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  1. Article ; Online: The weather condition and epidemics as triggers for febrile seizure: A single-center retrospective observational study.

    Kawakami, Isao / Inoue, Masataka / Adachi, Shunichi / Koga, Hiroshi

    Epilepsy & behavior : E&B

    2020  Volume 111, Page(s) 107306

    Abstract: Objective: The objective of this study was to investigate the association between the weather and epidemic condition and risk of febrile seizures (FSs) in Japan.: Study design: This single-center, retrospective study included 560 children (age, 6-60 ... ...

    Abstract Objective: The objective of this study was to investigate the association between the weather and epidemic condition and risk of febrile seizures (FSs) in Japan.
    Study design: This single-center, retrospective study included 560 children (age, 6-60 months) with FSs who were transported to our center by ambulance from January 2011 through December 2018. The weather (temperature, atmospheric pressure, relative air humidity, amount of rainfall, sunshine duration, and air concentration of nitrogen dioxide [NO
    Results: In the univariate analyses, neither daily or weekly weather condition nor weekly epidemic condition was correlated to FS transportation. Furthermore, the multiple logistic regression analysis suggested that epidemic influenza virus infection (odds ratio [OR], 1.34; 95% confidence interval [CI], 1.08-1.73) and infectious gastroenteritis (OR, 1.64; 95% CI, 1.09-2.54) were the independent risk factors for FS occurrence and weather condition was not associated with FS risk.
    Conclusions: Febrile seizure incidence may be increased by epidemic febrile infections but not by weather condition.
    MeSH term(s) Atmospheric Pressure ; Child, Preschool ; Epidemics/prevention & control ; Female ; Hot Temperature/adverse effects ; Humans ; Humidity/adverse effects ; Infant ; Japan/epidemiology ; Male ; Precipitating Factors ; Retrospective Studies ; Risk Factors ; Seizures, Febrile/epidemiology ; Seizures, Febrile/prevention & control ; Weather
    Language English
    Publishing date 2020-07-29
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2020.107306
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    Zs.A 5289: Show issues Location:
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  2. Article ; Online: Short-term neurodevelopmental outcomes of focal febrile seizures.

    Adachi, Shunichi / Inoue, Masataka / Kawakami, Isao / Koga, Hiroshi

    Brain & development

    2020  Volume 42, Issue 4, Page(s) 342–347

    Abstract: Objective: The effect of complex febrile seizures (FS), specifically focal FS, on long-term neurodevelopmental outcome is not well known. The aim of this study was to assess the association between complex FS and neurodevelopmental outcome.: Methods: ...

    Abstract Objective: The effect of complex febrile seizures (FS), specifically focal FS, on long-term neurodevelopmental outcome is not well known. The aim of this study was to assess the association between complex FS and neurodevelopmental outcome.
    Methods: A single-center, retrospective, cohort study was performed. The study included 282 children aged 6-60 months who experienced FS. Of these, 61 (22%) experienced recurrent FS, 33 (12%) prolonged FS, and 17 (6%) focal FS. The effect of these complex FS on subsequent need for special neurodevelopmental support was investigated. The neurodevelopmental status after FS was evaluated by a questionnaire.
    Results: During a median follow-up period of 3 years post FS, 12 children (4.3%) required special neurodevelopmental support. Univariate analysis demonstrated a significant association between focal FS and the need for subsequent special neurodevelopmental support, as well as a correlation between prolonged FS and pre-existing neurodevelopmental abnormality. Multiple logistic regression analysis demonstrated that focal FS (odds ratio [OR]: 12.27; 95% confidence interval [CI]: 2.11-71.22) and pre-existing neurodevelopmental abnormality (OR: 262; 95% CI: 17-3944) were significantly associated with the need for subsequent special support.
    Conclusion: An association was found between focal FS and subsequent neurodevelopmental impairment; therefore, close follow-up with particular attention to neurodevelopmental status is required for children who experience focal FS.
    MeSH term(s) Child Development ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Neurodevelopmental Disorders/epidemiology ; Neurodevelopmental Disorders/etiology ; Retrospective Studies ; Risk Factors ; Seizures, Febrile/complications ; Seizures, Febrile/epidemiology
    Language English
    Publishing date 2020-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 604822-5
    ISSN 1872-7131 ; 0387-7604
    ISSN (online) 1872-7131
    ISSN 0387-7604
    DOI 10.1016/j.braindev.2020.01.005
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    Zs.A 1788: Show issues Location:
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  3. Article ; Online: Rhabdomyolysis Associated With Primary Human Herpesvirus-6 Infection.

