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Article: Linear arrector pili muscle hamartoma on the tail of a sphynx cat

Fanton, Natalia / Orlandi, Margherita / Abramo, Francesca

Veterinary dermatology. 2021 Aug., v. 32, no. 4

2021

Abstract: Arrector pili muscle (APM) hamartoma is reported in humans and dogs. We describe a linear APM hamartoma in a sphynx cat. The lesion was characterized by multiple nodules distributed linearly along the tail, made of randomly arranged hypertrophic smooth ... ...

Abstract	Arrector pili muscle (APM) hamartoma is reported in humans and dogs. We describe a linear APM hamartoma in a sphynx cat. The lesion was characterized by multiple nodules distributed linearly along the tail, made of randomly arranged hypertrophic smooth muscles, the size of which tended to wax‐and‐wane during a one year follow‐up.
Keywords	hamartoma ; muscles ; tail ; veterinary medicine
Language	English
Dates of publication	2021-08
Size	p. 395-397.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	Case Reports
ZDB-ID	2011122-8
ISSN	1365-3164 ; 0959-4493
ISSN (online)	1365-3164
ISSN	0959-4493
DOI	10.1111/vde.12962
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Auricular Non-Epithelial Tumors with Solar Elastosis in Cats: A Possible UV-Induced Pathogenesis.

Millanta, Francesca / Parisi, Francesca / Poli, Alessandro / Sorelli, Virginia / Abramo, Francesca

Veterinary sciences

2022 Volume 9, Issue 2

Abstract: The photoinduced etiopathology of actinic keratosis and squamous cell carcinoma in feline species is well known. This etiology has also been reported for non-epithelial cutaneous tumors in other species. To date, no cases of auricular non-epithelial ... ...

Abstract	The photoinduced etiopathology of actinic keratosis and squamous cell carcinoma in feline species is well known. This etiology has also been reported for non-epithelial cutaneous tumors in other species. To date, no cases of auricular non-epithelial cutaneous neoplasms erased in a contest of actinic keratosis in cats have been reported. The aim of this study was to describe feline auricular non-epithelial cutaneous neoplasms associated with typical UV-induced cutaneous lesions and solar elastosis. The study was conducted on five feline cases diagnosed with auricular non-epithelial cutaneous tumors (two fibrosarcomas, one mixosarcoma, one epithelioid melanoma and one hemangiosarcoma), selected from the Tumor Registry of the Department of Veterinary Sciences of the University of Pisa (1998-2018). Ten and six feline auricular biopsies of normal skin and skin with actinic keratosis, respectively, were used as controls. Orcein stain was used to investigate solar elastosis. Histological changes related to chronic solar irradiation were documented in the skin adjacent to the neoplastic lesions in the five cats. Considering the anatomical localization and the results of histopathology, this study suggests that non-epithelial cutaneous neoplasms may have a UV-induced etiopathogenesis in the feline species.
Language	English
Publishing date	2022-01-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2768971-2
ISSN	2306-7381 ; 2306-7381
ISSN (online)	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci9020034
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Article ; Online: Skin Photodamage Lesions in a Bilateral Feline Auricular Primary Fibrosarcoma.

Parisi, Francesca / Abramo, Francesca / Maimone, Marco / Poli, Alessandro / Millanta, Francesca

Veterinary sciences

2022 Volume 9, Issue 10

Abstract: As with human species, recent studies also suggest a photoinduced etiopathology for non-epithelial cutaneous tumors in feline species. We report a recent case of a ten-year-old male cat with a white-hair coat and mesenchymal neoplasms of both auricles. ... ...

Abstract	As with human species, recent studies also suggest a photoinduced etiopathology for non-epithelial cutaneous tumors in feline species. We report a recent case of a ten-year-old male cat with a white-hair coat and mesenchymal neoplasms of both auricles. Cytology, complete blood count (CBC), serum biochemistry and imaging examinations were performed. After surgery, the samples underwent routinary histopathology and were additionally stained with orcein. A routine analysis yielded values within a normal range and the imaging examination showed no abnormalities, suggesting that the bilateral presentation of neoplasms was primary rather than metastatic. The cytology was inconclusive, but, through histopathology, two well-differentiated fibrosarcomas were diagnosed and histopathological changes related to chronic UV exposure (such as epidermal hyperplasia, stratification disorders, keratinocyte dysplasia and an accumulation of elastotic material) were documented in the skin adjacent to the lesions. An orcein stain succeeded in highlighting elastosis. The elastic fibers lost their regular structure and orientation and appeared to be fragmented, wavy to branched and knotted. A morphometric analysis showed that the amount of elastotic material in the dermis close to the tumors was more than double compared with the more distant areas. Elastosis is considered to be a hallmark of photodamage; thus, an involvement of UV rays in the carcinogenic process of the tumors may be suspected.
Language	English
Publishing date	2022-10-05
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2768971-2
ISSN	2306-7381 ; 2306-7381
ISSN (online)	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci9100548
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Article ; Online: Eumycetoma Caused by

