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  1. Article ; Online: Ambivalent sexism within medicine: reflections from four medical students.

    Avini, Elhaam / Omran, Qabass / Mohamed, Fatemazahra / Ahmed, Zara

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2020  Volume 71, Issue 702, Page(s) 28–29

    MeSH term(s) Affect ; Attitude ; Humans ; Sexism ; Students, Medical
    Language English
    Publishing date 2020-12-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp21X714497
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 576: Show issues Location:
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  2. Article ; Online: Estimates of the Potential Impact of the COVID-19 Pandemic on Sexual and Reproductive Health In Low- and Middle-Income Countries.

    Riley, Taylor / Sully, Elizabeth / Ahmed, Zara / Biddlecom, Ann

    International perspectives on sexual and reproductive health

    2020  Volume 46, Page(s) 73–76

    Abstract: The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the disease a global pandemic on March 11, 2020. Governments around the world have had to ... ...

    Abstract The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the disease a global pandemic on March 11, 2020. Governments around the world have had to quickly adapt and respond to curb transmission of the virus and to provide care for the many who have been infected. The strain that the outbreak imposes on health systems will undoubtedly impact the sexual and reproductive health of individuals living in low- and middle-income countries (LMICs); however, sexual and reproductive health will also be affected by societal responses to the pandemic, such as local or national lockdowns that force health services to shut down if they are not deemed essential, as well as the consequences of physical distancing, travel restrictions and economic slowdowns.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Epidemics ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Reproduction ; SARS-CoV-2 ; Sexual Behavior ; Social Class
    Keywords covid19
    Language English
    Publishing date 2020-04-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2512464-X
    ISSN 1944-0405 ; 1944-0391
    ISSN (online) 1944-0405
    ISSN 1944-0391
    DOI 10.1363/46e9020
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  3. Article ; Online: Response to: history-taking in general practice: guidance for medical students.

    Omran, Qabass / Avini, Elhaam / Ahmed, Zara / Mohamed, Fatemazahra

    Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors

    2020  Volume 31, Issue 6, Page(s) 386

    MeSH term(s) Education, Medical, Undergraduate ; Family Practice ; General Practice ; Humans ; Students, Medical
    Language English
    Publishing date 2020-05-18
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2074818-8
    ISSN 1475-990X ; 1473-9879
    ISSN (online) 1475-990X
    ISSN 1473-9879
    DOI 10.1080/14739879.2020.1767514
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3195: Show issues Location:
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  4. Article ; Online: Corrigendum: Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy.

    Shafqat, Areez / Omer, Mohamed H / Ahmed, Eman Nayaz / Mushtaq, Ali / Ijaz, Eman / Ahmed, Zara / Alkattan, Khaled / Yaqinuddin, Ahmed

    Frontiers in immunology

    2023  Volume 14, Page(s) 1252998

    Abstract: This corrects the article DOI: 10.3389/fimmu.2023.1200941.]. ...

    Abstract [This corrects the article DOI: 10.3389/fimmu.2023.1200941.].
    Language English
    Publishing date 2023-07-13
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1252998
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  5. Article ; Online: Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy.

    Shafqat, Areez / Omer, Mohamed H / Ahmed, Eman Nayaz / Mushtaq, Ali / Ijaz, Eman / Ahmed, Zara / Alkattan, Khaled / Yaqinuddin, Ahmed

    Frontiers in immunology

    2023  Volume 14, Page(s) 1200941

    Abstract: This review focuses on the immunosuppressive effects of tumor angiogenesis and coagulation on the tumor microenvironment (TME). We summarize previous research efforts leveraging these observations and targeting these processes to enhance immunotherapy ... ...

    Abstract This review focuses on the immunosuppressive effects of tumor angiogenesis and coagulation on the tumor microenvironment (TME). We summarize previous research efforts leveraging these observations and targeting these processes to enhance immunotherapy outcomes. Clinical trials have documented improved outcomes when combining anti-angiogenic agents and immunotherapy. However, their overall survival benefit over conventional therapy remains limited and certain tumors exhibit poor response to anti-angiogenic therapy. Additionally, whilst preclinical studies have shown several components of the tumor coagulome to curb effective anti-tumor immune responses, the clinical studies reporting combinations of anticoagulants with immunotherapies have demonstrated variable treatment outcomes. By reviewing the current state of the literature on this topic, we address the key questions and future directions in the field, the answers of which are crucial for developing effective strategies to reprogram the TME in order to further the field of cancer immunotherapy.
    MeSH term(s) Humans ; Immunotherapy ; Neoplasms/therapy ; Immunomodulation ; Neovascularization, Pathologic/therapy ; Thrombosis ; Tumor Microenvironment
    Language English
    Publishing date 2023-07-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1200941
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  6. Article: lep Expression and Its Role in Obesity and Type-2 Diabetes.

