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Article ; Online: Transapical combined transcatheter aortic valve-in-valve implant and ascending aorta endovascular repair.

Agostinelli, Andrea / Gallingani, Alan / Borrello, Bruno / Nicolini, Francesco

Interactive cardiovascular and thoracic surgery

2022 Volume 34, Issue 6, Page(s) 1183–1185

Abstract: We report the case of a 64-year-old patient who previously had an aortic valve replacement with a stentless aortic valve and an ascending aorta replacement for a DeBakey type II aortic dissection. The patient was referred to us for symptomatic aortic ... ...

Abstract	We report the case of a 64-year-old patient who previously had an aortic valve replacement with a stentless aortic valve and an ascending aorta replacement for a DeBakey type II aortic dissection. The patient was referred to us for symptomatic aortic regurgitation related to bioprosthesis degeneration and a pseudoaneurysm at the distal anastomotic site of the vascular graft. Due to the presence of several comorbidities, the patient had a combined transapical transcatheter aortic valve-in-valve implant and an ascending aorta endovascular repair.
MeSH term(s)	Aorta/surgery ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Endovascular Procedures/adverse effects ; Heart Valve Prosthesis ; Humans ; Middle Aged ; Prosthesis Design ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome
Language	English
Publishing date	2022-01-24
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivac002
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Article ; Online: Improving Auditory Perception in Pediatric Single-Sided Deafness: Use of Cochlear Implants' Direct Connection for Remote Speech Perception Rehabilitation.

Agostinelli, Anna / Pegolo, Margherita / Montino, Silvia / Maritan, Francesca / Gambalonga, Mattia / Trevisi, Patrizia / Brotto, Davide

American journal of audiology

2022 Volume 32, Issue 1, Page(s) 52–58

Abstract: Purpose: Unilateral cochlear implants (CIs) can restore binaural hearing in single-sided deafness (SSD). Direct stimulation of the CI can be obtained via the Bluetooth connection of a device to the CI, thus excluding the typical-hearing ear. This study ... ...

Abstract	Purpose: Unilateral cochlear implants (CIs) can restore binaural hearing in single-sided deafness (SSD). Direct stimulation of the CI can be obtained via the Bluetooth connection of a device to the CI, thus excluding the typical-hearing ear. This study aims to investigate the use of CI connectivity features as a rehabilitative strategy in a small cohort of children affected by SSD. Method: A newly developed training protocol was presented to children with SSD who have less than 2 years of experience with CI. We developed a user-friendly and short-term (six sessions within 20 days) training protocol for speech perception that patients themselves can manage independently at home using CI connectivity systems. Children were telematically tested before and after the training by trained speech and language therapists. Results: Four patients met the inclusion criteria. They all showed better results in the final online assessment, when compared with the initial one. Conclusions: To our knowledge, this is the first clinical focus article presenting an auditory training protocol for SSD patients with CI using the Bluetooth connectivity systems for teletherapy. The results, although preliminary, support the efficacy of this rehabilitative strategy. Further research is needed to support our findings.
MeSH term(s)	Humans ; Child ; Cochlear Implants ; Speech Perception/physiology ; Deafness/rehabilitation ; Hearing Loss, Unilateral/rehabilitation ; Noise ; Cochlear Implantation/methods
Language	English
Publishing date	2022-12-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	1162315-9
ISSN	1558-9137 ; 1059-0889
ISSN (online)	1558-9137
ISSN	1059-0889
DOI	10.1044/2022_AJA-21-00271
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Article ; Online: Magnetic Resonance Imaging (MRI) Analysis of Tissue Sodium Concentration in Chronic Kidney Disease.

Martin, Kylie / Venkatraman, Vijay / Agostinelli, Angela / Thai, Braden / Stäb, Daniel / Hewitson, Tim D / Tan, Sven-Jean / Toussaint, Nigel D / Robertson, Patsy

Methods in molecular biology (Clifton, N.J.)

2023 Volume 2664, Page(s) 161–171

Abstract: Human body sodium is regulated by the kidneys and extrarenal mechanisms. Stored skin and muscle tissue sodium accumulation is associated with kidney function decline, hypertension, and a pro-inflammatory and cardiovascular disease profile. In this ... ...

