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  1. Article ; Online: Seismic imaging of slab metamorphism and genesis of intermediate-depth intraslab earthquakes

    Akira Hasegawa / Junichi Nakajima

    Progress in Earth and Planetary Science, Vol 4, Iss 1, Pp 1-

    2017  Volume 31

    Abstract: Abstract We review studies of intermediate-depth seismicity and seismic imaging of the interior of subducting slabs in relation to slab metamorphism and their implications for the genesis of intermediate-depth earthquakes. Intermediate-depth events form ... ...

    Abstract Abstract We review studies of intermediate-depth seismicity and seismic imaging of the interior of subducting slabs in relation to slab metamorphism and their implications for the genesis of intermediate-depth earthquakes. Intermediate-depth events form a double seismic zone in the depth range of c. 40–180 km, which occur only at locations where hydrous minerals are present, and are particularly concentrated along dehydration reaction boundaries. Recent studies have revealed detailed spatial distributions of these events and a close relationship with slab metamorphism. Pressure–temperature paths of the crust for cold slabs encounter facies boundaries with large H2O production rates and positive total volume change, which are expected to cause highly active seismicity near the facies boundaries. A belt of upper-plane seismicity in the crust nearly parallel to 80–90 km depth contours of the slab surface has been detected in the cold Pacific slab beneath eastern Japan, and is probably caused by slab crust dehydration with a large H2O production rate. A seismic low-velocity layer in the slab crust persists down to the depth of this upper-plane seismic belt, which provides evidence for phase transformation of dehydration at this depth. Similar low-velocity subducting crust closely related with intraslab seismicity has been detected in several other subduction zones. Seismic tomography studies in NE Japan and northern Chile also revealed the presence of a P-wave low-velocity layer along the lower plane of a double seismic zone. However, in contrast to predictions based on the serpentinized mantle, S-wave velocity along this layer is not low. Seismic anisotropy and pore aspect ratio may play a role in generating this unique structure. Although further validation is required, observations of these distinct low P-wave velocities along the lower seismic plane suggest the presence of hydrated rocks or fluids within that layer. These observations support the hypothesis that dehydration-derived H2O causes intermediate-depth ...
    Keywords Internal slab structure ; Slab metamorphism ; Dehydration-related embrittlement ; Intermediate-depth earthquake ; Intraslab earthquake ; Earthquake generation mechanism ; Geography. Anthropology. Recreation ; G ; Geology ; QE1-996.5
    Subject code 550 ; 500
    Language English
    Publishing date 2017-04-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Tremor activity inhibited by well-drained conditions above a megathrust

    Junichi Nakajima / Akira Hasegawa

    Nature Communications, Vol 7, Iss 1, Pp 1-

    2016  Volume 7

    Abstract: Low-frequency earthquakes (LFEs) in megathrusts are due to weak shear strength and high fluid pressure, but controls on LFE location remain unclear. Nakajima and Hasegawa show that LFE occurrence is limited to beneath unmetamorphosed undrained portions ... ...

    Abstract Low-frequency earthquakes (LFEs) in megathrusts are due to weak shear strength and high fluid pressure, but controls on LFE location remain unclear. Nakajima and Hasegawa show that LFE occurrence is limited to beneath unmetamorphosed undrained portions of the overlying plate.
    Keywords Science ; Q
    Language English
    Publishing date 2016-12-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: SkewC

    Imad Abugessaisa / Akira Hasegawa / Shuhei Noguchi / Melissa Cardon / Kazuhide Watanabe / Masataka Takahashi / Harukazu Suzuki / Shintaro Katayama / Juha Kere / Takeya Kasukawa

    iScience, Vol 25, Iss 2, Pp 103777- (2022)

    Identifying cells with skewed gene body coverage in single-cell RNA sequencing data

    2022  

    Abstract: Summary: The analysis and interpretation of single-cell RNA sequencing (scRNA-seq) experiments are compromised by the presence of poor-quality cells. For meaningful analyses, such poor-quality cells should be excluded as they introduce noise in the data. ...