    Murakami, Ryunosuke / Adachi, Shunichi / Koga, Hiroshi

    The Pediatric infectious disease journal

    2019  Volume 38, Issue 12, Page(s) e341

    MeSH term(s) Herpesvirus 6, Human ; Humans ; Infant ; Rhabdomyolysis ; Roseolovirus Infections
    Language English
    Publishing date 2019-11-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002476
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    Zs.A 1852: Show issues Location:
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  4. Article ; Online: Change in the strategy for prophylactic diazepam use for febrile seizures and the impact on seizure recurrence within 24 h.

    Inoue, Masataka / Adachi, Shunichi / Kawakami, Isao / Koga, Hiroshi

    Seizure

    2019  Volume 75, Page(s) 70–74

    Abstract: Purpose: To investigate the association between reduced prophylactic diazepam usage and short-term recurrence of febrile seizures (FSs) after the FS practice guideline was updated in Japan.: Method: In this single-center, retrospective study, ... ...

    Abstract Purpose: To investigate the association between reduced prophylactic diazepam usage and short-term recurrence of febrile seizures (FSs) after the FS practice guideline was updated in Japan.
    Method: In this single-center, retrospective study, children (6-60 months of age) with FS who were transported to our center by ambulance from January 2011 through December 2018 were included. Rectal administration of diazepam (0.3-0.5 mg/kg) after the first seizure and seizure recurrence within 24 h were compared between 2011-2015 (pre-guideline revision) and 2016-2018 (post-guideline revision).
    Results: Among the total of 509 children, 297 were transported to our hospital in 2011-2015 and 212 in 2016-2018. Rectal diazepam administration was decreased in 2016-2018 (17 %) compared to 2011-2015 (53 %, P < 0.0001), while seizure recurrence was increased in 2016-2018 (20 %) compared to 2011-2015 (12 %, P = 0.0087). Similarly, hospital revisits (23 %) and hospital admissions (26 %) were increased in 2016-2018 compared to 2011-2015 (15 %, P = 0.031 and 18 %, P = 0.026, respectively). Multiple logistic regression analyses showed that prophylactic diazepam administration was the only factor related to preventing seizure recurrence. FS recurrence after the initial seizure was significantly less frequent with diazepam use (6 %) than without diazepam use (21 %, P < 0.0001; relative risk reduction, 70 %; number needed to treat, 6.8 children).
    Conclusion: The FS practice guideline revision was associated with reduced prophylactic diazepam usage and increased FS recurrence within 24 h in Japan. Prophylactic diazepam use should be determined based on clinical safety, local health infrastructure, and parental anxiety.
    MeSH term(s) Anticonvulsants/administration & dosage ; Child, Preschool ; Diazepam/administration & dosage ; Drug Administration Routes ; Female ; Humans ; Infant ; Japan/epidemiology ; Male ; Pre-Exposure Prophylaxis/methods ; Pre-Exposure Prophylaxis/trends ; Recurrence ; Retrospective Studies ; Seizures, Febrile/diagnosis ; Seizures, Febrile/drug therapy ; Seizures, Febrile/epidemiology ; Time Factors
    Chemical Substances Anticonvulsants ; Diazepam (Q3JTX2Q7TU)
    Language English
    Publishing date 2019-12-23
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2019.12.021
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3573: Show issues Location:
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  5. Article ; Online: Optimal biologics for juvenile idiopathic arthritis in an infection with SARS-CoV-2 α-variant.

    Adachi, Shunichi / Sonoda, Motoshi / Ishimura, Masataka / Eguchi, Katsuhide / Tanaka, Tamami / Motomura, Yoshitomo / Ohga, Shouichi

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2021  Volume 33, Issue 1, Page(s) e13686

    MeSH term(s) Antibodies, Monoclonal, Humanized ; Arthritis, Juvenile/drug therapy ; Biological Products/therapeutic use ; COVID-19 ; Child ; Female ; Humans ; SARS-CoV-2
    Chemical Substances Antibodies, Monoclonal, Humanized ; Biological Products
    Language English
    Publishing date 2021-11-06
    Publishing country England
    Document type Case Reports ; Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13686
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    Zs.A 3096: Show issues Location:
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  6. Article: Vitamin A deficiency–associated corneal perforation in a boy with autism spectrum disorder: A case report and literature review