Orlandi, Margherita / Giglia, Giuseppe / Danesi, Patrizia / Laricchiuta, Piero / Abramo, Francesca

Journal of fungi (Basel, Switzerland)

2022 Volume 8, Issue 12

Abstract: A captive-kept adult male tiger presented with a large cutaneous and subcutaneous mass on the thigh with a fistula. During sedation, multiple nodules were detected and samples for a histopathological exam were collected. Histologically, granulomatous ... ...

Abstract	A captive-kept adult male tiger presented with a large cutaneous and subcutaneous mass on the thigh with a fistula. During sedation, multiple nodules were detected and samples for a histopathological exam were collected. Histologically, granulomatous panniculitis and dermatitis were seen around dense aggregates of pigmented fungal hyphae, and a diagnosis of phaeohyphomycosis was made; considering the clinical features, it was classified as a eumycotic mycetoma. This is a rarely reported subcutaneous fungal infection in humans and animals, caused by dematiaceous fungi. Clinically, it is characterized by tumefaction, fistulous sinus tracts, and the formation of macroscopically visible grains. In the literature, only a few infections in wild felids have been reported. In this case, Fontana-Masson staining better showed pigmentation and panfungal PCR and sequencing identified
Language	English
Publishing date	2022-12-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2784229-0
ISSN	2309-608X ; 2309-608X
ISSN (online)	2309-608X
ISSN	2309-608X
DOI	10.3390/jof8121289
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Article ; Online: Serum protein electrophoresis in 26 dogs with chronic hepatitis.

Gori, Eleonora / Pierini, Alessio / Tulone, Fiorenza / Abramo, Francesca / Marchetti, Veronica

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

2022 Volume 34, Issue 4, Page(s) 738–741

Abstract: Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was ...

Abstract	Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was to describe SPE alterations in canine CH, to compare SPE results to histologic scores, and to study SPE trends during follow-up. We reviewed retrospectively case data from dogs with a histologic diagnosis of CH. Only cases with SPE, CBC, and serum chemistry results available were included. Dogs were divided into subgroups based on histologic necroinflammatory activity (A) and fibrosis (F) scores (groups A0-1 and A>1; groups F<2 and F≥2). We included 26 dogs; 15 had follow-up SPE. The most common SPE alterations at admission were hypoalbuminemia (
MeSH term(s)	Animals ; Blood Proteins/analysis ; Dog Diseases/diagnosis ; Dogs ; Electrophoresis/veterinary ; Globulins ; Hepatitis, Chronic/diagnosis ; Hepatitis, Chronic/veterinary ; Retrospective Studies ; gamma-Globulins
Chemical Substances	Blood Proteins ; Globulins ; gamma-Globulins
Language	English
Publishing date	2022-06-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	287603-6
ISSN	1943-4936 ; 1040-6387
ISSN (online)	1943-4936
ISSN	1040-6387
DOI	10.1177/10406387221101547
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Linear arrector pili muscle hamartoma on the tail of a sphynx cat.

Fanton, Natalia / Orlandi, Margherita / Abramo, Francesca

Veterinary dermatology

2021 Volume 32, Issue 4, Page(s) 395–397

Abstract	Arrector pili muscle (APM) hamartoma is reported in humans and dogs. We describe a linear APM hamartoma in a sphynx cat. The lesion was characterized by multiple nodules distributed linearly along the tail, made of randomly arranged hypertrophic smooth muscles, the size of which tended to wax-and-wane during a one year follow-up.
MeSH term(s)	Animals ; Cat Diseases/diagnosis ; Cats ; Dog Diseases/diagnosis ; Dogs ; Hair ; Hair Follicle ; Hamartoma/diagnosis ; Hamartoma/veterinary ; Muscle, Smooth
Language	English
Publishing date	2021-04-23
Publishing country	England
Document type	Case Reports
ZDB-ID	2011122-8
ISSN	1365-3164 ; 0959-4493
ISSN (online)	1365-3164
ISSN	0959-4493
DOI	10.1111/vde.12962
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Auricular Non-Epithelial Tumors with Solar Elastosis in Cats: A Possible UV-Induced Pathogenesis

Millanta, Francesca / Parisi, Francesca / Poli, Alessandro / Sorelli, Virginia / Abramo, Francesca