    Abstract Summary: The analysis and interpretation of single-cell RNA sequencing (scRNA-seq) experiments are compromised by the presence of poor-quality cells. For meaningful analyses, such poor-quality cells should be excluded as they introduce noise in the data. We introduce SkewC, a quality-assessment tool, to identify skewed cells in scRNA-seq experiments. The tool’s methodology is based on the assessment of gene coverage for each cell, and its skewness as a quality measure; the gene body coverage is a unique characteristic for each protocol, and different protocols yield highly different coverage profiles. This tool is designed to avoid misclustering or false clusters by identifying, isolating, and removing cells with skewed gene body coverage profiles. SkewC is capable of processing any type of scRNA-seq dataset, regardless of the protocol. We envision SkewC as a distinctive QC method to be incorporated into scRNA-seq QC processing to preclude the possibility of scRNA-seq data misinterpretation.
    Keywords Biological sciences ; Cell biology ; Biocomputational method ; Biological sciences research methodologies ; Science ; Q
    Subject code 612
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Impact of air–sea coupling on the probability of occurrence of heat waves in Japan

    Akira Hasegawa / Yukiko Imada / Hideo Shiogama / Masato Mori / Hiroaki Tatebe / Masahiro Watanabe

    Progress in Earth and Planetary Science, Vol 7, Iss 1, Pp 1-

    2020  Volume 12

    Abstract: Abstract In extreme event attribution, which aims to answer whether and to what extent a particular extreme weather event can be attributed to global warming, the probability of an event is generally estimated through large ensemble simulations, using an ...

    Abstract Abstract In extreme event attribution, which aims to answer whether and to what extent a particular extreme weather event can be attributed to global warming, the probability of an event is generally estimated through large ensemble simulations, using an atmospheric general circulation model (AGCM). In islands, such as Japan, it has been considered that surface air temperature (SAT) can be significantly affected by the surrounding sea surface temperature (SST), which mostly is affected by atmospheric circulation at mid- and high-latitudes. Therefore, the absence of SST responses to atmospheric variability in AGCMs impacts the estimation of the occurrence of extreme events, such as heat waves in Japan. In this study, we examined the impact of air–sea coupling on the probability of occurrence of severe heat waves that occurred in Japan in the summer of 2010 by analyzing the probability differences obtained from AGCM and coupled general circulation model (CGCM) large-ensemble experiments. The observed ocean temperature, salinity, and sea ice were assimilated in the 100-member CGCM experiments, as they were assigned as boundary conditions in the 100-member AGCM experiments. The SAT around Japan in the northern summer is largely related to the Bonin high, whose interannual variability is largely affected by the Silk Road and Pacific-Japan (PJ) pattern teleconnections in the real world. The SAT anomaly over Japan was related to the pressure variability due to the Silk Road and PJ patterns in the CGCM experiment. By contrast, the SAT over Japan simulated by AGCM was less sensitive to such pressure variability, and the SAT ensemble spread became narrower in AGCM. The results suggest that the probability of occurrence of the 2010 heat wave in Japan would tend to be underestimated by the AGCM ensemble compared to the CGCM ensemble, provided that the ensemble averages of the SAT anomalies were equal between CGCM and AGCM experiments. This study raised the issue of the absence of SST response to atmospheric variability in ...
    Keywords Atmosphere-ocean coupling ; Heat waves ; Probability density function ; Atmospheric internal variability ; Silk Road wave train ; Pacific-Japan pattern ; Geography. Anthropology. Recreation ; G ; Geology ; QE1-996.5
    Subject code 551
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Two Nicotiana occidentalis accessions enable gene identification for Type II hybrid lethality by the cross to N. sylvestris

    Kenji Kawaguchi / Yuichiro Ohya / Maho Maekawa / Takahiro Iizuka / Akira Hasegawa / Kumpei Shiragaki / Hai He / Masayuki Oda / Toshinobu Morikawa / Shuji Yokoi / Takahiro Tezuka

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 8

    Abstract: Abstract Hybrid lethality, meaning the death of F1 hybrid seedlings, has been observed in many plant species, including Nicotiana. Previously, we have revealed that hybrids of the selected Nicotiana occidentalis accession and N. tabacum, an ... ...

