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  1. Article: Traumatic lumbar hernia: A systematic review of the literature.

    Tsouknidas, Ioannis / Tasis, Nikolaos / Antonopoulou, Maria Ioanna / Acheimastos, Vasileios / Manatakis, Dimitrios K

    Chinese journal of traumatology = Zhonghua chuang shang za zhi

    2023  Volume 27, Issue 1, Page(s) 53–57

    Abstract: Purpose: Traumatic lumbar hernia (TLH) constitutes a protrusion of content through a defect in the posterior abdominal wall, as a result of injury. This rare entity has been described in limited number of cases.: Methods: A systematic review of the ... ...

    Abstract Purpose: Traumatic lumbar hernia (TLH) constitutes a protrusion of content through a defect in the posterior abdominal wall, as a result of injury. This rare entity has been described in limited number of cases.
    Methods: A systematic review of the literature was performed according to the meta-analysis of observational studies in epidemiology guidelines. The English literature from 1990 until 2021 was reviewed, using PubMed, EMBASE and Google Scholar bibliographic databases, to identify case reports and case series with patients that were diagnosed with TLH. For each eligible study, demographics, clinical presentation, hernia characteristics, preoperative imaging investigations, operation details, and postoperative data were extracted for assessment. Statistical analysis was performed on SPSS, version 20.0.
    Results: A total of 62 studies were included for review, with 164 patients with TLH. Mean age was (42.6 ± 14.3) years (47.6% males, 31.1% females, gender not specified in 35 cases). Mean diameter of hernia neck was (6.3 ± 3.1) cm, while the triangles of Petit and Grynfeltt were affected in 74.5% and 14.6%, respectively. Patients diagnosed in the emergency setting account for 54.2%, with CT scan establishing diagnosis in all but one case (97.7%). A delayed diagnosis was made in 45.8%, at a mean 1 year following trauma. Flank bulging (82.8%) and chronic back pain (34.3%) were the most frequent symptoms. In both delayed and acute group, open surgery (63.6% and 92.3%, respectively) was the preferred surgical approach. Postoperative complications were reported in 11.4% of acute and 15.0% of delayed patients. Hernia recurrence was 7%.
    Conclusions: TLH is uncommon with 164 cases described since 1990. CT scan is the gold standard in diagnosis. Open surgery is generally the preferred approach, particularly in the emergency setting. Acute TLH can be treated either by primary suture repair or mesh, depending on the local conditions, whereas delayed cases usually require a mesh.
    MeSH term(s) Male ; Female ; Humans ; Adult ; Middle Aged ; Herniorrhaphy/methods ; Surgical Mesh ; Hernia, Abdominal/epidemiology ; Hernia, Abdominal/etiology ; Hernia, Abdominal/surgery ; Tomography, X-Ray Computed ; Laparoscopy
    Language English
    Publishing date 2023-06-02
    Publishing country China
    Document type Systematic Review ; Meta-Analysis ; Journal Article ; Review
    ZDB-ID 2276839-7
    ISSN 1008-1275
    ISSN 1008-1275
    DOI 10.1016/j.cjtee.2023.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Primary adrenal Ewing sarcoma: A systematic review of the literature.

    Manatakis, Dimitrios K / Tsouknidas, Ioannis / Mylonakis, Emmanouil / Tasis, Nikolaos / Antonopoulou, Maria Ioanna / Acheimastos, Vasileios / Mastoropoulou, Aikaterini / Korkolis, Dimitrios P

    World journal of clinical cases

    2023  Volume 11, Issue 28, Page(s) 6782–6791

    Abstract: Background: Ewing sarcoma (ES) is a malignant neoplasm of neuroectodermal origin and is commonly observed in children and young adults. The musculoskeletal system is the main body system impacted and ES is rarely seen in the visceral organs particularly ...

    Abstract Background: Ewing sarcoma (ES) is a malignant neoplasm of neuroectodermal origin and is commonly observed in children and young adults. The musculoskeletal system is the main body system impacted and ES is rarely seen in the visceral organs particularly the adrenal gland.
    Aim: To present a comprehensive review of primary adrenal ES, with emphasis on diagnosis, therapy and oncological outcomes.
    Methods: A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020. PubMed/ MEDLINE, EMBASE and Google Scholar bibliographic databases were searched to identify articles from 1989 to 2022 and included patients with ES/primitive neuroectodermal tumor (PNET) of the adrenal gland. PubMed, Google Scholar and EMBASE medical databases were searched, combining the terms "adrenal", "ES" and "PNET". Demographic, clinical, pathological and oncological data of patients were analyzed by SPSS version 29.0.
    Results: A total of 52 studies were included for review (47 case reports and 5 case series) with 66 patients reported to have primary adrenal ES. Mean age at diagnosis was 26.4 ± 15.4 years (37.9% males, 57.6% females, sex not reported in 3 cases). The most frequent complaint was abdominal/flank pain or discomfort (46.4%) followed by a palpable mass (25.0%), and the average duration of symptoms was 2.6 ± 3.1 mo. The imaging modality of choice was computed tomography scan (81.5%), followed by magnetic resonance imaging (20.4%). Preoperative staging revealed that 17 tumors (27.9%) were metastatic and 14 patients had inferior vena cava or renal vein neoplastic thrombus at initial diagnosis. Open adrenalectomy was performed in the majority of cases (80.0%), of which 27.9% required more extensive resection. Minimally invasive surgery was attempted in 8.2% of tumors. Complete surgical resection was achieved in 89.4% of the patients. Adjuvant therapy was administered to 32 patients, in the form of chemotherapy (62.5%), radiotherapy (3.1%) or combination (34.4%). Median overall survival was 15 mo and 24-mo overall survival was 40.5%. Median disease-free survival was 10 mo and 24-mo disease-free survival was 33.3%.
    Conclusion: The significant progress in molecular biology and genetics of ES does not reflect on patient outcomes. ES remains an aggressive tumor with a poor prognosis and high mortality.
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v11.i28.6782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Gastrointestinal Seed Bezoars: A Systematic Review of Case Reports and Case Series.

