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  1. Book ; Thesis: Konventionelle versus pathogeninaktivierte Thrombozytenkonzentrate bei perioperativer Koagulopathie

    Adam, Elisabeth

    2013  

    Author's details vorgelegt von Elisabeth Adam
    Language German
    Size 82 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2014
    HBZ-ID HT018390754
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 D 701 order for loan Magazin

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  2. Book: Erfahrungsschatz Notfallmedizin

    Adam, Elisabeth / Weber, Christian Friedrich

    100 kritische Ereignisse, Fehler und Komplikationen

    2019  

    Author's details herausgegeben von Christian Friedrich Weber [und 7 anderen] ; unter Mitarbeit von Elisabeth Adam [und vielen weiteren]
    Keywords Notfallmedizin
    Subject Internistische Notfallmedizin
    Language German
    Size Illustrationen
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Accompanying material Zugang zu Online-Version in der eRef über Code
    HBZ-ID HT019865504
    ISBN 978-3-13-241543-0 ; 3-13-241543-X ; 9783132415447 ; 9783132415454 ; 3132415448 ; 3132415456
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 1700 available for loan (reading room) Lesesaal EG
    Zugang zu zusätzlichem Internetmaterial über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  3. Book: Fehler und Irrtümer in der Anästhesie

    Adam, Elisabeth / Meybohm, Patrick / St. Pierre, Michael / Heinrichs, Wolfgang / Bein, Berthold Helmut

    2017  

    Author's details herausgegeben von Patrick Meybohm, Michael St.Pierre, Wolfgang Heinrichs, Berthold Bein ; unter Mitarbeit von Elisabeth Adam [und 19 weiteren]
    Keywords Narkosezwischenfall
    Subject Narkosebedingte Komplikation ; Anästhesiebedingte Komplikation ; Anästhesie ; Narkose
    Language German
    Size 287 Seiten, Illustrationen, 24 cm x 17 cm
    Edition 2., aktualisierte Auflage
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Publishing country Germany
    Document type Book
    Note Zugang zu Online-Ausgabe über Code und QR-Code
    HBZ-ID HT019153612
    ISBN 978-3-13-162982-1 ; 3-13-162982-7 ; 9783132027527 ; 9783131629920 ; 3132027529 ; 3131629924
    DOI 10.1055/b-004-132255
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 1815 available for loan (reading room) Lesesaal EG
    Zugang zu Online-Ausgabe über Code und QR-Code aus lizenzrechtlichen Gründen nicht verfügbar
    2020 A 1405 available for loan (reading room) Lesesaal EG

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  4. Article: Plasma Transfusion Practice in Adult Surgical Patients: Systematic Review of the Literature.

    Adam, Elisabeth Hannah / Fischer, Dania

    Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

    2020  Volume 47, Issue 5, Page(s) 347–359

    Abstract: Background: Plasma transfusions are most commonly used therapeutically for bleeding or prophylactically in non-bleeding patients prior to invasive procedures or surgery. Although plasma transfusions generally seem to decline, plasma usage for ... ...

    Abstract Background: Plasma transfusions are most commonly used therapeutically for bleeding or prophylactically in non-bleeding patients prior to invasive procedures or surgery. Although plasma transfusions generally seem to decline, plasma usage for indications that lack evidence of efficacy prevail.
    Summary: There is wide international, interinstitutional, and interindividual variance regarding the compliance with guidelines based on published references, supported by appropriate testing. There is furthermore a profound lack of evidence from randomized controlled trials comparing the effect of plasma transfusion with that of other therapeutic interventions for most indications, including massive bleeding. The expected benefit of a plasma transfusion needs to be balanced carefully against the associated risk of adverse events. In light of the heterogeneous nature of bleeding conditions and their rapid evolvement over time, fibrinogen and factor concentrate therapy, directed at specific phases of coagulation identified by alternative laboratory assays, may offer advantages over conventional blood product ratio-driven resuscitation. However, their outcome benefit has not been demonstrated in well-powered prospective trials. This systematic review will detail the current evidence base for plasma transfusion in adult surgical patients.
    Language English
    Publishing date 2020-09-18
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000511271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 959: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Perthes-Syndrom nach Überrolltrauma.

    Tanner, Linda / Zabel, Julian / Zacharowski, Kai / Adam, Elisabeth

    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS

    2021  Volume 56, Issue 2, Page(s) 135–140

    Abstract: Roll-over trauma and associated traumatic entrapments frequently result in serious polytraumatisation. In rare cases, severe extrathoracic compressions and a protracted entrapment period can lead to Perthes syndrome, also known as traumatic asphyxia. The ...

