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  1. Book ; Online: A Maritime Archaeology of Ships

    Adams, J. R

    Innovation and Social Change in Late Medieval and Early Modern Europe

    2013  

    Abstract: In the last fifty years the investigation of maritime archaeological sites in the sea, in the coastal zone and in their interconnecting locales, has emerged as one of archaeology's most dynamic and fast developing fields. No longer a niche interest, ... ...

    Abstract In the last fifty years the investigation of maritime archaeological sites in the sea, in the coastal zone and in their interconnecting locales, has emerged as one of archaeology's most dynamic and fast developing fields. No longer a niche interest, maritime archaeology is recognised as having central relevance in the integrated study of the human past. Within maritime archaeology the study of watercraft has been understandably prominent and yet their potential is far from exhausted. In this book Jon Adams evaluates key episodes of technical change in the ways that ships were conceived, design
    Language English
    Size Online-Ressource (647 p)
    Publisher Oxbow Books
    Publishing place Havertown
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781842172971 ; 1842172972
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Application of linear response theory to magnetotransport properties of dense plasmas.

    Adams, J R / Reinholz, H / Redmer, R

    Physical review. E, Statistical, nonlinear, and soft matter physics

    2010  Volume 81, Issue 3 Pt 2, Page(s) 36409

    Abstract: Linear response theory, as developed within the Zubarev formalism, is a quantum statistical approach for describing systems out of but close to equilibrium, which has been successfully applied to a wide variety of plasmas in an external electric field ... ...

    Abstract Linear response theory, as developed within the Zubarev formalism, is a quantum statistical approach for describing systems out of but close to equilibrium, which has been successfully applied to a wide variety of plasmas in an external electric field and/or containing a temperature gradient. We present here an extension of linear response theory to include the effects of an external magnetic field. General expressions for the complete set of relevant transport properties are given. In particular, the Hall effect and the influence of a magnetic field on the dc electrical conductivity are discussed. Low-density limits including electron-electron scattering are presented as well as results for arbitrary degeneracy.
    Language English
    Publishing date 2010-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1550-2376
    ISSN (online) 1550-2376
    DOI 10.1103/PhysRevE.81.036409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Synthesis and functionalization of virus-mimicking cationic block copolymers with pathogen-associated carbohydrates as potential vaccine adjuvants

    Adams, J. R / Goswami, M / Mallapragada, S. K / Pohl, N. L. B

    RSC advances. 2014 Mar. 27, v. 4, no. 30

    2014  

    Abstract: We report the synthesis of a family of amphiphilic pentablock polymers with different cationic blocks and with controlled architectures as potential vaccine carriers for subunit vaccines. The temperature and pH-dependent micellization and gelation of ... ...

    Abstract We report the synthesis of a family of amphiphilic pentablock polymers with different cationic blocks and with controlled architectures as potential vaccine carriers for subunit vaccines. The temperature and pH-dependent micellization and gelation of these pentablock copolymers can provide a depot for sustained protein and gene delivery. The amphiphilic central triblock promotes cellular endocytosis, good gene delivery and has been used effectively as a vaccine adjuvant. The pentablock copolymer outer blocks condense DNA spontaneously as a result of electrostatic interactions for sustained combinational therapy. This family of polymers with different cationic groups was evaluated based on DNA complexation-ability and cytotoxicity to select promising candidates as DNA-based subunit vaccine adjuvants. Modification of other polymer systems with carbohydrates like mannose has been shown to enhance immunogenicity by activating pattern recognition receptors on antigen presenting cells and increasing uptake in these cells. Here, we report the synthesis of a virus-mimicking pentablock copolymer vaccine platform by successful functionalization of these polymers with mannose through an azide–alkyne Huisgen cycloaddition. The synthesis of a mannoside with the alkyne linker was achieved by a recently reported bismuth(v)-mediated activation of a thioglycoside that proved to leave the alkyne intact. The carbohydrate modification was shown not to interfere with the ability of these virus-mimicking block copolymers to complex DNA, thereby making this family of modified materials promising candidates for DNA-based vaccine delivery.
    Keywords alkynes ; antigen-presenting cells ; bismuth ; composite polymers ; cycloaddition reactions ; cytotoxicity ; DNA ; electrostatic interactions ; endocytosis ; gelation ; gene transfer ; immunogenicity ; mannose ; pH ; receptors ; subunit vaccines ; temperature ; therapeutics ; vaccine adjuvants
    Language English
    Dates of publication 2014-0327
    Size p. 15655-15663.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c3ra47687a
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Adenocarcinoma in ectopic prostatic tissue.

    Adams, J R

    The Journal of urology

    1993  Volume 150, Issue 4, Page(s) 1253–1254

    MeSH term(s) Adenocarcinoma/pathology ; Aged ; Choristoma/pathology ; Humans ; Male ; Prostate ; Prostatic Neoplasms/pathology ; Rectal Neoplasms/pathology
    Language English
    Publishing date 1993-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/s0022-5347(17)35747-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 331: Show issues

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  5. Article: The management of terminally ill patients.

