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Article ; Online: Correlation of Serum levels of Chromium, Copper, and Manganese with the Glucose levels in Type 2 Diabetes Mellitus in Iraq

Ahmed zaid / Hedef Dhafer Al-Yassin

مجلة كلية الطب, Vol 65, Iss

2024 Volume 4

Abstract: Correlation of Serum levels of Chromium, Copper, and Manganese with the Glucose levels in Type 2 Diabetes Mellitus in Ira Background: The metabolism of many trace elements such as chromium, copper, and manganese were reported to be altered in type 2 ... ...

Abstract	Correlation of Serum levels of Chromium, Copper, and Manganese with the Glucose levels in Type 2 Diabetes Mellitus in Ira Background: The metabolism of many trace elements such as chromium, copper, and manganese were reported to be altered in type 2 diabetes militates. This element may have specific roles in the pathogenesis and progress of this disease. Objectives: To evaluate the serum levels of copper, chromium, and manganese in type 2 diabetic patients in Iraq. Patients and Methods: This case-control study included 100 type 2 diabetic patients, 35-60 years old, with high BMI as cases, and 100 non-diabetic subjects as controls who were healthy volunteers not suffering from type 2 diabetes (staff and student). The data was collected from October 2022 until January 2023. The cases were seen in the Diabetes Consultation Unit / Baghdad Teaching Hospital / Medical City. Serum chromium, copper, and manganese were measured using atomic absorption. ELISA was used to test for insulin. spectrophotometry to measure glucose and HPLC was used to measure whole-blood HbA1c. Insulin resistance was calculated using the semi-empirical formula: HOMA-IR = glucose * insulin / 405 (glucose in mg/dl). To test for the difference between means of numerical data across several parameters, ANOVA tests were utilized. Pearson’s. correlation was used to test the correlation between variables. Results: Diabetics had higher HbA1c, serum copper (P value<0.01), and blood glucose than healthy controls. Compared to controls, diabetics had lower serum chromium (P value<0.01) and manganese (P value < 0.01). In diabetics, chromium and manganese are highly negatively correlated with insulin resistance. Copper levels increase with increasing insulin resistance. Insulin levels were greater in type 2 diabetics (18.6 ± 4.1mlU/L) than in the control (6.2 ± 1.3) (p <0.01). Conclusions: Serum copper was high while serum chromium and manganese were low in type 2 diabetics. that indicates that these elements may have a role in the occurrence and ...
Keywords	insulin resistance ; copper ; chromium ; insulin ; diabetes ; manganese ; glucose ; HbA1c ; Type 2 diabetes mellitus ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	571
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	College of Medicine University of Baghdad
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial.

Abdulah, Deldar Morad / Sulaiman, Saad Jbraeil / Ahmed, Zaid Waad

Clinical and experimental pediatrics

2024 Volume 67, Issue 4, Page(s) 203–212

Abstract: Background: Findings are conflicting regarding the effect of zinc supplementation on disease severity in children with acute gastroenteritis.: Purpose: To examine the effects of probiotics and zinc on the clinical outcomes of infants and children ... ...

Abstract	Background: Findings are conflicting regarding the effect of zinc supplementation on disease severity in children with acute gastroenteritis. Purpose: To examine the effects of probiotics and zinc on the clinical outcomes of infants and children with acute infectious diarrhea. Methods: In this randomized controlled trial, children with mild or moderate to severe acute gastroenteritis in the Kurdistan Region from November 2021 to June 2022 were diagnosed clinically and randomly assigned to the experimental or control group. The experimental group (n=50) received probiotics and zinc, whereas the control group (n=51) received probiotics alone for 1 week. The product contained live Bifidobacterium infantis, Lactobacillus paracasei, and Lactobacillus rhamnosus (10×106 colony-forming units/day for 7 days). Zinc syrup was administered to the probiotic plus zinc group. Each 5 mL of syrup contained 15 mg of zinc sulfate. Dehydration and disease severity in both groups were measured using the Clinical Dehydration Scale and the Modified Vesikari Scale, respectively. An illness episode was defined as an episode of gastroenteritis with a total score of ≥9 on the Modified Vesikari Scale (range, 0-20). Results: The probiotic and probiotic plus zinc groups were similar in age (1.79 years vs. 1.69 years, respectively; P= 0.645), sex (male/female ratio: 1.43 and 1.0, respectively; P=0.373), and medical characteristics. The groups had similar mean dehydration and disease severity scores and a similar incidence of dehydration recovery (some dehydration, 3.92% and 4.00%, respectively; P=1.000), and recovery from mild gastroenteritis (0.0% and 2.0%, respectively; P=0.495) at 2 weeks. Significant decreases in mean dehydration severity and disease severity score (1.80 to 0 and 6.66 to 0, respectively; P<0.001) and the development of dehydration (some dehydration, from 94.0% to 4.0%; P<0.001) from baseline to 2 weeks were noted in the probiotics plus zinc group. The probiotics group responded similarly. The development of mild gastroenteritis was significantly reduced from baseline to 2 weeks (90.2% to 0% and 78.0% to 2.0% in the probiotics and probiotics plus zinc groups, respectively; P<0.0001). The probiotics plus zinc group had a shorter mean recovery time (1.34 days vs. 2.00 days, respectively; P<0.001). Conclusion: Taking probiotics plus zinc did not significantly affect disease severity in children with gastroenteritis at 2 weeks. However, the probiotics plus zinc group recovered more quickly than the probiotics group.
Language	English
Publishing date	2024-02-19
Publishing country	Korea (South)
Document type	Journal Article
ISSN	2713-4148
ISSN (online)	2713-4148
DOI	10.3345/cep.2023.01340
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Algerian Energy Policy: Perspectives, Barriers, and Missed Opportunities.