Veterinary sciences. 2022 Jan. 18, v. 9, no. 2

2022

Abstract	The photoinduced etiopathology of actinic keratosis and squamous cell carcinoma in feline species is well known. This etiology has also been reported for non-epithelial cutaneous tumors in other species. To date, no cases of auricular non-epithelial cutaneous neoplasms erased in a contest of actinic keratosis in cats have been reported. The aim of this study was to describe feline auricular non-epithelial cutaneous neoplasms associated with typical UV-induced cutaneous lesions and solar elastosis. The study was conducted on five feline cases diagnosed with auricular non-epithelial cutaneous tumors (two fibrosarcomas, one mixosarcoma, one epithelioid melanoma and one hemangiosarcoma), selected from the Tumor Registry of the Department of Veterinary Sciences of the University of Pisa (1998–2018). Ten and six feline auricular biopsies of normal skin and skin with actinic keratosis, respectively, were used as controls. Orcein stain was used to investigate solar elastosis. Histological changes related to chronic solar irradiation were documented in the skin adjacent to the neoplastic lesions in the five cats. Considering the anatomical localization and the results of histopathology, this study suggests that non-epithelial cutaneous neoplasms may have a UV-induced etiopathogenesis in the feline species.
Keywords	cats ; etiology ; fibrosarcoma ; hemangiosarcoma ; histology ; histopathology ; hyperkeratosis ; melanoma ; pathogenesis ; solar radiation ; squamous cell carcinoma
Language	English
Dates of publication	2022-0118
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2768971-2
ISSN	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci9020034
Database	NAL-Catalogue (AGRICOLA)

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Article: Serum protein electrophoresis in 26 dogs with chronic hepatitis

Gori, Eleonora / Pierini, Alessio / Tulone, Fiorenza / Abramo, Francesca / Marchetti, Veronica

Journal of veterinary diagnostic investigation. 2022 July, v. 34, no. 4

2022

Abstract	Serum protein electrophoresis (SPE) shows the distribution of protein fractions, helping clinicians to characterize some pathologic processes. Information is lacking in the literature about SPE alterations in dogs with chronic hepatitis (CH). Our aim was to describe SPE alterations in canine CH, to compare SPE results to histologic scores, and to study SPE trends during follow-up. We reviewed retrospectively case data from dogs with a histologic diagnosis of CH. Only cases with SPE, CBC, and serum chemistry results available were included. Dogs were divided into subgroups based on histologic necroinflammatory activity (A) and fibrosis (F) scores (groups A0-1 and A>1; groups F<2 and F≥2). We included 26 dogs; 15 had follow-up SPE. The most common SPE alterations at admission were hypoalbuminemia (n = 16), increases in α1-globulins (n = 11), γ-globulins (n = 11), α2-globulins (n = 8), β2-globulins (n = 7), and β1-globulins (n = 6), and decreased albumin:globulin (A:G) ratios (n = 20). Four of 11 dogs had β-γ bridging. Groups with higher A and F scores had higher β2-globulins. Eleven of 15 dogs with a post-treatment SPE had a decrease in γ-globulins and increase in A:G ratio compared to their T0, although there was no statistically significant difference. Although further studies are warranted, SPE may be useful for monitoring canine CH.
Keywords	chronic hepatitis ; dogs ; electrophoresis ; fibrosis ; histology ; hypoalbuminemia
Language	English
Dates of publication	2022-07
Size	p. 738-741.
Publishing place	SAGE Publications
Document type	Article
ZDB-ID	287603-6
ISSN	1943-4936 ; 1040-6387
ISSN (online)	1943-4936
ISSN	1040-6387
DOI	10.1177/10406387221101547
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 3645: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Clinical, histopathological, and molecular characterization of canine pigmented viral plaques.

Orlandi, Margherita / Mazzei, Maurizio / Albanese, Francesco / Pazzini, Luca / Mei, Martina / Lazzarini, Giulia / Forzan, Mario / Massaro, Maria / Vascellari, Marta / Abramo, Francesca

Veterinary pathology

2023 Volume 60, Issue 6, Page(s) 857–864

Abstract: Canine pigmented viral plaques (PVPs) are proliferative epidermal lesions caused by canine papillomaviruses (CPVs). Although the lesions are benign, neoplastic transformation has been reported. Cases reported in the literature are few and mainly focused ... ...

