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  1. Article ; Online: Reply to the Editor- Cardiac denervation and its consequences in heart disease.

    Chung, Wei-Hsin / Ajijola, Olujimi A

    Heart rhythm

    2024  Volume 21, Issue 4, Page(s) 507–508

    MeSH term(s) Humans ; Heart ; Heart Diseases ; Denervation
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Letter
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2023.12.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chronic Kidney Disease: A Nerve-Racking Situation for the Heart.

    Ajijola, Olujimi A

    Circulation research

    2022  Volume 130, Issue 6, Page(s) 829–830

    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation ; Female ; Humans ; Male ; Renal Insufficiency, Chronic
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.122.320858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The promise of cardiac neuromodulation: can computational modelling bridge the gap?

    Liu, Michael B / Ajijola, Olujimi A

    The Journal of physiology

    2023  Volume 601, Issue 17, Page(s) 3693–3694

    MeSH term(s) Heart ; Autonomic Nervous System ; Computer Simulation
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP285309
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mechanism of Ventricular Tachycardia Occurring in Chronic Myocardial Infarction Scar.

    Donahue, J Kevin / Chrispin, Jonathan / Ajijola, Olujimi A

    Circulation research

    2024  Volume 134, Issue 3, Page(s) 328–342

    Abstract: Cardiac arrest is the leading cause of death in the more economically developed countries. Ventricular tachycardia associated with myocardial infarct is a prominent cause of cardiac arrest. Ventricular arrhythmias occur in 3 phases of infarction: during ... ...

    Abstract Cardiac arrest is the leading cause of death in the more economically developed countries. Ventricular tachycardia associated with myocardial infarct is a prominent cause of cardiac arrest. Ventricular arrhythmias occur in 3 phases of infarction: during the ischemic event, during the healing phase, and after the scar matures. Mechanisms of arrhythmias in these phases are distinct. This review focuses on arrhythmia mechanisms for ventricular tachycardia in mature myocardial scar. Available data have shown that postinfarct ventricular tachycardia is a reentrant arrhythmia occurring in circuits found in the surviving myocardial strands that traverse the scar. Electrical conduction follows a zigzag course through that area. Conduction velocity is impaired by decreased gap junction density and impaired myocyte excitability. Enhanced sympathetic tone decreases action potential duration and increases sarcoplasmic reticular calcium leak and triggered activity. These elements of the ventricular tachycardia mechanism are found diffusely throughout scar. A distinct myocyte repolarization pattern is unique to the ventricular tachycardia circuit, setting up conditions for classical reentry. Our understanding of ventricular tachycardia mechanisms continues to evolve as new data become available. The ultimate use of this information would be the development of novel diagnostics and therapeutics to reliably identify at-risk patients and prevent their ventricular arrhythmias.
    MeSH term(s) Humans ; Cicatrix ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/etiology ; Arrhythmias, Cardiac/complications ; Myocardial Infarction/complications ; Heart Arrest/complications ; Electrocardiography
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.123.321553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Painless cardioversion/defibrillation: Are we there yet?

    Do, Duc / Ajijola, Olujimi A

    Heart rhythm

    2022  Volume 19, Issue 7, Page(s) 1174–1175

    MeSH term(s) Atrial Fibrillation/therapy ; Electric Countershock ; Electrodes ; Humans
    Language English
    Publishing date 2022-04-04
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2022.03.1231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Irreversible electroporation for cardiac ablation: Optimizing cell type-specific effects.

    Masuyama, Kiyoshi / Ajijola, Olujimi A

    Journal of cardiovascular electrophysiology

    2022  Volume 33, Issue 9, Page(s) 2062–2063

    MeSH term(s) Ablation Techniques/adverse effects ; Catheter Ablation/adverse effects ; Electroporation ; Humans
    Language English
    Publishing date 2022-08-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Afferents Nerves in Atrial Fibrillation: Going Beyond Fight or Flight.

    Hanna, Peter / Ajijola, Olujimi A

    JACC. Clinical electrophysiology

    2021  Volume 8, Issue 2, Page(s) 165–167

    MeSH term(s) Atrial Fibrillation/physiopathology ; Atrial Fibrillation/surgery ; Autonomic Nervous System/physiopathology ; Catheter Ablation ; Humans
    Language English
    Publishing date 2021-12-22
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2022.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Editorial commentary: Atrial fibrillation and stroke: The journey continues.

    Chung, Wei-Hsin / Ajijola, Olujimi A

    Trends in cardiovascular medicine

    2021  Volume 33, Issue 1, Page(s) 30–31

    MeSH term(s) Humans ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/therapy ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/etiology ; Stroke Volume ; Heart Failure ; Prognosis
    Language English
    Publishing date 2021-12-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2021.12.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Combined Imaging and In Silico Simulations to Predict Ventricular Arrhythmia Risk in Nonischemic Cardiomyopathy.

    Akinrimisi, Olumuyiwa P / Ajijola, Olujimi A

    JACC. Clinical electrophysiology

    2021  Volume 7, Issue 2, Page(s) 250–252

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/epidemiology ; Cardiomyopathy, Dilated ; Computer Simulation ; Contrast Media ; Gadolinium ; Humans
    Chemical Substances Contrast Media ; Gadolinium (AU0V1LM3JT)
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2020.11.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Sinus arrest during radiofrequency ablation from the inferoseptal process of the left ventricle: Proposed mechanisms of an uncommon finding.

    Mircea, Andrei Alexandru / Mori, Shumpei / Ajijola, Olujimi A / Khakpour, Houman

    HeartRhythm case reports

    2023  Volume 9, Issue 5, Page(s) 291–295

    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2023.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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