Abstract	Human body sodium is regulated by the kidneys and extrarenal mechanisms. Stored skin and muscle tissue sodium accumulation is associated with kidney function decline, hypertension, and a pro-inflammatory and cardiovascular disease profile. In this chapter, we describe the use of sodium-hydrogen magnetic resonance imaging (
MeSH term(s)	Humans ; Sodium/metabolism ; Muscle, Skeletal/metabolism ; Magnetic Resonance Imaging/methods ; Hypertension/metabolism ; Kidney/metabolism ; Renal Insufficiency, Chronic/diagnostic imaging ; Renal Insufficiency, Chronic/metabolism ; Water/metabolism
Chemical Substances	Sodium (9NEZ333N27) ; Water (059QF0KO0R)
Language	English
Publishing date	2023-07-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-3179-9_12
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Article ; Online: Benefits of bone conduction hearing aid in children with unilateral aural atresia.

Brotto, Davide / Sorrentino, Flavia / Cazzador, Diego / Maritan, Francesca / Montino, Silvia / Agostinelli, Anna / Zanoletti, Elisabetta / Martini, Alessandro / Bovo, Roberto / Trevisi, Patrizia

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

2023 Volume 43, Issue 3, Page(s) 221–226

Abstract: Objective: To assess the hearing benefit with a unilateral bone conduction hearing aid in a cohort of children with unilateral aural atresia.: Methods: Cross-sectional case series pilot study involving 7 children (median age: 10 years, range 6-11). ... ...

Abstract	Objective: To assess the hearing benefit with a unilateral bone conduction hearing aid in a cohort of children with unilateral aural atresia. Methods: Cross-sectional case series pilot study involving 7 children (median age: 10 years, range 6-11). All patients underwent pure-tone, speech, aided sound field and aided speech audiometry and Simplified Italian Matrix Test (SIMT) with and without bone conduction hearing aid (Baha 5 Results: The mean air conduction pure-tone average (PTA) of the atretic ear was 63.2 ± 6.9 dB, while the bone conduction PTA was 12.6 ± 4.7 dB. Speech discrimination score of the atretic ear was 88.6 ± 3.8 dB, while with the hearing aid it was 52.8 ± 1.9 dB. In the contralateral ear, there was no significant air-bone gap, and PTAs for air and bone conduction thresholds were within normal range (PTA ≤ 25 dB). The mean aided air conduction hearing threshold was 26.2 ± 7.97. Mean speech recognition threshold without the hearing aid was -5.1 ± 1.9 dB, and -6.0 ± 1.7 dB with the hearing aid tested with the SIMT. The mean score of the cognitive test was 46.8 ± 42.8. Conclusions: These preliminary findings should encourage clinicians in proposing a unilateral bone conduction hearing aid in children with unilateral atresia.
MeSH term(s)	Humans ; Child ; Hearing Aids ; Bone Conduction ; Cross-Sectional Studies ; Pilot Projects ; Ear/abnormalities ; Hearing Loss, Conductive ; Speech Perception ; Treatment Outcome
Language	English
Publishing date	2023-06-02
Publishing country	Italy
Document type	Journal Article
ZDB-ID	604898-5
ISSN	1827-675X ; 0392-100X
ISSN (online)	1827-675X
ISSN	0392-100X
DOI	10.14639/0392-100X-N2271
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Book ; Online: Transferability Metrics for Selecting Source Model Ensembles

Agostinelli, Andrea / Uijlings, Jasper / Mensink, Thomas / Ferrari, Vittorio

2021

Abstract: We address the problem of ensemble selection in transfer learning: Given a large pool of source models we want to select an ensemble of models which, after fine-tuning on the target training set, yields the best performance on the target test set. Since ... ...

Abstract	We address the problem of ensemble selection in transfer learning: Given a large pool of source models we want to select an ensemble of models which, after fine-tuning on the target training set, yields the best performance on the target test set. Since fine-tuning all possible ensembles is computationally prohibitive, we aim at predicting performance on the target dataset using a computationally efficient transferability metric. We propose several new transferability metrics designed for this task and evaluate them in a challenging and realistic transfer learning setup for semantic segmentation: we create a large and diverse pool of source models by considering 17 source datasets covering a wide variety of image domain, two different architectures, and two pre-training schemes. Given this pool, we then automatically select a subset to form an ensemble performing well on a given target dataset. We compare the ensemble selected by our method to two baselines which select a single source model, either (1) from the same pool as our method; or (2) from a pool containing large source models, each with similar capacity as an ensemble. Averaged over 17 target datasets, we outperform these baselines by 6.0% and 2.5% relative mean IoU, respectively.
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2021-11-25
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: How stable are Transferability Metrics evaluations?

