LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 209

Search options

  1. Article ; Online: The glymphatic system for neurosurgeons: a scoping review.

    Al Masri, Mohammad / Corell, Alba / Michaëlsson, Isak / Jakola, Asgeir S / Skoglund, Thomas

    Neurosurgical review

    2024  Volume 47, Issue 1, Page(s) 61

    Abstract: The discovery of the glymphatic system has revolutionized our understanding of cerebrospinal fluid (CSF) circulation and interstitial waste clearance in the brain. This scoping review aims to synthesize the current literature on the glymphatic system's ... ...

    Abstract The discovery of the glymphatic system has revolutionized our understanding of cerebrospinal fluid (CSF) circulation and interstitial waste clearance in the brain. This scoping review aims to synthesize the current literature on the glymphatic system's role in neurosurgical conditions and its potential as a therapeutic target. We conducted a comprehensive search in PubMed and Scopus databases for studies published between January 1, 2012, and October 31, 2023. Studies were selected based on their relevance to neurosurgical conditions and glymphatic function, with both animal and human studies included. Data extraction focused on the methods for quantifying glymphatic function and the main results. A total of 67 articles were included, covering conditions such as idiopathic normal pressure hydrocephalus (iNPH), idiopathic intracranial hypertension (IIH), subarachnoid hemorrhage (SAH), stroke, intracranial tumors, and traumatic brain injury (TBI). Significant glymphatic dysregulation was noted in iNPH and IIH, with evidence of impaired CSF dynamics and delayed clearance. SAH studies indicated glymphatic dysfunction with the potential therapeutic effects of nimodipine and tissue plasminogen activator. In stroke, alterations in glymphatic activity correlated with the extent of edema and neurological recovery. TBI studies highlighted the role of the glymphatic system in post-injury cognitive outcomes. Results indicate that the regulation of aquaporin-4 (AQP4) channels is a critical target for therapeutic intervention. The glymphatic system plays a critical role in the pathophysiology of various neurosurgical conditions, influencing brain edema and CSF dynamics. Targeting the regulation of AQP4 channels presents as a significant therapeutic strategy. Although promising, the translation of these findings into clinical practice requires further human studies. Future research should focus on establishing non-invasive biomarkers for glymphatic function and exploring the long-term effects of glymphatic dysfunction.
    MeSH term(s) Animals ; Humans ; Glymphatic System ; Neurosurgeons ; Tissue Plasminogen Activator ; Brain ; Subarachnoid Hemorrhage ; Brain Injuries, Traumatic/surgery ; Hydrocephalus ; Stroke
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2024-01-23
    Publishing country Germany
    Document type Review ; Journal Article
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-024-02291-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Consumers' perception of novel foods and the impact of heuristics and biases: A systematic review.

    Monaco, Alessandro / Kotz, Johannes / Al Masri, Mirna / Allmeta, Anila / Purnhagen, Kai P / König, Laura M

    Appetite

    2024  Volume 196, Page(s) 107285

    Abstract: According to the definition adopted in the European Union, novel foods are foods that were not consumed to a significant degree within the Union before May 15, 1997. This includes cultivated meat and insects. Novel foods are meant to play a critical role ...

    Abstract According to the definition adopted in the European Union, novel foods are foods that were not consumed to a significant degree within the Union before May 15, 1997. This includes cultivated meat and insects. Novel foods are meant to play a critical role in the transition towards sustainable food systems. However, their success depends on whether and to what extent they will be incorporated into the diets at the population level. This review investigates consumers' perception of novel food products by narratively synthesising results on the influence of heuristics and biases triggered by emotions, personality traits, and socio-cultural factors. Empirical studies conducted in Western countries and published in English after 1997 were eligible, which led to 182 studies being included. Notably, most included studies focused on insects and cultivated meat. Disgust and fear are shown to be the main emotions driving rejection of novel foods, together with food neophobia and specific cultural norms common across countries included in the scope of the review. Familiarity with novel foods and curiosity both led to higher acceptance. Despite being investigated directly in a minority of studies, heuristics and related biases mostly fell under the "affect," the "natural-is-better," and the "trust" heuristics. The review also discusses to what extent consumers' perception reflects in the regulatory framework applicable to novel foods in the European Union, how it influences the regulation of insects and cultivated meat and which lessons can be drawn for the future of the regulatory framework.
    MeSH term(s) Animals ; Humans ; Heuristics ; Food ; Insecta ; Bias ; Perception ; Consumer Behavior
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2024.107285
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: A nonossifying fibroma of the femoral neck treated with curettage and dynamic hip screw with free fibular bone graft: a case report.

