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  1. Article ; Online: Relation between orthorexia nervosa and healthy orthorexia: A latent profile analysis.

    Boutin, Camille / Maïano, Christophe / Aimé, Annie

    Appetite

    2023  Volume 194, Page(s) 107165

    Abstract: Orthorexic eating behaviors can be conceptualized as a bidimensional construct encompassing an orthorexia nervosa dimension (ON) and a healthy orthorexia dimension (HO). Although variable-centered studies showed that ON and HO are distinguishable ... ...

    Abstract Orthorexic eating behaviors can be conceptualized as a bidimensional construct encompassing an orthorexia nervosa dimension (ON) and a healthy orthorexia dimension (HO). Although variable-centered studies showed that ON and HO are distinguishable orthorexic eating behaviors, the evidence of whether they can co-occur or be distinct in subgroups of individuals is still limited. The present study aimed to address previous person-centered studies' limitations by examining profiles of ON and HO among a convenience sample of 251 French-speaking Canadian adults (85.7% women; M
    MeSH term(s) Adult ; Humans ; Female ; Male ; Orthorexia Nervosa ; Canada ; Feeding and Eating Disorders ; Diet, Vegetarian ; Vegetarians ; Feeding Behavior ; Surveys and Questionnaires ; Health Behavior
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2023.107165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Profiles of body image concerns and their associations with disordered eating behaviors.

    Baker, Sarah / Maïano, Christophe / Houle, Simon A / Nadon, Lindsey / Aimé, Annie / Morin, Alexandre J S

    Appetite

    2023  Volume 191, Page(s) 107082

    Abstract: Although body image concerns (BIC) are recognized as a core driver in the development of disordered eating behaviors, the combined role of various types of BIC remains underexamined. This study relied on latent profile analysis to identify the main ... ...

    Abstract Although body image concerns (BIC) are recognized as a core driver in the development of disordered eating behaviors, the combined role of various types of BIC remains underexamined. This study relied on latent profile analysis to identify the main configurations of self-reported BIC (i.e., body checking and avoidance, perceived physical appearance, and fear of negative appearance evaluation) observed in a sample of 419 French-Canadian individuals (M
    Language English
    Publishing date 2023-10-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2023.107082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Validation of a Virtual Environment to Induce State Social Physique Anxiety in Women with Obesity and Social Physique Anxiety.

    Jeanningros, Alice / Baillot, Aurélie / Corno, Giulia / Rivard, Marie-Christine / Aimé, Annie / Bouchard, Stéphane

    Journal of clinical medicine

    2023  Volume 12, Issue 18

    Abstract: State Social Physique Anxiety (SPA), in contrast to Trait SPA, is triggered by specific situations that elicit SPA. To date, no research has used virtual reality (VR) to recreate a situation that may elicit State SPA. The purpose of this study is to ... ...

    Abstract State Social Physique Anxiety (SPA), in contrast to Trait SPA, is triggered by specific situations that elicit SPA. To date, no research has used virtual reality (VR) to recreate a situation that may elicit State SPA. The purpose of this study is to validate a virtual environment (VE) that simulates an anxiogenic situation to induce State SPA in women with obesity and high SPA. The high SPA group consisted of 25 self-identified women living with obesity and high Trait SPA. The low SPA group consisted of 20 self-identified women with low SPA. All participants were immersed in a virtual swimming pool environment for 10 min using a virtual reality headset. After the immersion, State SPA and fear of being negatively judged felt during immersion were measured with self-report questionnaires. A questionnaire assessing unwanted negative side effects was administered before and after the immersion. Using an ANCOVA with Trait SPA as covariate, State SPA was found to be significantly higher in the high SPA group. Fear of being judged negatively was also significantly higher in the high SPA group. Unwanted negative side effects scores did not increase post-immersion in either group. This study documents the validity of a novel VE for inducing State SPA in women with obesity and high SPA.
    Language English
    Publishing date 2023-09-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12186065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Body image interventions within breast cancer care: A systematic review and concept analysis.

    Anne Thamar Louis, Lunie / Fortin, Justine / Roy, Carol-Anne / Brunet, Alain / Aimé, Annie

    Journal of psychosocial oncology

    2023  Volume 42, Issue 3, Page(s) 427–447

    Abstract: There needs to be a consensus regarding the definition of body image in oncology the literature. This lack of agreement leads to conflicting results in psychosocial interventions aimed to improve body image among breast cancer patients. Through an ... ...

