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Article ; Online: Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Brennan Olson / Xinxia Zhu / Mason A. Norgard / Peter R. Levasseur / John T. Butler / Abigail Buenafe / Kevin G. Burfeind / Katherine A. Michaelis / Katherine R. Pelz / Heike Mendez / Jared Edwards / Stephanie M. Krasnow / Aaron J. Grossberg / Daniel L. Marks

Nature Communications, Vol 12, Iss 1, Pp 1-

2021  Volume 15

Abstract: Lipocalin 2 (LCN2) has been recently identified as an endogenous regulator of appetite. Here, using pancreatic cancer as a model of cachexia, the authors demonstrate that LCN2 is a critical mediator of cancer-associated anorexia and may be ... ...

Abstract Lipocalin 2 (LCN2) has been recently identified as an endogenous regulator of appetite. Here, using pancreatic cancer as a model of cachexia, the authors demonstrate that LCN2 is a critical mediator of cancer-associated anorexia and may be therapeutically targeted to improve patient outcomes.
Keywords Science ; Q
Language English
Publishing date 2021-04-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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