    Al Masri, Mohamad / Muhammed, Hussain / Alrezej, Ola Mahmoud / Alfrouh, Ameen Esa

    Annals of medicine and surgery (2012)

    2023  Volume 86, Issue 1, Page(s) 497–500

    Abstract: Introduction and importance: Nonossifying fibroma (NOF) is a benign fibrogenic lesion that is related to dysfunctional ossification and one of the most common benign bone tumors in childhood with incidence rate of 30-40% of skeletally immature children.! ...

    Abstract Introduction and importance: Nonossifying fibroma (NOF) is a benign fibrogenic lesion that is related to dysfunctional ossification and one of the most common benign bone tumors in childhood with incidence rate of 30-40% of skeletally immature children.
    Presentation of case: A 25-year-old female with left hip pain for the past 2 months, which was treated conservatively, presented with severe pain in the hip. X-ray showed a pathologic fracture in the neck of the femur with underlying lesion. MRI showed an osteolytic lesion in neck of the femur. Curettage of the lesion was done with free fibular bone graft and stabilized by Dynamic Hip Screw and specimen sent to pathology. The pathology report consisted with NOF. No-weight bearing for 8 weeks with physical rehabilitation were ordered and six months later the patient had a full range of motion and healed fracture.
    Clinical discussion\conclusion: This study revealed that the surgical treatment with bone graft for pathologic femoral neck fracture and underlying NOF allowed a quick return to mobility and can be fixed sufficiently to achieve excellent postoperative recovery.
    Language English
    Publishing date 2023-11-16
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000001451
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Mucormycosis: The hidden and forgotten disease.

    Darwish, Rula M / AlMasri, Mohammad / Al-Masri, Mahmoud M

    Journal of applied microbiology

    2022  Volume 132, Issue 6, Page(s) 4042–4057

    Abstract: Mucormycosis is a rare but serious fungal infection caused by a group of moulds called mucormycetes. More attention has recently been paid to it due to its association with coronavirus disease 2019 (COVID-19). Thus, it is important to review the progress ...

    Abstract Mucormycosis is a rare but serious fungal infection caused by a group of moulds called mucormycetes. More attention has recently been paid to it due to its association with coronavirus disease 2019 (COVID-19). Thus, it is important to review the progress of studies on mucormycosis and highlight the important findings in relation to epidemiology, clinical manifestation, major risk factors, diagnostic strategies and management. An electronic literature search was performed in PubMed using the keywords: Rhizopus, Mucorales, mucormycosis, zygomycosis, zygomycetes, COVID-19, the drugs (azoles, posaconazole, isavuconazole, amphotericin B pharmaceutical preparations and caspofungin), combination therapy, diagnosis and clinical manifestations. Studies written in the English language from January 1960 to 2021 were considered for this review article. All search results were reviewed, and the relevance of each article was determined by the authors independently. The review emphasized the fact that the diagnosis of mucormycosis is difficult, it is necessary to have a high index of suspicion to identify it, surgical debridement should be done prior to the dissemination of infection to improve clinical outcomes and identifying underlying risk factors is important for proper treatment. Moreover, antifungal therapeutic options are few with polyenes and their combinations should be appropriate for empirical therapy while posaconazole and isavuconazole are best reserved for de-escalation, refractory cases or patients intolerant to amphotericin B.
    MeSH term(s) Amphotericin B/therapeutic use ; Antifungal Agents/therapeutic use ; COVID-19 ; Debridement ; Humans ; Mucorales ; Mucormycosis/diagnosis ; Mucormycosis/drug therapy ; Mucormycosis/epidemiology
    Chemical Substances Antifungal Agents ; Amphotericin B (7XU7A7DROE)
    Language English
    Publishing date 2022-02-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1358023-1
    ISSN 1365-2672 ; 1364-5072
    ISSN (online) 1365-2672
    ISSN 1364-5072
    DOI 10.1111/jam.15487
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Identifying modifiable factors associated with COVID-19 vaccine hesitancy and acceptance among cancer patients in Jordan.

