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Article ; Online: Gliflozins and Atrial Fibrillation.

Corbalan, Ramon / Acevedo, Mónica

Journal of the American College of Cardiology

2022 Volume 80, Issue 18, Page(s) 1718–1720

MeSH term(s)	Humans ; Atrial Fibrillation ; Sodium-Glucose Transporter 2 Inhibitors ; Stroke Volume ; Heart Failure ; Prognosis
Chemical Substances	Sodium-Glucose Transporter 2 Inhibitors
Language	English
Publishing date	2022-08-27
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2022.08.746
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Article ; Online: Long-term maternal cardiovascular risk after preeclampsia: a latent vascular enemy.

Acevedo, Monica / Varleta, Paola / Tagle, Rodrigo

Heart (British Cardiac Society)

2023 Volume 109, Issue 6, Page(s) 422–424

MeSH term(s)	Pregnancy ; Female ; Humans ; Pre-Eclampsia ; Cardiovascular Diseases ; Risk Factors ; Heart Disease Risk Factors
Language	English
Publishing date	2023-02-23
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	1303417-0
ISSN	1468-201X ; 1355-6037
ISSN (online)	1468-201X
ISSN	1355-6037
DOI	10.1136/heartjnl-2022-321877
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Article: Sustainability and circularity in fruit and vegetable production. Perceptions and practices of reduction and valorization of agricultural waste biomass in south-eastern Spain

Duque-Acevedo, Mónica / Belmonte-Ureña, Luis J. / Terán-Yépez, Eduardo / Camacho-Ferre, Francisco

Journal of environmental management. 2022 Aug. 15, v. 316

2022

Abstract: This study aims to conduct an exploratory and comparative analysis between Fruit and Vegetable Producer Organizations (FVPOs) and fruit and vegetable producers that are not part of these organizations (Non-FVPOs) regarding the prioritization, perception, ...

Abstract	This study aims to conduct an exploratory and comparative analysis between Fruit and Vegetable Producer Organizations (FVPOs) and fruit and vegetable producers that are not part of these organizations (Non-FVPOs) regarding the prioritization, perception, and adoption of sustainable and circular practices. For this purpose, data was collected from both groups through an online survey. Statistical techniques for the comparison of two independent groups (chi-square test, Fisher's exact test, and Mann-Whitney U test) were used to examine the differences on a sample of 14 FVPOs and 22 Non-FVPOs from Spain. Although the results show more similarities than differences between the two groups, they highlight that FVPOs are more likely to prioritize environmental factors and implement both green manuring and biodegradable raffia as the main Agricultural Waste Biomass (AWB) reduction and/or valorization practices. In addition, the findings point to the relevance of environmental considerations and specifically to the Sustainable and Circular Production Models (SCPMs) as an alternative to the traditional fruit and vegetable production system. Theoretically, the results mainly contradict resource and first mover advantage arguments by revealing that more resourceful organizations do not necessarily possess better environmental management. This study also provides innovative information and relevant contributions for governments. It allows them to identify aspects that should be strengthened in relation to policies, regulatory frameworks, and/or strategies that promote sustainable and circular production systems for both FVPOs and Non-FVPOs. In addition, it contributes with implications, for organizations and farmers, how to improve actions and opportunities to advance the transition to SCPMs.
Keywords	agricultural wastes ; biodegradability ; biomass ; chi-square distribution ; environmental management ; fruits ; prioritization ; surveys ; vegetable growing ; vegetables ; Spain
Language	English
Dates of publication	2022-0815
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2022.115270
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Article ; Online: Sustainability and circularity in fruit and vegetable production. Perceptions and practices of reduction and valorization of agricultural waste biomass in south-eastern Spain.