    Adams, J R

    The Medical journal of Australia

    1992  Volume 157, Issue 10, Page(s) 715

    MeSH term(s) Euthanasia, Passive ; Humans ; Patient Advocacy ; Terminal Care
    Language English
    Publishing date 1992-11-16
    Publishing country Australia
    Document type Comment ; Letter
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Evaluating the efficacy of non-invasive genetic methods and estimating wolf survival during a ten-year period

    Marucco, F / Vucetich, L. M / Peterson, R. O / Adams, J. R / Vucetich, J. A

    Conservation genetics. 2012 Dec., v. 13, no. 6

    2012  

    Abstract: Genetic capture–recapture (CR) analysis is a highly promising tool to estimate population parameters and monitor populations through time. However, its level of accuracy has rarely been assessed and comparisons with traditional estimates in controlled ... ...

    Abstract Genetic capture–recapture (CR) analysis is a highly promising tool to estimate population parameters and monitor populations through time. However, its level of accuracy has rarely been assessed and comparisons with traditional estimates in controlled settings have rarely been performed. We used CR analysis with long-term fecal genotyping data and applied open-population models to estimate survival rates and assess trend in abundance of wolves in Isle Royale over 10 years, while simultaneously estimating those parameters with traditional aerial-based techniques that are believed to be reasonably accurate. Comparison of the techniques indicated that there is a good correspondence of estimates only when the effort in genetic sampling is high, which guarantees a high recapture probability. Juvenile wolves had higher annual CR survival rates than adult wolves; kill rates most affected wolf survival in this natural ecosystem, and higher annual kill rates were correlated with higher annual adult survival. Adult survival (but not juvenile survival) was an important predictor of population growth rate. Hence, we show that kill rates indirectly affected population growth rate and directly affected adult survival rate. These reliable estimates of survival have unique value because the Isle Royale wolf population is not exposed to any human-caused mortality. Therefore, knowing long-term patterns of annual survival and its relationship to population growth rate for a not hunted wolf population represents a critical baseline for wolf conservation throughout its worldwide distribution.
    Keywords adults ; ecosystems ; genotyping ; models ; population growth ; probability ; survival rate ; wolves
    Language English
    Dates of publication 2012-12
    Size p. 1611-1622.
    Publishing place Springer-Verlag
    Document type Article
    ZDB-ID 2059560-8
    ISSN 1572-9737 ; 1566-0621
    ISSN (online) 1572-9737
    ISSN 1566-0621
    DOI 10.1007/s10592-012-0412-4
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Assessing the quality of clinical trials: can it be done?

    Bennett, C L / Adams, J R

    Current oncology reports

    2001  Volume 3, Issue 5, Page(s) 387–388

    MeSH term(s) Anticoagulants/therapeutic use ; Clinical Trials as Topic/standards ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Meta-Analysis as Topic ; Research Design/standards
    Chemical Substances Anticoagulants ; Heparin, Low-Molecular-Weight
    Language English
    Publishing date 2001-07-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 2057359-5
    ISSN 1523-3790
    ISSN 1523-3790
    DOI 10.1007/s11912-001-0023-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5521: Show issues Location:
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  8. Article ; Online: TMJ dislocation.

    Nusrath, M A / Adams, J R / Farr, D R / Bryant, D G

    British dental journal

    2008  Volume 204, Issue 4, Page(s) 170–171

    MeSH term(s) Adult ; Anesthesia, Dental/adverse effects ; Anesthesia, Dental/methods ; Humans ; Joint Dislocations/etiology ; Male ; Nerve Block/adverse effects ; Temporomandibular Joint Disorders/etiology
    Language English
    Publishing date 2008-02-23
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/bdj.2008.112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Vulvar fusion.

    NOWLIN, P / ADAMS, J R / NALLE, B C

    The Journal of urology

    2004  Volume 62, Issue 1, Page(s) 75–79

    MeSH term(s) Female ; Humans ; Vulva/abnormalities
    Language English
    Publishing date 2004-06-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/S0022-5347(17)68890-6
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  10. Article: Functional imaging in Tourette's syndrome.

    Adams, J R / Troiano, A R / Calne, D B

    Journal of neural transmission (Vienna, Austria : 1996)

    2004  Volume 111, Issue 10-11, Page(s) 1495–1506

    Abstract: The cause or causes of Tourette's syndrome (TS) remain unknown. Functional imaging studies have evaluated several implicated neurotransmitter systems and focused predominantly on the frequency or severity of tics. The results have been inconclusive and ... ...

    Abstract The cause or causes of Tourette's syndrome (TS) remain unknown. Functional imaging studies have evaluated several implicated neurotransmitter systems and focused predominantly on the frequency or severity of tics. The results have been inconclusive and frequently contradictory with little light shed on pathogenetic mechanisms. However, metabolic derangements have been demonstrated within regions of the basal ganglia, limbic system and sensori-motor cortex and are in keeping with the concept of TS as both a motor and behavioral disorder. TS has long been regarded an involuntary movement disorder. However, many patients have stated that without the premonitory sensation, there would be no tics. For this reason, it has been suggested that the premonitory urge may be considered the involuntary component of TS and the performance of the tic merely a voluntary response. Future studies are needed to differentiate functional changes relating to urge from those associated with the performance of tics and tic suppression.
    MeSH term(s) Brain Chemistry/physiology ; Cerebrovascular Circulation ; Humans ; Magnetic Resonance Imaging ; Neurotransmitter Agents/metabolism ; Radionuclide Imaging ; Receptors, Neurotransmitter/metabolism ; Tourette Syndrome/diagnostic imaging ; Tourette Syndrome/metabolism ; Tourette Syndrome/pathology
    Chemical Substances Neurotransmitter Agents ; Receptors, Neurotransmitter
    Language English
    Publishing date 2004-10
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-004-0173-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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