    AlMasri, Rama / Al Masri, Mahmoud / Darwish, Rula / Ammar, Khawla / Safi, Yasmin

    Frontiers in oncology

    2023  Volume 13, Page(s) 1281994

    Abstract: Introduction: Vaccines stand amongst the most effective medical interventions for the management of infectious diseases, and are pivotal tools for public health. The acceptance of vaccines is heavily influenced by perceptions of efficacy, safety and ... ...

    Abstract Introduction: Vaccines stand amongst the most effective medical interventions for the management of infectious diseases, and are pivotal tools for public health. The acceptance of vaccines is heavily influenced by perceptions of efficacy, safety and other modifiable factors.
    Purpose: This cross-sectional study sought to identify and examine the modifiable factors that can help address COVID-19 vaccine hesitancy and acceptance among cancer patients.
    Methods: The study was conducted between February and April 2021 using an online survey questionnaire comprising of four domains. The survey was administered to cancer patients in Jordan.
    Results: Among the 1,029 cancer patients who completed the online questionnaire (response rate= 73%), 58% (n=597) expressed willingness (intent) to take the vaccine. Notably, 72.5% (n=433) of those intending to take the vaccine were currently undergoing treatment. Knowledge and awareness played a significant role, with 54.3% considering them essential for vaccine acceptance. Fear of infection significantly influenced vaccine acceptance (p<0.001), with 66.8% expressing concern about potential infections. Peer encouragement was also a crucial factor, as 82.4% regarded it as an important driver for influencing vaccine acceptance (p<0.001).
    Conclusion: Peer encouragement, awareness, and fear emerged as the primary modifiable factors associated with greater vaccine acceptance by patients with active malignancies. Study results suggest that providing personalized and tailored information about vaccinations, focusing on safety and potential interactions with cancer and its treatment, are potentially excellent strategies for improving vaccine acceptance among cancer patients.
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1281994
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Biological Evaluation of Xanthene and Thioxanthene Derivatives as Antioxidant, Anticancer, and COX Inhibitors.

    Abualhasan, Murad / Hawash, Mohammed / Aqel, Samah / Al-Masri, Motasem / Mousa, Ahmed / Issa, Linda

    ACS omega

    2023  Volume 8, Issue 41, Page(s) 38597–38606

    Abstract: Xanthene and thioxanthene analogues have been investigated for their potential as anticancer and anti-inflammatory agents. Additionally, cysteine analogues have been found to possess antioxidant, anti-inflammatory, and anticancer activities due to their ... ...

    Abstract Xanthene and thioxanthene analogues have been investigated for their potential as anticancer and anti-inflammatory agents. Additionally, cysteine analogues have been found to possess antioxidant, anti-inflammatory, and anticancer activities due to their role in cellular redox balance, scavenging of free radicals, and involvement in nucleophilic reactions and enzyme binding sites. In this study, we synthesized a library of tertiary alcohols derived from xanthene and thioxanthene, and further, some of these compounds were coupled with cysteine. The objective of this research was to explore the potential anticancer, antioxidant, and anti-inflammatory activities of the synthesized compounds. The synthesized compounds were subjected to test for anticancer, antioxidant, and anti-inflammatory activities. Results indicated that compound
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c05695
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Inverted appendix in a patient with colon cancer: a case report and long-term follow-up.

    Aljalabneh, Basim / Mureb, Amro / Aljundi, Nadeem / Al-Qasem, Kholoud / Al-Masri, Mahmoud

    Journal of surgical case reports

    2023  Volume 2023, Issue 4, Page(s) rjad206

    Abstract: Appendiceal inversion is a rare entity that can potentially mimic serious pathology and provide diagnostic uncertainty. They are mostly diagnosed intraoperatively or during endoscopies and scans for other reasons. We report a case of an asymptomatic ... ...

    Abstract Appendiceal inversion is a rare entity that can potentially mimic serious pathology and provide diagnostic uncertainty. They are mostly diagnosed intraoperatively or during endoscopies and scans for other reasons. We report a case of an asymptomatic patient treated for colon cancer without previous history of appendectomy. We provide long-term follow-up and aim to review the relevant literature.
    Language English
    Publishing date 2023-04-22
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad206
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Treatment of produced water using Mn oxide nanoparticales loaded on walnut shells.

