Article ; Online: Sequential serological surveys in the early stages of the coronavirus disease epidemic: limitations and perspectives.
Revista da Sociedade Brasileira de Medicina Tropical
2020 Volume 53, Page(s) e20200351
Abstract: Introduction: Estimates of the number of individuals infected by severe acute respiratory syndrome coronavirus 2 are important for health planning and establishment of expectations regarding herd immunity.: Methods: Seven testing rounds of a ... ...
Abstract | Introduction: Estimates of the number of individuals infected by severe acute respiratory syndrome coronavirus 2 are important for health planning and establishment of expectations regarding herd immunity. Methods: Seven testing rounds of a serological survey were conducted at 1-week intervals between April 19 and May 31, 2020 in Teresina municipality. RESULTS Over the 7 weeks, serological positivity increased from 0.56% (95% confidence interval [CI]: 0.18%-1.30%) to 8.33% (95% CI: 6.61%-10.33%), representing 33-53 persons infected for each reported case. Conclusions: Serological screening may be an important tool for understanding the immunity of a population and planning community interventions. |
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MeSH term(s) | Asymptomatic Diseases/epidemiology ; Betacoronavirus/immunology ; Brazil/epidemiology ; COVID-19 ; Confidence Intervals ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; False Positive Reactions ; Humans ; Immunity, Herd ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; SARS-CoV-2 ; Sensitivity and Specificity ; Seroepidemiologic Studies |
Keywords | covid19 |
Language | English |
Publishing date | 2020-07-03 |
Publishing country | Brazil |
Document type | Journal Article |
ZDB-ID | 1038126-0 |
ISSN | 1678-9849 ; 0037-8682 |
ISSN (online) | 1678-9849 |
ISSN | 0037-8682 |
DOI | 10.1590/0037-8682-0351-2020 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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