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  1. Article: Iliacus Myositis and Bacteremia Caused by Non-typhoidal Salmonella in a Healthy Adult: A Case Report.

    Miyazaki, Yu / Adachi, Takuya

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52182

    Abstract: Typically, non- ... ...

    Abstract Typically, non-typhoidal
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Human mpox presenting with penile edema and ulcer: A case report.

    Miyazaki, Yu / Adachi, Takuya

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2024  

    Abstract: Human mpox, which has spread worldwide since May 2022, is characterized by symptoms involving the genital area; however, its treatment methods and clinical course are not completely understood. Furthermore, penile swelling in human mpox can be difficult ... ...

    Abstract Human mpox, which has spread worldwide since May 2022, is characterized by symptoms involving the genital area; however, its treatment methods and clinical course are not completely understood. Furthermore, penile swelling in human mpox can be difficult to differentiate from cellulitis and antibiotic use has been reported in such cases. Herein, we report a case of human mpox in Japan with prominent penile swelling and persistent penile ulcers that improved without specific treatment. The patient was a Japanese man in his 20s with a history of having sexual intercourse with men frequently. He visited Tokyo Metropolitan Toshima Hospital because of a fever and rash in the genital area. Physical examination revealed vesicles on the limbs, penile pigmentation, and significant penile swelling and redness. There were no signs of cellulitis and symptomatic treatment was initiated with outpatient follow-up. After 7 days, an improving trend in penile swelling, redness, and pain was observed. However, a partially black skin ulcer with exudate was observed at the left coronal sulcus of the penis. Therefore, the symptomatic treatment was continued. On illness day 28, the penile swelling completely improved; however, the penile ulcer and pain persisted, and the exudate was observed again. By illness day 63, the pain in his anogenital area had disappeared, and the penile skin ulcer had healed. The following observations were noted in this case: (i) human mpox can improve without specific treatment such as tecovirimat administration and (ii) skin lesions in the genital area may change over time.
    Language English
    Publishing date 2024-01-11
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2024.01.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Non-biomedical factors in the Ebola virus disease outbreak in West Africa.

    Adachi, Takuya

    Uirusu

    2015  Volume 65, Issue 1, Page(s) 83–88

    Abstract: The outbreak of Ebola virus disease, reported in West Africa in 2014, has become the largest ever one in the history. Tremendous efforts by all the parties concerned are now bringing this epidemic closer to the end, while observing a large number of ... ...

    Abstract The outbreak of Ebola virus disease, reported in West Africa in 2014, has become the largest ever one in the history. Tremendous efforts by all the parties concerned are now bringing this epidemic closer to the end, while observing a large number of cases and deaths, including health care workers.This paper features five questions:1. Why did it emerge in West Africa?2. Why has it spread so wide and intensely?3. Why were so many health care workers infected?4. Why is it being brought under control?5. Would it emerge and spread in Japan in the same way?Ebola virus transmits through human acts such as caregiving of the sick and attending a funeral, therefore an epidemic is not likely to subside naturally, but intentional interventions are needed to terminate its transmission. Who the outbreak response is meant for, either patients, the general public in the affected countries, or international communities, also determines its success or failure.
    MeSH term(s) Africa, Western/epidemiology ; Animals ; Disease Outbreaks ; Family ; Hemorrhagic Fever, Ebola/epidemiology ; Hemorrhagic Fever, Ebola/mortality ; Hemorrhagic Fever, Ebola/transmission ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Infectious Disease Transmission, Patient-to-Professional/statistics & numerical data ; Patient Care Team
    Language Japanese
    Publishing date 2015
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 603272-2
    ISSN 0042-6857
    ISSN 0042-6857
    DOI 10.2222/jsv.65.83
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A new type of simulated partial gravity apparatus for rats based on a pully-spring system.

    Zhang, Shenke / Adachi, Takuya / Zhang, Shengli / Yoshida, Yukari / Takahashi, Akihisa

    Frontiers in cell and developmental biology

    2022  Volume 10, Page(s) 965656

    Abstract: The return to the Moon and the landing on Mars has emphasized the need for greater attention to the effects of partial gravity on human health. Here, we sought to devise a new type of simulated partial gravity apparatus that could more efficiently and ... ...