    Al-Masri, M S / Amin, Y / Al-Khateeb, Y / Al-Masri, W

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2023  Volume 194, Page(s) 110692

    Abstract: ... Sorption ... ...

    Abstract Sorption of
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2023.110692
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: The Effect of Chewing Sugar-Free Gum to Improve Bowel Movement After Colorectal Surgeries in Patients With Colorectal Cancer.

    Al-Kharabsheh, Mohammad / Alwahedi, Huda / Elhamshary, Jaber / Younis, Lina / Al Masri, Mahmoud

    SAGE open nursing

    2023  Volume 9, Page(s) 23779608231170725

    Abstract: Introduction: Colorectal cancer is classified as the second most prevalent type of cancer among males and females in Jordan; approximately 1260 (10.9%) out of 11559 cases were diagnosed with colorectal cancer in 2020. According to American statistics, ... ...

    Abstract Introduction: Colorectal cancer is classified as the second most prevalent type of cancer among males and females in Jordan; approximately 1260 (10.9%) out of 11559 cases were diagnosed with colorectal cancer in 2020. According to American statistics, colorectal cancer is the third leading cause of cancer-related deaths among both males and females, as well as the second leading cause when combining both numbers .
    Objective: The current study aimed to assess the effectiveness of chewing gum in reducing postoperative ileus in patients with cancer after colorectal surgeries and evaluate the length of hospital stay (LOS) after colorectal resection, complications, and costs.
    Methods: One-hundred twenty-nine patients who underwent colorectal surgeries at a specialized cancer center in Jordan from April 2019 to May 2020 were recruited. After colorectal surgeries, patients were randomized into two groups. The control group (69 patients) received conventional postoperative care; the experimental group (60 patients) was asked to chew free sugar gum over one hour in the morning, noon, and evening until the first flatus.
    Result: The passage of the first flatus was significantly shorter in the experimental group (mean 48.02 h) than in the control group (116.45);
    Conclusion: Chewing free sugar gum after colorectal surgeries can significantly improve the recovery of bowel motion by accelerating the time to first auscultation to bowel sounds, the first passage of flatus, and reduction in the LOS, which went in agreement with many studies. However, chewing gum is considered a safe, cheap, and practical method to reduce ileus.
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2865437-7
    ISSN 2377-9608 ; 2377-9608
    ISSN (online) 2377-9608
    ISSN 2377-9608
    DOI 10.1177/23779608231170725
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Successful treatment of Gustilo type 3C open tibial fracture with a massive muscles and soft tissues wasting: A case report.

    Alsultan, Abdullah / Al Masri, Mohamad / Al-Hajjaj, Maher / Al Atrash, Muhammad / Alsultan, Mohammad

    Annals of medicine and surgery (2012)

    2022  Volume 76, Page(s) 103580

    Abstract: Introduction and importance: Gustilo-Anderson type 3 open tibial fractures are commonly accompanied by extensive damage and serious complications, especially in types 3B and 3C.: Case presentation: A 25-year-old male was transferred after motor ... ...

    Abstract Introduction and importance: Gustilo-Anderson type 3 open tibial fractures are commonly accompanied by extensive damage and serious complications, especially in types 3B and 3C.
    Case presentation: A 25-year-old male was transferred after motor vehicle accident and the emergent choice was an above-knee amputation in other two hospital. A left open distal tibial fracture (Gustilo type 3C) with a wide and contaminated soft tissues defect, that extended from the knee to the midfoot, is accompanied by wasting of the anterior compartment muscles and ruptured of the anterior tibial artery. We did irrigation and debridement and then we placed an anteriomedial external fixation system type AO with pins. A cross-leg flap and free skin grafts from the opposite limb was performed three weeks after a daily irrigation and debridement, povidon and ozone cream bandages, and antibiotics. After twelve months of follow-up, the fracture was healed and the external fixator was removed.
    Discussion/conclusion: Gustilo-Anderson type 3 open fractures remain a veritable orthopedic challenge, even for surgeons with greater experience, because of neurovascular damages, high amputation rate, and vast soft tissue injuries. The collaboration of the multidisciplinary surgical team led to preserve the limb with good result after one year. It is reasonable to judge and attempt a limb preservation even with wide open tibial fractures.
    Language English
    Publishing date 2022-04-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2022.103580
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top