LIVIVO - Search results -

Search results

Result 1 - 10 of total 34

Search options

Article ; Online: Diagnostic Evaluation of Pulmonary Hypertension

Suneesh Anand / Ahmed Sadek / Anjali Vaidya / Estefania Oliveros

Journal of Clinical Medicine, Vol 12, Iss 23, p

A Comprehensive Approach for Primary Care Physicians

2023 Volume 7309

Abstract: Pulmonary hypertension (PH) is a disorder involving a heterogeneous group of medical conditions encompassing several cardiopulmonary illnesses. Implementing new diagnostic criteria for PH in conjunction with multimodality diagnostic tools is crucial for ... ...

Abstract	Pulmonary hypertension (PH) is a disorder involving a heterogeneous group of medical conditions encompassing several cardiopulmonary illnesses. Implementing new diagnostic criteria for PH in conjunction with multimodality diagnostic tools is crucial for accurate and early recognition of this life-threatening form of right heart failure. This should streamline early referrals to accredited PH centers, with a goal to rapidly institute targeted therapy in order to optimize prognosis.
Keywords	pulmonary hypertension ; pulmonary vascular disease ; right heart failure ; Medicine ; R
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Capped flexosomes for prominent anti-inflammatory activity: development, optimization, and ex vivo and in vivo assessments.

Ahmed, Sadek / Aziz, Diana E / Sadek, Mohamed A / Tawfik, Mai Ahmed

Drug delivery and translational research

2024

Abstract: This study aimed to formulate diacerein (DCN)-loaded flexosomes for enhanced efficacy against osteoarthritis. A ... ...

Abstract	This study aimed to formulate diacerein (DCN)-loaded flexosomes for enhanced efficacy against osteoarthritis. A 2
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2590155-2
ISSN	2190-3948 ; 2190-393X
ISSN (online)	2190-3948
ISSN	2190-393X
DOI	10.1007/s13346-024-01522-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Ocular Drug Delivery: a Comprehensive Review.

Ahmed, Sadek / Amin, Maha M / Sayed, Sinar

AAPS PharmSciTech

2023 Volume 24, Issue 2, Page(s) 66

Abstract: The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration is an interest of scientists for many decades. Their difficult mission is to ...

Abstract	The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration is an interest of scientists for many decades. Their difficult mission is to prolong drug residence time and guarantee an appropriate ocular permeation. Several ocular obstacles oppose effective drug delivery such as precorneal, corneal, and blood-corneal barriers. Routes for ocular delivery include topical, intravitreal, intraocular, juxtascleral, subconjunctival, intracameral, and retrobulbar. More than 95% of marketed products exists in liquid state. However, other products could be in semi-solid (ointments and gels), solid state (powder, insert and lens), or mixed (in situ gel). Nowadays, attractiveness to nanotechnology-based carries is resulted from their capabilities to entrap both hydrophilic and lipophilic drugs, enhance ocular permeability, sustain residence time, improve drug stability, and augment bioavailability. Different in vitro, ex vivo, and in vivo characterization approaches help to predict the outcomes of the constructed nanocarriers. This review aims to clarify anatomy of the eye, various ocular diseases, and obstacles to ocular delivery. Moreover, it studies the advantages and drawbacks of different ocular routes of administration and dosage forms. This review also discusses different nanostructured platforms and their characterization approaches. Strategies to enhance ocular bioavailability are also explained. Finally, recent advances in ocular delivery are described.
MeSH term(s)	Humans ; Administration, Ophthalmic ; Drug Delivery Systems ; Cornea ; Administration, Topical ; Permeability
Language	English
Publishing date	2023-02-14
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2052070-0
ISSN	1530-9932 ; 1530-9932
ISSN (online)	1530-9932
ISSN	1530-9932
DOI	10.1208/s12249-023-02516-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration.

Ahmed, Sadek / Amin, Maha M / Sayed, Sinar

Drug delivery

2023 Volume 30, Issue 1, Page(s) 2179129

Abstract: This review aims to comprehensively highlight the recent nanosystems enclosing Fenticonazole nitrate (FTN) and to compare between them regarding preparation techniques, studied factors and responses. Moreover, the optimum formulae were compared in terms ... ...