    Abstract The return to the Moon and the landing on Mars has emphasized the need for greater attention to the effects of partial gravity on human health. Here, we sought to devise a new type of simulated partial gravity apparatus that could more efficiently and accurately provide a partial gravity environment for rat hindlimbs. The new apparatus uses a pulley system and tail suspension to create the simulated partial gravity of the rat's hind limbs by varying the weight in a balance container attached to the pulley system. An experiment was designed to verify the reliability and stability of the new apparatus. In this experiment, 25 seven-week-old male Wistar Hannover rats were randomly divided into five groups (
    Language English
    Publishing date 2022-08-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.965656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Accuracy Verification of Four-Dimensional CT Analysis of Knee Joint Movements: A Pilot Study Using a Knee Joint Model and Motion-Capture System.

    Adachi, Takuya / Kato, Yuki / Kiyotomo, Dai / Kawamukai, Katsushige / Takazawa, Shuzo / Suzuki, Takahiro / Machida, Youichi

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35616

    Abstract: Objective This study aimed to use the optical motion-capture method to verify the accuracy of four-dimensional computed tomography (4D-CT) analysis of knee joint movement. Methods One static CT and three 4D-CT examinations of the knee joint model were ... ...

    Abstract Objective This study aimed to use the optical motion-capture method to verify the accuracy of four-dimensional computed tomography (4D-CT) analysis of knee joint movement. Methods One static CT and three 4D-CT examinations of the knee joint model were obtained. The knee joint model was passively moved in the CT gantry during 4D-CT acquisitions. 4D-CT and static CT examinations were matched to perform 3D-3D registration. An optical-motion capture system recorded the position-posture of the knee joint model simultaneously with the 4D-CT acquisitions. Reference axes (X, Y, and Z directions) were defined based on static CT and applied to 4D-CT and the optical-motion capture system. Using the position-posture of the motion capture system as a reference standard, the position-posture measurements using 4D-CT were compared to these values, and the accuracy of the 4D-CT analysis of knee joint movements was quantitatively assessed. Results The position-posture measurements obtained from 4D-CT showed a similar tendency to those obtained from the motion-capture system. In the femorotibial joint, the difference in the spatial orientation between the two measurements was 0.7 mm in the X direction, 0.9 mm in the Y direction, and 2.8 mm in the Z direction. The difference in angle was 1.9° in the varus/valgus direction, 1.1° in the internal/external rotation, and 1.8° in extension/flexion. In the patellofemoral joint, the difference between the two measurements was 0.9 mm in the X direction, 1.3 mm in the Y direction, and 1.2 mm in the Z direction. The difference in angle was 0.9° for varus/valgus, 1.1° for internal/external rotation, and 1.3° for extension/flexion. Conclusions 4D-CT with 3D-3D registration could record the position-posture of knee joint movements with an error of less than 3 mm and less than 2° when compared with the highly accurate optical-motion capture system. Knee joint movement analysis using 4D-CT with 3D-3D registration showed excellent accuracy for in vivo applications.
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Noteworthy performance of muscle injured para-athletes: A study of MRI-detected muscle injuries at the Tokyo 2020 Summer Paralympic Games.

    Katagiri, Hiroki / Forster, Bruce B / Koga, Hideyuki / An, Jae-Sung / Adachi, Takuya / Derman, Wayne

    American journal of physical medicine & rehabilitation

    2023  

    Abstract: Background: To the best of our knowledge, no studies have attempted to correlate athletic performance with muscle injuries sustained during Paralympic Games.: Aim: This study reports the incidence, anatomical location, anatomical site classification, ...