Duque-Acevedo, Mónica / Belmonte-Ureña, Luis J / Terán-Yépez, Eduardo / Camacho-Ferre, Francisco

Journal of environmental management

2022 Volume 316, Page(s) 115270

Abstract	This study aims to conduct an exploratory and comparative analysis between Fruit and Vegetable Producer Organizations (FVPOs) and fruit and vegetable producers that are not part of these organizations (Non-FVPOs) regarding the prioritization, perception, and adoption of sustainable and circular practices. For this purpose, data was collected from both groups through an online survey. Statistical techniques for the comparison of two independent groups (chi-square test, Fisher's exact test, and Mann-Whitney U test) were used to examine the differences on a sample of 14 FVPOs and 22 Non-FVPOs from Spain. Although the results show more similarities than differences between the two groups, they highlight that FVPOs are more likely to prioritize environmental factors and implement both green manuring and biodegradable raffia as the main Agricultural Waste Biomass (AWB) reduction and/or valorization practices. In addition, the findings point to the relevance of environmental considerations and specifically to the Sustainable and Circular Production Models (SCPMs) as an alternative to the traditional fruit and vegetable production system. Theoretically, the results mainly contradict resource and first mover advantage arguments by revealing that more resourceful organizations do not necessarily possess better environmental management. This study also provides innovative information and relevant contributions for governments. It allows them to identify aspects that should be strengthened in relation to policies, regulatory frameworks, and/or strategies that promote sustainable and circular production systems for both FVPOs and Non-FVPOs. In addition, it contributes with implications, for organizations and farmers, how to improve actions and opportunities to advance the transition to SCPMs.
MeSH term(s)	Agriculture ; Biomass ; Fruit ; Spain ; Vegetables
Language	English
Publishing date	2022-05-19
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2022.115270
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Article ; Online: Management of agricultural waste biomass as raw material for the construction sector: an analysis of sustainable and circular alternatives

Duque-Acevedo, Mónica / Lancellotti, Isabella / Andreola, Fernanda / Barbieri, Luisa / Belmonte-Ureña, Luis J. / Camacho-Ferre, Francisco

Environ Sci Eur. 2022 Dec., v. 34, no. 1 p.70-70

2022

Abstract: BACKGROUND: The agricultural and construction sectors demand enormous amounts of natural resources and generate environmental impacts that negatively affect ecosystems. One of the main problems is the generation and inadequate management of waste. For ... ...

Abstract	BACKGROUND: The agricultural and construction sectors demand enormous amounts of natural resources and generate environmental impacts that negatively affect ecosystems. One of the main problems is the generation and inadequate management of waste. For this reason, under the approaches of the new sustainable and circular models, waste valorization has been prioritised as a strategy for advancing towards the sustainability of production systems. This research aims to carry out a general analysis of Agricultural Waste Biomass (AWB) in the production of bio-based products for the construction sector. Bibliometric techniques were applied for the general analysis of the scientific production obtained from Scopus. A systematic review identified the main research approaches. In addition, European projects were reviewed to assess the practical application. This study is novel and provides relevant contributions to new trends in the valorisation of AWB in the building sector and the sustainability benefits. For policymakers, it is a source of information on the contribution of new policies to scientific advances and the aspects that need to be strengthened to improve sustainable and circular practices in both sectors. RESULTS: The results show that 74% of the research has been published within the last 5 years. Regarding the main types of AWBs, rice husk ash and sugar cane bagasse ash are the most commonly used in manufacturing a wide variety of bio-based building products. Cement, concrete and bricks are the main bio-based products obtained from AWB. However, a new approach to utilisation was identified in road construction. CONCLUSIONS: The findings indicate that the AWB is an important resource with great potential for the construction sector. Similarly, that policies on sustainable and circular development have driven scientific progress on new alternatives for the valorisation of AWB to improve sustainability in the construction sector. Although the practical application has also been driven through European projects, development at this level is still low. Therefore, it is necessary to strengthen partnerships between these two sectors and improve government strategies on sustainability and circularity to overcome existing constraints.
Keywords	agricultural wastes ; biomass ; cement ; concrete ; husk ash ; information sources ; raw materials ; road construction ; sugarcane bagasse ; systematic review ; Europe
Language	English
Dates of publication	2022-12
Size	p. 70.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	2593962-2
ISSN	2190-4715 ; 2190-4707
ISSN (online)	2190-4715
ISSN	2190-4707
DOI	10.1186/s12302-022-00655-7
Database	NAL-Catalogue (AGRICOLA)