Abstract	This review aims to comprehensively highlight the recent nanosystems enclosing Fenticonazole nitrate (FTN) and to compare between them regarding preparation techniques, studied factors and responses. Moreover, the optimum formulae were compared in terms of
MeSH term(s)	Rats ; Animals ; Female ; Drug Delivery Systems/methods ; Antifungal Agents/pharmacology ; Administration, Cutaneous ; Nitrates ; Rats, Wistar ; Imidazoles ; Surface-Active Agents/chemistry ; Particle Size ; Drug Carriers
Chemical Substances	Antifungal Agents ; fenticonazole (QG05NRB077) ; Nitrates ; Imidazoles ; Surface-Active Agents ; Drug Carriers
Language	English
Publishing date	2023-02-14
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	1213261-5
ISSN	1521-0464 ; 1071-7544
ISSN (online)	1521-0464
ISSN	1071-7544
DOI	10.1080/10717544.2023.2179129
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4252: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The efficiency of intra-articular injection of silver nanoparticles (AgNPs) on repair of experimentally induced avascular meniscal tear in dogs

Ahmed Sadek / Sary Kh. Abdel-ghaffar / Mohamed Semieka / Samia Moustafa

Journal of Advanced Veterinary Research, Vol 14, Iss

2023 Volume 1

Abstract: Meniscal tears in the inner avascular area have been reported as a common cause of disability in dogs that associated with failure of healing process due to their limited vascularity. In spite of various sterategies were reported for treatment of such ... ...

Abstract	Meniscal tears in the inner avascular area have been reported as a common cause of disability in dogs that associated with failure of healing process due to their limited vascularity. In spite of various sterategies were reported for treatment of such tears, their clinical use was limited. Therefore, different biomaterials have been assessed to stimulate regeneration of avascular meniscal tears. Currently, silver nanoparticles (AgNPs) enormously involved in biomedicine including tissue regeneration, drug delivary, and antibacterial applications. Thus, AgNPs was fabricated in the present study to investigate its potential to induce and support meniscal healing process in an avascular meniscal tear model. The nanomaterial was synthesized and characterized using transmission electron microscope (TEM). Next, a full thickness longitudinal meniscal tear was created in the avascular zone and either left empty or treated with AgNPs. Animals were monitored clinically at weeks 3, 6, 9, and 12 weeks after surgery for lameness parameters including lameness during walking, pain on manipulation, range of motion, and functional disability. Additionally, the harvested menisci were examined macroscopically and histologically at 4, 8, and 12 weeks. The designed material revealed improved clinical outcomes compared to control group. The gross and histological observations proved that the meniscal healing was stimulated in the AgNPs-treated group in comparison to control one, where the AgNPs-treated tear sites were filled with reparative tissue. In conclusion, AgNPs nanomaterial has a promoting effect on the process of meniscal tissue healing in the avascular region, proving that AgNPs is a promising material for meniscal tissue regeneration.
Keywords	Silver Nanoparticles ; Meniscal tears ; Meniscal healing ; Veterinary medicine ; SF600-1100
Subject code	630
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Assiut University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Comparison between the regenerative potential of bone marrow aspirate (BMA) and platelet-rich plasma (PRP) on healing of canine meniscal tear

Ahmed Sadek / Sary Kh. Abdel-ghaffar / Mahmoud Rushdi / Mohamed Semieka / Samia Moustafa

Journal of Advanced Veterinary Research, Vol 14, Iss

2023 Volume 1

Abstract: Repair of meniscal tears in the avascular zone represents an obstacle for orthopedic surgeons. Several therapeutic methods have been suggested to mange these tears including meniscectomy and meniscal allografts; however, their clinical application was ... ...

Abstract	Repair of meniscal tears in the avascular zone represents an obstacle for orthopedic surgeons. Several therapeutic methods have been suggested to mange these tears including meniscectomy and meniscal allografts; however, their clinical application was restricted due to their disadvantages. These limitations inspired the necessity to develop products that possess the ability to initiate healing in such avascular tears. Hence, the goal of the current study is to assess and compare the regenerative capability of bone marrow aspirate (BMA) and platelet-rich plasma (PRP) to enhance repair of avascular meniscal tears. After preparation of BMA and PRP, meniscal tear was conducted in the inner avascular zones in dogs and left untreated as control or treated with either BMA or PRP. Clinical observation of weight bearing, lameness, pain on manipulation, gait, and functional disability were investigated after 3, 6, 9, and 12 weeks of surgery. In addition, gross and histological evaluations were performed at weeks 4, 8, and 12 after surgery. Both materials demonstrated a positive improvement in clinical observations compared to the control group. Furthermore, repair of meniscal tears was stimulated in tears treated with either BMA or PRP with better gross and histological outcomes in PRP-treated group than BMA-treated group. To conclude, our findings showed that BMA and PRP possess the potential to enhance the healing process of meniscal tears in the inner avascular region with the superiority of PRP.
Keywords	bone marrow stromal cells ; PRP ; Meniscal tear ; Meniscal healing ; Veterinary medicine ; SF600-1100
Subject code	630
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Assiut University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Caprine arthritis and encephalitis virus infection in goats of Bangladesh: Serological detection and its associated risk factors.