    Title translation Perthes Syndrome after Roll-Over Trauma.
    Abstract Roll-over trauma and associated traumatic entrapments frequently result in serious polytraumatisation. In rare cases, severe extrathoracic compressions and a protracted entrapment period can lead to Perthes syndrome, also known as traumatic asphyxia. The Perthes syndrome manifests itself by a triad of craniocervical cyanosis, facial petechiae and subconjunctival haemorrhages, enabling a rapid diagnosis based on these typical clinical features. In addition, a contusion of the heart, lungs or even the liver may occur as well as neurological and other ophthalmological complications. An early identification of this condition, the elevation of the upper body to allow adequate venous drainage in addition to ensuring sufficient oxygenation are essential for optimal therapy. In general, no long-term complications are to be expected for Perthes syndrome. The stasis usually disappears completely within a few months.
    MeSH term(s) Asphyxia ; Face ; Humans ; Purpura ; Syndrome ; Thoracic Injuries
    Language German
    Publishing date 2021-02-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1065682-0
    ISSN 1439-1074 ; 0939-2661
    ISSN (online) 1439-1074
    ISSN 0939-2661
    DOI 10.1055/a-1299-0546
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 257: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 96: Show issues
    Zs.A 257/X: Show issues Location:
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  6. Article ; Online: Moths sense but do not learn flower odors with their proboscis during flower investigation.

    Adam, Elisabeth / Hansson, Bill S / Knaden, Markus

    The Journal of experimental biology

    2021  Volume 224, Issue 17

    Abstract: Insect pollinators, such as the tobacco hawkmoth Manduca sexta, are known for locating flowers and learning floral odors by using their antennae. A recent study revealed, however, that the tobacco hawkmoth additionally possesses olfactory sensilla at the ...

    Abstract Insect pollinators, such as the tobacco hawkmoth Manduca sexta, are known for locating flowers and learning floral odors by using their antennae. A recent study revealed, however, that the tobacco hawkmoth additionally possesses olfactory sensilla at the tip of its proboscis. Here, we asked whether this second 'nose' of the hawkmoth is involved in odor learning, similar to the antennae. We first show that M. sexta foraging efficiency at Nicotiana attenuata flowers increases with experience. This raises the question whether olfactory learning with the proboscis plays a role during flower handling. By rewarding the moths at an artificial flower, we show that, although moths learn an odor easily when they perceive it with their antennae, experiencing the odor just with the proboscis is not sufficient for odor learning. Furthermore, experiencing the odor with the antennae during training does not affect the behavior of the moths when they later detect the learned odor with the proboscis only. Therefore, there seems to be no cross-talk between the antennae and proboscis, and information learnt by the antennae cannot be retrieved by the proboscis.
    MeSH term(s) Animals ; Flowers ; Learning ; Manduca ; Moths ; Odorants
    Language English
    Publishing date 2021-09-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.242780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2629: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: No Sequestration of Commonly Used Anti-Infectives in the Extracorporeal Membrane Oxygenation (ECMO) Circuit-An Ex Vivo Study.

    Booke, Hendrik / Friedrichson, Benjamin / Draheim, Lena / von Groote, Thilo Caspar / Frey, Otto / Röhr, Anka / Zacharowski, Kai / Adam, Elisabeth Hannah

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 4

    Abstract: Patients undergoing extracorporeal membrane oxygenation (ECMO) often require therapy with anti-infective drugs. The pharmacokinetics of these drugs may be altered during ECMO treatment due to pathophysiological changes in the drug metabolism of the ... ...

    Abstract Patients undergoing extracorporeal membrane oxygenation (ECMO) often require therapy with anti-infective drugs. The pharmacokinetics of these drugs may be altered during ECMO treatment due to pathophysiological changes in the drug metabolism of the critically ill and/or the ECMO therapy itself. This study investigates the latter aspect for commonly used anti-infective drugs in an ex vivo setting. A fully functional ECMO device circulated an albumin-electrolyte solution through the ECMO tubes and oxygenator. The antibiotic agents cefazolin, cefuroxim, cefepime, cefiderocol, linezolid and daptomycin and the antifungal agent anidulafungin were added. Blood samples were taken over a period of four hours and drug concentrations were measured via high-pressure liquid chromatography (HPLC) with UV detection. Subsequently, the study analyzed the time course of anti-infective concentrations. The results showed no significant changes in the concentration of any tested anti-infectives throughout the study period. This ex vivo study demonstrates that the ECMO device itself has no impact on the concentration of commonly used anti-infectives. These findings suggest that ECMO therapy does not contribute to alterations in the concentrations of anti-infective medications in severely ill patients.
    Language English
    Publishing date 2024-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13040373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial.

