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  1. Article ; Online: Letter: Multiple Factors Could Affect Blood Pressure in Patients With COVID-19.

    Açar, Burak

    Angiology

    2022  Volume 73, Issue 7, Page(s) 688

    MeSH term(s) Angiotensin-Converting Enzyme Inhibitors ; Blood Pressure ; COVID-19 ; Humans ; Hypertension
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors
    Language English
    Publishing date 2022-03-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80040-5
    ISSN 1940-1574 ; 0003-3197
    ISSN (online) 1940-1574
    ISSN 0003-3197
    DOI 10.1177/00033197221082335
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  2. Article ; Online: The effect of adjuvant Mitomycin C during vitrectomy on functional and anatomical outcomes in patients with severe diabetic tractional retinal detachment.

    Gurelik, Ihsan Gokhan / Ozdemir, Huseyin Baran / Acar, Burak

    International ophthalmology

    2024  Volume 44, Issue 1, Page(s) 210

    Abstract: Purpose: To evaluate the effect of adjuvant Mitomycin C (MMC) use on the anatomical and functional success of vitreoretinal surgery (VRS) in severe diabetic tractional retinal detachment (dTRD) patients.: Methods: A retrospective analysis of ... ...

    Abstract Purpose: To evaluate the effect of adjuvant Mitomycin C (MMC) use on the anatomical and functional success of vitreoretinal surgery (VRS) in severe diabetic tractional retinal detachment (dTRD) patients.
    Methods: A retrospective analysis of consecutive patients undergoing VRS due to severe dTRD was conducted. Patients were categorized into those who received 20 µg/0.1 mL MMC via MMC sandwich method (Group 1) and those who did not (Group 2). Demographics, surgical characteristics, visual outcomes, and complications that may related to MMC were analyzed.
    Results: A total of 25 eyes were included, 13 in Group 1 and 12 in Group 2. No statistical difference was observed in baseline characteristics between the groups. The mean best-corrected visual acuity was 1.90 ± 0.43 logMAR and 1.93 ± 0.41 logMAR preoperatively and 1.60 ± 0.78 logMAR and 1.56 ± 0.78 logMAR postoperatively in Groups 1 and 2, respectively (p = 0.154). The postoperative mean intraocular pressure was 16.23 ± 2.55 mmHg and 13.08 ± 4.94 mmHg in Groups 1 and 2, respectively (p = 0.225). The rate of re-surgery was significantly lower in Group 1 (0% vs. 41.7% in Group 2, p = 0.015). Retina was attached in all patients at the last visit. No MMC-related complication was recorded.
    Conclusion: Intraoperative adjuvant MMC application for severe dTRD significantly reduces re-surgery rates with good anatomical and functional outcomes safely.
    MeSH term(s) Humans ; Retrospective Studies ; Male ; Female ; Mitomycin/administration & dosage ; Vitrectomy/methods ; Middle Aged ; Diabetic Retinopathy/complications ; Diabetic Retinopathy/physiopathology ; Diabetic Retinopathy/diagnosis ; Diabetic Retinopathy/surgery ; Retinal Detachment/surgery ; Retinal Detachment/diagnosis ; Visual Acuity ; Aged ; Treatment Outcome ; Chemotherapy, Adjuvant/methods ; Alkylating Agents/administration & dosage ; Follow-Up Studies ; Adult
    Chemical Substances Mitomycin (50SG953SK6) ; Alkylating Agents
    Language English
    Publishing date 2024-05-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-024-03152-3
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  3. Article ; Online: Predictors of the right ventricular perforation caused by active-fixation pacing and defibrillator leads: A single-centre experience.

    Celikyurt, Umut / Acar, Burak / Yavuz, Sadan / Agacdiken, Aysen / Vural, Ahmet

    Journal of cardiovascular electrophysiology

    2024  Volume 35, Issue 3, Page(s) 399–405

    Abstract: Introduction: Active-fixation leads have been associated with higher incidence of cardiac perforation. Large series specifically evaluating radiographic predictors of right ventricular (RV) lead perforation are lacking.: Methods: We conducted a ... ...

