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  1. Article: The next generation of malaria treatments: the great expectations.

    Abumsimir, Berjas / Al-Qaisi, Talal S

    Future science OA

    2023  Volume 9, Issue 2, Page(s) FSO834

    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Editorial
    ISSN 2056-5623
    ISSN 2056-5623
    DOI 10.2144/fsoa-2023-0018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Vaccination strategies, the power of the unmatched double hits.

    Al-Qaisi, Talal S / Abumsimir, Berjas

    Future science OA

    2023  Volume 9, Issue 9, Page(s) FSO887

    Language English
    Publishing date 2023-07-06
    Publishing country England
    Document type Journal Article
    ISSN 2056-5623
    ISSN 2056-5623
    DOI 10.2144/fsoa-2023-0090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Rereading the genetic origin of cancer: the puzzle of all eras.

    Abumsimir, Berjas / Al-Qaisi, Talal S / Kasmi, Yassine

    Future science OA

    2022  Volume 8, Issue 5, Page(s) FSO799

    Language English
    Publishing date 2022-05-12
    Publishing country England
    Document type Editorial
    ISSN 2056-5623
    ISSN 2056-5623
    DOI 10.2144/fsoa-2022-0014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Suggested parameters to setup Y chromosome microsatellites markers as prostate cancer genetic risk indicator.

    Abumsimir, Berjas / Ennaji, Moulay Mustapha

    Future oncology (London, England)

    2019  Volume 15, Issue 24, Page(s) 2791–2794

    MeSH term(s) Chromosomes, Human, Y/genetics ; Genetic Predisposition to Disease/genetics ; Humans ; Male ; Microsatellite Repeats/genetics ; Prostatic Neoplasms/genetics ; Risk
    Language English
    Publishing date 2019-08-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2019-0197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Helicobacter pylori

    Rihane, Fatima Ezzahra / Erguibi, Driss / Elyamine, Othmane / Abumsimir, Berjas / Ennaji, Moulay Mustapha / Chehab, Farid

    Annals of medicine and surgery (2012)

    2021  Volume 68, Page(s) 102651

    Abstract: Background: Gastric cancer (GC) is one of the leading causes of morbidity and mortality worldwide. The onset and progression of gastric cancer are attributed to numerous triggers, these triggers may be infection of the gastric epithelium by : Methods!# ...

    Abstract Background: Gastric cancer (GC) is one of the leading causes of morbidity and mortality worldwide. The onset and progression of gastric cancer are attributed to numerous triggers, these triggers may be infection of the gastric epithelium by
    Methods: In this study, 100 gastric tissue samples from patients with gastric cancer were examined for detection of
    Results: Results revealed an individual Epstein-Barr virus (EBV) infection observed in (40 %) of gastric carcinoma cases. Furthermore, the frequency of EBV infection was significantly different with intestinal and diffuse gastric cancer types [15 % vs. 85 %; <0.05]. The prevalence of individual
    Conclusion: Thus understanding the status of co-infection could clarify the process of gastric carcinogenesis, and application of this knowledge for clinical purposes could facilitate diagnosis, risk management, and prevention.
    Language English
    Publishing date 2021-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2021.102651
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Germline mutations of B-Raf proto-oncogene and pathological implications in prostate cancer: observational study.

    Tiabi, Ikram / Ennaji, Youssef / Abumsimir, Berjas / Laraqui, Abdelilah / Ennibi, Khalid / Mrabti, Mohammed / Alami, Mohammed / Mahasneh, Ihsan Ali / Benchekroun, Mohammed Nabil / Ennaji, Moulay Mustapha

    Annals of medicine and surgery (2012)

    2023  Volume 85, Issue 6, Page(s) 2628–2634

    Abstract: B-Raf proto-oncogene has been found in a variety of neoplasms. BRAF stimulation can promote tumour proliferation through the activation of the MAP/ERK kinase pathway. This study aimed to determine the germline spectra of BRAF and the association with ... ...

    Abstract B-Raf proto-oncogene has been found in a variety of neoplasms. BRAF stimulation can promote tumour proliferation through the activation of the MAP/ERK kinase pathway. This study aimed to determine the germline spectra of BRAF and the association with pathological criteria of prostate tumours.
    Methods: Fifty blood samples from men treated with prostate cancer were analyzed for BRAF germline mutations and confirmed by Sanger sequencing, in addition, to establishing the frequencies and clinical correlations of frequent mutations in the BRAF gene for both exon 11 and exon 15. The frequency and distribution of high-frequency mutations were analyzed according to the pathological criteria of the patients.
    Results: Frameshift mutations: c.1628_1629insA and c.1624_1625insT with a frequency of (46%) and (18%), respectively, Nonsense mutations: c.1181C>A (p.Ser394Ter) was detected in one patient, missense mutations: c.1226A>G (p.Gln409Arg), c.1270T>C (p.Trp424Arg), c.1270_1271delins2 (p.Trp424Leu), with a frequency of (4%) were detected. There was no significant difference between mutation carriers and non-carriers regarding medical and surgical history, but prostate-specific antigen concentration was significantly different between the two groups.
    Conclusion: The results of this study elucidate the presence and involvement of germline mutations in prostate cancer, which could serve as a potential indicator for the diagnosis and therapeutic management of prostate cancer in the population studied.
    Language English
    Publishing date 2023-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000000685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Molecular characterization of human papillomavirus and mouse mammary tumor virus-

    Abumsimir, Berjas / Mrabti, Mohammed / Laraqui, Abdelilah / Ameur, Ahmed / Koraishi, Saad Ibnsouda / Mzibri, Mohammed / Lamsisi, Maryame / Ennaji, Youssef / Almahasneh, Ihsan / Ennaji, Moulay Mustapha

    Molecular and clinical oncology

    2022  Volume 16, Issue 5, Page(s) 97

    Abstract: The suspected roles of human Papillomavirus (HPV) and mouse mammary tumor virus (MMTV) infections in prostate tumor development were recently reported. To detect the frequency of HPV and MMTV- ...

    Abstract The suspected roles of human Papillomavirus (HPV) and mouse mammary tumor virus (MMTV) infections in prostate tumor development were recently reported. To detect the frequency of HPV and MMTV-
    Language English
    Publishing date 2022-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2796865-0
    ISSN 2049-9469 ; 2049-9450
    ISSN (online) 2049-9469
    ISSN 2049-9450
    DOI 10.3892/mco.2022.2530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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