    Flinspach, Armin Niklas / Raimann, Florian Jürgen / Kaiser, Philipp / Pfaff, Michaela / Zacharowski, Kai / Neef, Vanessa / Adam, Elisabeth Hannah

    Critical care (London, England)

    2024  Volume 28, Issue 1, Page(s) 111

    Abstract: Background: Optimal intensive care of patients undergoing valve surgery is a complex balancing act between sedation for monitoring and timely postoperative awakening. It remains unclear, if these requirements can be fulfilled by volatile sedations in ... ...

    Abstract Background: Optimal intensive care of patients undergoing valve surgery is a complex balancing act between sedation for monitoring and timely postoperative awakening. It remains unclear, if these requirements can be fulfilled by volatile sedations in intensive care medicine in an efficient manner. Therefore, this study aimed to assess the time to extubation and secondary the workload required.
    Methods: We conducted a prospective randomized single-center trial at a tertiary university hospital to evaluate the postoperative management of open valve surgery patients. The study was randomized with regard to the use of volatile sedation compared to propofol sedation. Sedation was discontinued 60 min after admission for critical postoperative monitoring.
    Results: We observed a significantly earlier extubation (91 ± 39 min vs. 167 ± 77 min; p < 0.001), eye-opening (86 ± 28 min vs. 151 ± 71 min; p < 0.001) and command compliance (93 ± 38 min vs. 164 ± 75 min; p < 0.001) using volatile sedation, which in turn was associated with a significantly increased workload of a median of 9:56 min (± 4:16 min) set-up time. We did not observe any differences in complications. Cardiopulmonary bypass time did not differ between the groups 101 (IQR 81; 113) versus 112 (IQR 79; 136) minutes p = 0.36.
    Conclusions: Using volatile sedation is associated with few minutes additional workload in assembling and enables a significantly accelerated evaluation of vulnerable patient groups. Volatile sedation has considerable advantages and emerges as a safe sedation technique in our vulnerable study population.
    Trial registration: Clinical trials registration (NCT04958668) was completed on 1 July 2021.
    MeSH term(s) Humans ; Propofol/therapeutic use ; Prospective Studies ; Cardiac Surgical Procedures/methods ; Critical Care/methods ; Airway Extubation ; Hypnotics and Sedatives/therapeutic use
    Chemical Substances Propofol (YI7VU623SF) ; Hypnotics and Sedatives
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-024-04899-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Cardiopulmonary resuscitation in veno-venous-ECMO patients-A retrospective study on incidence, causes and outcome.

    Booke, Hendrik / Zacharowski, Kai / Adam, Elisabeth Hannah / Raimann, Florian Jürgen / Bauer, Frederike / Flinspach, Armin Niklas

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0290083

    Abstract: Introduction: Cardiac arrest in a modern intensive care unit (ICU) is associated with poor outcome although optimal resources are present at all times. Data on cardiac arrest (CA) of the increasing cohort of patients with veno-venous-extracorporeal ... ...

    Abstract Introduction: Cardiac arrest in a modern intensive care unit (ICU) is associated with poor outcome although optimal resources are present at all times. Data on cardiac arrest (CA) of the increasing cohort of patients with veno-venous-extracorporeal membrane oxygenation (VV-ECMO) are not available. Due to the highly invasive nature of this procedure, other incidences and causes of cardiac arrest are expected when compared to the ICU population without ECMO. This study focuses on cardiac arrest under VV-ECMO treatment.
    Methods: Retrospective single-center observational study including all VV-ECMO patients from 1st January 2019 until 31st March 2022. Primary focus of this study was number and causes for CA during VV-ECMO treatment. Secondary endpoints were treatment procedure, complications and outcome.
    Results: 140 patients were treated with VV-ECMO in the study period. Of those, 23 patients had 29 CA with need for cardiopulmonary resuscitation (CPR) during VV-ECMO treatment. Nearly half of all CA (48%; n = 14) occurred during medical procedures and 21% (n = 6) were device related. Pulseless electric activity (PEA) was the most common rhythm upon CPR initiation (72%). ROSC was achieved in 86%, two CA (6.9%) resulted in extracorporeal CPR. Survival to hospital discharge was 13% following CPR.
    Conclusion: CA occurs in over 15% of all patients treated with a VV-ECMO. Medical procedures during VV-ECMO are associated with a high risk of CA and should be planned with care. Also, the rate of ROSC was very high, only a small number of patients survived the overall VV-ECMO treatment course.
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0290083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Thesis: Antioxidantien vor und nach körperlicher Belastung

    Weimer-Adam, Elisabeth Judith

    ein Vergleich zwischen trainierten und untrainierten Probanden

    1999  

    Author's details vorgelegt von Elisabeth Judith Weimer-Adam, geb. Weimer
    Language German
    Size 116 S., graph. Darst., 21 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 1999 (Nur beschränkt für den Austausch)
    HBZ-ID HT012892304
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 D 157 order for loan Magazin

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