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  1. AU="Agrawal, Rohit Vijay"
  2. AU="Nakae, Mami"
  3. AU="Blake, Christine E"
  4. AU=Pareek Anil
  5. AU="Shokrollahi, Mitra"
  6. AU="Charles?Luce"
  7. AU="Denadai, Rafael"
  8. AU="Ambrosino, Teresa"
  9. AU=Antipova Tatiana
  10. AU="Moens, Pierre D J"
  11. AU="Abdel-Megied, Ahmed M."
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  13. AU="Marcos, Jose F"
  14. AU="Furr-Stimming, Erin"
  15. AU="Schüle, Birgit"
  16. AU="Travieso-González, Alejandro"
  17. AU=Turilli Emily Samuela
  18. AU="Rueckert, Erroll H"
  19. AU=Keestra-Gounder A. Marijke
  20. AU="María José Endara"
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  22. AU="Shirvanian, Moein"
  23. AU="Capaldo, Bianca D"
  24. AU="Matose, Takunda"
  25. AU=Plouffe Brian D.
  26. AU=Kuter David J
  27. AU="Moore, I D"
  28. AU="Schreibing, Felix"
  29. AU=Kang Keunsoo
  30. AU="de Pedro-Múñez, Álvaro"

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  1. Artikel ; Online: Pentoxifylline therapy for persistent hepatopulmonary syndrome after liver transplantation.

    Tan, Yi Wei / Agrawal, Rohit Vijay / Pan, Terry Ling Te / Muthiah, Mark Dhinesh / Teo, Felicia Su Wei / Wong, Weng Hoa

    Singapore medical journal

    2023  

    Sprache Englisch
    Erscheinungsdatum 2023-08-17
    Erscheinungsland India
    Dokumenttyp Letter
    ZDB-ID 604319-7
    ISSN 2737-5935 ; 0037-5675
    ISSN (online) 2737-5935
    ISSN 0037-5675
    DOI 10.4103/singaporemedj.SMJ-2021-246
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  2. Artikel ; Online: Essential ICU drug shortages for COVID-19: what can frontline clinicians do?

    Siow, Wen Ting / Tang, Simeon H / Agrawal, Rohit Vijay / Tan, Addy Y H / See, Kay Choong

    Critical care (London, England)

    2020  Band 24, Heft 1, Seite(n) 260

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; China ; Coronavirus Infections ; Critical Care ; Humans ; Intensive Care Units ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-05-26
    Erscheinungsland England
    Dokumenttyp Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-02971-x
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  3. Artikel: Essential ICU drug shortages for COVID-19: what can frontline clinicians do?

    Siow, Wen Ting / Tang, Simeon H / Agrawal, Rohit Vijay / Tan, Addy Y H / See, Kay Choong

    Crit Care

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #378156
    Datenquelle COVID19

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  4. Artikel ; Online: Essential ICU drug shortages for COVID-19

    Siow, Wen Ting / Tang, Simeon H. / Agrawal, Rohit Vijay / Tan, Addy Y. H. / See, Kay Choong

    Critical Care

    what can frontline clinicians do?

    2020  Band 24, Heft 1

    Schlagwörter Critical Care and Intensive Care Medicine ; covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2041406-7
    ISSN 1364-8535
    ISSN 1364-8535
    DOI 10.1186/s13054-020-02971-x
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  5. Artikel ; Online: Ideal Sequence of Didactic Lectures and Simulation in Teaching Transesophageal Echocardiography Among Anesthesiologists.

    Thampi, Swapna / Lee, Chang Chuan Melvin / Agrawal, Rohit Vijay / Ashokka, Balakrishnan / Ti, Lian Kah / Paranjothy, Suresh / Ponnamperuma, Gominda G

    Journal of cardiothoracic and vascular anesthesia

    2019  Band 34, Heft 5, Seite(n) 1244–1249

    Abstract: Objective: Performing a basic perioperative transesophageal echocardiography (TEE) requires 3-dimensional knowledge of cardiac anatomy, psychomotor skills, and image interpretation. Commonly, lectures followed by simulation sequence is used for teaching ...