    Abstract Abstract Hybrid lethality, meaning the death of F1 hybrid seedlings, has been observed in many plant species, including Nicotiana. Previously, we have revealed that hybrids of the selected Nicotiana occidentalis accession and N. tabacum, an allotetraploid with S and T genomes, exhibited lethality characterized by the fading of shoot color. The lethality was suggested to be controlled by alleles of loci on the S and T genomes derived from N. sylvestris and N. tomentosiformis, respectively. Here, we extended the analysis of hybrid lethality using other two accessions of N. occidentalis identified from the five tested accessions. The two accessions were crossed with N. tabacum and its two progenitors, N. sylvestris and N. tomentosiformis. After crosses with N. tabacum, the two N. occidentalis accessions yielded inviable hybrid seedlings whose lethality was characterized by the fading of shoot color, but only the T genome of N. tabacum was responsible for hybrid lethality. Genetic analysis indicated that first-mentioned N. occidentalis accession carries a single gene causing hybrid lethality by allelic interaction with the S genome.
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: RCP8.5-Based Future Flood Hazard Analysis for the Lower Mekong River Basin

    Edangodage Duminda Pradeep Perera / Takahiro Sayama / Jun Magome / Akira Hasegawa / Yoichi Iwami

    Hydrology, Vol 4, Iss 4, p

    2017  Volume 55

    Abstract: Climatic variations caused by the excessive emission of greenhouse gases are likely to change the patterns of precipitation, runoff processes, and water storage of river basins. Various studies have been conducted based on precipitation outputs of the ... ...

    Abstract Climatic variations caused by the excessive emission of greenhouse gases are likely to change the patterns of precipitation, runoff processes, and water storage of river basins. Various studies have been conducted based on precipitation outputs of the global scale climatic models under different emission scenarios. However, there is a limitation in regional- and local-scale hydrological analysis on extreme floods with the combined application of high-resolution atmospheric general circulation models’ (AGCM) outputs and physically-based hydrological models (PBHM). This study has taken an effort to overcome that limitation in hydrological analysis. The present and future precipitation, river runoff, and inundation distributions for the Lower Mekong Basin (LMB) were analyzed to understand hydrological changes in the LMB under the RCP8.5 scenario. The downstream area beyond the Kratie gauging station, located in the Cambodia and Vietnam flood plains was considered as the LMB in this study. The bias-corrected precipitation outputs of the Japan Meteorological Research Institute atmospheric general circulation model (MRI-AGCM3.2S) with 20 km horizontal resolution were utilized as the precipitation inputs for basin-scale hydrological simulations. The present climate (1979–2003) was represented by the AMIP-type simulations while the future (2075–2099) climatic conditions were obtained based on the RCP8.5 greenhouse gas scenario. The entire hydrological system of the Mekong basin was modelled by the block-wise TOPMODEL (BTOP) hydrological model with 20 km resolution, while the LMB area was modelled by the rainfall-runoff-inundation (RRI) model with 2 km resolution, specifically to analyze floods under the aforementioned climatic conditions. The comparison of present and future river runoffs, inundation distributions and inundation volume changes were the outcomes of the study, which can be supportive information for the LMB flood management, water policy, and water resources development.
    Keywords climate change ; flood hazards ; high-resolution AGCM ; inundation analysis ; Lower Mekong river basin ; Science ; Q
    Subject code 550 ; 910
    Language English
    Publishing date 2017-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Author Correction

