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  1. Article ; Online: A Large Splenic Epidermoid Cyst Initially Misdiagnosed as a Hydatid Cyst.

    Aloqaily, Mohammed / Al Hayek, Sa'ed / Shaf'ei, Moayad / Almaaitah, Huthaifa W / AlShammas, Faris / Daradkeh, Salam

    The American journal of case reports

    2023  Volume 24, Page(s) e941585

    Abstract: BACKGROUND Splenic cysts are classified as either parasitic or non-parasitic cysts, with both types sharing similarities in their clinical presentation and imaging findings. Most splenic cysts are of parasitic origin, while non-parasitic splenic cysts ... ...

    Abstract BACKGROUND Splenic cysts are classified as either parasitic or non-parasitic cysts, with both types sharing similarities in their clinical presentation and imaging findings. Most splenic cysts are of parasitic origin, while non-parasitic splenic cysts are less common. Splenic epidermoid cysts (SECs) are a rare subtype of non-parasitic cysts and compromise only around 10% of them. CASE REPORT In this paper we present a case of 22-year-old man with no significant past clinical history, who presented with non-specific, vague symptoms, including persistent left upper-quadrant pain and discomfort for the last 2 years. A physical examination and extensive laboratory tests were inconclusive. Subsequently, the patient underwent multiple imaging studies including ultrasonography and computed tomography (CT) scan of the abdomen. His ultrasonographic findings were consistent with the diagnosis of hydatid cyst, which was further emphasized by its frequent occurrence in clinical practice, as our country is considered an endemic region. In light of this, he underwent laparoscopic splenectomy following percutaneous cyst drainage. The consequent histopathological examination revealed the diagnosis of splenic epidermoid cysts. CONCLUSIONS When encountering splenic cysts in regions where parasitic infections are endemic, special attention is needed, as physical examination, laboratory tests, and imaging studies alone are insufficient to differentiate among the types of cysts. Histopathological examination remains the diagnostic tool of choice, particularly when imaging findings are inconclusive. Splenectomy, with either a laparoscopic or open approach, is the treatment of choice for splenic cysts to prevent recurrence as well as other potential catastrophic complications.
    MeSH term(s) Humans ; Male ; Young Adult ; Diagnostic Errors ; Echinococcosis/diagnosis ; Epidermal Cyst/diagnosis ; Epidermal Cyst/surgery ; Epidermal Cyst/pathology ; Splenic Diseases/diagnosis ; Splenic Diseases/surgery
    Language English
    Publishing date 2023-12-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.941585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A successfully treated gastric mucormycosis in an immunocompetent patient: Case report and literature review.

    Albtoosh, Asma Salameh / Shaf'ei, Moayad / Al Hayek, Sa'ed / Ramdan, Lara Ibrahim / Abu Shahin, Nisreen / Alzyoud, Mohammad / Farah, Randa

    Clinical case reports

    2023  Volume 11, Issue 6, Page(s) e7540

    Abstract: Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can ... ...

    Abstract Mucormycosis is an opportunistic fungal infection that usually affects patients with diabetes mellitus or immunosuppression. The fungus invades the nearby blood vessels leading to thrombosis and necrosis of the organs involved. Although Mucorales can invade any organ in the body, the gastrointestinal system is an uncommon site for infection. Mucormycosis is a fatal infection, and prompt intervention is required to ensure survival. In this report, we present a case of a 46-year-old man with history of valve replacement surgery on warfarin, who admitted with abdominal pain and life-threatening gastrointestinal bleeding. Esophagogastroduodenoscopy revealed an active gastric ulcer bleeding, and the diagnosis of mucormycosis infection was confirmed with direct microscopy and histopathological evaluation from a tissue
    Language English
    Publishing date 2023-06-17
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The role of adenosine receptor ligands on inflammatory pain: possible modulation of TRPV1 receptor function.

    Haddad, Mansour / Alsalem, Mohammad / Aldossary, Sara A / Kalbouneh, Heba / Jaffal, Sahar M / Alshawabkeh, Qusai / Al Hayek, Sa'ed / Abdelhai, Omar / Barakat, Noor A / El-Salem, Khalid

    Inflammopharmacology

    2022  Volume 31, Issue 1, Page(s) 337–347

    Abstract: Chronic pain has a debilitating consequences on health and lifestyle. The currently available analgesics are often ineffective and accompanied by undesirable adverse effects. Although adenosine receptors (AR) activation can affect nociceptive, ... ...

    Abstract Chronic pain has a debilitating consequences on health and lifestyle. The currently available analgesics are often ineffective and accompanied by undesirable adverse effects. Although adenosine receptors (AR) activation can affect nociceptive, inflammatory, and neuropathic pain states, the specific regulatory functions of its subtypes (A
    MeSH term(s) Rats ; Male ; Animals ; Rats, Sprague-Dawley ; Calcium/metabolism ; TRPV Cation Channels ; Chronic Pain ; Receptors, Purinergic P1 ; Antineoplastic Agents
    Chemical Substances TRPV1 receptor ; Calcium (SY7Q814VUP) ; TRPV Cation Channels ; Receptors, Purinergic P1 ; Antineoplastic Agents ; Trpv1 protein, rat
    Language English
    Publishing date 2022-12-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1080058-x
    ISSN 1568-5608 ; 0925-4692
    ISSN (online) 1568-5608
    ISSN 0925-4692
    DOI 10.1007/s10787-022-01127-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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