Haddoum, Saliha / Bennour, Hocine / Ahmed Zaïd, Toudert

Global challenges (Hoboken, NJ)

2018 Volume 2, Issue 8, Page(s) 1700134

Abstract: Despite the uncertainties of the energy market impacted by the collapse of oil prices and a sharp increase in domestic energy consumption, Algeria continues to make huge efforts to bring energy access to its people. At the same time, the country is also ... ...

Abstract	Despite the uncertainties of the energy market impacted by the collapse of oil prices and a sharp increase in domestic energy consumption, Algeria continues to make huge efforts to bring energy access to its people. At the same time, the country is also witnessing a very slow start of the energy transition, which brings into question the energy-intensive development model accused of contributing both to global warming and to the depletion of fossil resources in the medium and long term. Although quantified targets are set, the National Program for the Development of Renewable Energies (NPDRE) struggles to take off and is lagging behind. There is no doubt that the recent fall in oil prices will further complicate the achievement of this transition; still one may raise the question of whether other barriers to the NPDRE should not be removed. Admittedly, the Algerian State has set up an incentive mechanism based on feed-in-tariffs to boost the NPDRE, but this failed to attract potential investors. This paper seeks to analyze the reasons for these failures as well as other issues linked with the energy-water-food trilemma. There are plenty, but the heavily subsidized energy products appear to be the most disabling.
Language	English
Publishing date	2018-07-03
Publishing country	Germany
Document type	Journal Article ; Review
ISSN	2056-6646
ISSN (online)	2056-6646
DOI	10.1002/gch2.201700134
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Article ; Online: Diagnosis of Hodgkin’s Lymphoma Using Endobronchial Ultrasound-Guided Transbronchial Needle

Abdullah Fahad Almsareer / Ahmed Zaid Alkhathlan / Doaa Ali AlGhamdi / Khalid Alokla

Case Reports in Medicine, Vol

2021 Volume 2021

Abstract: Endobronchial ultrasound-guided transbronchial biopsy has emerged as an excellent tool in diagnosing lung cancer. However, its use to diagnose lymphoma has been questioned, since the gold standard for diagnosing lymphomas is an excisional biopsy of ... ...

Abstract	Endobronchial ultrasound-guided transbronchial biopsy has emerged as an excellent tool in diagnosing lung cancer. However, its use to diagnose lymphoma has been questioned, since the gold standard for diagnosing lymphomas is an excisional biopsy of involved lymph nodes. However, the procedure is sometimes risky or difficult. Recent studies have been showing great results using endobronchial ultrasound-guided transbronchial needle aspiration when accompanied by immunohistochemistry and cytology. Here, we present a case of Hodgkin’s lymphoma patient that was accurately diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration.
Keywords	Medicine ; R
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Gouvernances publiques et entreprises publiques dans les économies de rente

Ahmed Zaid-Chertouk, Malika / Bance, Philippe

Annals of public and cooperative economics Vol. 86, No. 4 , p. 657-681

2015 Volume 86, Issue 4, Page(s) 657–681

Author's details	by Malika Ahmed Zaid-Chertouk et Philippe Bance
Keywords	Öffentliches Unternehmen ; Nachhaltige Entwicklung ; Rohstoffreichtum ; Rententheorie
Language	French
Publisher	Wiley-Blackwell
Publishing place	Oxford [u.a.]
Document type	Article
Note	Zsfassung in engl. Sprache
ZDB-ID	1240461-5 ; 2264947-5
ISSN	0770-8548
ISSN	0770-8548
Database	ECONomics Information System

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Article: Hemosuccus Pancreaticus in Chronic Pancreatitis: An Uncommon Cause of Gastrointestinal Bleeding.