    Manatakis, Dimitrios K / Acheimastos, Vasileios / Antonopoulou, Maria Ioanna / Balalis, Dimitrios / Korkolis, Dimitris P

    Cureus

    2019  Volume 11, Issue 5, Page(s) e4686

    Abstract: Seed bezoars are a distinct subcategory of phytobezoars, caused by indigestible vegetable or fruit seeds. The aim of our study was to present a comprehensive review on seed bezoars, focusing on epidemiology, symptomatology, diagnosis and treatment ... ...

    Abstract Seed bezoars are a distinct subcategory of phytobezoars, caused by indigestible vegetable or fruit seeds. The aim of our study was to present a comprehensive review on seed bezoars, focusing on epidemiology, symptomatology, diagnosis and treatment options. A systematic review of the English literature (1980-2018) was conducted, using PubMed, Embase and Google Scholar databases. Fifty-two studies fulfilled the inclusion criteria, with a total of 153 patients, the majority of whom (72%) came from countries around the Eastern Mediterranean and the Middle East. Patients complained primarily about constipation (63%), abdominal/rectal pain (19%) or intestinal obstruction (17%). Most seed bezoars were found in the rectum (78%) and the terminal ileum (16%). Risk factors were recognised in 12% of cases. Manual disimpaction under general anaesthesia was the procedure of choice in 69%, while surgery was required in 22% of cases. Seed bezoars appear to represent a different pathophysiological process compared to fibre bezoars. Seeds usually pass through the pylorus and ileocaecal valve, due to their small size, and accumulate gradually in the colon. Seed bezoars are usually found in the rectum of patients without predisposing factors, causing constipation and pain. History and digital rectal examination are the mainstay of diagnosis, with manual extraction under general anaesthesia being the procedure of choice.
    Language English
    Publishing date 2019-05-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.4686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Revisiting Amyand's Hernia: A 20-Year Systematic Review.

    Manatakis, Dimitrios K / Tasis, Nikolaos / Antonopoulou, Maria Ioanna / Anagnostopoulos, Petros / Acheimastos, Vasileios / Papageorgiou, Dimitrios / Fradelos, Evangelos / Zoulamoglou, Menelaos / Agalianos, Christos / Tsiaoussis, John / Xynos, Evaghelos

    World journal of surgery

    2021  Volume 45, Issue 6, Page(s) 1763–1770

    Abstract: Purpose: Protrusion of the appendix within an inguinal hernia is termed an Amyand's hernia. A systematic review of case reports and case series of Amyand's hernia was performed, with emphasis on surgical decision-making.: Methods: The English ... ...

    Abstract Purpose: Protrusion of the appendix within an inguinal hernia is termed an Amyand's hernia. A systematic review of case reports and case series of Amyand's hernia was performed, with emphasis on surgical decision-making.
    Methods: The English literature (2000-2019) was reviewed, using PubMed and Embase, combining the terms "hernia", "inguinal", "appendix", "appendicitis" and "Amyand". Overall, 231 studies were included, describing 442 patients.
    Results: Mean age of patients was 34 ± 32 years (adults 57.5%, children 42.5%). 91% were males, while a left-sided Amyand's hernia was observed in 9.5%. Of 156 elective hernia repairs, 38.5% underwent appendectomy and 61.5% simple reduction of the appendix. 88% of the adult patients had a mesh repair, without complications. Of 281 acute cases, hernial complications (76%) and acute appendicitis (12%) were the most common preoperative surgical indications. Appendectomy was performed in 79%, more extensive operations in 8% and simple reduction in 13% of cases. A mesh was used in 19% of adult patients following any type of resection and in 81% following reduction of the appendix. Among acute cases, mortality was 1.8% and morbidity 9.2%. Surgical site infections were observed in 3.6%, all of which in patients without mesh implantation.
    Conclusion: In elective Amyand's hernia cases, appendectomy may be considered in certain patients, provided faecal spillage is avoided, to prevent mesh infection. In cases of appendicitis, prosthetic mesh may be used, if the surgical field is relatively clean, whereas endogenous tissue repairs are preferred in cases of heavy contamination.
    MeSH term(s) Adolescent ; Adult ; Aged ; Appendectomy ; Appendicitis/complications ; Appendicitis/surgery ; Appendix/surgery ; Child ; Child, Preschool ; Hernia, Inguinal/surgery ; Herniorrhaphy ; Humans ; Male ; Middle Aged ; Young Adult
    Language English
    Publishing date 2021-02-17
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-021-05983-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago.