    Abstract Introduction: Active-fixation leads have been associated with higher incidence of cardiac perforation. Large series specifically evaluating radiographic predictors of right ventricular (RV) lead perforation are lacking.
    Methods: We conducted a retrospective observational study including 1691 consecutive patients implanted with an active fixation pacing and defibrillator lead at our institution between January 2015 and January 2021. Fourteen patients who had clinically relevant RV perforation caused by pacemaker and implantable cardioverter-defibrillator leads were included in the study.
    Results: Univariate and multivariate analyses were used to identify predictors of RV perforation. In multivariate analysis, lead slack score (odds ratio [OR]: 3.694, 95% confidence interval [CI]: 1.066-12.807; p = .039), change in lead slack height (OR: 1.218, 95% CI: 1.011-1.467; p = .038) and width (OR: 1.253, 95% CI: 1.120-1.402; p = .001), left ventricular ejection fraction (OR: 0.995, 95% CI: 0.910-1.088; p = .032) were independent predictors of RV perforation.
    Conclusion: Fluoroscopic predictors of RV perforation associated with RV lead can be easily determined during implantation. Identification of these predictors may prevent the sequelae of RV perforation associated with active-fixation leads.
    MeSH term(s) Humans ; Stroke Volume ; Ventricular Function, Left ; Pacemaker, Artificial/adverse effects ; Defibrillators, Implantable/adverse effects ; Heart Ventricles/diagnostic imaging ; Retrospective Studies ; Heart Injuries/diagnostic imaging ; Heart Injuries/etiology
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.16181
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  4. Article ; Online: Electrocardiographic Predictors of Complete Heart Block During Right Ventricular Lead Implantation in Patients Who Underwent Cardiac Resynchronization Therapy.

    Celikyurt, Umut / Acar, Burak / Agacdiken, Aysen / Vural, Ahmet

    The American journal of cardiology

    2023  Volume 201, Page(s) 62–67

    Abstract: Cardiac resynchronization therapy (CRT) device procedures have their own complications in addition to the complications associated with standard pacemaker implantations. This study aimed to analyze the predictors of the right bundle branch injury ... ...

    Abstract Cardiac resynchronization therapy (CRT) device procedures have their own complications in addition to the complications associated with standard pacemaker implantations. This study aimed to analyze the predictors of the right bundle branch injury resulting in complete heart block (CHB) during right ventricular (RV) lead implantation in patients who underwent CRT with defibrillator. We conducted an observational study of consecutive 790 patients who underwent CRT with defibrillator device implantation at our institution from 2010 to 2022. Relevant clinical information and complete data regarding the echocardiographic data, implantation procedure, and clinical follow-up were collected into a computerized database. A total of 29 patients (3.7%) had CHB during RV lead implantation. In multivariate analysis, left axis deviation (odds ratio [OR] 2.408, 95% confidence interval [CI] 1.025 to 5.658, p = 0.044), QRS width (OR 1.022, 95% CI 1.001 to 1.043, p = 0.035) and QRS alternans (OR 4.214, 95% CI 1.788 to 9.930, p = 0.001) were found independently related to right bundle branch injury resulting in CHB development during RV lead implantation. In conclusion, left axis deviation, QRS width, and QRS alternans were associated with a higher rate of CHB, and these findings provide insight into optimal and safe CRT device implantation strategies based on preprocedural characteristics.
    MeSH term(s) Humans ; Cardiac Resynchronization Therapy/methods ; Treatment Outcome ; Defibrillators, Implantable ; Electrocardiography ; Heart Block/therapy ; Heart Failure
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2023.05.072
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  5. Article ; Online: Prognostic value of non-alcoholic fatty liver disease fibrosis score in patients undergoing cardiac resynchronization therapy.

    Acar, Burak / Celikyurt, Umut / Agacdiken, Aysen / Vural, Ahmet

    Pacing and clinical electrophysiology : PACE

    2023  Volume 46, Issue 3, Page(s) 251–257

    Abstract: Background: Cardiac resynchronization therapy (CRT) is an effective option in the treatment of patients with heart failure and wide QRS. Non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) has been shown to predict cardiac events in several ... ...