Lee, William / Qi-Huang, Sunny / Ahmed, Zaid / Shah, Salman S

Journal of clinical imaging science

2020 Volume 10, Page(s) 72

Abstract: We present a case of a 69-year-old female who arrived in hemorrhagic shock with symptoms of upper gastrointestinal bleeding. Imaging on admission was diagnostic of a large splenic artery pseudoaneurysm, which was presumed to have bled into the pancreatic ...

Abstract	We present a case of a 69-year-old female who arrived in hemorrhagic shock with symptoms of upper gastrointestinal bleeding. Imaging on admission was diagnostic of a large splenic artery pseudoaneurysm, which was presumed to have bled into the pancreatic duct given clinical symptoms of upper gastrointestinal bleeding. The pseudoaneurysm was successfully treated with coil embolization resulting in resolution of clinical symptoms.
Language	English
Publishing date	2020-11-11
Publishing country	United States
Document type	Case Reports
ZDB-ID	2601233-9
ISSN	2156-5597 ; 2156-7514
ISSN (online)	2156-5597
ISSN	2156-7514
DOI	10.25259/JCIS_169_2020
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Diagnosis of Hodgkin's Lymphoma Using Endobronchial Ultrasound-Guided Transbronchial Needle.

Almsareer, Abdullah Fahad / Alkhathlan, Ahmed Zaid / AlGhamdi, Doaa Ali / Alokla, Khalid

Case reports in medicine

2021 Volume 2021, Page(s) 8910843

Abstract	Endobronchial ultrasound-guided transbronchial biopsy has emerged as an excellent tool in diagnosing lung cancer. However, its use to diagnose lymphoma has been questioned, since the gold standard for diagnosing lymphomas is an excisional biopsy of involved lymph nodes. However, the procedure is sometimes risky or difficult. Recent studies have been showing great results using endobronchial ultrasound-guided transbronchial needle aspiration when accompanied by immunohistochemistry and cytology. Here, we present a case of Hodgkin's lymphoma patient that was accurately diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration.
Language	English
Publishing date	2021-02-27
Publishing country	United States
Document type	Case Reports
ZDB-ID	2502642-2
ISSN	1687-9635 ; 1687-9627
ISSN (online)	1687-9635
ISSN	1687-9627
DOI	10.1155/2021/8910843
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Article ; Online: Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes.

Froidevaux-Klipfel, Laurence / Targa, Benjamin / Cantaloube, Isabelle / Ahmed-Zaïd, Hayat / Poüs, Christian / Baillet, Anita

Oncotarget

2015 Volume 6, Issue 34, Page(s) 36063–36080

Abstract: The mechanisms of cancer cell adaptation to the anti-microtubule agents of the taxane family are multifaceted and still poorly understood. Here, in a model of breast cancer cells which display amplified microtubule dynamics to resist Taxol®, we provide ... ...

Abstract	The mechanisms of cancer cell adaptation to the anti-microtubule agents of the taxane family are multifaceted and still poorly understood. Here, in a model of breast cancer cells which display amplified microtubule dynamics to resist Taxol®, we provide evidence that septin filaments containing high levels of SEPT9_i1 bind to microtubules in a way that requires tubulin long chain polyglutamylation. Reciprocally, septin filaments provide a scaffold for elongating and trimming polyglutamylation enzymes to finely tune the glutamate side-chain length on microtubules to an optimal level. We also demonstrate that tubulin retyrosination and/or a high level of tyrosinated tubulin is crucial to allow the interplay between septins and polyglutamylation on microtubules and that together, these modifications result in an enhanced CLIP-170 and MCAK recruitment to microtubules. Finally, the inhibition of tubulin retyrosination, septins, tubulin long chain polyglutamylation or of both CLIP-170 and MCAK allows the restoration of cell sensitivity to taxanes, providing evidence for a new integrated mechanism of resistance.
MeSH term(s)	Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Humans ; Microtubules/drug effects ; Microtubules/metabolism ; Paclitaxel/pharmacology ; Polyglutamic Acid/metabolism ; Septins/metabolism ; Tubulin/metabolism
Chemical Substances	Tubulin ; Polyglutamic Acid (25513-46-6) ; Septins (EC 3.6.1.-) ; Paclitaxel (P88XT4IS4D)
Language	English
Publishing date	2015-11-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2560162-3
ISSN	1949-2553 ; 1949-2553
ISSN (online)	1949-2553
ISSN	1949-2553
DOI	10.18632/oncotarget.5373
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Article ; Online: The interventions and outcomes associated with fall-related injuries at tertiary hospitals in the Kingdom of Saudi Arabia

Sameer Al-Ghamdi / Ahmed Mohammed Alosaimi / Abdullah Omar Bin Shihah / Abdulrahman Ibrahim Alhadlaq / Musaad Abdullah Alotaibi / Ahmed Zaid Alnefaie / Faisal Musaad Alsaleh / Saad Fahad Alotaibi / Saud Fahad Alotaibi

The Pan African Medical Journal, Vol 36, Iss

a cross sectional study

2020 Volume 314

Abstract: INTRODUCTION: fall-related injuries are an important health concern around the globe, imposing an immense economic burden. The aim of this study is to evaluate the interventions and outcomes associated with fall-related injuries in a tertiary hospital in ...