Agostinelli, Andrea / Pándy, Michal / Uijlings, Jasper / Mensink, Thomas / Ferrari, Vittorio

2022

Abstract: Transferability metrics is a maturing field with increasing interest, which aims at providing heuristics for selecting the most suitable source models to transfer to a given target dataset, without fine-tuning them all. However, existing works rely on ... ...

Abstract	Transferability metrics is a maturing field with increasing interest, which aims at providing heuristics for selecting the most suitable source models to transfer to a given target dataset, without fine-tuning them all. However, existing works rely on custom experimental setups which differ across papers, leading to inconsistent conclusions about which transferability metrics work best. In this paper we conduct a large-scale study by systematically constructing a broad range of 715k experimental setup variations. We discover that even small variations to an experimental setup lead to different conclusions about the superiority of a transferability metric over another. Then we propose better evaluations by aggregating across many experiments, enabling to reach more stable conclusions. As a result, we reveal the superiority of LogME at selecting good source datasets to transfer from in a semantic segmentation scenario, NLEEP at selecting good source architectures in an image classification scenario, and GBC at determining which target task benefits most from a given source model. Yet, no single transferability metric works best in all scenarios.
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2022-04-04
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Radiological Evaluation of the Dimensions of Lower Molar Alveoli.

Agostinelli, Claudio / Agostinelli, Agnese / Berardini, Marco / Trisi, Paolo

Implant dentistry

2018 Volume 27, Issue 3, Page(s) 271–275

Abstract: Purpose: The aim of the present radiological study was to analyze the alveolar bone morphology of the lower molars in physiological conditions. The main goal is to describe the bone anatomy of a hypothetically postextractive site in lower molar area.: ...

Abstract	Purpose: The aim of the present radiological study was to analyze the alveolar bone morphology of the lower molars in physiological conditions. The main goal is to describe the bone anatomy of a hypothetically postextractive site in lower molar area. Materials and methods: Computed tomography scans of 100 patients were examined. Axial, paraxial, and Panorex sections were analyzed using a dedicated software. Precise reference points were encoded to make the bone measurements clear and repeatable. Results: The total number of dental sites examined was 235. The mean available bone height was 13.32 ± 3.23 mm in first molars and 11.76 ± 2.82 mm in second molars. The inter-radicular septum was present in 86% out of cases in first molar sites and in 52% in second molar sites. The lingual cortex mean width, at the most coronal point, measured 1.41 ± 0.52 mm in first molar alveoli and 1.67 ± 0.66 mm in second molar alveoli. Conclusions: Proper clinical conditions, for scheduling a postextraction immediate implant placement surgery, involve the presence of 4 bone walls showing and sufficient height and width. The accurate knowledge of alveolus bone morphology of mandibular molars, prior extraction, could be an important guide to avoid potential failures due to nonideal anatomical features to fixture stabilization.
MeSH term(s)	Adult ; Alveolar Process/anatomy & histology ; Alveolar Process/diagnostic imaging ; Anatomic Landmarks ; Female ; Humans ; Immediate Dental Implant Loading ; Male ; Mandible/anatomy & histology ; Mandible/diagnostic imaging ; Molar/anatomy & histology ; Molar/diagnostic imaging ; Radiographic Image Interpretation, Computer-Assisted ; Radiography, Panoramic ; Software ; Tomography, X-Ray Computed ; Tooth Extraction
Language	English
Publishing date	2018-04-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1144907-x
ISSN	1538-2982 ; 1056-6163
ISSN (online)	1538-2982
ISSN	1056-6163
DOI	10.1097/ID.0000000000000757
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Article ; Online: Anatomical and Radiologic Evaluation of the Dimensions of Upper Molar Alveoli.

Agostinelli, Claudio / Agostinelli, Agnese / Berardini, Marco / Trisi, Paolo

Implant dentistry

2018 Volume 27, Issue 2, Page(s) 171–176

Abstract: Purpose: The aim of the present study was to analyze the alveolar bone morphology of the upper first and second molars. This analysis aims to evaluate the morphology of a hypothetical postextractive site in the upper molar area to diagnose the ... ...

