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  1. Article: Obliteration of

    Jafar, Mohammed / Ahmad Khan, Mohd Sajjad / Akbar, Mohammad Jamal / AlSaihaty, Hadi Saleem / Alasmari, Sultan Saad

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29246

    Abstract: Thyme oil (TO) is a valuable essential oil believed to possess a variety of bioactivities, including antibacterial, anticancer, and antioxidant properties. These attributes grant TO the excellent capability to treat a wide range of diseases, particularly ...

    Abstract Thyme oil (TO) is a valuable essential oil believed to possess a variety of bioactivities, including antibacterial, anticancer, and antioxidant properties. These attributes grant TO the excellent capability to treat a wide range of diseases, particularly the effective eradication of
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Phytomedicine from Middle Eastern Countries: An Alternative Remedy to Modern Medicine against

    Alam, Mohammad Zubair / Ahmad Khan, Mohd Sajjad

    Evidence-based complementary and alternative medicine : eCAM

    2021  Volume 2021, Page(s) 6694876

    Abstract: ... ...

    Abstract Candida
    Language English
    Publishing date 2021-07-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2021/6694876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Biosurfactants: Potential applications as immunomodulator drugs.

    Sajid, Mohammad / Ahmad Khan, Mohd Sajjad / Singh Cameotra, Swaranjit / Safar Al-Thubiani, Abdullah

    Immunology letters

    2020  Volume 223, Page(s) 71–77

    Abstract: Biosurfactants (BSs) molecules are classically branded as emulsifiers of hydrocarbon compounds and are extensively applied in several fields including pharmaceutics, food processing, biodegradation, bioremediation, cosmetics, and pest control management. ...

    Abstract Biosurfactants (BSs) molecules are classically branded as emulsifiers of hydrocarbon compounds and are extensively applied in several fields including pharmaceutics, food processing, biodegradation, bioremediation, cosmetics, and pest control management. Due to the amphiphilic and surface-active properties, BS interacts with lipid membranes of the cell and alters its physio-chemical nature. As a result, various biological functions of the target cells are lost. In recent times, several studies have shown antimicrobial, antiviral, and anticancer potentials of BS molecules. BS primarily destroy bacterial cells by directly disrupting the integrity of the plasma membrane or cell wall. Whereas, their antiviral action seems to be due to their physicochemical interaction with the virus lipid envelope. However, antiproliferative potency of BSs make them a potential anticancer agent. BS can induce cell cycle arrest, apoptosis and metastasis arrest in tumour cells with no influence on non-tumour cells. Interestingly, BS molecules also demonstrate immunomodulatory activities either by suppression or activation of immune system. The advantages of BS over their chemical counterparts are their biocompatibility, high biodegradability, high specificity and low toxicity. Moreover, chemical diversity, environmentally friendly nature and, suitability for large-scale production has bestowed BS many future applications. This review presents, in a systematic manner, the interference of BS of various classes including glycolipids, phospholipids and lipopeptides with the activities or mechanism of action of immune response. Also, we shed lights on how such biological activities of BSs make them a new class of therapeutic molecules for combating various immune disorders.
    MeSH term(s) Animals ; Biocompatible Materials/therapeutic use ; Biological Products/therapeutic use ; Humans ; Immune System Diseases/drug therapy ; Immunity ; Immunologic Factors/therapeutic use ; Immunosuppression ; Lipid Metabolism ; Surface-Active Agents/therapeutic use
    Chemical Substances Biocompatible Materials ; Biological Products ; Immunologic Factors ; Surface-Active Agents
    Language English
    Publishing date 2020-04-30
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 445150-8
    ISSN 1879-0542 ; 0165-2478
    ISSN (online) 1879-0542
    ISSN 0165-2478
    DOI 10.1016/j.imlet.2020.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1512: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Virulence and biofilms as promising targets in developing antipathogenic drugs against candidiasis.

    Ahmad Khan, Mohd Sajjad / Alshehrei, Fatimah / Al-Ghamdi, Saleh Bakheet / Bamaga, Majid Abdullah / Al-Thubiani, Abdullah Safar / Alam, Mohammad Zubair

    Future science OA

    2020  Volume 6, Issue 2, Page(s) FSO440

    Abstract: ... Candida ... ...

    Abstract Candida albicans
    Language English
    Publishing date 2020-02-03
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2056-5623
    ISSN 2056-5623
    DOI 10.2144/fsoa-2019-0027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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