    Abstract Objective: Performing a basic perioperative transesophageal echocardiography (TEE) requires 3-dimensional knowledge of cardiac anatomy, psychomotor skills, and image interpretation. Commonly, lectures followed by simulation sequence is used for teaching TEE. Differences may occur among learners when this sequencing of instructional components is altered. The authors investigated the ideal sequence of lectures and simulation in teaching basic perioperative TEE.
    Design: Prospective randomized comparative study.
    Setting: Simulation room in a large academy tertiary care center.
    Participants: Noncardiac anesthesiologists in Singapore with no prior knowledge of TEE.
    Intervention: Comparison of acquisition and retention of knowledge and skills between the lecture followed by simulation group (LS) and the simulation followed by lecture (SL) group.
    Measurements and main results: Knowledge was assessed using multiple-choice questions (MCQs) and skills using a skill test. The primary outcome measured was the MCQ scores (post-course and retest) and the skill test scores (post-course and retest). Of the 43 anesthesiologists who were recruited, 22 were randomized into the LS group and 21 to the SL group. All participants took pre-course and post-course MCQs and post-course skill tests. Post-tests were repeated 1 month after the course to assess retention. There was no significant difference in the post-course MCQ (85.87% v 81.82%) and skill test scores (85.78% v 81.55%) between the SL and LS groups, respectively. The SL group demonstrated significantly better retention of knowledge at 1 month (MCQ score 83.5% v 72.73%; p = 0.003) and skills (skill test score 85.32% v 1.90%; p = 0.016) than the other.
    Conclusion: This study showed that, for retention (at 1 month) of both knowledge and skills, it is preferable to teach practical skills followed by theoretical knowledge to anesthesiologists who are complete novices to TEE.
    Mesh-Begriff(e) Anesthesiologists ; Clinical Competence ; Echocardiography, Transesophageal ; Humans ; Prospective Studies ; Singapore ; Teaching
    Sprache Englisch
    Erscheinungsdatum 2019-12-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2019.12.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: A novel hospital capacity versus clinical justification triage score (CCTS) for prioritization of spinal surgeries in the "new normal state" of the COVID-19 pandemic.

    Liu, Gabriel / Tan, Jun-Hao / Hey, Hwee Weng Dennis / Lau, Leok Lim / Thambiah, Joseph / Kumar, Naresh / Tan, Jonathan / Ruiz, John / Nga, Vincent / Lwin, Sein / Teo, Kejia / Ning, Chou / Agrawal, Rohit Vijay / Ng, Bryan / Wong, Weng Hoa / Yeo, Tseng Tsai / Wong, Hee-Kit

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

    2021  Band 30, Heft 5, Seite(n) 1247–1260

    Abstract: Introduction: During the Coronavirus disease 2019 outbreak, while healthcare systems and hospitals are diverting their resources to combat the pandemic, patients who require spinal surgeries continue to accumulate. The aim of this study is to describe a ...

    Abstract Introduction: During the Coronavirus disease 2019 outbreak, while healthcare systems and hospitals are diverting their resources to combat the pandemic, patients who require spinal surgeries continue to accumulate. The aim of this study is to describe a novel hospital capacity versus clinical justification triage score (CCTS) to prioritize patients who require surgery during the "new normal state" of the COVID-19 pandemic.
    Methodology: A consensus study using the Delphi technique was carried out among clinicians from the Orthopaedic Surgery, Neurosurgery, and Anaesthesia departments. Three rounds of consensus were carried out via survey and Webinar discussions.
    Results: A 50-points score system consisting of 4 domains with 4 subdomains was formed. The CCTS were categorized into the hospital capacity, patient factors, disease severity, and surgery complexity domains. A score between 30 and 50 points indicated that the proposed operation should proceed without delay. A score of less than 20 indicates that the proposed operation should be postponed. A score between 20 and 29 indicates that the surgery falls within a grey area where further discussion should be undertaken to make a joint justification for approval of surgery.
    Conclusion: This study is a proof of concept for the novel CCTS scoring system to prioritize surgeries to meet the rapidly changing demands of the COVID-19 pandemic. It offers a simple and objective method to stratify patients who require surgery and allows these complex and difficult decisions to be unbiased and made transparently among surgeons and hospital administrators.
    Mesh-Begriff(e) COVID-19 ; Hospitals ; Humans ; Pandemics ; SARS-CoV-2 ; Triage
    Sprache Englisch
    Erscheinungsdatum 2021-01-02
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1115375-1
    ISSN 1432-0932 ; 0940-6719
    ISSN (online) 1432-0932
    ISSN 0940-6719
    DOI 10.1007/s00586-020-06679-y
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  7. Artikel ; Online: Ensuring Sustainability of Continuous Kidney Replacement Therapy in the Face of Extraordinary Demand: Lessons From the COVID-19 Pandemic.