    Abstract Background: Cardiac resynchronization therapy (CRT) is an effective option in the treatment of patients with heart failure and wide QRS. Non-alcoholic fatty liver disease (NAFLD) fibrosis score (NFS) has been shown to predict cardiac events in several patient populations. However, the relationship between NFS and response to CRT has not been investigated. The aim of the study was to investigate the predictive role of NFS in the assessment of response after CRT.
    Methods: Three hundred thirty-six patients with heart failure undergoing CRT were prospectively studied. Liver fibrosis were assessed according to the non-alcoholic fatty liver disease fibrosis score (NFS), which includes age, body mass index, impaired fasting glycemia or diabetes mellitus, aspartate aminotransferase /alanine aminotransferase ratio, platelets, and albumin. Echocardiographic response to CRT was defined by a ≥15% reduction in left ventricular end-systolic volume at six months at follow-up.
    Results: Two hundred thirty-eight patients (71%) had CRT response after 6 months of follow-up. Receiver-operator characteristic curve analysis showed NFS cutoff value of < -1.12 for predicting CRT response with a sensitivity of 70.4% and a specificity of 52.9%. The patients were also divided into four groups according to the quartiles of NFS. The proportion of response to CRT was increased with lower level of NFS value. Multivariate logistic regression analysis demonstrated the NFS score < -1.12 and LVIDs were independent predictors of the CRT response. In the second model of analysis which included NFS, quartiles demonstrated that fourth NFS quartile and LVIDs were independent predictors of CRT response.
    Conclusion: Liver fibrosis assessed by NFS can provide valuable information to predict reverse remodeling in patients undergoing CRT. The present study supports monitoring of NFS to improve preoperative risk stratification of these patients.
    MeSH term(s) Humans ; Prognosis ; Non-alcoholic Fatty Liver Disease/therapy ; Cardiac Resynchronization Therapy ; Liver Cirrhosis/therapy ; Heart Failure/therapy
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14657
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  6. Article: Acute Myocardial Infarction Due to Myocardial Bridge Treated With Surgery: a Case Report.

    Açar, Burak / Torun, Akin / Celikyurt, Umut / Talas, Zeki / Yavuz, Sadan

    Kardiologiia

    2023  Volume 63, Issue 11, Page(s) 96–100

    Abstract: Myocardial bridging is congenital anomaly characterized by segment of epicardial coronary arteries passing through the myocardium. Various ischemic conditions are related with this pathology. We report a case of myocardial bridging that was complicated ... ...

    Abstract Myocardial bridging is congenital anomaly characterized by segment of epicardial coronary arteries passing through the myocardium. Various ischemic conditions are related with this pathology. We report a case of myocardial bridging that was complicated with acute anterior myocardial infarction and a review of the literature. The patient was treated successfully with coronary bypass graft surgery after unsuccessful percutaneous intervention.
    MeSH term(s) Humans ; Coronary Angiography ; Coronary Artery Bypass ; Myocardial Bridging/complications ; Myocardial Bridging/diagnosis ; Myocardial Bridging/surgery ; Myocardial Infarction/diagnosis ; Myocardial Infarction/etiology ; Myocardial Infarction/surgery ; Myocardium/pathology
    Language English
    Publishing date 2023-12-05
    Publishing country Russia (Federation)
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 131029-x
    ISSN 0022-9040
    ISSN 0022-9040
    DOI 10.18087/cardio.2023.11.n2063
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  7. Article ; Online: Comparison of selective coronary angiography through the ablation catheter versus conventional coronary angiography to guide ablation of premature ventricular contractions originating from aortic cusp.

    Celikyurt, Umut / Acar, Burak / Agacdiken, Aysen / Vural, Ahmet

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2022  Volume 65, Issue 3, Page(s) 711–715

    Abstract: Background: Intraprocedural coronary angiography (CA) is recommended in patients undergoing ablation in aortic cusps to assess the relation of catheter tip and coronary ostia. In this report, we aimed to compare selective coronary angiography (SCA) ... ...

    Abstract Background: Intraprocedural coronary angiography (CA) is recommended in patients undergoing ablation in aortic cusps to assess the relation of catheter tip and coronary ostia. In this report, we aimed to compare selective coronary angiography (SCA) through the contact force (CF)-sensing radiofrequency catheter with conventional coronary angiography (CCA) to guide ablation of premature ventricular contractions (PVC).
    Methods: This was a retrospective observational cohort study of prospectively collected data of 87 consecutive patients undergoing PVC ablation at a single institution between February 2016 and June 2021. Forty-six patients (53%) underwent SCA and forty-one patients (47%) underwent CCA. Data were consecutively collected case-by-case and entered into a computerized database. Procedural characteristics, complications, and clinical outcomes were compared between the SCA and CCA groups.
    Results: Successful ablation was achieved in seventy-seven (89%) patients. Total procedure and fluoroscopy time and radiation dose were significantly lower in SCA group (93 ± 22 min vs 102 ± 20 min, p = 0.042; 12 ± 3 min vs 14 ± 4 min, p = 0.030; 3292 ± 1221 μGy m
    Conclusions: Selective coronary angiography through the CF-sensing ablation catheter to assess the relation between the ablation site and the coronary ostia is feasible and safe. This technique precludes the requirement of an additional arterial access and decreases the total procedure and fluoroscopy time and radiation dose.
    MeSH term(s) Humans ; Ventricular Premature Complexes/diagnostic imaging ; Ventricular Premature Complexes/surgery ; Coronary Angiography ; Cohort Studies
    Language English
    Publishing date 2022-08-05
    Publishing country Netherlands
    Document type Observational Study ; Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-022-01324-8
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  8. Article ; Online: Reply to the Letter to the Editor: 'The Qualitative Assessment for Ostial Side Branch Disease in Isolated Non-Left Main Coronary Artery'.