Rahman, Md Habibur / Akther, Sonia / Alam, Md Shahin / Ali, Md Zulfekar / Ahmed, Sadek

Veterinary world

2023 Volume 16, Issue 11, Page(s) 2256–2262

Abstract: Background and aim: Caprine arthritis and encephalitis (CAE) is a multisystemic persistent viral disease of goat that causes significant economic losses to the farmers and livestock sector. However, no information in this country is available regarding ... ...

Abstract	Background and aim: Caprine arthritis and encephalitis (CAE) is a multisystemic persistent viral disease of goat that causes significant economic losses to the farmers and livestock sector. However, no information in this country is available regarding CAE virus (CAEV) infection. Therefore, this study aimed to estimate the seroprevalence of CAEV infection among the goat population in the selected goat-prone districts in Bangladesh and to identify the associated risk factors of the disease. Materials and methods: From July 2021 to June 2022, 446 goat serum samples were randomly collected from the study area. Goat owners were interviewed using a pretested questionnaire to determine the risk factors. A commercial indirect enzyme-linked immunosorbent assay kit was used to screen blood serum for CAEV antibodies. Logistic regression models were used to analyze risk factors and serological data to identify the potential risk factors. Results: Out of 446 serum samples, 19 samples were seropositive against CAEV. The overall seroprevalence was 4.26% (95% confidence interval [CI]: 2.58-6.57). The multivariable logistic regression model identified sex (Female; odds ratio [OR]: 3.98; 95% CI: 1.13-13.95), animal age (12-48 months; OR: 4.93, 95% CI: 0.63-38.13), and biosecurity status (Poor biosecurity; OR: 1.66, 95% CI: 0.46-5.92) as potential risk factors for CAEV seropositivity. Conclusion: This study revealed the serological detection of CAEV in Bangladeshi goats where seroprevalence is found to be relatively low. To eradicate the disease, screening and culling of infected goats from the herd might be implemented.
Language	English
Publishing date	2023-11-11
Publishing country	India
Document type	Journal Article
ZDB-ID	2456277-4
ISSN	2231-0916 ; 0972-8988
ISSN (online)	2231-0916
ISSN	0972-8988
DOI	10.14202/vetworld.2023.2256-2262
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Pronounced capping effect of olaminosomes as nanostructured platforms in ocular candidiasis management.

Ahmed, Sadek / Amin, Maha M / El-Korany, Sarah Mohamed / Sayed, Sinar

Drug delivery

2022 Volume 29, Issue 1, Page(s) 2945–2958

Abstract: The aim of this study was to formulate and boost ocular targeting of Fenticonazole Nitrate (FTN)-loaded olaminosomes in order to improve drug corneal permeation and candidiasis treatment. Olaminosomes were formulated by ethanol injection technique ... ...

Abstract	The aim of this study was to formulate and boost ocular targeting of Fenticonazole Nitrate (FTN)-loaded olaminosomes in order to improve drug corneal permeation and candidiasis treatment. Olaminosomes were formulated by ethanol injection technique applying a central composite design. The independent variables were: span 80 amount (mg) (A), oleylamine concentration (mg%) (B) and oleic acid: drug ratio (C). The dependent responses were: percent entrapment efficiency (EE %), particle size (PS), poly-dispersity index (PDI), zeta potential (ZP) and
MeSH term(s)	Administration, Ophthalmic ; Antifungal Agents/pharmacology ; Candidiasis/drug therapy ; Eye Infections, Fungal/drug therapy ; Humans ; Nitrates
Chemical Substances	Antifungal Agents ; Nitrates
Language	English
Publishing date	2022-11-02
Publishing country	England
Document type	Journal Article
ZDB-ID	1213261-5
ISSN	1521-0464 ; 1071-7544
ISSN (online)	1521-0464
ISSN	1071-7544
DOI	10.1080/10717544.2022.2120926
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4252: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation,

Ahmed, Sadek / Amin, Maha M / El-Korany, Sarah Mohamed / Sayed, Sinar

Drug delivery

2022 Volume 29, Issue 1, Page(s) 2428–2441

Abstract: The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-loaded novasomes aiming to enhance drug corneal penetration and to improve its antifungal activity. Ethanol injection was used to formulate FTN-loaded novasomes ... ...

