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  1. Book: Atlas of complex orthodontics

    Nanda, Ravindra / Uribe, Flavio Andres / Agarwal, Sachin

    2017  

    Title variant Complex orthodontics
    Author's details Ravindra Nanda, BDS, MDS, PhD; Flavio Andres Uribe, DDS, MDentSc ; with significant contribution by Sachin Agarwal, BDS, MDS, MDentSc (University of Connecticut, USA), Cert Orth (University of Connecticut, USA)
    Keywords Kieferorthopädie
    Subject Orthodontie
    Language English
    Size x, 409 Seiten, Illustrationen, Diagramme
    Publisher Elsevier
    Publishing place St. Louis, Missouri
    Publishing country United States
    Document type Book
    Note Includes index
    HBZ-ID HT019389247
    ISBN 978-0-323-08710-0 ; 0-323-08710-8 ; 9780323357548 ; 0323357547
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Physician Family Conflict Following Cardiac Arrest: A Qualitative Study.

    Caplan, Rachel / Agarwal, Sachin / Dastidar, Joyeeta G

    Narrative inquiry in bioethics

    2024  Volume 13, Issue 2, Page(s) 129–137

    Abstract: Comatose survivors of cardiac arrest may die following withdrawal of life-sustaining therapy (WLST) due to poor neurologic prognosis. Family members, acting as surrogate decision makers, are frequently asked to decide whether the patient should continue ... ...

    Abstract Comatose survivors of cardiac arrest may die following withdrawal of life-sustaining therapy (WLST) due to poor neurologic prognosis. Family members, acting as surrogate decision makers, are frequently asked to decide whether the patient should continue to receive ongoing life-sustaining therapy such as mechanical ventilation in this context of risk of death following removal. Sometimes, physicians and family members disagree about what is in the patient's best interest, and this conflict causes distress for both families and medical personnel.This article examines themes recorded in the medical records of 24 cardiac arrest patients at Columbia University Medical Center (CUMC) whose families chose to pursue continued life support despite physician recommendations for withdrawal. In documented conversations between patients' families and their providers, the most prominent themes included faith in miracles, the inappropriateness of "playing God," the value of more time with the patient, and differences in how providers and family members perceived the patient's status.
    MeSH term(s) Humans ; Heart Arrest/therapy ; Family ; Female ; Male ; Qualitative Research ; Withholding Treatment/ethics ; Physicians ; Professional-Family Relations ; Middle Aged ; Decision Making ; Adult ; Aged ; Life Support Care/ethics ; Family Conflict
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2632728-4
    ISSN 2157-1740 ; 2157-1732
    ISSN (online) 2157-1740
    ISSN 2157-1732
    DOI 10.1353/nib.2023.a909673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of the effects of ivermectin, permethrin, and gamma benzene hexachloride alone and with that of combination therapy for the management of scabies.

    Dey, Saborni / Agarwal, Sachin / Sagar

    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique

    2022  Volume 29, Issue 1, Page(s) e87–e96

    Abstract: Results: The present study compared three scabicidal agents alone or with combination, the currently considered medicine of choice permethrin, oral ivermectin, and gamma benzene hexachloride in the local population of India. A total of 120 patients were ...

    Abstract Results: The present study compared three scabicidal agents alone or with combination, the currently considered medicine of choice permethrin, oral ivermectin, and gamma benzene hexachloride in the local population of India. A total of 120 patients were studied. They were randomly divided into four groups -Group A, Group B, Group C, and Group D. Group A received topical 5% permethrin and oral placebo. Group B was given topical placebo cream and oral ivermectin in two dose regimen. Group C received topical 1% gamma benzene hexachloride with oral placebo, and Group D was given topical 5% permethrin and oral ivermectin. The improvement of lesions and pruritus were assessed in the next three follow-ups, i.e., on the 7th day, 14th day, and 28th day along with any adverse drug reactions (ADRs). It was found that Group A had 83%, 90%, 97%, and Group B had 70%, 81%, and 91% improvement of lesions in the three follow-ups respectively. Group C showed 57%, 70%, 86%, and Group D had 82%, 90%, 97% efficiency to decrease lesion count (p>0.05) respectively. Again, Group A observed 77%, 88%, and 94% improvement in pruritus in subsequent follow-ups, while for Group B it was 63%, 76%, and 86%. Group C had 55%, 71%, 85% efficiency, and Group D had recorded 77%, 88%, and 94% improvement to decrease pruritus (p>0.05). The incidence of adverse effects was found to be less in Group B, Group C, and Group D when compared to Group A.
    Conclusion: Group D or a combination therapy was a better choice for scabies in comparison to other monotherapy due to its better efficacy and safety profile.
    MeSH term(s) Administration, Oral ; Drug-Related Side Effects and Adverse Reactions ; Hexachlorocyclohexane/adverse effects ; Humans ; Insecticides/adverse effects ; Ivermectin/adverse effects ; Permethrin/adverse effects ; Pruritus ; Scabies/drug therapy ; Scabies/pathology
    Chemical Substances Insecticides ; Permethrin (509F88P9SZ) ; Hexachlorocyclohexane (59NEE7PCAB) ; Ivermectin (70288-86-7)
    Language English
    Publishing date 2022-03-15
    Publishing country Australia
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 2561-8741
    ISSN (online) 2561-8741
    DOI 10.47750/jptcp.2022.845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Decoding code status after cardiac arrest.

