Article: Vancomycin flushing syndrome in orthopaedic practice: A case report.
2023 Volume 14, Issue 10, Page(s) 771–775
Abstract: Background: Vancomycin flushing syndrome (VFS), also known as red man syndrome, is an allergic reaction to vancomycin. It typically presents as a rash on the face, neck, and upper torso after intravenous administration of vancomycin. VFS is blamed on ... ...
Abstract | Background: Vancomycin flushing syndrome (VFS), also known as red man syndrome, is an allergic reaction to vancomycin. It typically presents as a rash on the face, neck, and upper torso after intravenous administration of vancomycin. VFS is blamed on rapid intravenous infusion of vancomycin during management and rarely happens after local use. A review of the literature showed that in the last 23 years, 4 such cases have been reported. Here, we add another case of VFS developed after slow local absorption of vancomycin in cement beads. Case summary: A 44-year-old male with a known case of hypertension, no history of allergies to medications, and a history of chronic osteomyelitis of the right tibia with discharging sinus over the anterolateral aspect of the leg. The pus culture grew Conclusion: VFS can occur not only after rapid intravenous injection of vancomycin but also with local release, as in our case. As orthopaedic surgeons routinely use vancomycin with polymethyl methacrylate in chronic osteomyelitis and revision arthroplasty, they should be aware of such a complication occurring. |
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Language | English |
Publishing date | 2023-10-18 |
Publishing country | United States |
Document type | Case Reports |
ZDB-ID | 2649712-8 |
ISSN | 2218-5836 |
ISSN | 2218-5836 |
DOI | 10.5312/wjo.v14.i10.771 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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