    Perrone, Gennaro / Giuffrida, Mario / Abu-Zidan, Fikri / Kruger, Vitor F / Livrini, Marco / Petracca, Gabriele Luciano / Rossi, Giorgio / Tarasconi, Antonio / Tian, Brian W C A / Bonati, Elena / Mentz, Ricardo / Mazzini, Federico N / Campana, Juan P / Gasser, Elisabeth / Kafka-Ritsch, Reinhold / Felsenreich, Daniel M / Dawoud, Christopher / Riss, Stefan / Gomes, Carlos Augusto /
    Gomes, Felipe Couto / Gonzaga, Ricardo Alessandro Teixeira / Canton, Cassio Alfred Brattig / Pereira, Bruno Monteiro / Fraga, Gustavo P / Zem, Leticia Gonçalves / Cordeiro-Fonseca, Vinicius / de Mesquita Tauil, Renato / Atanasov, Boyko / Belev, Nikolay / Kovachev, Nikola / Meléndez, L Juan José / Dimova, Ana / Dimov, Stefan / Zelić, Zdravko / Augustin, Goran / Bogdanić, Branko / Morić, Trpimir / Chouillard, Elie / Bajul, Melinda / De Simone, Belinda / Panis, Yves / Esposito, Francesco / Notarnicola, Margherita / Lauka, Lelde / Fabbri, Anna / Hentati, Hassen / Fnaiech, Iskander / Aurélien, Venara / Bougard, Marie / Roulet, Maxime / Demetrashvili, Zaza / Pipia, Irakli / Merabishvili, Giorgi / Bouliaris, Konstantinos / Koukoulis, Georgios / Doudakmanis, Christos / Xenaki, Sofia / Chrysos, Emmanuel / Kokkinakis, Stamatios / Vassiliu, Panteleimon / Michalopoulos, Nikolaos / Margaris, Ioannis / Kechagias, Aristotelis / Avgerinos, Konstantinos / Katunin, Jevgeni / Lostoridis, Eftychios / Nagorni, Eleni-Aikaterini / Pujante, Antonio / Mulita, Francesk / Maroulis, Ioannis / Vailas, Michail / Marinis, Athanasios / Siannis, Ioannis / Bourbouteli, Eirini / Manatakis, Dimitrios K / Tasis, Nikolaos / Acheimastos, Vasileios / Maria, Sotiropoulou / Stylianos, Kapiris / Kuzeridis, Harilaos / Korkolis, Dimitrios / Fradelos, Evangelos / Kavalieratos, George / Petropoulou, Thalia / Polydorou, Andreas / Papacostantinou, Ioannis / Triantafyllou, Tania / Kimpizi, Despina / Theodorou, Dimitrios / Toutouzas, Konstantinos / Chamzin, Alexandros / Frountzas, Maximos / Schizas, Dimitrios / Karavokyros, Ioannis / Syllaios, Athanasios / Charalabopoulos, Alexandros / Boura, Maria / Baili, Efstratia / Ioannidis, Orestis / Loutzidou, Lydia / Anestiadou, Elissavet / Tsouknidas, Ioannis / Petrakis, Georgios / Polenta, Eleni / Bains, Lovenish / Gupta, Rahul / Singh, Sudhir K / Khanduri, Archana / Bala, Miklosh / Kedar, Asaf / Pisano, Marcello / Podda, Mauro / Pisanu, Adolfo / Martines, Gennaro / Trigiante, Giuseppe / Lantone, Giuliano / Agrusa, Antonino / Di Buono, Giuseppe / Buscemi, Salvatore / Veroux, Massimiliano / Gioco, Rossella / Veroux, Gastone / Oragano, Luigi / Zonta, Sandro / Lovisetto, Federico / Feo, Carlo V / Pesce, Antonio / Fabbri, Nicolò / Lantone, Giulio / Marino, Fabio / Perrone, Fabrizio / Vincenti, Leonardo / Papagni, Vincenzo / Picciariello, Arcangelo / Rossi, Stefano / Picardi, Biagio / Del Monte, Simone Rossi / Visconti, Diego / Osella, Giulia / Petruzzelli, Luca / Pignata, Giusto / Andreuccetti, Jacopo / D'Alessio, Rossella / Buonfantino, Massimo / Guaitoli, Eleonora / Spinelli, Stefano / Sampietro, Gianluca Matteo / Corbellini, Carlo / Lorusso, Leonardo / Frontali, Alice / Pezzoli, Isabella / Bonomi, Alessandro / Chierici, Andrea / Cotsoglou, Christian / Manca, Giuseppe / Delvecchio, Antonella / Musa, Nicola / Casati, Massimiliano / Letizia, Laface / Abate, Emmanuele / Ercolani, Giorgio / D'Acapito, Fabrizio / Solaini, Leonardo / Guercioni, Gianluca / Cicconi, Simone / Sasia, Diego / Borghi, Felice / Giraudo, Giorgio / Sena, Giuseppe / Castaldo, Pasquale / Cardamone, Eugenia / Portale, Giuseppe / Zuin, Matteo / Spolverato, Ylenia / Esposito, Marialusia / Isernia, Roberta Maria / Di Salvo, Maria / Manunza, Romina / Esposito, Giuseppe / Agus, Marcello / Asti, Emanuele Luigi Giuseppe / Bernardi, Daniele Tiziano / Tonucci, Tommaso Panici / Luppi, Davide / Casadei, Massimiliano / Bonilauri, Stefano / Pezzolla, Angela / Panebianco, Annunziata / Laforgia, Rita / De Luca, Maurizio / Zese, Monica / Parini, Dario / Jovine, Elio / De Sario, Giuseppina / Lombardi, Raffaele / Aprea, Giovanni / Palomba, Giuseppe / Capuano, Marianna / Argenio, Giulio / Orio, Gianluca / Armellino, Mariano Fortunato / Troian, Marina / Guerra, Martina / Nagliati, Carlo / Biloslavo, Alan / Germani, Paola / Aizza, Giada / Monsellato, Igor / Chahrour, Ali Chaouki / Anania, Gabriele / Bombardini, Cristina / Bagolini, Francesco / Sganga, Gabriele / Fransvea, Pietro / Bianchi, Valentina / Boati, Paolo / Ferrara, Francesco / Palmieri, Francesco / Cianci, Pasquale / Gattulli, Domenico / Restini, Enrico / Cillara, Nicola / Cannavera, Alessandro / Nita, Gabriela Elisa / Sarnari, Jlenia / Roscio, Francesco / Clerici, Federico / Scandroglio, Ildo / Berti, Stefano / Cadeo, Alessandro / Filippelli, Alice / Conti, Luigi / Grassi, Carmine / Cattaneo, Gaetano Maria / Pighin, Marina / Papis, Davide / Gambino, Giovanni / Bertino, Vanessa / Schifano, Domenico / Prando, Daniela / Fogato, Luisella / Cavallo, Fabio / Ansaloni, Luca / Picheo, Roberto / Pontarolo, Nicholas / Depalma, Norma / Spampinato, Marcello / D'Ugo, Stefano / Lepre, Luca / Capponi, Michela Giulii / Campa, Rossella Domenica / Sarro, Giuliano / Dinuzzi, Vincenza Paola / Olmi, Stefano / Uccelli, Matteo / Ferrari, Davide / Inama, Marco / Moretto, Gianluigi / Fontana, Michele / Favi, Francesco / Picariello, Erika / Rampini, Alessia / Barberis, Andrea / Azzinnaro, Antonio / Oliva, Alba / Totaro, Luigi / Benzoni, Ilaria / Ranieri, Valerio / Capolupo, Gabriella Teresa / Carannante, Filippo / Caricato, Marco / Ronconi, Maurizio / Casiraghi, Silvia / Casole, Giovanni / Pantalone, Desire / Alemanno, Giovanni / Scheiterle, Maximilian / Ceresoli, Marco / Cereda, Marco / Fumagalli, Chiara / Zanzi, Federico / Bolzon, Stefano / Guerra, Enrico / Lecchi, Francesca / Cellerino, Paola / Ardito, Antonella / Scaramuzzo, Rosa / Balla, Andrea / Lepiane, Pasquale / Tartaglia, Nicola / Ambrosi, Antonio / Pavone, Giovanna / Palini, Gian Marco / Veneroni, Simone / Garulli, Gianluca / Ricci, Claudio / Torre, Beatrice / Russo, Iris Shari / Rottoli, Matteo / Tanzanu, Marta / Belvedere, Angela / Milone, Marco / Manigrasso, Michele / De Palma, Giovanni Domenico / Piccoli, Micaela / Pattacini, Gianmaria Casoni / Magnone, Stefano / Bertoli, Paolo / Pisano, Michele / Massucco, Paolo / Palisi, Marco / Luzzi, Andrea-Pierre / Fleres, Francesco / Clarizia, Guglielmo / Spolini, Alessandro / Kobe, Yoshiro / Toma, Takayuki / Shimamura, Fumihiko / Parker, Robert / Ranketi, Sinkeet / Mitei, Mercy / Svagzdys, Saulius / Pauzas, Henrikas / Zilinskas, Justas / Poskus, Tomas / Kryzauskas, Marius / Jakubauskas, Matas / Zakaria, Andee Dzulkarnaen / Zakaria, Zaidi / Wong, Michael Pak-Kai / Jusoh, Asri Che / Zakaria, Muhammad Nazreen / Cruz, Daniel Rios / Elizalde, Aurea Barbara Rodriguez / Reynaud, Alejandro Bañon / Hernandez, Edgard Efren Lozada / Monroy, Jose Maria Victor Palomo / Hinojosa-Ugarte, Diego / Quiodettis, Martha / Du Bois, María Esther / Latorraca, José / Major, Piotr / Pędziwiatr, Michał / Pisarska-Adamczyk, Magdalena / Walędziak, Maciej / Kwiatkowski, Andrzej / Czyżykowski, Łukasz / da Costa, Silvia Dantas / Pereira, Bela / Ferreira, Ana Rita Oliveira / Almeida, Filipe / Rocha, Ricardo / Carneiro, Carla / Perez, Diego Pita / Carvas, João / Rocha, Catarina / Ferreira, Cátia / Marques, Rita / Fernandes, Urânia / Leao, Pedro / Goulart, André / Pereira, Rita Gonçalves / Patrocínio, Sara Daniela Direito / de Mendonça, Nuno Gonçalo Gonçalves / Manso, Maria Isabel Cerqueira / Morais, Henrique Manuel Cardoso / Cardoso, Paulo Sebastião / Calu, Valentin / Miron, Adrian / Toma, Elena Adelina / Gachabayov, Mahir / Abdullaev, Abakar / Litvin, Andrey / Nechay, Taras / Tyagunov, Alexander / Yuldashev, Anvar / Bradley, Alison / Wilson, Michael / Panyko, Arpád / Látečková, Zuzana / Lacko, Vladimír / Lesko, Dusan / Soltes, Marek / Radonak, Jozef / Turrado-Rodriguez, Victor / Termes-Serra, Roser / Morales-Sevillano, Xavier / Lapolla, Pierfrancesco / Mingoli, Andrea / Brachini, Gioia / Degiuli, Maurizio / Sofia, Silvia / Reddavid, Rossella / de Manzoni Garberini, Andrea / Buffone, Angelica / Del Pozo, Eduardo Perea / Aparicio-Sánchez, Daniel / Dos Barbeito, Sandra / Estaire-Gómez, Mercedes / Vitón-Herrero, Rebeca / de Los Ángeles Gil Olarte-Marquez, Mª / Gil-Martínez, José / Alconchel, Felipe / Nicolás-López, Tatiana / Rahy-Martin, Aida Cristina / Pelloni, María / Bañolas-Suarez, Raquel / Mendoza-Moreno, Fernando / Nisa, Francisca García-Moreno / Díez-Alonso, Manuel / Rodas, María Elisa Valle / Agundez, María Carmona / Andrés, María Inmaculada Pérez / Moreira, Claudia Cristina Lopes / Perez, Aintzane Lizarazu / Ponce, Iñigo Augusto / González-Castillo, Ana María / Membrilla-Fernández, Estela / Salvans, Silvia / Serradilla-Martín, Mario / Pardo, Pablo Sancho / Rivera-Alonso, Daniel / Dziakova, Jana / Huguet, Jose Mugüerza / Valle, Naila Pagès / Ruiz, Enrique Colás / Valcárcel, Cristina Rey / Moreno, Cristina Ruiz / Salazar, Yeniffer Tatiana Moreno / García, Juan Jesús Rubio / Micó, Silvia Sevila / López, Joaquín Ruiz / Farré, Silvia Pérez / Gomez, Maite Santamaria / Petit, Nuria Mestres / Titos-García, Alberto / Aranda-Narváez, Jose Manuel / Romacho-López, Laura / Sánchez-Guillén, Luis / Aranaz-Ostariz, Veronica / Bosch-Ramírez, Marina / Martínez-Pérez, Aleix / Martínez-López, Elías / Sebastián-Tomás, Juan Carlos / Jimenez-Riera, Granada / Jimenez-Vega, Javier / Cuellar, Jose Aurelio Navas / Campos-Serra, Andrea / Muñoz-Campaña, Anna / Gràcia-Roman, Raquel / Alegre, Javier Martínez / Pinto, Francisca Lima / O'Sullivan, Sara Nuñez / Antona, Francisco Blanco / Jiménez, Beatriz Muñoz / López-Sánchez, Jaime / Carmona, Zahira Gómez / Fernández, Rocio Torres / Sierra, Isabel Blesa / de León, Laura Román García / Moreno, Verónica Polaino / Iglesias, Eva / Cumplido, Paola Lora / Bravo, Altea Arango / Simó, Ignacio Rey / Domínguez, Carlota López / Caamaño, Aloia Guerreiro / Lozano, Rafael Calleja / Martínez, Manuel Durán / Torres, Álvaro Naranjo / de Quiros, Javier Tomas Morales Bernaldo / Pellino, Gianluca / Cloquell, Miriam Moratal / Moller, Elsa García / Jalal-Eldin, Sami / Abdoun, Ahmed K / Hamid, Hytham K S / Lohsiriwat, Varut / Mongkhonsupphawan, Aitsariya / Baraket, Oussama / Ayed, Karim / Abbassi, Imed / Ali, Ali Ben / Ammar, Houssem / Kchaou, Ali / Tlili, Ahmed / Zribi, Imen / Colak, Elif / Polat, Suleyman / Koylu, Zehra Alan / Guner, Ali / Usta, Mehmet Arif / Reis, Murat Emre / Mantoglu, Baris / Gonullu, Emre / Akin, Emrah / Altintoprak, Fatih / Bayhan, Zulfu / Firat, Necattin / Isik, Arda / Memis, Ufuk / Bayrak, Mehmet / Altıntaş, Yasemin / Kara, Yasin / Bozkurt, Mehmet Abdussamet / Kocataş, Ali / Das, Koray / Seker, Ahmet / Ozer, Nazmi / Atici, Semra Demirli / Tuncer, Korhan / Kaya, Tayfun / Ozkan, Zeynep / Ilhan, Onur / Agackiran, Ibrahim / Uzunoglu, Mustafa Yener / Demirbas, Eren / Altinel, Yuksel / Meric, Serhat / Hacım, Nadir Adnan / Uymaz, Derya Salim / Omarov, Nail / Balık, Emre / Tebala, Giovanni D / Khalil, Hany / Rana, Mridul / Khan, Mansoor / Florence, Charlotte / Swaminathan, Christie / Leo, Cosimo Alex / Liasis, Lampros / Watfah, Josef / Trostchansky, Ivan / Delgado, Edward / Pontillo, Marcelo / Latifi, Rifat / Coimbra, Raul / Edwards, Sara / Lopez, Ana / Velmahos, George / Dorken, Ander / Gebran, Anthony / Palmer, Amanda / Oury, Jeffrey / Bardes, James M / Seng, Sirivan Suon / Coffua, Lauren S / Ratnasekera, Asanthi / Egodage, Tanya / Echeverria-Rosario, Karla / Armento, Isabella / Napolitano, Lena M / Sangji, Naveen F / Hemmila, Mark / Quick, Jacob A / Austin, Tyler R / Hyman, Theodore S / Curtiss, William / McClure, Amanda / Cairl, Nicholas / Biffl, Walter L / Truong, Hung P / Schaffer, Kathryn / Reames, Summer / Banchini, Filippo / Capelli, Patrizio / Coccolini, Federico / Sartelli, Massimo / Bravi, Francesca / Vallicelli, Carlo / Agnoletti, Vanni / Baiocchi, Gian Luca / Catena, Fausto