    Hernandez, Samantha Fernandez / Agarwal, Sachin

    Resuscitation

    2022  Volume 181, Page(s) 37–39

    MeSH term(s) Humans ; Heart Arrest/therapy ; Cardiopulmonary Resuscitation
    Language English
    Publishing date 2022-10-19
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2022.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A shift towards targeted post-ICU treatment: Multidisciplinary care for cardiac arrest survivors.

    Sayde, George E / Shapiro, Peter A / Kronish, Ian / Agarwal, Sachin

    Journal of critical care

    2024  Volume 82, Page(s) 154798

    Abstract: Intensive Care Unit (ICU) survivorship comprises a burgeoning area of critical care medicine, largely due to our improved understanding of and concern for patients' recovery trajectory, and efforts to mitigate the post-acute complications of critical ... ...

    Abstract Intensive Care Unit (ICU) survivorship comprises a burgeoning area of critical care medicine, largely due to our improved understanding of and concern for patients' recovery trajectory, and efforts to mitigate the post-acute complications of critical illness. Expansion of care beyond hospitalization is necessary, yet evidence for post-ICU clinics remains limited and mixed, as both interventions and target populations studied to date are too heterogenous to meaningfully demonstrate efficacy. Here, we briefly present the existing evidence and limitations related to post-ICU clinics, identify cardiac arrest survivors as a unique ICU subpopulation warranting further investigation and treatment, and propose a clinical framework that addresses the multifaceted needs of this well-defined patient population.
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2024.154798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cognitive Assessments in Critical Care Patient Populations: Methodological Considerations.

    Agarwal, Sachin / Pavol, Marykay

    Neurocritical care

    2021  Volume 34, Issue 2, Page(s) 379–381

    MeSH term(s) Cognition ; Critical Care ; Data Collection ; Humans
    Language English
    Publishing date 2021-01-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-020-01187-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Feasibility of a remote heart rate variability biofeedback intervention for reducing anxiety in cardiac arrest survivors: A pilot trial.

    Birk, Jeffrey L / Cumella, Robin / Lopez-Veneros, David / Agarwal, Sachin / Kronish, Ian M

    Contemporary clinical trials communications

    2024  Volume 37, Page(s) 101251

    Abstract: Background: Heart rate variability biofeedback (HRVB) is a promising non-pharmacologic approach for reducing anxiety. This intervention's feasibility needs testing in psychologically distressed cardiac patients for whom heart-related anxiety is a core ... ...

    Abstract Background: Heart rate variability biofeedback (HRVB) is a promising non-pharmacologic approach for reducing anxiety. This intervention's feasibility needs testing in psychologically distressed cardiac patients for whom heart-related anxiety is a core concern. To enhance scalability and convenience, remote delivery of HRVB also needs to be assessed. Accordingly, we evaluated the feasibility of remote HRVB in survivors of cardiac arrest (CA) with elevated CA-related psychological distress.
    Methods: The intervention was comprised of daily sessions of diaphragmatic paced breathing and real-time monitoring of cardiac activity guided by a smartphone app and heart rate monitor. This single-arm feasibility trial assessed the percentage of eligible contacted patients who consented and engaged in the study and the self-reported acceptability, feasibility, appropriateness, and usability of the intervention. Exploratory analyses assessed pre-to-post changes in trait anxiety, negative affect, cardiac-related interoceptive fear, and resting-state HRV.
    Results: Of 12 eligible CA survivors contacted, 10 enrolled. All 10 patients completed the virtual study visits and the majority (>50 %) of prescribed training sessions. Ninety percent reported good scores for intervention acceptability and feasibility, and 80 % reported good scores for its appropriateness and usability for reducing fear. Trait anxiety decreased significantly pre-to-post intervention. There were no changes in negative affect, interoceptive fear, or resting state HRV.
    Conclusion: A remotely delivered HRVB intervention was acceptable, feasible, and useable for cardiac patients with CA-related psychological distress. A phase 2 randomized controlled trial evaluating the efficacy of HRVB on cardiac patients' psychological distress, health behaviors, and autonomic dysfunction may be warranted.
    Language English
    Publishing date 2024-01-08
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2451-8654
    ISSN (online) 2451-8654
    DOI 10.1016/j.conctc.2023.101251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cardiac Arrest and Neurologic Recovery: Insights from the Case of Mr. Damar Hamlin.