    Abstract Background: To the best of our knowledge, no studies have attempted to correlate athletic performance with muscle injuries sustained during Paralympic Games.
    Aim: This study reports the incidence, anatomical location, anatomical site classification, and relationship between competition results and anatomical site classification in athletes who participated in the Paralympic Games.
    Methods: All MRI images collected at the IPC polyclinic at the Tokyo 2020 Paralympic Games were reviewed to identify the presence and anatomical site of muscle injuries. The athletes' competition results were reviewed using IPC data sources.
    Results: Twenty-six MRI-detected muscle injuries were observed in 16 male and 10 female athletes. Muscle injuries were most commonly observed during track and field events (n = 20) and in athletes with visual impairment (n = 12). Ten of the injuries involved the tendon. Twenty-one of injured athletes (81%) completed their competition, whereas 5 athletes did not. Eight athletes won medals in the Games. The anatomical site of muscle injury did not significantly impact the proportion of athletes who did not finish competition.
    Conclusion: Many athletes who sustained muscle injuries completed their competitions. No association was found between anatomical site classification and Paralympic athletes' performance in this study.
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219390-5
    ISSN 1537-7385 ; 0002-9491 ; 0894-9115
    ISSN (online) 1537-7385
    ISSN 0002-9491 ; 0894-9115
    DOI 10.1097/PHM.0000000000002367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effects of Denture Treatment on Salivary Metabolites: A Pilot Study.

    Ichigaya, Narumi / Kawanishi, Norishige / Adachi, Takuya / Sugimoto, Masahiro / Kimoto, Katsuhiko / Hoshi, Noriyuki

    International journal of molecular sciences

    2023  Volume 24, Issue 18

    Abstract: Symptoms of oral discomfort such as dry mouth are common in older people wearing dentures. Such symptoms are mainly treated symptomatically. Many of these symptoms are related to saliva, and associations with salivary volume have been reported. Although ... ...

    Abstract Symptoms of oral discomfort such as dry mouth are common in older people wearing dentures. Such symptoms are mainly treated symptomatically. Many of these symptoms are related to saliva, and associations with salivary volume have been reported. Although denture treatment improves symptoms by increasing the amount of saliva, the effects on salivary components remain unclear. This study aimed to investigate the effects of denture treatment on salivary metabolite changes based on salivary metabolome analyses. We enrolled 21 patients requiring denture treatment. At the first visit, and after completion of denture treatment, saliva outflow was measured under resting and stimulated conditions, samples for salivary metabolite analysis were collected, and masticatory efficiency was tested. In all participants, masticatory efficiency increased after denture treatment. Moreover, the amounts of resting and stimulated saliva were increased. Using salivary metabolome analysis, 61 salivary metabolites were detected. Substantial concentration changes were observed for 4 and 21 metabolites in resting and stimulated saliva, respectively. The four metabolites common to both saliva tests had significantly lower concentrations after treatment. These results suggest that the improvement in masticatory function by dentures is related not only to salivary secretion volume, but also to salivary metabolite composition.
    MeSH term(s) Humans ; Aged ; Pilot Projects ; Metabolome ; Rest ; Saliva ; Dentures
    Language English
    Publishing date 2023-09-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241813959
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  8. Article ; Online: Fluorodeoxyglucose positron emission tomography/computed tomography findings after percutaneous cryoablation of early breast cancer.

    Adachi, Takuya / Machida, Youichi / Fukuma, Eisuke / Tateishi, Ukihide

    Cancer imaging : the official publication of the International Cancer Imaging Society

    2020  Volume 20, Issue 1, Page(s) 49

    Abstract: Background: To document : Methods: Data of 193 consecutive patients who had undergone cryoablation for invasive ductal carcinoma or ductal carcinoma in situ ≤ 15 mm without a history of ipsilateral breast cancer, synchronous ipsilateral lesion, and ... ...