    Torun, Akın / Açar, Burak / Kahraman, Göksel / Ural, Ertan / Kılıç, Teoman / Çelikyurt, Umut / Ağaçdiken Ağır, Ayşen

    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir

    2024  Volume 51, Issue 8, Page(s) 590–591

    Title translation Editöre Mektup Yanıtı: 'Sol Ana Koroner Arter Olmayan İzole Ostial Yan Dal Hastalığının Kalitatif Olarak Değerlendirilmesi'.
    MeSH term(s) Humans ; Coronary Vessels/diagnostic imaging ; Coronary Artery Disease ; Coronary Stenosis
    Language English
    Publishing date 2024-01-02
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1215217-1
    ISSN 1308-4488 ; 1016-5169
    ISSN (online) 1308-4488
    ISSN 1016-5169
    DOI 10.5543/tkda.2023.62763
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  9. Article: Effects of 4-Week Low-Load Resistance Training with Blood Flow Restriction on Muscle Strength and Left Ventricular Function in Young Swimmers: A Pilot Randomized Trial.

    Wang, Zhenhuan / Atakan, Muhammed M / Acar, Burak / Xiong, Rui / Peng, Li

    Journal of human kinetics

    2023  Volume 87, Page(s) 63–76

    Abstract: Low-load resistance training combined with blood flow restriction (BFR) is known to result in muscle hypertrophy and strength similar to that observed with higher loads. However, the effects of resistance training with BFR on cardiac structure and ... ...

    Abstract Low-load resistance training combined with blood flow restriction (BFR) is known to result in muscle hypertrophy and strength similar to that observed with higher loads. However, the effects of resistance training with BFR on cardiac structure and cardiac function remain largely unknown. Therefore, the purpose of this randomized study was to compare the effects of conventional high-load resistance training (HL-RT) with the effects of low-load resistance training with BFR (LL-BFR) on muscle strength and left ventricular function. Sixteen young swimmers (mean ± standard deviation: age = 19.7 ± 1.6 years, body mass = 78.9 ± 9.7 kg, body height = 180.8 ± 5.8 cm) were randomly allocated to a conventional HL-RT group (n = 8) or a LL-BFR group (n = 8) with a pressure band (200 mmHg) placed on both thighs of participants for 4 weeks (3 days•week
    Language English
    Publishing date 2023-07-15
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2503989-1
    ISSN 1899-7562 ; 1640-5544
    ISSN (online) 1899-7562
    ISSN 1640-5544
    DOI 10.5114/jhk/163013
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  10. Article: Stent Implantation May Fail Sometimes in Coronary Complications: Extension of an Iatrogenic Left Main Coronary Artery Hematoma.

    Acar, Burak / Arıkan, Ali Ahmet / Talas, Zeki / Celikyurt, Umut / Kanko, Muhip

    The journal of Tehran Heart Center

    2023  Volume 17, Issue 4, Page(s) 249–251

    Abstract: Coronary artery perforations and dissections, associated with cardiac tamponade or acute vessel closure, are life-threatening complications of percutaneous coronary intervention. In some cases, subepicardial hematomas could occur and compress the vessel. ...

    Abstract Coronary artery perforations and dissections, associated with cardiac tamponade or acute vessel closure, are life-threatening complications of percutaneous coronary intervention. In some cases, subepicardial hematomas could occur and compress the vessel. A 59-year-old woman was admitted to our hospital with chest pain and was diagnosed with non-ST-elevation myocardial infarction. Coronary angiography showed the total occlusion of the diagonal artery. During the intervention, left main coronary artery dissection and intramural hematoma occurred as coronary complications. The left main coronary artery was stented; however, the extension of the hematoma through the ostium of the left anterior descending artery caused further complications. The patient underwent an urgent coronary artery bypass graft surgery and was discharged on the seventh postoperative day.
    Language English
    Publishing date 2023-04-18
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2476998-8
    ISSN 2008-2371 ; 1735-5370 ; 1735-8620
    ISSN (online) 2008-2371
    ISSN 1735-5370 ; 1735-8620
    DOI 10.18502/jthc.v17i4.11615
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