    Abstract There needs to be a consensus regarding the definition of body image in oncology the literature. This lack of agreement leads to conflicting results in psychosocial interventions aimed to improve body image among breast cancer patients. Through an instrumentalist approach, this systematic review aims to analyze how body image as a concept is described and operationalized in breast cancer studies with the focus to enhance body image through psychosocial interventions. Databases were searched in October 2022 and updated in February 2023 to find empirical studies reporting psychosocial intervention targeting body image efficacy. The results from 24 studies show many similarities and differences between the definitions (e.g. characteristics) and questionnaires (e.g. Cronbach's alpha coefficient) used to evaluate this concept. Most definitions include thoughts, feelings, and behaviors related to body image. Finally, the psychosocial implications are discussed. This systematic review is registered on the International Prospective Register of Systematic Reviews (PROSPERO; CRD42022326393).
    MeSH term(s) Humans ; Breast Neoplasms/psychology ; Breast Neoplasms/therapy ; Body Image/psychology ; Female ; Psychosocial Intervention
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article ; Systematic Review ; Review
    ZDB-ID 605892-9
    ISSN 1540-7586 ; 0734-7332
    ISSN (online) 1540-7586
    ISSN 0734-7332
    DOI 10.1080/07347332.2023.2249879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor.

    Aime A Levesque / Rebecca M Pappalardo / Pawan Puli / Laura A Enzor / Clara Angeles

    PLoS ONE, Vol 17, Iss 2, p e

    2022  Volume 0263463

    Abstract: Neuroblastomas are one of the most common types of solid tumors in infants and children and are responsible for approximately 15% of childhood cancer deaths. Neuroblastomas rarely have mutations in p53, with less than 2% of NB containing mutations in p53, ...

    Abstract Neuroblastomas are one of the most common types of solid tumors in infants and children and are responsible for approximately 15% of childhood cancer deaths. Neuroblastomas rarely have mutations in p53, with less than 2% of NB containing mutations in p53, compared to up to 60% for other tumor classes. Previous studies on the therapeutic combination of a DNA damaging agent and checkpoint kinase 1 (Chk1) inhibitor have shown that DNA damage-induced cell cycle arrest can be specifically abrogated in p53-defective tumors. However, some p53-wildtype tumors have also been shown to be sensitive to this therapeutic combination, suggesting that these cells have other defects in the p53 response that can be exploited for therapeutic purposes. In the current study, we investigated the response to the combination of a DNA damaging agent (SN38) and a Chk1 inhibitor (UCN-01) of four p53-wildtype neuroblastoma cell lines: SK-N-SH, SH-SY5Y, SK-N-AS, and Lan-5. When the cells were treated with concentrations of SN38 ranging from 0-30 ng/ml, all four cell lines accumulated p53 which was phosphorylated on serines 15 and 20. However, only the SK-N-SH were found to activate p21waf1 and repress cyclin B. In order to assess sensitivity to UCN-01-mediated abrogation of cell cycle arrest, cell were treated with 10 ng/ml SN38 for 24 h, followed by 25 nM UCN-01 for 6 and 24 h. The SK-N-SH showed no sensitivity to UCN-01 treatment whereas the SH-SY5Y, SK-N-AS, and Lan-5 abrogated G2 arrest within 24 h. Our recent studies revealed that cells that are sensitive to checkpoint abrogation lack p53 dimers and tetramers, so we analyzed the oligomerization status of p53 in all four cell lines using glutaraldehyde crosslinking. The SK-N-SH cells possessed levels of p53 dimers and tetramers similar to what has previously been reported in p53-wildtype MCF10A cells. The SH-SY5Y, SK-N-AS, and Lan-5 however, had extremely low to undetectable levels of dimers and tetramers. Our study also showed no cytoplasmic accumulation of p53 in these cells contrary ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Appendicular myxoglobulosis; a rare form of appendicular mucocele.

    Joly, M A / Aime, A / Souraud, J-B / Malgras, B

    Journal of visceral surgery

    2019  Volume 157, Issue 4, Page(s) 359–361

    Abstract: Myxoglobulosis is a particular, rare, form of appendicular mucocele, characterized by the presence of numerous, occasionally calcified, globules that are grouped together like grapes, and look like pearls or fish eggs, in the appendicular lumen. The ... ...