    Chua, Horng-Ruey / MacLaren, Graeme / Choong, Lina Hui-Lin / Chionh, Chang-Yin / Khoo, Benjamin Zhi En / Yeo, See-Cheng / Sewa, Duu-Wen / Ng, Shin-Yi / Choo, Jason Chon-Jun / Teo, Boon-Wee / Tan, Han-Khim / Siow, Wen-Ting / Agrawal, Rohit Vijay / Tan, Chieh-Suai / Vathsala, Anantharaman / Tagore, Rajat / Seow, Terina Ying-Ying / Khatri, Priyanka / Hong, Wei-Zhen /
    Kaushik, Manish

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2020  Band 76, Heft 3, Seite(n) 392–400

    Abstract: With the exponential surge in patients with coronavirus disease 2019 (COVID-19) worldwide, the resources needed to provide continuous kidney replacement therapy (CKRT) for patients with acute kidney injury or kidney failure may be threatened. This ... ...

    Abstract With the exponential surge in patients with coronavirus disease 2019 (COVID-19) worldwide, the resources needed to provide continuous kidney replacement therapy (CKRT) for patients with acute kidney injury or kidney failure may be threatened. This article summarizes subsisting strategies that can be implemented immediately. Pre-emptive weekly multicenter projections of CKRT demand based on evolving COVID-19 epidemiology and routine workload should be made. Corresponding consumables should be quantified and acquired, with diversification of sources from multiple vendors. Supply procurement should be stepped up accordingly so that a several-week stock is amassed, with administrative oversight to prevent disproportionate hoarding by institutions. Consumption of CKRT resources can be made more efficient by optimizing circuit anticoagulation to preserve filters, extending use of each vascular access, lowering blood flows to reduce citrate consumption, moderating the CKRT intensity to conserve fluids, or running accelerated KRT at higher clearance to treat more patients per machine. If logistically feasible, earlier transition to intermittent hemodialysis with online-generated dialysate, or urgent peritoneal dialysis in selected patients, may help reduce CKRT dependency. These measures, coupled to multicenter collaboration and a corresponding increase in trained medical and nursing staffing levels, may avoid downstream rationing of care and save lives during the peak of the pandemic.
    Mesh-Begriff(e) Acute Kidney Injury/epidemiology ; Acute Kidney Injury/therapy ; Anticoagulants/administration & dosage ; Anticoagulants/supply & distribution ; Betacoronavirus ; COVID-19 ; Continuous Renal Replacement Therapy/instrumentation ; Continuous Renal Replacement Therapy/trends ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Dialysis Solutions/administration & dosage ; Dialysis Solutions/supply & distribution ; Health Services Needs and Demand/trends ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Renal Insufficiency/epidemiology ; Renal Insufficiency/therapy ; SARS-CoV-2
    Chemische Substanzen Anticoagulants ; Dialysis Solutions
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2020.05.008
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  8. Artikel: Ensuring Sustainability of Continuous Kidney Replacement Therapy in the Face of Extraordinary Demand: Lessons From the COVID-19 Pandemic

    Chua, Horng-Ruey / MacLaren, Graeme / Choong, Lina Hui-Lin / Chionh, Chang-Yin / Khoo, Benjamin Zhi En / Yeo, See-Cheng / Sewa, Duu-Wen / Ng, Shin-Yi / Choo, Jason Chon-Jun / Teo, Boon-Wee / Tan, Han-Khim / Siow, Wen-Ting / Agrawal, Rohit Vijay / Tan, Chieh-Suai / Vathsala, Anantharaman / Tagore, Rajat / Seow, Terina Ying-Ying / Khatri, Priyanka / Hong, Wei-Zhen /
    Kaushik, Manish

    Am J Kidney Dis

    Abstract: With the exponential surge in patients with coronavirus disease 2019 (COVID-19) worldwide, the resources needed to provide continuous kidney replacement therapy (CKRT) for patients with acute kidney injury or kidney failure may be threatened. This ... ...