    World journal of emergency surgery : WJES

    2024  Volume 19, Issue 1, Page(s) 14

    Abstract: Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute ... ...

    Abstract Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA.
    Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up.
    Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections.
    Conclusions: After 100 years since the first Hartmann's procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment's choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception.
    MeSH term(s) Female ; Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Emergencies ; Prospective Studies ; Postoperative Complications/etiology ; Anastomosis, Surgical/methods ; Colorectal Neoplasms/surgery
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2233734-9
    ISSN 1749-7922 ; 1749-7922
    ISSN (online) 1749-7922
    ISSN 1749-7922
    DOI 10.1186/s13017-024-00543-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?

    De Simone, Belinda / Abu-Zidan, Fikri M / Chouillard, Elie / Di Saverio, Salomone / Sartelli, Massimo / Podda, Mauro / Gomes, Carlos Augusto / Moore, Ernest E / Moug, Susan J / Ansaloni, Luca / Kluger, Yoram / Coccolini, Federico / Landaluce-Olavarria, Aitor / Estraviz-Mateos, Begoña / Uriguen-Etxeberria, Ana / Giordano, Alessio / Luna, Alfonso Palmieri / Amín, Luz Adriana Hernández / Hernández, Adriana María Palmieri /
    Shabana, Amanda / Dzulkarnaen, Zakaria Andee / Othman, Muhammad Asyraf / Sani, Mohamad Ikhwan / Balla, Andrea / Scaramuzzo, Rosa / Lepiane, Pasquale / Bottari, Andrea / Staderini, Fabio / Cianchi, Fabio / Cavallaro, Andrea / Zanghì, Antonio / Cappellani, Alessandro / Campagnacci, Roberto / Maurizi, Angela / Martinotti, Mario / Ruggieri, Annamaria / Jusoh, Asri Che / Rahman, Karim Abdul / Zulkifli, Anis Suraya M / Petronio, Barbara / Matías-García, Belén / Quiroga-Valcárcel, Ana / Mendoza-Moreno, Fernando / Atanasov, Boyko / Campanile, Fabio Cesare / Vecchioni, Ilaria / Cardinali, Luca / Travaglini, Grazia / Sebastiani, Elisa / Chooklin, Serge / Chuklin, Serhii / Cianci, Pasquale / Restini, Enrico / Capuzzolo, Sabino / Currò, Giuseppe / Filippo, Rosalinda / Rispoli, Michele / Aparicio-Sánchez, Daniel / Muñóz-Cruzado, Virginia Durán / Barbeito, Sandra Dios / Delibegovic, Samir / Kesetovic, Amar / Sasia, Diego / Borghi, Felice / Giraudo, Giorgio / Visconti, Diego / Doria, Emanuele / Santarelli, Mauro / Luppi, Davide / Bonilauri, Stefano / Grossi, Ugo / Zanus, Giacomo / Sartori, Alberto / Piatto, Giacomo / De Luca, Maurizio / Vita, Domenico / Conti, Luigi / Capelli, Patrizio / Cattaneo, Gaetano Maria / Marinis, Athanasios / Vederaki, Styliani-Aikaterini / Bayrak, Mehmet / Altıntas, Yasemin / Uzunoglu, Mustafa Yener / Demirbas, Iskender Eren / Altinel, Yuksel / Meric, Serhat / Aktimur, Yunus Emre / Uymaz, Derya Salim / Omarov, Nail / Azamat, Ibrahim / Lostoridis, Eftychios / Nagorni, Eleni-Aikaterini / Pujante, Antonio / Anania, Gabriele / Bombardini, Cristina / Bagolini, Francesco / Gonullu, Emre / Mantoglu, Baris / Capoglu, Recayi / Cappato, Stefano / Muzio, Elena / Colak, Elif / Polat, Suleyman / Koylu, Zehra Alan / Altintoprak, Fatih / Bayhan, Zülfü / Akin, Emrah / Andolfi, Enrico / Rezart, Sulce / Kim, Jae Il / Jung, Sung Won / Shin, Yong Chan / Enciu, Octavian / Toma, Elena Adelina / Medas, Fabio / Canu, Gian Luigi / Cappellacci, Federico / D'Acapito, Fabrizio / Ercolani, Giorgio / Solaini, Leonardo / Roscio, Francesco / Clerici, Federico / Gelmini, Roberta / Serra, Francesco / Rossi, Elena Giulia / Fleres, Francesco / Clarizia, Guglielmo / Spolini, Alessandro / Ferrara, Francesco / Nita, Gabriela / Sarnari, Jlenia / Gachabayov, Mahir / Abdullaev, Abakar / Poillucci, Gaetano / Palini, Gian Marco / Veneroni, Simone / Garulli, Gianluca / Piccoli, Micaela / Pattacini, Gianmaria Casoni / Pecchini, Francesca / Argenio, Giulio / Armellino, Mariano Fortunato / Brisinda, Giuseppe / Tedesco, Silvia / Fransvea, Pietro / Ietto, Giuseppe / Franchi, Caterina / Carcano, Giulio / Martines, Gennaro / Trigiante, Giuseppe / Negro, Giulia / Vega, Gustavo Machain / González, Agustín Rodríguez / Ojeda, Leonardo / Piccolo, Gaetano / Bondurri, Andrea / Maffioli, Anna / Guerci, Claudio / Sin, Boo Han / Zuhdi, Zamri / Azman, Azlanudin / Mousa, Hussam / Al Bahri, Shadi / Augustin, Goran / Romic, Ivan / Moric, Trpimir / Nikolopoulos, Ioannis / Andreuccetti, Jacopo / Pignata, Giusto / D'Alessio, Rossella / Kenig, Jakub / Skorus, Urszula / Fraga, Gustavo Pereira / Hirano, Elcio Shiyoiti / de Lima Bertuol, Jackson Vinícius / Isik, Arda / Kurnaz, Eray / Asghar, Mohammad Sohail / Afzal, Ameer / Akbar, Ali / Nikolouzakis, Taxiarchis Konstantinos / Lasithiotakis, Konstantinos / Chrysos, Emmanuel / Das, Koray / Özer, Nazmi / Seker, Ahmet / Ibrahim, Mohamed / Hamid, Hytham K S / Babiker, Ahmed / Bouliaris, Konstantinos / Koukoulis, George / Kolla, Chrysoula-Christina / Lucchi, Andrea / Agostinelli, Laura / Taddei, Antonio / Fortuna, Laura / Agostini, Carlotta / Licari, Leo / Viola, Simona / Callari, Cosimo / Laface, Letizia / Abate, Emmanuele / Casati, Massimiliano / Anastasi, Alessandro / Canonico, Giuseppe / Gabellini, Linda / Tosi, Lorenzo / Guariniello, Anna / Zanzi, Federico / Bains, Lovenish / Sydorchuk, Larysa / Iftoda, Oksana / Sydorchuk, Andrii / Malerba, Michele / Costanzo, Federico / Galleano, Raffaele / Monteleone, Michela / Costanzi, Andrea / Riva, Carlo / Walędziak, Maciej / Kwiatkowski, Andrzej / Czyżykowski, Łukasz / Major, Piotr / Strzałka, Marcin / Matyja, Maciej / Natkaniec, Michal / Valenti, Maria Rosaria / Di Vita, Maria Domenica Pia / Sotiropoulou, Maria / Kapiris, Stylianos / Massalou, Damien / Veroux, Massimiliano / Volpicelli, Alessio / Gioco, Rossella / Uccelli, Matteo / Bonaldi, Marta / Olmi, Stefano / Nardi, Matteo / Livadoti, Giada / Mesina, Cristian / Dumitrescu, Theodor Viorel / Ciorbagiu, Mihai Calin / Ammendola, Michele / Ammerata, Giorgio / Romano, Roberto / Slavchev, Mihail / Misiakos, Evangelos P / Pikoulis, Emmanouil / Papaconstantinou, Dimitrios / Elbahnasawy, Mohamed / Abdel-Elsalam, Sherief / Felsenreich, Daniel M / Jedamzik, Julia / Michalopoulos, Nikolaos V / Sidiropoulos, Theodoros A / Papadoliopoulou, Maria / Cillara, Nicola / Deserra, Antonello / Cannavera, Alessandro / Negoi, Ionuţ / Schizas, Dimitrios / Syllaios, Athanasios / Vagios, Ilias / Gourgiotis, Stavros / Dai, Nick / Gurung, Rekha / Norrey, Marcus / Pesce, Antonio / Feo, Carlo Vittorio / Fabbri, Nicolo' / Machairas, Nikolaos / Dorovinis, Panagiotis / Keramida, Myrto D / Mulita, Francesk / Verras, Georgios Ioannis / Vailas, Michail / Yalkin, Omer / Iflazoglu, Nidal / Yigit, Direnc / Baraket, Oussama / Ayed, Karim / Ghalloussi, Mohamed Hedi / Patias, Parmenion / Ntokos, Georgios / Rahim, Razrim / Bala, Miklosh / Kedar, Asaf / Sawyer, Robert G / Trinh, Anna / Miller, Kelsey / Sydorchuk, Ruslan / Knut, Ruslan / Plehutsa, Oleksandr / Liman, Rumeysa Kevser / Ozkan, Zeynep / Kader, Saleh Abdel / Gupta, Sanjay / Gureh, Monika / Saeidi, Sara / Aliakbarian, Mohsen / Dalili, Amin / Shoko, Tomohisa / Kojima, Mitsuaki / Nakamoto, Raira / Atici, Semra Demirli / Tuncer, Gizem Kilinc / Kaya, Tayfun / Delis, Spiros G / Rossi, Stefano / Picardi, Biagio / Del Monte, Simone Rossi / Triantafyllou, Tania / Theodorou, Dimitrios / Pintar, Tadeja / Salobir, Jure / Manatakis, Dimitrios K / Tasis, Nikolaos / Acheimastos, Vasileios / Ioannidis, Orestis / Loutzidou, Lydia / Symeonidis, Savvas / de Sá, Tiago Correia / Rocha, Mónica / Guagni, Tommaso / Pantalone, Desiré / Maltinti, Gherardo / Khokha, Vladimir / Abdel-Elsalam, Wafaa / Ghoneim, Basma / López-Ruiz, José Antonio / Kara, Yasin / Zainudin, Syaza / Hayati, Firdaus / Azizan, Nornazirah / Khei, Victoria Tan Phooi / Yi, Rebecca Choy Xin / Sellappan, Harivinthan / Demetrashvili, Zaza / Lekiashvili, Nika / Tvaladze, Ana / Froiio, Caterina / Bernardi, Daniele / Bonavina, Luigi / Gil-Olarte, Angeles / Grassia, Sebastiano / Romero-Vargas, Estela / Bianco, Francesco / Gumbs, Andrew A / Dogjani, Agron / Agresta, Ferdinando / Litvin, Andrey / Balogh, Zsolt J / Gendrikson, George / Martino, Costanza / Damaskos, Dimitrios / Pararas, Nikolaos / Kirkpatrick, Andrew / Kurtenkov, Mikhail / Gomes, Felipe Couto / Pisanu, Adolfo / Nardello, Oreste / Gambarini, Fabrizio / Aref, Hager / Angelis, Nicola De' / Agnoletti, Vanni / Biondi, Antonio / Vacante, Marco / Griggio, Giulia / Tutino, Roberta / Massani, Marco / Bisetto, Giovanni / Occhionorelli, Savino / Andreotti, Dario / Lacavalla, Domenico / Biffl, Walter L / Catena, Fausto

