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  1. Article ; Online: Prevalence, risk factors and outcome of congenital anomalies among neonatal admissions in OGBOMOSO, Nigeria.

    Ajao, Akinlabi E / Adeoye, Ikeola A

    BMC pediatrics

    2019  Volume 19, Issue 1, Page(s) 88

    Abstract: Background: Congenital anomalies (CA) are a major cause of neonatal morbidity and mortality, especially in developing countries. Data on these anomalies are still poorly collated in developing countries. We aimed to assess the prevalence, pattern, risk ... ...

    Abstract Background: Congenital anomalies (CA) are a major cause of neonatal morbidity and mortality, especially in developing countries. Data on these anomalies are still poorly collated in developing countries. We aimed to assess the prevalence, pattern, risk factors and outcome of congenital anomalies among neonatal admissions in Ogbomoso Town, Nigeria.
    Methods: A cross-sectional retrospective study in which a review of the records of all neonates admitted in the neonatal unit of the Bowen University Teaching Hospital, Ogbomoso over a five-year period (January 2012-December 2016) was undertaken. The occurrence rate and pattern of anomalies were determined, while factors associated with the occurrence and outcome of anomalies were calculated with the odds ratio and 95% confidence interval. Data entry and analysis were performed using SPSS version 21.
    Results: CA were found in 67 of the 1057 neonatal admissions, giving a prevalence rate of 6.3%. Anomalies of the cardiovascular and digestive systems were the most common. A higher proportion of babies referred from other facilities had CA, and this was found statistically significant. There was no significant association between CA and low birth weight, sex, maternal age or parity. The mortality rate among neonates with CA was 10.4%. Although, CA was associated with reduced risk of neonatal mortality compared to those with other acute conditions, this was not statistically significantly.
    Conclusion: CA is a major indication for neonatal admissions in Ogbomoso. There is the need to establish a surveillance system for CA and efforts should be made to raise awareness of the occurrence and risk factors of CA in developing countries.
    MeSH term(s) Cause of Death ; Congenital Abnormalities/epidemiology ; Congenital Abnormalities/mortality ; Cross-Sectional Studies ; Hospitalization ; Hospitals, University ; Humans ; Infant ; Infant Mortality ; Infant, Newborn ; Infant, Newborn, Diseases/epidemiology ; Nigeria/epidemiology ; Prevalence ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2019-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-019-1471-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Congenital infantile digital fibromatosis: a case report and review of the literature.

    Adegoke, Omolade O / Ajao, Akinlabi E / Ano-Edward, Gbemi H

    African health sciences

    2020  Volume 20, Issue 4, Page(s) 1865–1869

    Abstract: Infantile digital fibromatosis (IDF), also called inclusion body fibromatosis is an uncommon benign tumour occurring in the digits of young children. In about a third of cases, it is congenital and the diagnosis is based on the presence of peculiar ... ...

    Abstract Infantile digital fibromatosis (IDF), also called inclusion body fibromatosis is an uncommon benign tumour occurring in the digits of young children. In about a third of cases, it is congenital and the diagnosis is based on the presence of peculiar intracytoplasmic inclusions on histology. Recurrence rate post-surgery is high. However, spontaneous regression has been reported. We present a case of a 5-month-old infant who had excision of a right second toe mass, which has been present from birth. Histological examination revealed this to be infantile digital fibromatosis. To the best of our knowledge, no report of this has been made in Nigeria. It is important that this diagnosis be entertained in young children with masses on the digits as this will influence the management instituted.
    MeSH term(s) Female ; Fibroma/congenital ; Fibroma/pathology ; Fibroma/surgery ; Foot Diseases/pathology ; Humans ; Inclusion Bodies/pathology ; Infant ; Toes/pathology ; Treatment Outcome
    Language English
    Publishing date 2020-08-12
    Publishing country Uganda
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2240308-5
    ISSN 1729-0503 ; 1680-6905
    ISSN (online) 1729-0503
    ISSN 1680-6905
    DOI 10.4314/ahs.v20i4.42
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical predictors and outcome of bowel resection in paediatric intussusception.

    Ajao, Akinlabi E / Lawal, Taiwo A / Ogundoyin, Olakayode O / Olulana, Dare I

    African health sciences

    2020  Volume 20, Issue 3, Page(s) 1463–1470

    Abstract: Introduction: Surgery remains the mainstay in treating intussusception in developing countries, with a correspondingly high bowel resection rate despite a shift to non-operative reduction in high-income countries.: Objective: To assess factors ... ...