    Mathys Grapotte / Manu Saraswat / Chloé Bessière / Christophe Menichelli / Jordan A. Ramilowski / Jessica Severin / Yoshihide Hayashizaki / Masayoshi Itoh / Michihira Tagami / Mitsuyoshi Murata / Miki Kojima-Ishiyama / Shohei Noma / Shuhei Noguchi / Takeya Kasukawa / Akira Hasegawa / Harukazu Suzuki / Hiromi Nishiyori-Sueki / Martin C. Frith / FANTOM consortium /
    Clément Chatelain / Piero Carninci / Michiel J. L. de Hoon / Wyeth W. Wasserman / Laurent Bréhélin / Charles-Henri Lecellier

    Nature Communications, Vol 13, Iss 1, Pp 1-

    Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

    2022  Volume 1

    Keywords Science ; Q
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Soliton Management for Ultra-high Speed Telecommunications

    Vladimir N. Serkin / Akira Hasegawa

    Ciencia Ergo Sum, Vol 8, Iss

    2001  Volume 3

    Abstract: La metodología desarrollada provee un método sistemático de encontrar un número infinito de las novedosas islas solitónicas (soliton islands) estables, brillantes y obscuras en un mar de olas solitarias, para la ecuación no lineal de Schrödinger con ... ...

    Abstract La metodología desarrollada provee un método sistemático de encontrar un número infinito de las novedosas islas solitónicas (soliton islands) estables, brillantes y obscuras en un mar de olas solitarias, para la ecuación no lineal de Schrödinger con dispersión y no linealidad variables y con ganancia o absorción. Se muestra que los solitones existen sólo bajo ciertas condiciones y las funciones paramétricas que describen la dispersión, la no linealidad, la ganacia o absorción no homógenea, no pueden ser electas independientemente. Se han descubierto los regímenes de manejo fundamental solitónico para comunicaciones a velocidades ultra-rápidas a través de fibras ópticas.
    Keywords telecomunicaciones en fibras ópticas ; solitones ; Science ; Q ; Social Sciences ; H
    Language English
    Publishing date 2001-01-01T00:00:00Z
    Publisher Universidad Autonoma del Estado de Mexico
    Document type Article ; Online
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  9. Article ; Online: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

    Mathys Grapotte / Manu Saraswat / Chloé Bessière / Christophe Menichelli / Jordan A. Ramilowski / Jessica Severin / Yoshihide Hayashizaki / Masayoshi Itoh / Michihira Tagami / Mitsuyoshi Murata / Miki Kojima-Ishiyama / Shohei Noma / Shuhei Noguchi / Takeya Kasukawa / Akira Hasegawa / Harukazu Suzuki / Hiromi Nishiyori-Sueki / Martin C. Frith / FANTOM consortium /
    Clément Chatelain / Piero Carninci / Michiel J. L. de Hoon / Wyeth W. Wasserman / Laurent Bréhélin / Charles-Henri Lecellier

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 18

    Abstract: Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are ... ...

    Abstract Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.
    Keywords Science ; Q
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

    Tsukasa Kouno / Jonathan Moody / Andrew Tae-Jun Kwon / Youtaro Shibayama / Sachi Kato / Yi Huang / Michael Böttcher / Efthymios Motakis / Mickaël Mendez / Jessica Severin / Joachim Luginbühl / Imad Abugessaisa / Akira Hasegawa / Satoshi Takizawa / Takahiro Arakawa / Masaaki Furuno / Naveen Ramalingam / Jay West / Harukazu Suzuki /
    Takeya Kasukawa / Timo Lassmann / Chung-Chau Hon / Erik Arner / Piero Carninci / Charles Plessy / Jay W. Shin

    Nature Communications, Vol 10, Iss 1, Pp 1-

    2019  Volume 12

    Abstract: Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system. ...

    Abstract Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system.
    Keywords Science ; Q
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Nature Portfolio
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