    Abstract With the exponential surge in patients with coronavirus disease 2019 (COVID-19) worldwide, the resources needed to provide continuous kidney replacement therapy (CKRT) for patients with acute kidney injury or kidney failure may be threatened. This article summarizes subsisting strategies that can be implemented immediately. Pre-emptive weekly multicenter projections of CKRT demand based on evolving COVID-19 epidemiology and routine workload should be made. Corresponding consumables should be quantified and acquired, with diversification of sources from multiple vendors. Supply procurement should be stepped up accordingly so that a several-week stock is amassed, with administrative oversight to prevent disproportionate hoarding by institutions. Consumption of CKRT resources can be made more efficient by optimizing circuit anticoagulation to preserve filters, extending use of each vascular access, lowering blood flows to reduce citrate consumption, moderating the CKRT intensity to conserve fluids, or running accelerated KRT at higher clearance to treat more patients per machine. If logistically feasible, earlier transition to intermittent hemodialysis with online-generated dialysate, or urgent peritoneal dialysis in selected patients, may help reduce CKRT dependency. These measures, coupled to multicenter collaboration and a corresponding increase in trained medical and nursing staffing levels, may avoid downstream rationing of care and save lives during the peak of the pandemic.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #526769
    Datenquelle COVID19

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  9. Artikel ; Online: Ensuring Sustainability of Continuous Kidney Replacement Therapy in the Face of Extraordinary Demand

    Chua, Horng-Ruey / MacLaren, Graeme / Choong, Lina Hui-Lin / Chionh, Chang-Yin / Khoo, Benjamin Zhi En / Yeo, See-Cheng / Sewa, Duu-Wen / Ng, Shin-Yi / Choo, Jason Chon-Jun / Teo, Boon-Wee / Tan, Han-Khim / Siow, Wen-Ting / Agrawal, Rohit Vijay / Tan, Chieh-Suai / Vathsala, Anantharaman / Tagore, Rajat / Seow, Terina Ying-Ying / Khatri, Priyanka / Hong, Wei-Zhen /
    Kaushik, Manish

    American Journal of Kidney Diseases

    Lessons From the COVID-19 Pandemic

    2020  Band 76, Heft 3, Seite(n) 392–400

    Schlagwörter Nephrology ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2020.05.008
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  10. Artikel ; Online: Can there be a place for intraoperative salvaged blood in spine tumor surgery?

    Kumar, Naresh / Ahmed, Qasim / Lee, Victor K M / Chen, Yongsheng / Zaw, Aye Sandar / Goy, Raymond / Agrawal, Rohit Vijay / Dhewar, Aisha Naheed / Wong, Hee Kit

    Annals of surgical oncology

    2014  Band 21, Heft 7, Seite(n) 2436–2443

    Abstract: Background: Intraoperative cell salvage (IOCS) has been used in musculoskeletal surgery extensively. However, it has never found its place in musculoskeletal oncologic surgery. We have conducted the first-ever study to evaluate the feasibility of IOCS ... ...

    Abstract Background: Intraoperative cell salvage (IOCS) has been used in musculoskeletal surgery extensively. However, it has never found its place in musculoskeletal oncologic surgery. We have conducted the first-ever study to evaluate the feasibility of IOCS in combination with a leucocyte-depletion filter (LDF) in metastatic spine tumor surgery. This was to pave the path for use of IOCS-LDF in musculoskeletal oncologic surgery.
    Methods: Patients with a known primary epithelial tumor, who were offered surgery for metastatic spinal disease, were recruited. Blood samples were collected at three different stages during the surgery: from the operative field before IOCS processing, after IOCS processing, and after IOCS-LDF processing. Three separate samples (5 mL each) were taken at each stage. Samples were examined using immunohistochemical monoclonal antibodies to identify tumor cells of epithelial origin.
    Results: Of 30 patients in the study, 6 were excluded for not fulfilling the inclusion criteria, leaving 24 patients. Malignant tumor cells were detected in the samples from the operative field before IOCS processing in eight patients and in the samples from the transfusion bag after IOCS processing in three patients. No viable malignant cell was detectable in any of the blood samples after passage through both IOCS and LDF.
    Conclusions: The findings support the notion that the IOCS-LDF combination works effectively in eliminating tumor cells from salvaged blood, so this technique can be applied successfully in spine tumor surgery. This concept can then further be extended to whole musculoskeletal tumor surgery and other oncologic surgeries with further appropriate clinical studies.
    Mesh-Begriff(e) Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Humans ; Intraoperative Care ; Leukocyte Reduction Procedures ; Male ; Middle Aged ; Neoplasm Staging ; Neoplasms, Glandular and Epithelial/pathology ; Neoplasms, Glandular and Epithelial/surgery ; Operative Blood Salvage/methods ; Prognosis ; Prospective Studies ; Spinal Neoplasms/secondary ; Spinal Neoplasms/surgery
    Sprache Englisch
    Erscheinungsdatum 2014-07
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-014-3569-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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