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  1. Article ; Online: Association between level of care and colonization with resistant gram-negative bacteria among nursing-home residents - CORRIGENDUM.

    Adediran, Timileyin Y / Sethuraman, Kinjal N / Leekha, Surbhi / Roghmann, Mary-Claire

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 7, Page(s) 1207

    MeSH term(s) Humans ; Gram-Negative Bacteria ; Nursing Homes ; Risk Factors ; Gram-Negative Bacterial Infections
    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2022.177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Association between level of care and colonization with resistant gram-negative bacteria among nursing-home residents.

    Adediran, Timileyin Y / Sethuraman, Kinjal N / Leekha, Surbhi / Roghmann, Mary-Claire

    Infection control and hospital epidemiology

    2021  Volume 42, Issue 6, Page(s) 760–762

    Abstract: In this cross-sectional study, we examined the relationship between resident level of care in the nursing home and colonization with resistant gram-negative bacteria. Residential-care residents were more likely to be colonized with resistant gram- ... ...

    Abstract In this cross-sectional study, we examined the relationship between resident level of care in the nursing home and colonization with resistant gram-negative bacteria. Residential-care residents were more likely to be colonized with resistant gram-negative bacteria than were postacute care residents (odds ratio, 2.3; 95% confidence interval, 1.40-3.80; P < .001).
    MeSH term(s) Cross-Sectional Studies ; Gram-Negative Bacteria ; Gram-Negative Bacterial Infections/epidemiology ; Humans ; Nursing Homes ; Risk Factors
    Language English
    Publishing date 2021-03-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.1274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Factors associated with patient-to-healthcare personnel (HCP) and HCP-to-subsequent patient transmission of methicillin-resistant

    Adediran, Timileyin Y / Robinson, Gwen L / Johnson, J Kristie / Liang, Yuanyuan / Bejo, Sarah / Leekha, Surbhi / Rasko, David A / Stine, O Colin / Harris, Anthony D / Thom, Kerri A

    Infection control and hospital epidemiology

    2024  Volume 45, Issue 5, Page(s) 583–589

    Abstract: Background: Transient acquisition of methicillin-resistant : Methods: We conducted a prospective cohort study with 2 parts. In objective 1, we studied MRSA transmission from random MRSA-positive patients to HCP gloves and gowns after specific routine ...

    Abstract Background: Transient acquisition of methicillin-resistant
    Methods: We conducted a prospective cohort study with 2 parts. In objective 1, we studied MRSA transmission from random MRSA-positive patients to HCP gloves and gowns after specific routine patient care activities. In objective 2, we simulated subsequent transmission from random HCP gloves and gowns without hand hygiene to the next patient using a manikin proxy.
    Results: For the first objective, among 98 MRSA-positive patients with 333 randomly selected individual patient-HCP interactions, HCP gloves or gowns were contaminated in 54 interactions (16.2%). In a multivariable analysis, performing endotracheal tube care had the greatest odds of glove or gown contamination (OR, 4.06; 95% CI, 1.3-12.6 relative to physical examination). For the second objective, after 147 simulated HCP-patient interactions, the subsequent transmission of MRSA to the manikin proxy occurred 15 times (10.2%).
    Conclusion: After caring for a patient with MRSA, contamination of HCP gloves and gown and transmission to subsequent patients following HCP-patient interactions occurs frequently if contact precautions are not used. Proper infection control practices, including the use of gloves and gown, can prevent this potential subsequent transmission.
    MeSH term(s) Humans ; Methicillin-Resistant Staphylococcus aureus ; Cross Infection/prevention & control ; Gloves, Protective ; Prospective Studies ; Health Personnel ; Infection Control ; Staphylococcal Infections/prevention & control
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2023.269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Molecular concordance of methicillin-resistant

    Adediran, Timileyin Y / Hitchcock, Stephanie / Johnson, J Kristie / Stine, O Colin / Leekha, Surbhi / Thom, Kerri A / Liang, Yuanyuan / Rasko, David A / Harris, Anthony D

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 4, Page(s) 578–588

    Abstract: Background: Methicillin-resistant : Methods: From a multisite cohort of 388 independent patient MRSA isolates and their corresponding HCP gown and glove isolates, we selected 91 isolates pairs using a probability to proportion size (PPS) sampling ... ...

    Abstract Background: Methicillin-resistant
    Methods: From a multisite cohort of 388 independent patient MRSA isolates and their corresponding HCP gown and glove isolates, we selected 91 isolates pairs using a probability to proportion size (PPS) sampling method. To determine whether the patient and HCP gown or gloves isolates were genetically similar, we used 5 comparative genomic typing methods: phylogenetic analysis,
    Results: We identified that 56 (61.5%) of isolate pairs were genetically similar at least by 4 of the methods. Comparably, the
    Conclusions: Many of the patient MRSA isolates were genetically similar to those on the HCP gown or gloves following a patient care activity. This finding indicates that the patient is often the primary source of the MRSA isolates transmitted to the HCP, which can potentially be spread to other patients or hospital settings through HCP vectors. These results have important implications because they provide additional evidence for hospitals considering ending the use of contact precautions (gloves and gowns) for MRSA patients.
    MeSH term(s) Humans ; Methicillin-Resistant Staphylococcus aureus ; Staphylococcal Infections ; Multilocus Sequence Typing ; Phylogeny ; Health Personnel
    Language English
    Publishing date 2022-09-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2022.159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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