    Geocadin, Romergryko G / Agarwal, Sachin / Goss, Adeline L / Callaway, Clifton W / Richie, Megan

    Annals of neurology

    2023  Volume 93, Issue 5, Page(s) 871–876

    Abstract: The association between brain injury after cardiac arrest and poor survival outcomes has led to longstanding pessimism. However, the publicly witnessed cardiac arrest, resuscitation, and acute management of Mr. Damar Hamlin and his favorable neurologic ... ...

    Abstract The association between brain injury after cardiac arrest and poor survival outcomes has led to longstanding pessimism. However, the publicly witnessed cardiac arrest, resuscitation, and acute management of Mr. Damar Hamlin and his favorable neurologic recovery provides some optimism. Mr. Hamlin's case highlights the neurologic advances of the last 2 decades and presents the opportunity to improve outcomes for all cardiac arrest patients in key areas: (1) effectively implementing the American Heart Association "Chain of Survival" to prevent initial brain injury and promote neuroprotection; (2) revisiting the process of neurologic prognostication and re-defining the brain recovery during the early periods, and (3) incorporating neurorehabilitation into existing cardiac rehabilitation models to support holistic recovery. ANN NEUROL 2023;93:871-876.
    MeSH term(s) Humans ; Cardiopulmonary Resuscitation ; Heart Arrest/complications ; Brain Injuries ; Brain ; Registries
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Heart rate and heart rate variability as a prognosticating feature for functional outcome after cardiac arrest: A scoping review.

    Kwon, Soon Bin / Megjhani, Murad / Nametz, Daniel / Agarwal, Sachin / Park, Soojin

    Resuscitation plus

    2023  Volume 15, Page(s) 100450

    Abstract: Background: Despite significant progress in cardiopulmonary resuscitation and post-cardiac arrest care, favorable outcome in out-of hospital sudden cardiac arrest patients remains low. One of the main reasons for mortality in these patients is ... ...

    Abstract Background: Despite significant progress in cardiopulmonary resuscitation and post-cardiac arrest care, favorable outcome in out-of hospital sudden cardiac arrest patients remains low. One of the main reasons for mortality in these patients is withdrawal of life-sustaining treatment. There is a need for precise and equitable prognostication tools to support families in avoiding premature or inappropriate WLST. Heart rate (HR) and heart rate variability (HRV) have been noted for their association with outcome, and are positioned to be a useful modality for prognostication.
    Objectives: The aim of this scoping review is to rigorously explore which electrocardiography features have been shown to predict functional outcome in post-cardiac arrest patients.
    Methods: The search was performed in Pubmed, EMBASE, and SCOPUS for studies published from January 1, 2011, to September 29, 2022, including papers in English or Korean.
    Results: Seven studies were included with a total of 1359 patients. Four studies evaluated HR, one study evaluated RR inverval, and two studies evaluated HRV. All studies were retrospective, with 3 multi-center and 4 single-center studies. All seven studies were inclusive of patients who underwent targeted temperature management (TTM) after cardiac arrest, and two studies included patients without TTM. Five studies used cerebral performance category to assess functional outcome, two studies used Glasgow outcome score, and one study used modified Rankin scale. Three studies measured outcome at hospital discharge, one study measured outcome at 14 days after return of spontaneous circulation, two studies measured outcome after 3 months, and one after 1 year. In all studies that evaluated HR, lower HR was associated with favorable functional outcome. Two studies found that higher complexity of HRV was associated with favorable functional outcome.
    Conclusion: HR and HRV showed clear associations with functional outcome in patients after CA, but cinilcial utility for prognostication is uncertain.
    Language English
    Publishing date 2023-08-17
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2666-5204
    ISSN (online) 2666-5204
    DOI 10.1016/j.resplu.2023.100450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: High-quality CPR training: Let's get smart!

    Agarwal, Sachin / Abella, Benjamin S

    Resuscitation

    2019  Volume 144, Page(s) 185–186

    MeSH term(s) Cardiopulmonary Resuscitation
    Language English
    Publishing date 2019-09-17
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2019.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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