Abstract	Purpose: The aim of the present study was to analyze the alveolar bone morphology of the upper first and second molars. This analysis aims to evaluate the morphology of a hypothetical postextractive site in the upper molar area to diagnose the possibility of immediate postextraction implant placement. Materials and methods: Cone-beam CT scans of 100 patients were examined. The measurements were made using a dedicated 3D software. Reference points were identified to allow clear and repeatable measurements. Results: The mean available height was 7.43 ± 3.40 mm for the upper first molars and 7.07 ± 3.09 mm for the upper second molars. The interradicular septum was present in first molars in 74% of cases and 44% of cases in upper second molars. Conclusions: In most cases, the alveolar sites of the upper first and second molars do not present ideal conditions for immediate implant insertion in a correct position. The primary stabilization of a standard-sized dental implant is often difficult because of the minimum apical bone available. In particular, the interradicular septum, which often represents the ideal fixture position, is rarely adequately represented. Preoperative cone-beam scan and the knowledge of anatomical measurements from the present analysis are fundamental before planning immediate postextractive implants in the upper molar area.
Language	English
Publishing date	2018-03-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1144907-x
ISSN	1538-2982 ; 1056-6163
ISSN (online)	1538-2982
ISSN	1056-6163
DOI	10.1097/ID.0000000000000747
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Article ; Online: Transapical access for thoracic endovascular aortic repair to elephant trunk completion.

Agostinelli, Andrea / Carino, Davide / Borrello, Bruno / Nicolini, Francesco

Interactive cardiovascular and thoracic surgery

2018 Volume 27, Issue 2, Page(s) 301–303

Abstract: The 2-stage elephant trunk procedure is widely used to treat extensive disease of the aortic arch and descending thoracic aorta. The 2nd stage of the procedure can be accomplished with both a standard surgical procedure and a retrograde transfemoral ... ...

Abstract	The 2-stage elephant trunk procedure is widely used to treat extensive disease of the aortic arch and descending thoracic aorta. The 2nd stage of the procedure can be accomplished with both a standard surgical procedure and a retrograde transfemoral endovascular approach using the dangling graft as proximal landing zone. However, in some patients, severe disease of iliofemoral vessels can prevent standard retrograde thoracic endovascular aortic repair (TEVAR). In such cases, an alternative route to gain endovascular access must be used. Herein, we report a case of anterograde cardiac transapical approach for TEVAR as a 2nd stage of an elephant trunk procedure.
MeSH term(s)	Aged ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic/diagnosis ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation/methods ; Computed Tomography Angiography ; Endovascular Procedures/methods ; Humans ; Male ; Treatment Outcome
Language	English
Publishing date	2018-03-14
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivy074
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Article: A Case of Type I Debranching Complicated by Anastomotic Pseudoaneurysm: Do Not Ask Too Much of the Ascending Aorta.

Carino, Davide / Molardi, Alberto / Gherli, Tiziano / Nicolini, Francesco / Agostinelli, Andrea

Aorta (Stamford, Conn.)

2019 Volume 7, Issue 2, Page(s) 63–66

Abstract: Treatment of aortic arch aneurysm with standard open surgery is technically demanding, and associated morbidity and mortality are not insignificant. In high-risk patients, hybrid procedures with debranching and reimplantation or bypass of the aortic arch ...

Abstract	Treatment of aortic arch aneurysm with standard open surgery is technically demanding, and associated morbidity and mortality are not insignificant. In high-risk patients, hybrid procedures with debranching and reimplantation or bypass of the aortic arch vessel followed by thoracic endovascular aortic repair (TEVAR) in the aortic arch represent a valid alternative to open surgery. However, when the ascending aorta is mildly dilated, the risk of retrograde dissection increases sharply. Here, we report a case of thoracic aortic aneurysm, with normal ascending aorta diameter, treated with Type I debranching and anterograde TEVAR complicated by anastomotic pseudoaneurysm and acute endocarditis, treated ultimately with ascending aortic repair and aortic valve replacement.
Language	English
Publishing date	2019-09-17
Publishing country	Germany
Document type	Journal Article
ISSN	2325-4637
ISSN	2325-4637
DOI	10.1055/s-0039-1688439
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