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Article: Management of Agricultural Waste Biomass: A case study of Fruit and Vegetable Producer Organizations in southeast Spain

Duque-Acevedo, Mónica / Belmonte-Ureña, Luis J. / Batlles-delaFuente, Ana / Camacho-Ferre, Francisco

Journal of cleaner production. 2022 July 20, v. 359

2022

Abstract: Policies and strategies that encourage the adoption of environmentally friendly practices in the agricultural sector also promote mechanisms that facilitate their implementation. One of them is the creation of Producer Organizations and the granting of ... ...

Abstract	Policies and strategies that encourage the adoption of environmentally friendly practices in the agricultural sector also promote mechanisms that facilitate their implementation. One of them is the creation of Producer Organizations and the granting of subsidies to farmers. Therefore, this study aims to analyse the most relevant aspects of the management of Agricultural Waste Biomass (AWB) by Fruit and Vegetable Producer Organizations (FVPOs) in a province in southeastern Spain. For this purpose, a case study was carried out that included surveys of 14 FVPOs (38% of the total). A descriptive method and a multivariate statistical technique were used to characterise these organizations. The results show that most of the FVPOs implement more than one AWB reduction and/or valorization practice, mainly the use of biodegradable and/or compostable raffia. However, the findings of the cluster analysis show that there are differences in the degree of relevance that the FVPOs give to the reduction and/or valorization of AWB. This exploratory study provides novel and relevant information that contributes to the characterization of the FVPOs and improves the knowledge on their trend in the management of AWB. It also serves as a tool for governments to assess the environmental provisions included in the regulatory framework of FVPOs. From this it will be possible to identify improvement actions to promote AWB valorization practices in the fruit and vegetable sector under the circular economy and bioeconomy approaches.
Keywords	agricultural industry ; agricultural wastes ; biodegradability ; bioeconomics ; biomass ; case studies ; circular economy ; cluster analysis ; fruits ; vegetables ; Spain
Language	English
Dates of publication	2022-0720
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0959-6526
DOI	10.1016/j.jclepro.2022.131972
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Article ; Online: New Mechanisms to Prevent Heart Failure with Preserved Ejection Fraction Using Glucagon-like Peptide-1 Receptor Agonism (GLP-1 RA) in Metabolic Syndrome and in Type 2 Diabetes: A Review.

Jalil, Jorge E / Gabrielli, Luigi / Ocaranza, María Paz / MacNab, Paul / Fernández, Rodrigo / Grassi, Bruno / Jofré, Paulina / Verdejo, Hugo / Acevedo, Monica / Cordova, Samuel / Sanhueza, Luis / Greig, Douglas

International journal of molecular sciences

2024 Volume 25, Issue 8

Abstract: This review examines the impact of obesity on the pathophysiology of heart failure with preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF prevention using a glucagon-like peptide-1 receptor agonism (GLP-1 RA). Obesity can lead ...