    Qadir, Muhammad Imran / Ahmed, Zara

    Critical reviews in eukaryotic gene expression

    2017  Volume 27, Issue 1, Page(s) 47–51

    Abstract: Obesity is metabolic disorder that increases the risk of diabetes, heart disease, and other metabolic syndromes in human beings. One sign of diabetes is increased blood glucose levels in the body. Glucose levels increase due to problems with insulin ... ...

    Abstract Obesity is metabolic disorder that increases the risk of diabetes, heart disease, and other metabolic syndromes in human beings. One sign of diabetes is increased blood glucose levels in the body. Glucose levels increase due to problems with insulin secretion or insulin resistance. Maturity onset of diabetes of the young is more common in adults and occurs due to insulin resistance. Both diabetes and obesity are major problems that are responsible for the death of millions of individuals every year, worldwide. Leptin, a 164-KDa hormone that is secreted by white adipose tissue, is a product of the lep gene. Mutation in lep decreases leptin concentration and increases obesity and type-2 diabetes mellitus. Leptin has been shown to produce positive effects on hunger, energy expenditure, and behavior and is thus useful in the treatment of obesity and type-2 diabetes. Leptin controls appetite through its effect on the hypothalamus in the brain. Both leptin and insulin regulate appetite, body weight, and glucose levels in the body.
    MeSH term(s) Diabetes Mellitus, Type 2/metabolism ; Humans ; Insulin Resistance ; Leptin/physiology ; Obesity/metabolism
    Chemical Substances Leptin
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1071345-1
    ISSN 1045-4403
    ISSN 1045-4403
    DOI 10.1615/CritRevEukaryotGeneExpr.2017019386
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3226: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Estimates of the Potential Impact of the COVID-19 Pandemic on Sexual and Reproductive Health In Low- and Middle-Income Countries

    Riley, Taylor / Sully, Elizabeth / Ahmed, Zara / Biddlecom, Ann

    Int Perspect Sex Reprod Health

    Abstract: The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the disease a global pandemic on March 11, 2020. Governments around the world have had to ... ...

    Abstract The novel coronavirus (SARS-CoV-2) that causes COVID-19 has spread rapidly since emerging in late 2019, leading the World Health Organization (WHO) to declare the disease a global pandemic on March 11, 2020. Governments around the world have had to quickly adapt and respond to curb transmission of the virus and to provide care for the many who have been infected. The strain that the outbreak imposes on health systems will undoubtedly impact the sexual and reproductive health of individuals living in low- and middle-income countries (LMICs); however, sexual and reproductive health will also be affected by societal responses to the pandemic, such as local or national lockdowns that force health services to shut down if they are not deemed essential, as well as the consequences of physical distancing, travel restrictions and economic slowdowns.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32343244
    Database COVID19

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  8. Article: Emerging Biosensing Methods to Monitor Lung Cancer Biomarkers in Biological Samples: A Comprehensive Review.

    Chinnappan, Raja / Mir, Tanveer Ahmad / Alsalameh, Sulaiman / Makhzoum, Tariq / Alzhrani, Alaa / Alnajjar, Khalid / Adeeb, Salma / Al Eman, Noor / Ahmed, Zara / Shakir, Ismail / Al-Kattan, Khaled / Yaqinuddin, Ahmed

    Cancers

    2023  Volume 15, Issue 13

    Abstract: Lung cancer is the most commonly diagnosed of all cancers and one of the leading causes of cancer deaths among men and women worldwide, causing 1.5 million deaths every year. Despite developments in cancer treatment technologies and new pharmaceutical ... ...