    Abstract Myxoglobulosis is a particular, rare, form of appendicular mucocele, characterized by the presence of numerous, occasionally calcified, globules that are grouped together like grapes, and look like pearls or fish eggs, in the appendicular lumen. The diagnosis of myxoglobulosis is most often fortuitous, but sometimes, can be made in the face of acute appendicitis or another setting of abdominal pain. Imaging (sonography or computerized tomography (CT)) is highly suggestive when it shows a cystic, encapsulated, oblong, well-delineated mass, containing (heterogeneous, liquid, and viscous) mucus with calcified globules. In contrast to acute appendicitis, the wall of the appendix is thin (<6mm) and there is no peri-appendicular inflammation. Long-term complications are similar to other appendicular mucoceles, including invagination, bleeding, perforation, peritonitis and peritoneal pseudomyxoma.
    MeSH term(s) Appendectomy/methods ; Appendix/diagnostic imaging ; Appendix/pathology ; Appendix/surgery ; Cecal Diseases/diagnosis ; Cecal Diseases/pathology ; Cecal Diseases/surgery ; Female ; Humans ; Laparoscopy ; Mucocele/diagnosis ; Mucocele/pathology ; Mucocele/surgery ; Tomography, X-Ray Computed ; Young Adult
    Language English
    Publishing date 2019-11-08
    Publishing country France
    Document type Case Reports ; Journal Article
    ISSN 1878-7886
    ISSN (online) 1878-7886
    DOI 10.1016/j.jviscsurg.2019.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Demokratisierung und Perspektiven der bäuerlichen Partizipation in Madagaskar

    Raveloson, Jean-Aimé A.

    2001  

    Author's details vorgelegt von Jean-Aimé A. Raveloson
    Language German
    Size 351, XXVII S.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bonn, Univ., Diss., 2000
    Note Zsfassung in engl. Sprache
    HBZ-ID HT012906061
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  8. Book ; Thesis: Demokratisierung und Perspektiven der bäuerlichen Partizipation in Madagaskar

    Raveloson, Jean-Aimé A.

    (Bonner Studien zur Wirtschaftssoziologie ; 16)

    2001  

    Author's details Jean-Aimé Raveloson
    Series title Bonner Studien zur Wirtschaftssoziologie ; 16
    Collection
    Keywords Madagaskar ; Demokratisierung ; Partizipation ; Bauer
    Subject Bauernschaft ; Bauernstand ; Bauerntum ; Bauern ; Gesellschaft
    Language German
    Size VII, 351, XXVII S. : Kt.
    Edition 1. Aufl.
    Publisher Wehle
    Publishing place Witterschlick/Bonn
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bonn, Univ., Diss., 2000
    Note Zsfassung in engl. Sprache
    Remark Abt. Nussallee/Bereichsbibl. ZBMed: Auch unter der Signatur 004/1091 vorhanden
    HBZ-ID HT013064170
    ISBN 3-935307-04-7 ; 978-3-935307-04-8
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  9. Article ; Online: p53 oligomerization status as an indicator of sensitivity of p53-wildtype neuroblastomas to the combination of DNA damaging agent and Chk1 inhibitor.

    Levesque, Aime A / Pappalardo, Rebecca M / Puli, Pawan / Enzor, Laura A / Angeles, Clara

    PloS one

    2022  Volume 17, Issue 2, Page(s) e0263463

    Abstract: Neuroblastomas are one of the most common types of solid tumors in infants and children and are responsible for approximately 15% of childhood cancer deaths. Neuroblastomas rarely have mutations in p53, with less than 2% of NB containing mutations in p53, ...