    Abstract Introduction: Surgery remains the mainstay in treating intussusception in developing countries, with a correspondingly high bowel resection rate despite a shift to non-operative reduction in high-income countries.
    Objective: To assess factors associated with bowel resection and the outcomes of resection in childhood intussusception.
    Methods: A review of children with intussusception between January 2006 and December 2015 at the University College Hospital, Ibadan, Nigeria. The patients were categorized based on the need for bowel resection and analysis done using the SPSS version 23.
    Results: 121 children were managed for intussusception during this period. 53 (43.8%) had bowel resection, 61 (50.4%) did not require resection and 7 (5.8%) were unknown. 40 (75.5%) of the resections were right hemi-colectomy. The presence of fever, abdominal pain, distension, rectal mass, age < 12 months, heart rate > 145/min and duration of symptoms > 2 days were associated with the need for bowel resection (p < 0.05). However, only age and abdominal pain independently predicted need for resection. Bowel resection was more associated with development of post-operative complications and prolonged hospital stay (p < 0.05).
    Conclusion: Infants presenting with abdominal pain and abdominal distension after two days of onset of symptoms were more likely to require bowel resection. Resection in intussusception significantly increased post-operative complications and length of hospital stay.
    MeSH term(s) Abdominal Pain/etiology ; Child ; Child, Preschool ; Digestive System Surgical Procedures/adverse effects ; Digestive System Surgical Procedures/methods ; Female ; Humans ; Incidence ; Infant ; Intussusception/diagnosis ; Intussusception/etiology ; Intussusception/surgery ; Length of Stay/statistics & numerical data ; Male ; Nigeria/epidemiology ; Postoperative Complications/epidemiology ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2020-12-15
    Publishing country Uganda
    Document type Journal Article
    ZDB-ID 2240308-5
    ISSN 1729-0503 ; 1680-6905
    ISSN (online) 1729-0503
    ISSN 1680-6905
    DOI 10.4314/ahs.v20i3.52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Outcome of Management of Neonatal Intestinal Obstruction at a Tertiary Center in Nigeria.

    Ogundoyin, Olakayode Olaolu / Olulana, Dare I / Lawal, Taiwo A / Ajao, Akinlabi E

    Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society

    2018  Volume 25, Issue 2, Page(s) 163–166

    Abstract: Background: Intestinal obstruction in a newborn remains a significant emergency in pediatric surgery. Clinical presentation is often subtle with sudden deterioration of their clinical states. Clinical outcome in the developing countries is poor owing to ...

    Abstract Background: Intestinal obstruction in a newborn remains a significant emergency in pediatric surgery. Clinical presentation is often subtle with sudden deterioration of their clinical states. Clinical outcome in the developing countries is poor owing to a variety of factors.
    Objective: The objective of this study is to identify the factors affecting the management outcome in our environment.
    Patients and methods: Data on clinical presentation, management, and outcome of all neonates managed for intestinal obstruction over a 13-year period at a tertiary center in Nigeria were retrospectively reviewed. Analysis of factors affecting the management outcome was also performed.
    Results: One hundred and seventeen neonates comprising 85 (72.7%) boys and 32 (27.3%) girls were managed for intestinal obstruction. The age at presentation ranged from 0 to 29 days, with a mean of 6.86 ± 8.4 days. Seventy-five (64.1%) patients presented within a week of onset of symptoms and 42 (35.9%) patients later. Eighty-five patients (72.6%) presented with symptoms from birth. The most common causes of intestinal obstruction included anorectal malformation in 62 (53%) neonates and Hirschsprung's disease in 16 (13.7%) neonates. Other causes included obstructed inguinoscrotal hernias, duodenal atresia, jejunoileal atresia, malrotation, and annular pancreas. Eleven patients died with a mortality rate of 9.4%. The age at presentation (
    Conclusion: Early presentation and postoperative complications significantly affected the morbidity and mortality associated with the management of neonates with intestinal obstruction.
    Language English
    Publishing date 2018-11-17
    Publishing country India
    Document type Journal Article
    ZDB-ID 2641743-1
    ISSN 2278-7100 ; 1117-6806
    ISSN (online) 2278-7100
    ISSN 1117-6806
    DOI 10.4103/njs.NJS_11_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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