Abstract	This review examines the impact of obesity on the pathophysiology of heart failure with preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF prevention using a glucagon-like peptide-1 receptor agonism (GLP-1 RA). Obesity can lead to HFpEF through various mechanisms, including low-grade systemic inflammation, adipocyte dysfunction, accumulation of visceral adipose tissue, and increased pericardial/epicardial adipose tissue (contributing to an increase in myocardial fat content and interstitial fibrosis). Glucagon-like peptide 1 (GLP-1) is an incretin hormone that is released from the enteroendocrine L-cells in the gut. GLP-1 reduces blood glucose levels by stimulating insulin synthesis, suppressing islet α-cell function, and promoting the proliferation and differentiation of β-cells. GLP-1 regulates gastric emptying and appetite, and GLP-1 RA is currently indicated for treating type 2 diabetes (T2D), obesity, and metabolic syndrome (MS). Recent evidence indicates that GLP-1 RA may play a significant role in preventing HFpEF in patients with obesity, MS, or obese T2D. This effect may be due to activating cardioprotective mechanisms (the endogenous counter-regulatory renin angiotensin system and the AMPK/mTOR pathway) and by inhibiting deleterious remodeling mechanisms (the PKA/RhoA/ROCK pathway, aldosterone levels, and microinflammation). However, there is still a need for further research to validate the impact of these mechanisms on humans.
MeSH term(s)	Humans ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/metabolism ; Heart Failure/metabolism ; Heart Failure/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/complications ; Metabolic Syndrome/metabolism ; Metabolic Syndrome/drug therapy ; Stroke Volume/drug effects ; Animals ; Glucagon-Like Peptide 1/metabolism ; Obesity/metabolism ; Obesity/complications ; Obesity/drug therapy
Chemical Substances	Glucagon-Like Peptide-1 Receptor ; Glucagon-Like Peptide 1 (89750-14-1)
Language	English
Publishing date	2024-04-17
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25084407
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Article ; Online: Prevalence and determinants of ideal cardiovascular health in a latin women cohort: a cross-sectional study.

Acevedo, Mónica / Varleta, Paola / Casas-Cordero, Carolina / Berríos, Amalia / Navarrete, Carlos / López, Rosario

Lancet regional health. Americas

2021 Volume 4, Page(s) 100071

Abstract: Background: Ideal cardiovascular health (CVH) sought to reduce cardiovascular (CV) morbidity and mortality. In Chile, CV mortality in women is high. The study's main aim was to determine the prevalence of ideal CVH, and the factors and behaviors ... ...

Abstract	Background: Ideal cardiovascular health (CVH) sought to reduce cardiovascular (CV) morbidity and mortality. In Chile, CV mortality in women is high. The study's main aim was to determine the prevalence of ideal CVH, and the factors and behaviors associated with ideal CVH in women from Santiago de Chile. Methods: Cross-sectional study in women between 35 - 70 years old who were selected through a probabilistic, multistage, and geographically stratified sampling. The study included a survey on demographic and CV risk factors and anthropometric, blood pressure, and biochemical measurements. Three categories were used to characterize low (0-2), intermediate (3-4), and high (5-7) levels of AHA's Ideal CVH index. We assessed the prevalence of ideal CVH by age, education level, and socioeconomic status and determined the independent associations of different variables with ideal CVH. Findings: 620 women, mean age 51± 4 years old, were recruited. Ideal CVH prevalence was 14.3%; none of the women presented an ideal healthy diet, and only 22.6% reached an ideal BMI. The best predictors of ideal CVH were a high education level (OR= 2.85; 1.43 to 5.92; p < 0.01), having less than two alcoholic drinks per day (OR= 4.09; 1.60 to 13.77; p< 0.01), and having a pregnancy history without preeclampsia and/or gestational diabetes (OR=1.94; 1.07 to 3.71; p=0.04). Interpretation: This study demonstrates a low ideal CVH prevalence in Chilean women. Education level was a significant factor associated with ideal CVH. But also, women-specific risk factors, such as a history of preeclampsia/gestational diabetes, and alcohol consumption, were important factors related to CVH. Funding: This study was supported by grants from Fundación SOCHICAR de la Sociedad Chilena de Cardiología y Cirugía Cardiovascular, the American Heart Association and an unrestricted grant by TEVA Pharmaceuticals.
Language	English
Publishing date	2021-09-11
Publishing country	England
Document type	Journal Article
ISSN	2667-193X
ISSN (online)	2667-193X
DOI	10.1016/j.lana.2021.100071
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Article: Mobile-phone text messaging to promote ideal cardiovascular health in women.

Acevedo, Monica / Varleta, Paola / Casas-Cordero, Carolina / Berríos, Amalia / Navarrete, Carlos / Valentino, Giovanna / Lopez, Rosario / Smith, Sidney C

Open heart

2022 Volume 10, Issue 1

Abstract: Objective: Ideal cardiovascular health (CVH) was developed to promote CVH as a key component of primordial prevention. Mobile short message service (SMS) is useful for improving health behaviours. We aim to test the effectiveness of SMS intervention in ... ...