    Adachi, Shunichi / Torio, Michiko / Okuzono, Sayaka / Motomura, Yoshitomo / Ichimiya, Yuko / Sonoda, Yuri / Nagata, Jyunya / Okamoto, Misato / Notomi, Shoji / Sanefuji, Masafumi / Sakai, Yasunari / Ohga, Shouichi

    Nutrition. 2021 Oct., v. 90

    2021  

    Abstract: Malnutrition and vitamin deficiency are growing concerns in the clinical management of children with autism spectrum disorder (ASD). This case report presents a boy with ASD who developed vitamin A deficiency during follow-up.A 7-y-old boy had been ... ...

    Abstract Malnutrition and vitamin deficiency are growing concerns in the clinical management of children with autism spectrum disorder (ASD). This case report presents a boy with ASD who developed vitamin A deficiency during follow-up.A 7-y-old boy had been diagnosed with ASD and developmental delay at age 18 mo. He developed convulsions associated with hypocalcemia and vitamin D deficiency at 3 y of age. Although vitamin D supplementation was continued, he was only able to eat rice, green tea, and fried potatoes from 3 y of age to age 7 y. He had started rubbing his eyes and had refused to open his eyes 9 mo before. An ophthalmologic examination showed bilateral corneal ulcers and right corneal perforation. Vitamin A was immediately supplemented with a nasogastric tube; however, his right eye was surgically enucleated against the persistent infection.A search of the relevant literature from 1993 to 2020 identified 11 cases of patients with ASD (5–17 y of age) who developed vitamin A deficiency owing to malnutrition. Only 4 cases (36%) had a full recovery in visual acuity.Vitamin A deficiency frequently causes irreversible visual impairment in children with ASD. Vigilant monitoring of vitamin levels prevents unfavorable outcomes in children with ASD and difficulty in food intake.
    Keywords autism ; boys ; case studies ; cornea ; food intake ; green tea ; hypocalcemia ; malnutrition ; rice ; vision disorders ; vitamin A ; vitamin A deficiency
    Language English
    Dates of publication 2021-10
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2021.111275
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Vitamin A deficiency-associated corneal perforation in a boy with autism spectrum disorder: A case report and literature review.

    Adachi, Shunichi / Torio, Michiko / Okuzono, Sayaka / Motomura, Yoshitomo / Ichimiya, Yuko / Sonoda, Yuri / Nagata, Jyunya / Okamoto, Misato / Notomi, Shoji / Sanefuji, Masafumi / Sakai, Yasunari / Ohga, Shouichi

    Nutrition (Burbank, Los Angeles County, Calif.)

    2021  Volume 90, Page(s) 111275

    Abstract: Background: Malnutrition and vitamin deficiency are growing concerns in the clinical management of children with autism spectrum disorder (ASD). This case report presents a boy with ASD who developed vitamin A deficiency during follow-up.: Case report! ...

    Abstract Background: Malnutrition and vitamin deficiency are growing concerns in the clinical management of children with autism spectrum disorder (ASD). This case report presents a boy with ASD who developed vitamin A deficiency during follow-up.
    Case report: A 7-y-old boy had been diagnosed with ASD and developmental delay at age 18 mo. He developed convulsions associated with hypocalcemia and vitamin D deficiency at 3 y of age. Although vitamin D supplementation was continued, he was only able to eat rice, green tea, and fried potatoes from 3 y of age to age 7 y. He had started rubbing his eyes and had refused to open his eyes 9 mo before. An ophthalmologic examination showed bilateral corneal ulcers and right corneal perforation. Vitamin A was immediately supplemented with a nasogastric tube; however, his right eye was surgically enucleated against the persistent infection.
    Literature review: A search of the relevant literature from 1993 to 2020 identified 11 cases of patients with ASD (5-17 y of age) who developed vitamin A deficiency owing to malnutrition. Only 4 cases (36%) had a full recovery in visual acuity.
    Conclusion: Vitamin A deficiency frequently causes irreversible visual impairment in children with ASD. Vigilant monitoring of vitamin levels prevents unfavorable outcomes in children with ASD and difficulty in food intake.
    MeSH term(s) Autism Spectrum Disorder/complications ; Child ; Corneal Perforation ; Dietary Supplements ; Humans ; Male ; Vitamin A Deficiency/complications ; Vitamin D Deficiency
    Language English
    Publishing date 2021-04-20
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2021.111275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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