Abstract	INTRODUCTION: fall-related injuries are an important health concern around the globe, imposing an immense economic burden. The aim of this study is to evaluate the interventions and outcomes associated with fall-related injuries in a tertiary hospital in the Kingdom of Saudi Arabia (KSA). METHODS: a cross-sectional study including 264 patients with fall-related injuries was conducted at the King Khalid Hospital and Prince Sultan Centre for Health Care and other hospitals in Al Kharj from March 01, 2019 to November 30, 2019. The patients were recruited, identified at the point of presentation to the emergency department and followed through the triage, admission and discharge processes. The researchers analysed the participant’s clinical notes on the electronic health record (EHR) to obtain information relevant to the study, including demographic information, the injury patterns and their management. RESULTS: most patients studied were children under the age of 10 (25.7%). The vast majority (96.9%) of patients fell from a height, while the rest fell from a height onto a sharp object. Most of them (90.9%) had experienced no shock symptoms. Upper limb injuries had the highest prevalence (37.8%), followed by lower limb injuries (22.7%), head injuries (19.7%) and skull fractures (13.6%). Invasive surgery, blood transfusions, admission to intensive care (ICU) and thoracostomy (chest tube) were required by 74%, 3%, 3% and 2% of patients, respectively. CONCLUSION: fall-related injuries may result in invasive surgery, chest drain insertion, or ICU admission, increasing the burden on the healthcare system.
Keywords	accidental falls ; wounds and injuries ; case management ; saudi arabia ; Medicine ; R
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	The Pan African Medical Journal
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The interventions and outcomes associated with fall-related injuries at tertiary hospitals in the Kingdom of Saudi Arabia: a cross sectional study.

Al-Ghamdi, Sameer / Alosaimi, Ahmed Mohammed / Shihah, Abdullah Omar Bin / Alhadlaq, Abdulrahman Ibrahim / Alotaibi, Musaad Abdullah / Alnefaie, Ahmed Zaid / Alsaleh, Faisal Musaad / Alotaibi, Saad Fahad / Alotaibi, Saud Fahad

The Pan African medical journal

2020 Volume 36, Page(s) 314

Abstract: Introduction: fall-related injuries are an important health concern around the globe, imposing an immense economic burden. The aim of this study is to evaluate the interventions and outcomes associated with fall-related injuries in a tertiary hospital ... ...

Abstract	Introduction: fall-related injuries are an important health concern around the globe, imposing an immense economic burden. The aim of this study is to evaluate the interventions and outcomes associated with fall-related injuries in a tertiary hospital in the Kingdom of Saudi Arabia (KSA). Methods: a cross-sectional study including 264 patients with fall-related injuries was conducted at the King Khalid Hospital and Prince Sultan Centre for Health Care and other hospitals in Al Kharj from March 01, 2019 to November 30, 2019. The patients were recruited, identified at the point of presentation to the emergency department and followed through the triage, admission and discharge processes. The researchers analysed the participant´s clinical notes on the electronic health record (EHR) to obtain information relevant to the study, including demographic information, the injury patterns and their management. Results: most patients studied were children under the age of 10 (25.7%). The vast majority (96.9%) of patients fell from a height, while the rest fell from a height onto a sharp object. Most of them (90.9%) had experienced no shock symptoms. Upper limb injuries had the highest prevalence (37.8%), followed by lower limb injuries (22.7%), head injuries (19.7%) and skull fractures (13.6%). Invasive surgery, blood transfusions, admission to intensive care (ICU) and thoracostomy (chest tube) were required by 74%, 3%, 3% and 2% of patients, respectively. Conclusion: fall-related injuries may result in invasive surgery, chest drain insertion, or ICU admission, increasing the burden on the healthcare system.
MeSH term(s)	Accidental Falls/statistics & numerical data ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Saudi Arabia/epidemiology ; Tertiary Care Centers ; Treatment Outcome ; Wounds and Injuries/epidemiology ; Wounds and Injuries/etiology ; Wounds and Injuries/therapy ; Young Adult
Language	English
Publishing date	2020-08-20
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2020.36.314.21943
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