    Abstract Neuroblastomas are one of the most common types of solid tumors in infants and children and are responsible for approximately 15% of childhood cancer deaths. Neuroblastomas rarely have mutations in p53, with less than 2% of NB containing mutations in p53, compared to up to 60% for other tumor classes. Previous studies on the therapeutic combination of a DNA damaging agent and checkpoint kinase 1 (Chk1) inhibitor have shown that DNA damage-induced cell cycle arrest can be specifically abrogated in p53-defective tumors. However, some p53-wildtype tumors have also been shown to be sensitive to this therapeutic combination, suggesting that these cells have other defects in the p53 response that can be exploited for therapeutic purposes. In the current study, we investigated the response to the combination of a DNA damaging agent (SN38) and a Chk1 inhibitor (UCN-01) of four p53-wildtype neuroblastoma cell lines: SK-N-SH, SH-SY5Y, SK-N-AS, and Lan-5. When the cells were treated with concentrations of SN38 ranging from 0-30 ng/ml, all four cell lines accumulated p53 which was phosphorylated on serines 15 and 20. However, only the SK-N-SH were found to activate p21waf1 and repress cyclin B. In order to assess sensitivity to UCN-01-mediated abrogation of cell cycle arrest, cell were treated with 10 ng/ml SN38 for 24 h, followed by 25 nM UCN-01 for 6 and 24 h. The SK-N-SH showed no sensitivity to UCN-01 treatment whereas the SH-SY5Y, SK-N-AS, and Lan-5 abrogated G2 arrest within 24 h. Our recent studies revealed that cells that are sensitive to checkpoint abrogation lack p53 dimers and tetramers, so we analyzed the oligomerization status of p53 in all four cell lines using glutaraldehyde crosslinking. The SK-N-SH cells possessed levels of p53 dimers and tetramers similar to what has previously been reported in p53-wildtype MCF10A cells. The SH-SY5Y, SK-N-AS, and Lan-5 however, had extremely low to undetectable levels of dimers and tetramers. Our study also showed no cytoplasmic accumulation of p53 in these cells contrary to some previous reports. The results of this study suggest that oligomerization status may serve as an indicator of sensitivity of p53-wildtype tumors to the therapeutic combination of DNA damaging agent and Chk1 inhibitor.
    MeSH term(s) Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; DNA Damage ; DNA, Neoplasm/drug effects ; Genes, p53 ; Humans ; Irinotecan/pharmacology ; Irinotecan/therapeutic use ; Neuroblastoma/drug therapy ; Neuroblastoma/genetics ; Staurosporine/analogs & derivatives ; Staurosporine/pharmacology ; Staurosporine/therapeutic use ; Topoisomerase I Inhibitors/pharmacology ; Topoisomerase I Inhibitors/therapeutic use
    Chemical Substances Antineoplastic Agents ; DNA, Neoplasm ; Topoisomerase I Inhibitors ; Irinotecan (7673326042) ; 7-hydroxystaurosporine (7BU5H4V94A) ; Staurosporine (H88EPA0A3N)
    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0263463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Psychometric properties of the Teruel Orthorexia Scale (TOS) among a French-Canadian adult sample.

    Maïano, Christophe / Aimé, Annie / Almenara, Carlos A / Gagnon, Cynthia / Barrada, Juan Ramón

    Eating and weight disorders : EWD

    2022  

    Abstract: Background: Psychometric properties of the Teruel Orthorexia Scale (TOS) have been examined in several languages (Arabic, English, Portuguese, Spanish, and Turkish), but not in French.: Purpose: The objective was to examine the psychometric ... ...

    Abstract Background: Psychometric properties of the Teruel Orthorexia Scale (TOS) have been examined in several languages (Arabic, English, Portuguese, Spanish, and Turkish), but not in French.
    Purpose: The objective was to examine the psychometric properties of the TOS among a French-Canadian adult sample.
    Methods: Participants were 296 French-speaking Canadian adults (M = 34.2 years, SD = 11.9, 85.1% women). They completed the TOS alongside with several other measures (e.g., alcoholic consumption, cigarette smoking, disturbed eating attitudes and behaviors, frequency of physical activities, intuitive eating, vegetarian diet, and negative affect).
    Results: The results supported the a priori two-factor representation (orthorexia nervosa and healthy orthorexia) of the French version of the TOS and provided further support for the superiority of an exploratory structural equation modeling approach, relative to a confirmatory factor analytic approach. Furthermore, the results supported no differential item functioning as a function of respondents' characteristics (age, body mass index, diagnosis of eating disorders, frequency of physical activities, gender, and vegetarian diet). Latent mean differences were found in healthy orthorexia and orthorexia nervosa factors as a function of respondents' characteristics. Finally, significant correlations were found between TOS factors and convergent measures (alcohol consumption, cigarette smoking, disturbed eating attitudes and behaviors, intuitive eating, and negative affect).
    Conclusion: The present study confirmed that the French version of the TOS has satisfactory psychometric properties (i.e., factor validity and reliability, no differential item functioning, and convergent validity).
    Level of evidence: V, cross-sectional study.
    Language English
    Publishing date 2022-09-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-022-01482-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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