    Abstract Background: To document
    Methods: Data of 193 consecutive patients who had undergone cryoablation for invasive ductal carcinoma or ductal carcinoma in situ ≤ 15 mm without a history of ipsilateral breast cancer, synchronous ipsilateral lesion, and with estrogen receptor positive/human epidermal growth factor 2 negative were enrolled. The imaging characteristics of the treated areas were evaluated and classified on CT images as one of two types: fatty mass or non-fatty mass type. The maximum standardized uptake value (SUVmax) of the initial post-cryoablation PET/CT, the CT type of the treated area and selected clinical factors (age, menopausal status, lesion area, breast density, timing of PET/CT) were retrospectively evaluated.
    Results: The median interval between cryoablation and the initial post-cryoablation PET/CT was 12 months. The median SUVmax of the treated area was 1.36. The CT findings of the treated area were classified as fatty mass type (n = 137, 71.0%) or non-fatty mass type (n = 56, 29.0%). The treated areas of patients with lower breast density, of older age, post-menopausal status, and lower radiation dose were significantly more likely to be of fatty mass type (P < 0.001). Non-fatty mass type averaged a significantly higher SUVmax than did fatty mass type.
    Conclusions: Post-cryoablation PET/CT findings are of fatty or non-fatty mass type. A non-fatty appearance, which can show higher SUVmax, does not necessarily denote recurrence.
    MeSH term(s) Adult ; Aged ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/surgery ; Cryosurgery/adverse effects ; Cryosurgery/methods ; Female ; Fluorodeoxyglucose F18 ; Humans ; Middle Aged ; Neoplasm Recurrence, Local/diagnostic imaging ; Positron Emission Tomography Computed Tomography/methods ; Positron Emission Tomography Computed Tomography/standards ; Postoperative Complications/diagnostic imaging ; Radiopharmaceuticals
    Chemical Substances Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2104862-9
    ISSN 1470-7330 ; 1470-7330
    ISSN (online) 1470-7330
    ISSN 1470-7330
    DOI 10.1186/s40644-020-00325-y
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  9. Article ; Online: Zoning inside the renal fascia: The anatomical relationship between the urinary system and perirenal fat.

    Ochi, Atsuhiko / Muro, Satoru / Adachi, Takuya / Akita, Keiichi

    International journal of urology : official journal of the Japanese Urological Association

    2020  Volume 27, Issue 7, Page(s) 625–633

    Abstract: Objectives: To examine the anatomical relationship between the urinary system and perirenal fat, and to clarify the zoning inside the renal fascia.: Methods: Using computed tomography images from 50 men, we examined perinephric veins to reveal vessel ...

    Abstract Objectives: To examine the anatomical relationship between the urinary system and perirenal fat, and to clarify the zoning inside the renal fascia.
    Methods: Using computed tomography images from 50 men, we examined perinephric veins to reveal vessel communication in perirenal fat. Nine cadavers were dissected to investigate connective tissue continuity and vessel communication inside the renal fascia. Eight retroperitoneal specimens were macroscopically observed: four from the anterior and four from the posterior aspects. One specimen was used to obtain retroperitoneal transverse sections to study macroscopic anatomy and histology.
    Results: Perinephric veins were classified into four types (superior, middle, inferior and lateral) using computed tomography. Most of the inferior perinephric veins were connected to the ipsilateral gonadal vein. In the cadaveric study, the superior and middle perinephric veins communicated with veins deriving from the ipsilateral adrenal gland. A fibrous connective tissue gap between perirenal fat and renal hilar fat was observed in posterior aspect dissection. From the gap, we could dissect the urinary system from perirenal fat en bloc along with a thin fibrous connective tissue layer. Communicating vessels between perirenal fat and the urinary system were rare.
    Conclusions: Our results suggest that perirenal fat belongs to the connective tissue of the gonad and the adrenal gland. The urinary system is separate from perirenal fat, and is located on the dorsal side inside the renal fascia. This concept of zoning inside the renal fascia is valuable particularly in retroperitoneoscopic donor nephrectomy.
    MeSH term(s) Fascia/diagnostic imaging ; Humans ; Kidney/diagnostic imaging ; Kidney Neoplasms/surgery ; Male ; Nephrectomy ; Retroperitoneal Space/diagnostic imaging
    Language English
    Publishing date 2020-04-20
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1328401-0
    ISSN 1442-2042 ; 0919-8172
    ISSN (online) 1442-2042
    ISSN 0919-8172
    DOI 10.1111/iju.14248
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  10. Article: Positive Effects of Saliva on Oral Candidiasis: Basic Research on the Analysis of Salivary Properties.

    Kawanishi, Norishige / Hoshi, Noriyuki / Adachi, Takuya / Ichigaya, Narumi / Kimoto, Katsuhiko

    Journal of clinical medicine

    2021  Volume 10, Issue 4

    Abstract: The major causes of oral candidiasis include decreased salivary flow rate and the use of ill-fitting dentures. However, the relationships among prosthetic treatment, saliva, ... ...

    Abstract The major causes of oral candidiasis include decreased salivary flow rate and the use of ill-fitting dentures. However, the relationships among prosthetic treatment, saliva, and
    Language English
    Publishing date 2021-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10040812
    Database MEDical Literature Analysis and Retrieval System OnLINE

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