictive value of functional physiological variables.
    Research question: What is the classification performance of PFPS status of a statistical model when using functional ground reaction force (GRF) time-series?
    Methods: Thirty-one individuals (control = 17, PFPS = 14) performed maximal countermovement jumps, on two force plates. The three-dimensional components of the GRF profiles were time-normalized between the start of the eccentric phase and take-off, and used as functional predictors. A statistical model was developed using functional data boosting (FDboost), for binary classification of PFPS statuses (control vs PFPS). The area under the Receiver Operating Characteristic curve (AUC) was used to quantify the model's ability to discriminate the two groups.
    Results: The three predictors of GRF waveform achieved an average out-of-bag AUC of 93.7 %. A 1 % increase in applied medial force reduced the log odds of being in the PFPS group by 0.68 at 87 % of jump cycle. In the AP direction, a 1 % reduction in applied posterior force increased the log odds of being classified as PFPS by 1.10 at 70 % jump cycle. For the vertical GRF, a 1 % increase in applied force reduced the log odds of being classified in the PFPS group by 0.12 at 44 % of the jump cycle.
    Significance: Using simple functional GRF variables collected during functionally relevant task, in conjunction with FDboost, produced clinically interpretable models that retain excellent classification performance in individuals with PFPS. FDboost may be an invaluable tool to be used in longitudinal cohort prognostic studies, especially when scalar and functional predictors are collected.
    Mesh-Begriff(e) Adult ; Case-Control Studies ; Exercise Test ; Female ; Humans ; Patellofemoral Pain Syndrome/classification ; Patellofemoral Pain Syndrome/diagnosis ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-05-25
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2020.05.034
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Can People with Chronic Neck Pain Recognize Their Own Digital Pain Drawing?

    Abichandani, Deepa / Barbero, Marco / Cescon, Corrado / Gallace, Alberto / Punt, David / Sanchis-Sanchez, Enrique / Falla, Deborah

    Pain physician

    2020  Band 23, Heft 2, Seite(n) E231–E240

    Abstract: Background: Although the reliability of pain drawings (PDs) has been confirmed in people with chronic pain, there is a lack of evidence about the validity of the PD, that is, does the PD accurately represent the pain experience of the patient?: ... ...

    Abstract Background: Although the reliability of pain drawings (PDs) has been confirmed in people with chronic pain, there is a lack of evidence about the validity of the PD, that is, does the PD accurately represent the pain experience of the patient?
    Objectives: We investigate whether people with chronic neck pain (CNP) can recognize their own PD to support the validity of the PD in reporting the experience of pain. Moreover, we examined the association between their ability to recognize their own PD with their levels of pain intensity and disability and extent of psychosocial and somatic features.
    Study design: Experimental.
    Setting: University Laboratory.
    Methods: Individuals with CNP completed their PD on a digital body chart, which was then automatically modified with specific dimensions using a novel software, providing an objective range of distortion and eliminating errors, which could potentially occur in manually controlled visual-subjective based methods. Following a 10-minute break listening to music, a series of 20 PDs were presented to each patient in a random order, with only 2 being their original PD. For each PD, the patients rated its likeliness to their own original PD on a scale from 0 to 100, with 100 representing "this is my pain."
    Results: Overall, the patients rated their original PD with a median score of 92% similarity, followed by 91.8% and 89.5% similarity when presented with a PD scaled down to 75% and scaled up by 150% of the original size, respectively; these scores were not significantly different to the ratings given for their original PD. The PD with horizontal translation by 40 pixels (8%) and vertical translation by 70 pixels (12.8%) were rated as the most dissimilar to their original PD; these scores were significantly different to their original PD scores. The Spearman correlation coefficient revealed a significant negative association between their ability to recognize their original PD and their Modified Somatic Perceptions Questionnaire scores.
    Limitations: The patients in the study presented with relatively mild CNP, and the results may not be generalized to those with more severe symptoms.
    Conclusions: People with CNP are generally able to identify their own PD but that their ability to recognize their original PD is negatively correlated with the extent of somatic awareness.
    Key words: Chronic pain, perception, pain drawings, somatic awareness.
    Mesh-Begriff(e) Adult ; Chronic Pain/diagnosis ; Chronic Pain/psychology ; Female ; Humans ; Neck Pain/diagnosis ; Neck Pain/psychology ; Pain Measurement/methods ; Pain Measurement/psychology ; Recognition, Psychology/physiology ; Reproducibility of Results ; Surveys and Questionnaires ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-03-25
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2146393-1
    ISSN 2150-1149 ; 1533-3159
    ISSN (online) 2150-1149
    ISSN 1533-3159
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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