Abstract	Canine pigmented viral plaques (PVPs) are proliferative epidermal lesions caused by canine papillomaviruses (CPVs). Although the lesions are benign, neoplastic transformation has been reported. Cases reported in the literature are few and mainly focused on genome sequencing. The aim of this study was to collect data on the epidemiology, clinicopathological features, and genotyping of PVPs. Fifty-five canine PVPs were retrospectively retrieved and histologically evaluated. Follow-up was available for 33 cases. The median age was 6.5 years and pugs were the most represented breed (25%). There were 4 clinical presentations: a single lesion (24%), multiple lesions (75%) in one (41%) or different sites (34%), and generalized lesions all over the body (24%). The abdomen and axillae were the most common sites. In single lesions, no recurrence was observed after conventional surgery, whereas different medical treatments reported for multiple lesions were not successful. Spontaneous regression was reported in 3 cases. Neoplasia in contiguity with PVPs was seen in 5 of 55 lesions (9%), and 1 dog was euthanized due to invasive squamous cell carcinoma (SCC). The most useful histopathological features for diagnosis were scalloped profile, epidermal spikes, hypergranulosis, and hyperpigmentation. L1 immunolabeling was present in 14 of 16 cases (87%). Sequencing revealed that 10 of 16 cases were associated with CPV-9 (71%), 2 cases were associated with CPV-4 (14%), and 2 cases were associated with CPV-8 (14%). In conclusion, this represents a large cohort study on canine PVPs reporting data on clinicopathological features, therapy, outcome, and the type of CPV involved for the first time in Italy.
MeSH term(s)	Humans ; Dogs ; Animals ; Retrospective Studies ; Cohort Studies ; Dog Diseases/diagnosis ; Dog Diseases/epidemiology ; Dog Diseases/pathology ; Papillomavirus Infections/epidemiology ; Papillomavirus Infections/veterinary ; Papillomavirus Infections/pathology ; Carcinoma, Squamous Cell/veterinary ; Parvovirus, Canine ; Parvoviridae Infections/veterinary
Language	English
Publishing date	2023-08-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	188012-3
ISSN	1544-2217 ; 0300-9858
ISSN (online)	1544-2217
ISSN	0300-9858
DOI	10.1177/03009858231195762
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Dermoscopic findings and comparison of usefulness of longitudinal versus transversal sections in the histological diagnosis of alopecia X.

Zanna, Giordana / Abramo, Francesca / Contiero, Barbara / Zini, Eric / Albanese, Francesco / Borio, Elena / Godizzi, Francesco / Necci, Fabiano / Luciani, Luca / Roccabianca, Paola

Veterinary dermatology

2023 Volume 35, Issue 2, Page(s) 126–137

Abstract: Background: A combination of dermoscopic and histological findings may provide useful information for the diagnosis of hair follicle diseases. However, there are no studies on dermoscopic-histopathological correlations in dogs affected by alopecia X, ... ...

Abstract	Background: A combination of dermoscopic and histological findings may provide useful information for the diagnosis of hair follicle diseases. However, there are no studies on dermoscopic-histopathological correlations in dogs affected by alopecia X, and comparison of longitudinal versus transversal sectioning of skin biopsy specimens in the assessment of this hair loss disorder has not been thoroughly investigated. Hypothesis/objectives: The aim of this study was to correlate dermoscopic and histological features using both longitudinal and transversal sectioning of skin biopsy samples to gain additional information for the diagnosis of alopecia X. Animals: Nineteen Pomeranian dogs affected by alopecia X and five healthy Pomeranians as controls. Materials and methods: Dermoscopic-histological correlation was performed within the diseased group, whereas histological comparisons against controls. The demographic and clinical characteristics also were related to the histological findings. Results: The dermoscopic findings revealed scattered, thinned, short hairs mixed with amorphous keratoseborrhoeic-like material (follicular plugging), perifollicular and intrafollicular scaling, and hyperpigmentation varying from pinpoint black spots to a diffuse texture. Dermoscopic findings correlated with histological findings for selected qualitative and quantitative findings. The usefulness of transversal sections was demonstrated in accurately determining the hair follicular density and counts, growth arrest phases and in identifying mineralisation of hair follicle basement membrane when compared to the longitudinal. Conversely, no correlations between histological findings and demographic and clinical characteristics were detected. Conclusions and clinical relevance: These data provide evidence of the usefulness of dermoscopic evaluation as an accessory diagnostic tool and of transversal sections of skin biopsies as complementary to the diagnosis of alopecia X.
MeSH term(s)	Animals ; Dogs ; Alopecia/diagnosis ; Alopecia/veterinary ; Alopecia/pathology ; Hair/pathology ; Hair Follicle/diagnostic imaging ; Hair Follicle/pathology ; Skin/pathology ; Darier Disease/pathology ; Darier Disease/veterinary
Language	English
Publishing date	2023-10-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2011122-8
ISSN	1365-3164 ; 0959-4493
ISSN (online)	1365-3164
ISSN	0959-4493
DOI	10.1111/vde.13212
Database	MEDical Literature Analysis and Retrieval System OnLINE

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