    World journal of emergency surgery : WJES

    2022  Volume 17, Issue 1, Page(s) 61

    Abstract: Background: The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during the COVID-19 pandemic. The aim of the ChoCO-W study was to compare the clinical findings and outcomes of acute cholecystitis ... ...

    Abstract Background: The incidence of the highly morbid and potentially lethal gangrenous cholecystitis was reportedly increased during the COVID-19 pandemic. The aim of the ChoCO-W study was to compare the clinical findings and outcomes of acute cholecystitis in patients who had COVID-19 disease with those who did not.
    Methods: Data were prospectively collected over 6 months (October 1, 2020, to April 30, 2021) with 1-month follow-up. In October 2020, Delta variant of SARS CoV-2 was isolated for the first time. Demographic and clinical data were analyzed and reported according to the STROBE guidelines. Baseline characteristics and clinical outcomes of patients who had COVID-19 were compared with those who did not.
    Results: A total of 2893 patients, from 42 countries, 218 centers, involved, with a median age of 61.3 (SD: 17.39) years were prospectively enrolled in this study; 1481 (51%) patients were males. One hundred and eighty (6.9%) patients were COVID-19 positive, while 2412 (93.1%) were negative. Concomitant preexisting diseases including cardiovascular diseases (p < 0.0001), diabetes (p < 0.0001), and severe chronic obstructive airway disease (p = 0.005) were significantly more frequent in the COVID-19 group. Markers of sepsis severity including ARDS (p < 0.0001), PIPAS score (p < 0.0001), WSES sepsis score (p < 0.0001), qSOFA (p < 0.0001), and Tokyo classification of severity of acute cholecystitis (p < 0.0001) were significantly higher in the COVID-19 group. The COVID-19 group had significantly higher postoperative complications (32.2% compared with 11.7%, p < 0.0001), longer mean hospital stay (13.21 compared with 6.51 days, p < 0.0001), and mortality rate (13.4% compared with 1.7%, p < 0.0001). The incidence of gangrenous cholecystitis was doubled in the COVID-19 group (40.7% compared with 22.3%). The mean wall thickness of the gallbladder was significantly higher in the COVID-19 group [6.32 (SD: 2.44) mm compared with 5.4 (SD: 3.45) mm; p < 0.0001].
    Conclusions: The incidence of gangrenous cholecystitis is higher in COVID patients compared with non-COVID patients admitted to the emergency department with acute cholecystitis. Gangrenous cholecystitis in COVID patients is associated with high-grade Clavien-Dindo postoperative complications, longer hospital stay and higher mortality rate. The open cholecystectomy rate is higher in COVID compared with non -COVID patients. It is recommended to delay the surgical treatment in COVID patients, when it is possible, to decrease morbidity and mortality rates. COVID-19 infection and gangrenous cholecystistis are not absolute contraindications to perform laparoscopic cholecystectomy, in a case by case evaluation, in expert hands.
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2233734-9
    ISSN 1749-7922 ; 1749-7922
    ISSN (online) 1749-7922
    ISSN 1749-7922
    DOI 10.1186/s13017-022-00466-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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