Abstract	Objective: Ideal cardiovascular health (CVH) was developed to promote CVH as a key component of primordial prevention. Mobile short message service (SMS) is useful for improving health behaviours. We aim to test the effectiveness of SMS intervention in women to improve CVH. Methods: In a single-blinded, randomised, controlled study, 620 women, aged 35-70 years, without cardiovascular disease, were enrolled in SMS intervention versus no SMS. CVH metrics by self-report, and biochemical laboratory, anthropometric and blood pressure measurements were collected during home visits at baseline and 9 months. Women were categorised as having poor (0-2), intermediate (3-4) or ideal (5-7) CVH according to the number of ideal CVH metrics. Participants were randomised 1:1 to SMS intervention versus control. SMS was sent every 5-6 days for 9 months. The primary outcome was the difference in the proportion of women with ideal CVH between SMS and control groups at 9 months. Rates of intermediate CVH, poor CVH and each of the seven ideal CV health metrics at 9 months were key secondary endpoints. Results: At 9 months, there was no significant difference between groups for the primary outcome (16.3% at baseline and 13.3% at 9 months, and 10.1% and 11.1%, in SMS and control groups, respectively, adjusted RR 1.0; 95% CI 0.6 to 1.6). Similarly, there were no significant differences between groups for the key secondary endpoints. SMS had an acceptance rate of 94.9%. Conclusions: Behavioural SMS intervention did not improve rates of ideal CVH in women, despite being feasible and well received. Trial registration number: 6377.
MeSH term(s)	Humans ; Female ; Text Messaging ; Cell Phone ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/prevention & control ; Research Design
Language	English
Publishing date	2022-07-04
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2747269-3
ISSN	2053-3624
ISSN	2053-3624
DOI	10.1136/openhrt-2022-002214
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Article ; Online: Sustainable and circular agro-environmental practices: A review of the management of agricultural waste biomass in Spain and the Czech Republic.

Duque-Acevedo, Mónica / Ulloa-Murillo, Leidy Marcela / Belmonte-Ureña, Luis J / Camacho-Ferre, Francisco / Mercl, Filip / Tlustoš, Pavel

Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA

2022 Volume 41, Issue 5, Page(s) 955–969

Abstract: Sustainable and circular production models, such as the circular economy and circular bioeconomy, have become key mechanisms to leave behind the traditional linear model of food production. Under this approach and considering the waste biomass potential ... ...

Abstract	Sustainable and circular production models, such as the circular economy and circular bioeconomy, have become key mechanisms to leave behind the traditional linear model of food production. Under this approach and considering the waste biomass potential available in Spain and the Czech Republic, the main objective of this study is to analyse the most relevant aspects of the generation, use and regulation of agricultural waste biomass (AWB) in both countries. For this purpose, a scientometric analysis and systematic review of published research in the Scopus database were carried out. A complementary analysis of AWB management policies and regulations was also part of the methodology. The results show that Spain has published almost twice as much research as the Czech Republic. Furthermore, 91% of the retrieved research prioritizes the characterization and estimation of the potential of more than 15 AWB types. Among the main ones are olive residues, horticultural residues and wheat straw, which are used for producing organic amendments, bioenergy and biofuels. The results confirm that the reduction and valorization of AWB is an issue that has become more important in the last 13 years, mainly due to the policies and strategies for circular economy and circular bioeconomy. With this in mind, this study provides relevant information for governments on the aspects that need to be improved to advance in the valorization of AWB. This study also provides guidance to farmers on the reduction and/or recovery alternatives that they can implement to move towards sustainable and circular agriculture.
MeSH term(s)	Biomass ; Spain ; Czech Republic ; Waste Management ; Agriculture ; Biofuels
Chemical Substances	Biofuels
Language	English
Publishing date	2022-12-14
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1480483-9
ISSN	1096-3669 ; 1399-3070 ; 0734-242X
ISSN (online)	1096-3669 ; 1399-3070
ISSN	0734-242X
DOI	10.1177/0734242X221139122
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