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  1. Article ; Online: Response to Dr Khursheed Jeejeebhoy.

    Sheean, Patricia M / Peterson, Sarah J / Perez, Sandra Gomez / Troy, Karen L / Patel, Ankur / Sclamberg, Joy S / Ajanaku, Folabomi C / Braunschweig, Carol A

    JPEN. Journal of parenteral and enteral nutrition

    2015  Volume 39, Issue 3, Page(s) 271–272

    MeSH term(s) Body Composition ; Female ; Humans ; Male ; Muscle, Skeletal ; Nutritional Status ; Respiratory Insufficiency/complications ; Sarcopenia/epidemiology
    Language English
    Publishing date 2015-02-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 800861-9
    ISSN 1941-2444 ; 0148-6071
    ISSN (online) 1941-2444
    ISSN 0148-6071
    DOI 10.1177/0148607114562889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The prevalence of sarcopenia in patients with respiratory failure classified as normally nourished using computed tomography and subjective global assessment.

    Sheean, Patricia M / Peterson, Sarah J / Gomez Perez, Sandra / Troy, Karen L / Patel, Ankur / Sclamberg, Joy S / Ajanaku, Folabomi C / Braunschweig, Carol A

    JPEN. Journal of parenteral and enteral nutrition

    2013  Volume 38, Issue 7, Page(s) 873–879

    Abstract: Background: Declines in nutrition status and adverse body composition changes frequently occur in the critically ill. The objective of this cross-sectional study was to examine the prevalence of sarcopenia and its occurrence in patients classified as ... ...

    Abstract Background: Declines in nutrition status and adverse body composition changes frequently occur in the critically ill. The objective of this cross-sectional study was to examine the prevalence of sarcopenia and its occurrence in patients classified as normal nourished using subjective global assessment (SGA).
    Methods: Exploiting diagnostic CT images, skeletal muscle mass at the L3 region was quantified and used to determine sarcopenia and its association with normal nutrition status in 56 patients with respiratory failure. Sarcopenia was defined as an L3 skeletal muscle index of ≤38.5 cm(2)/m(2) for women and ≤52.4 cm(2)/m(2) for men. CT imaging and SGA classifications completed within 14, 10 and 7 days of each other were analyzed to assess sarcopenia and the influence of time between scans on misclassification (ie, normal nourished and sarcopenic). Descriptive statistics were conducted.
    Results: The average patient was 59.2 (± 15.6) years old, admitted with sepsis/infection, an APACHE II score of 26 (± 8.0), and BMI of 28.3 (± 5.8). Sarcopenia and sarcopenic obesity were prevalent in a minimum of 56% and 24% of patients, respectively, depending on the number of days between CT imaging and SGA assessment. Misclassified individuals were predominantly male, minority and overweight or obese. Controlling for age, no significant differences were noted for patients classified as normal nourished vs malnourished by SGA for lumbar muscle cross-sectional, whole-body lean mass, or skeletal muscle index.
    Conclusions: Sarcopenia is highly prevalent among patients with respiratory failure requiring mechanical ventilation (MV) and not readily detected in patients classified as normal nourished using SGA.
    MeSH term(s) Adult ; Aged ; Body Composition ; Body Mass Index ; Critical Illness ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Minority Groups ; Muscle, Skeletal ; Nutrition Assessment ; Nutritional Status ; Obesity/complications ; Overweight ; Prevalence ; Reference Values ; Respiration, Artificial ; Respiratory Insufficiency/complications ; Sarcopenia/complications ; Sarcopenia/epidemiology ; Sepsis ; Sex Factors ; Tomography
    Language English
    Publishing date 2013-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 800861-9
    ISSN 1941-2444 ; 0148-6071
    ISSN (online) 1941-2444
    ISSN 0148-6071
    DOI 10.1177/0148607113500308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exploitation of diagnostic computed tomography scans to assess the impact of nutrition support on body composition changes in respiratory failure patients.

    Braunschweig, Carol A / Sheean, Patricia M / Peterson, Sarah J / Gomez Perez, Sandra / Freels, Sally / Troy, Karen L / Ajanaku, Folabomi C / Patel, Ankur / Sclamberg, Joy S / Wang, Zebin

    JPEN. Journal of parenteral and enteral nutrition

    2013  Volume 38, Issue 7, Page(s) 880–885

    Abstract: Background: Assessment of nutritional status in intensive care unit (ICU) patients is limited. Computed tomography (CT) scans that include the first to fifth lumbar region completed for diagnostic purposes measures fat and lean body mass (LBM) depots ... ...

    Abstract Background: Assessment of nutritional status in intensive care unit (ICU) patients is limited. Computed tomography (CT) scans that include the first to fifth lumbar region completed for diagnostic purposes measures fat and lean body mass (LBM) depots and are frequently done in ICU populations and can be used to quantify fat and LBM depots. The purpose of this study was to assess if these scans could measure change in skeletal muscle (SKT), visceral adipose (VAT), and intermuscular adipose (IMAT) tissue and to examine the association between the amount of energy and protein received and changes in these depots.
    Methods: Cross-sectional area of SKT, VAT, and IMAT from CT scans at the third lumbar region was quantified at 2 time points (CT1 and CT2). Change scores between CT1 and CT2 for each of these depots and the percentage of estimated energy/protein needs received were determined in 33 adults that with acute respiratory failure. Descriptive statistics and multiple regression was used to evaluate the influence of baseline characteristics and the percentage energy/protein needs received between CT1 and CT2 on percentage change/day between CT1 and CT2 on SKM, IMAT, and VAT.
    Results: Participants were on average (SD) 59.7 (16) years old, received 41% of energy and 57% of protein needs. The average time between CT1 and CT2 was 10 (5) days. SKM declined 0.49%/day (men P = .07, women P = .09) and percentage of energy needs received reduced loss (β = 0.024, P = .03). No change in VAT or IMAT occurred.
    Conclusions: CT scans can be exploited to assess change in body composition in ICU patients and may assist in detecting the causal link between nutritional support and outcomes in future clinical trials.
    MeSH term(s) Adipose Tissue ; Adult ; Aged ; Body Composition ; Body Fluid Compartments ; Critical Illness/therapy ; Dietary Proteins/administration & dosage ; Energy Intake ; Female ; Humans ; Intensive Care Units ; Intra-Abdominal Fat ; Lumbosacral Region ; Male ; Middle Aged ; Muscle, Skeletal ; Nutrition Assessment ; Nutritional Requirements ; Nutritional Status ; Nutritional Support ; Obesity/complications ; Respiratory Insufficiency/therapy ; Tomography/methods
    Chemical Substances Dietary Proteins
    Language English
    Publishing date 2013-08-23
    Publishing country United States
    Document type Evaluation Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 800861-9
    ISSN 1941-2444 ; 0148-6071
    ISSN (online) 1941-2444
    ISSN 0148-6071
    DOI 10.1177/0148607113500505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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