Abstract	The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-loaded novasomes aiming to enhance drug corneal penetration and to improve its antifungal activity. Ethanol injection was used to formulate FTN-loaded novasomes adopting a central composite design. The researched factors were: stearic acid concentration (g%) (A), span 80: drug ratio (B) and cholesterol amount (mg) (C), and their effects on percent entrapment efficiency (EE%), particle size (PS), poly-dispersity index (PDI), zeta potential (ZP), and
MeSH term(s)	Antifungal Agents/pharmacology ; Candidiasis ; Drug Carriers ; Eye Infections, Fungal/drug therapy ; Humans ; Imidazoles ; Nitrates ; Particle Size
Chemical Substances	Antifungal Agents ; Drug Carriers ; Imidazoles ; Nitrates ; fenticonazole (QG05NRB077)
Language	English
Publishing date	2022-08-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1213261-5
ISSN	1521-0464 ; 1071-7544
ISSN (online)	1521-0464
ISSN	1071-7544
DOI	10.1080/10717544.2022.2103600
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4252: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Prevalence and Antibiogram profiles of STEC strains isolated from raw cow's milk in New-Valley Governorate, Egypt

Sotohy Ahmed Mohamed / Ehsan A. Hassan / Amgad A. Ezzat / Ahmed Sadek

SVU- International Journal of Veterinary Sciences. 2022 Mar., v. 5, no. 1

2022

Abstract: A cross sectional study was conducted to isolate and identify Shiga toxinproducing Escherichia coli (STEC) from raw cow milk. A total of 267 milk samples were collected from apparently healthy cattle in 7 different dairy farms. Thirty-nine STEC isolate ... ...

Abstract	A cross sectional study was conducted to isolate and identify Shiga toxinproducing Escherichia coli (STEC) from raw cow milk. A total of 267 milk samples were collected from apparently healthy cattle in 7 different dairy farms. Thirty-nine STEC isolate were identified out of 86-positive E. coli strains (56.98%). The prevalence of E. coli and STEC was 32.2% and 18.4%, respectively. Antimicrobial susceptibility of the isolated STEC was determined by disc diffusion method. A total of 16 antimicrobials of seven antimicrobial classes were used. Commercially available antibiotic disc namely aminoglycosides [Erythromycin (15 μg), Clindamycin (2μg, Kanamycin (30 μg, Amikacin (30 μg) , Gentamicin (10 μg), cephalosporins (Cefepime (30 μg, Cefotaxime (30μg), Cefazolin (30μg], Fluoroquinolones [Naladixic acid (30 μg), Ciprofloxacin (5 μg), Levofloxacin (5μg)], penicillin (Ampicillin 10 μg),Tetracycline (tetracycline 30 μg), Sulphonamides (Sulphamethoxazol 30 μg, and Carbapenems [Meropenem 10 μg, Imipenem 10 μg] were used. E. coli strain ATCC25922 was used as a control strain in the experiment. Highest resistance was observed against erythromycin (100%) followed by cefepime (97.4%) and clindamycin (82.1%), Nalidixic acid (61.5%), sulphamethazon (48.7%), tetracycline (41.0), kanamycin (33.3%), and cefotaxime (33.3%). Carapenems were found to be the most effective antimicrobial group where the examined STEC isolates were susceptible to Imipinem at 97.4% (38/39), followed by Meropenem at 94.9% (37/39). Results showed that multidrug resistance STEC isolates were 81.25% of the tested antimicrobial (13/16). In conclusion, high prevalence of STEC in raw milk indicate insufficient hygienic measures adopted during milking and handling and verify that raw milk is potential source of these multidrug resistant strains.
Keywords	amikacin ; ampicillin ; antibiotic resistance ; cattle ; cefazolin ; cefotaxime ; ciprofloxacin ; clindamycin ; cross-sectional studies ; erythromycin ; gentamicin ; hygiene ; imipenem ; levofloxacin ; meropenem ; milk ; multiple drug resistance ; nalidixic acid ; raw milk ; tetracycline ; Egypt
Language	English
Dates of publication	2022-03
Size	p. 31-46.
Publishing place	South Valley University
Document type	Article
ZDB-ID	2941832-X
ISSN	2535-1877 ; 2535-1826
ISSN (online)	2535-1877
ISSN	2535-1826
DOI	10.21608/SVU.2022.105577.1163
Database	NAL-Catalogue (AGRICOLA)

Order via subito

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito