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  1. Article: Commentary on "Navigation-Guided/Robot-Assisted Spinal Surgery: A Review Article".

    Adler, John R

    Neurospine

    2024  Volume 21, Issue 1, Page(s) 18–19

    Language English
    Publishing date 2024-03-31
    Publishing country Korea (South)
    Document type Journal Article ; Comment
    ZDB-ID 3031654-6
    ISSN 2586-6591 ; 2586-6583
    ISSN (online) 2586-6591
    ISSN 2586-6583
    DOI 10.14245/ns.2448256.128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Conference proceedings: Cyberknife stereotactic robotic radiosurgery

    Adler, John R.

    [7th Annual CyberKnife Users' Meeting, January 23-27, 2008 in Scottsdale, Ariz.]

    (Neurosurgery ; 64,2, Suppl.)

    2009  

    Event/congress CyberKnife User's Meeting (7, 2008, ScottsdaleAriz.)
    Author's details John R. Adler ..., guest ed
    Series title Neurosurgery ; 64,2, Suppl.
    Collection
    Language English
    Size N3, A122 S. : Ill., graph. Darst.
    Publisher Lippincott Williams & Wilkins
    Publishing place Hagerstown, Md
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT015880866
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Remote Robotic Spine Surgery.

    Adler, John R

    Neurospine

    2020  Volume 17, Issue 1, Page(s) 121–122

    Language English
    Publishing date 2020-03-31
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 3031654-6
    ISSN 2586-6591 ; 2586-6583
    ISSN (online) 2586-6591
    ISSN 2586-6583
    DOI 10.14245/ns.2040088.044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: In Reply: The Zap-X Radiosurgical System in the Treatment of Intracranial Tumors: A Technical Case Report.

    Adler, John R / Weidlich, Georg

    Neurosurgery

    2021  Volume 88, Issue 6, Page(s) E579

    MeSH term(s) Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/surgery ; Humans ; Radiosurgery
    Language English
    Publishing date 2021-03-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyab081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: New technologies in radiation oncology

    Adler, John R. / Schlegel, Wolfgang

    with 39 tables

    (Medical radiology : Radiation oncology)

    2006  

    Author's details W. Schlegel ... (ed.). With contributions by J. R. Adler
    Series title Medical radiology : Radiation oncology
    Keywords Strahlentherapie ; Dreidimensionale Bildverarbeitung ; Bestrahlungsplan
    Subject Bestrahlungsplanung ; Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie
    Language English
    Size XIII, 460 S. : zahlr. Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT014524304
    ISBN 3-540-00321-5 ; 978-3-540-00321-2
    Database Catalogue ZB MED Medicine, Health

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  6. Article: Neuromodulation via Focal Radiation: Radiomodulation Update.

    Schneider, M Bret / Walcott, Brian / Adler, John R

    Cureus

    2021  Volume 13, Issue 4, Page(s) e14700

    Abstract: When radiation is focally delivered to brain tissue at sub-ablative doses, neural activity may be altered. When done at a specific brain circuit node or connection, this is referred to as "radiomodulation." Radiation-induced effects on brain tissue, ... ...

    Abstract When radiation is focally delivered to brain tissue at sub-ablative doses, neural activity may be altered. When done at a specific brain circuit node or connection, this is referred to as "radiomodulation." Radiation-induced effects on brain tissue, basic science, and clinical research that supports the radiomodulation hypothesis are reviewed in this article. We review progress in defining the necessary parameters in terms of dose, volumes, and anatomical location. It may be possible to deliver therapeutic neuromodulation that is non-invasive, non-destructive, and durable.
    Language English
    Publishing date 2021-04-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Lichenoid Keratosis Skin Biopsy: A Case Report of Malignant Hospital Charges.

    Adler, John R / Do, Hong / Pfeffer, Jeffrey

    Cureus

    2021  Volume 13, Issue 2, Page(s) e13292

    Abstract: Skin cancers are the most common malignancy and are especially common among light-skinned individuals in sun-exposed areas. While in many cases, a characteristic or classic appearance of the lesion is sufficient to make a definitive diagnosis, shave ... ...

    Abstract Skin cancers are the most common malignancy and are especially common among light-skinned individuals in sun-exposed areas. While in many cases, a characteristic or classic appearance of the lesion is sufficient to make a definitive diagnosis, shave biopsy remains an important procedure when diagnosing many such raised lesions. Over the span of two months, a 66-year-old Caucasian male noted the appearance of a small, raised pruritic scaly lesion over his right upper chest. The differential diagnosis included both cancerous and benign lesions. During a 15-minute clinic visit, a simple shave biopsy was performed, and additionally, 10 small actinic keratoses on the patient's arms, legs, and back were treated with cryotherapy using liquid nitrogen. Later, a histologic examination of the biopsied lesion revealed a benign lichenoid keratosis. The patient was billed $10,187 for this outpatient experience.
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.13292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Socio-economic disparities influence likelihood of post-operative radiation to resection cavities of metastatic brain tumors.

    Haider, Ghani / Dadey, David Y A / Rodrigues, Adrian / Pollom, Erqi L / Adler, John R / Veeravagu, Anand

    Acta neurochirurgica

    2023  Volume 165, Issue 12, Page(s) 4253–4258

    Abstract: Purpose: Irradiating the surgical bed of resected brain metastases improves local and distant disease control. Over time, stereotactic radiosurgery (SRS) has replaced whole brain radiotherapy (WBRT) as the treatment standard of care because it minimizes ...

    Abstract Purpose: Irradiating the surgical bed of resected brain metastases improves local and distant disease control. Over time, stereotactic radiosurgery (SRS) has replaced whole brain radiotherapy (WBRT) as the treatment standard of care because it minimizes long-term damage to neuro-cognition. Despite this data and growing adoption, socio-economic disparities in clinical access can result in sub-standard care for some patient populations. We aimed to analyze the clinical and socio-economic characteristics of patients who did not receive radiation after surgical resection of brain metastasis.
    Methods: Our sample was obtained from Clinformatics® Data Mart Database and included all patients from 2004 to 2021 who did or did not receive radiation treatment within sixty days after resection of tumors metastatic to the brain. Regression analysis was done to identify factors responsible for loss to adjuvant radiation treatment.
    Results: Of 8362 patients identified who had undergone craniotomy for resection of metastatic brain tumors, 3430 (41%) patients did not receive any radiation treatment. Compared to patients who did receive some form of radiation treatment (SRS or WBRT), patients who did not get any form of radiation were more likely to be older (p = 0.0189) and non-white (p = 0.008). Patients with Elixhauser Comorbidity Index ≥3 were less likely to receive radiation treatment (p < 0.01). Fewer patients with household income ≥ $75,000 did not receive radiation treatment (p < 0.01).
    Conclusion: Age, race, household income, and comorbidity status were associated with differential likelihood to receive post-operative radiation treatment.
    MeSH term(s) Humans ; Brain Neoplasms/radiotherapy ; Brain Neoplasms/surgery ; Brain Neoplasms/secondary ; Brain ; Radiosurgery/adverse effects ; Radiotherapy, Adjuvant ; Socioeconomic Factors ; Cranial Irradiation ; Treatment Outcome
    Language English
    Publishing date 2023-10-10
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05826-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The future of robotics in radiosurgery.

    Adler, John R

    Neurosurgery

    2013  Volume 72 Suppl 1, Page(s) 8–11

    Abstract: After emerging from and transforming the practice of neurosurgery, stereotactic radiosurgery is increasingly affecting all surgical disciplines. The first generation of frame-based devices limited radiosurgery treatment to lesions of the brain where the ... ...

    Abstract After emerging from and transforming the practice of neurosurgery, stereotactic radiosurgery is increasingly affecting all surgical disciplines. The first generation of frame-based devices limited radiosurgery treatment to lesions of the brain where the rigidity of the skull provided adequate skeletal purchase. In an effort to surmount such anatomic limitations, robotic radiosurgery was developed. After almost 2 decades of existence, the technology and clinical application of image-guided robotic radiosurgery have evolved considerably, and today a range of treatments with such technology have become commonplace. Nevertheless, the timeless allure of a truly noninvasive, yet highly effective, therapy promises that further refinements in robotic radiosurgery will be forthcoming well into the future.
    MeSH term(s) Humans ; Neurosurgical Procedures/instrumentation ; Neurosurgical Procedures/trends ; Radiosurgery/instrumentation ; Radiosurgery/trends ; Robotics/instrumentation ; Robotics/trends ; Surgery, Computer-Assisted/instrumentation ; Surgery, Computer-Assisted/trends
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/NEU.0b013e318271ff20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of socio-economic factors on radiation treatment after resection of metastatic brain tumors: trends from a private insurance database.

    Dadey, David Y A / Rodrigues, Adrian / Haider, Ghani / Pollom, Erqi L / Adler, John R / Veeravagu, Anand

    Journal of neuro-oncology

    2022  Volume 158, Issue 3, Page(s) 445–451

    Abstract: Background: Stereotactic radiosurgery (SRS) to the surgical bed of resected brain metastases is now considered the standard of care due to its advantages over whole brain radiation therapy (WBRT). Despite the upward trend in SRS adoption since the 2000s, ...

    Abstract Background: Stereotactic radiosurgery (SRS) to the surgical bed of resected brain metastases is now considered the standard of care due to its advantages over whole brain radiation therapy (WBRT). Despite the upward trend in SRS adoption since the 2000s, disparities have been reported suggesting that socio-economic factors can influence SRS utilization.
    Objective: To analyze recent trends in SRS use and identify factors that influence treatment.
    Methods: We conducted a retrospective cohort study with the Optum Commercial Claims and Encounters Database and included all patients from 2004 to 2021 who received SRS or WBRT within 60 days after resection of tumors metastatic to the brain.
    Results: A total of 3495 patients met the inclusion and exclusion criteria. There were 1998 patients in the SRS group and 1497 patients in the WBRT group. SRS use now supersedes WBRT by a wide margin. Lung, breast and colon were the most common sites of primary tumor. Although we found no significant differences based on race among the treatment groups, patients with annual household income greater than $75,000 and those with some college or higher education are significantly more likely to receive SRS (OR 1.44 and 1.30; 95% CI 1.18-1.76 and 1.08-1.56; P = 0.001 and 0.005, respective). Patients with Elixhauser Comorbidity Index of three or more were significantly more likely to receive SRS treatment.
    Conclusion: The use of post-surgical SRS for brain metastasis has increased significantly over time, however education and income were associated with differential SRS utilization.
    MeSH term(s) Brain Neoplasms/radiotherapy ; Brain Neoplasms/secondary ; Brain Neoplasms/surgery ; Cranial Irradiation ; Economic Factors ; Humans ; Insurance ; Radiosurgery ; Retrospective Studies
    Language English
    Publishing date 2022-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604875-4
    ISSN 1573-7373 ; 0167-594X
    ISSN (online) 1573-7373
    ISSN 0167-594X
    DOI 10.1007/s11060-022-04031-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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