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Article ; Online: Osmolyte effect on enzymatic stability and reaction equilibrium of formate dehydrogenase.

Gajardo-Parra, Nicolás F / Akrofi-Mantey, Harold / Ascani, Moreno / Cea-Klapp, Esteban / Garrido, José Matias / Sadowski, Gabriele / Held, Christoph

Physical chemistry chemical physics : PCCP

2022  Volume 24, Issue 45, Page(s) 27930–27939

Abstract: Osmolytes are well-known biocatalyst stabilisers as they promote the folded state of proteins, and a stabilised biocatalyst might also improve reaction kinetics. In this work, the influence of four osmolytes (betaine, glycerol, trehalose, and ... ...

Abstract Osmolytes are well-known biocatalyst stabilisers as they promote the folded state of proteins, and a stabilised biocatalyst might also improve reaction kinetics. In this work, the influence of four osmolytes (betaine, glycerol, trehalose, and trimethylamine
MeSH term(s) Formate Dehydrogenases/chemistry ; Betaine/chemistry ; Methylamines/chemistry ; Thermodynamics
Chemical Substances trimethyloxamine (FLD0K1SJ1A) ; Formate Dehydrogenases (EC 1.17.1.9) ; Betaine (3SCV180C9W) ; Methylamines
Language English
Publishing date 2022-11-23
Publishing country England
Document type Journal Article
ZDB-ID 1476244-4
ISSN 1463-9084 ; 1463-9076
ISSN (online) 1463-9084
ISSN 1463-9076
DOI 10.1039/d2cp04011e
Database MEDical Literature Analysis and Retrieval System OnLINE

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