    Abstract Lung cancer is the most commonly diagnosed of all cancers and one of the leading causes of cancer deaths among men and women worldwide, causing 1.5 million deaths every year. Despite developments in cancer treatment technologies and new pharmaceutical products, high mortality and morbidity remain major challenges for researchers. More than 75% of lung cancer patients are diagnosed in advanced stages, leading to poor prognosis. Lung cancer is a multistep process associated with genetic and epigenetic abnormalities. Rapid, accurate, precise, and reliable detection of lung cancer biomarkers in biological fluids is essential for risk assessment for a given individual and mortality reduction. Traditional diagnostic tools are not sensitive enough to detect and diagnose lung cancer in the early stages. Therefore, the development of novel bioanalytical methods for early-stage screening and diagnosis is extremely important. Recently, biosensors have gained tremendous attention as an alternative to conventional methods because of their robustness, high sensitivity, inexpensiveness, and easy handling and deployment in point-of-care testing. This review provides an overview of the conventional methods currently used for lung cancer screening, classification, diagnosis, and prognosis, providing updates on research and developments in biosensor technology for the detection of lung cancer biomarkers in biological samples. Finally, it comments on recent advances and potential future challenges in the field of biosensors in the context of lung cancer diagnosis and point-of-care applications.
    Language English
    Publishing date 2023-06-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15133414
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  9. Article ; Online: Building digital escape rooms for learning: From theory to practice.

    Pornsakulpaisal, Romket / Ahmed, Zara / Bok, Harold / de Carvalho Filho, Marco Antonio / Goka, Smruthik / Li, Lauren / Patki, Aditya / Salari, Shaudee / Sooknarine, Vitallia / Yap, Sook Woon / Moffett, Jenny

    The clinical teacher

    2023  Volume 20, Issue 2, Page(s) e13559

    Abstract: Digital games are increasingly used to support learning across a diverse range of cognitive, affective and psychomotor domains in health professions education. Game-based learning will likely become an important competency for educators. However, ... ...

    Abstract Digital games are increasingly used to support learning across a diverse range of cognitive, affective and psychomotor domains in health professions education. Game-based learning will likely become an important competency for educators. However, educators can perceive game building as out of their reach due to a lack of expertise in digital technology. This toolbox offers advice to health professions educators who would like to build a simple game for learning known as a digital educational escape room.
    MeSH term(s) Humans ; Learning ; Video Games
    Language English
    Publishing date 2023-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151518-9
    ISSN 1743-498X ; 1743-4971
    ISSN (online) 1743-498X
    ISSN 1743-4971
    DOI 10.1111/tct.13559
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  10. Article ; Online: Jellyfish Collagen: A Biocompatible Collagen Source for 3D Scaffold Fabrication and Enhanced Chondrogenicity.

    Ahmed, Zara / Powell, Lydia C / Matin, Navid / Mearns-Spragg, Andrew / Thornton, Catherine A / Khan, Ilyas M / Francis, Lewis W

    Marine drugs

    2021  Volume 19, Issue 8

    Abstract: Osteoarthritis (OA) is a multifactorial disease leading to degeneration of articular cartilage, causing morbidity in approximately 8.5 million of the UK population. As the dense extracellular matrix of articular cartilage is primarily composed of ... ...

    Abstract Osteoarthritis (OA) is a multifactorial disease leading to degeneration of articular cartilage, causing morbidity in approximately 8.5 million of the UK population. As the dense extracellular matrix of articular cartilage is primarily composed of collagen, cartilage repair strategies have exploited the biocompatibility and mechanical strength of bovine and porcine collagen to produce robust scaffolds for procedures such as matrix-induced chondrocyte implantation (MACI). However, mammalian sourced collagens pose safety risks such as bovine spongiform encephalopathy, transmissible spongiform encephalopathy and possible transmission of viral vectors. This study characterised a non-mammalian jellyfish (
    MeSH term(s) Animals ; Aquatic Organisms/chemistry ; Biocompatible Materials/chemistry ; Chondrogenesis/drug effects ; Collagen/chemistry ; Collagen/pharmacology ; Humans ; Osteoarthritis/therapy ; Scyphozoa ; Tissue Engineering ; Tissue Scaffolds/chemistry
    Chemical Substances Biocompatible Materials ; Collagen (9007-34-5)
    Language English
    Publishing date 2021-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md19080405
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