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  1. Book ; Online ; E-Book: Next Generation Sequencing (NGS) Technology in DNA Analysis

    Dash, Hirak Ranjan / Elkins, Kelly M. / Al-Snan, Noora Rashid

    2024  

    Author's details Hirak Ranjan Dash, Kelly M. Elkins, and Noora Rashid Al-Snan, editors
    MeSH term(s) High-Throughput Nucleotide Sequencing ; Sequence Analysis, DNA
    Keywords High-throughput nucleotide sequencing ; DNA/Data processing
    Subject code 572.8/633
    Language English
    Size 1 online resource (614 pages)
    Edition First edition.
    Publisher Stacy Masucci
    Publishing place London, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-99380-X ; 0-323-99144-0 ; 978-0-323-99380-7 ; 978-0-323-99144-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Advancements in Forensic DNA Analysis

    Dash, Hirak Ranjan / Al-Snan, Noora Rashid / Elkins, Kelly M.

    2023  

    Author's details Dr. Hirak Ranjan Dash is an Assistant Professor of Forensic Biology and Biotechnology at National Forensic Sciences University, India. Before joining academics, he has worked as a Forensic DNA expert at Forensic Science Laboratory, Madhya Pradesh, India. He has examined more than 1000 cases by DNA fingerprinting technique. His research interests include DNA fingerprinting, Microbial forensics, microbiome analysis, Next Generation Sequencing, and mtDNA analysis. He has published more than 40 research papers in various peer-reviewed journals. He has written 10 books in various fields of Biotechnology. He is a life member and served as reviewer for various International journals. He is the pioneer worker from India on NGS based forensic DNA analysis. He is featured in the list of top 2% scientists of the world for 2021, 2022, and 2023. Dr. Kelly M. Elkins is a Professor of Chemistry at Towson University, USA, founding co-editor-in-chief of an international journal, and former Director
    Keywords DNAFingerprinting ; NGSTechnology ; ForensicDNAanalysis ; ethicalissues ; Genotypinganalyses ; DNA Fingerprinting ; NGS technology ; Forensic DNA analysis ; Ethical issues ; Genotyping analyses
    Language English
    Size 172 p.
    Edition 1
    Publisher Springer Nature Singapore
    Document type Book
    Note PDA Manuell_25
    Format 183 x 260 x 16
    ISBN 9789819961948 ; 9819961947
    Database PDA

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  3. Article ; Online: Geographical structuring and low diversity of paternal lineages in Bahrain shown by analysis of 27 Y-STRs

    Al-Snan, Noora Rashid / Messaoudi, Safia A. / Khubrani, Yahya M. / Wetton, Jon H. / Jobling, Mark A. / Bakhiet, Moiz

    Molecular genetics and genomics. 2020 Nov., v. 295, no. 6 p.1315-1324

    2020  

    Abstract: We have determined the distribution of Y-chromosomal haplotypes and predicted haplogroups in the ethnically diverse Kingdom of Bahrain, a small archipelago in the Arabian Gulf. Paternal population structure within Bahrain was investigated using the 27 Y- ... ...

    Abstract We have determined the distribution of Y-chromosomal haplotypes and predicted haplogroups in the ethnically diverse Kingdom of Bahrain, a small archipelago in the Arabian Gulf. Paternal population structure within Bahrain was investigated using the 27 Y-STRs (short tandem repeats) in the Yfiler Plus kit to generate haplotypes from 562 unrelated Bahraini males, sub-divided into four geographical regions—Northern, Capital, Southern and Muharraq. Yfiler Plus provided a significant improvement over the 17-locus Yfiler kit in discrimination capacity (from 77% to 87.5% overall), but discrimination capacity differed widely between regions from 98.4% in Muharraq to 75.2% in the Northern region, an unusually low value possibly resulting from recent rapid population expansion. Clusters of closely related male lineages were seen, with only 79.4% of donors displaying unique haplotypes and 59% of instances of shared haplotypes occurring within, rather than between, regions. Haplogroup prediction indicated diverse origins of the population with a predominance of haplogroups J2 and J1, both typical of the Arabian Peninsula, but also haplogroups such as B2 and E1b1a likely originating in Africa, and H, L and R2 likely indicative of migration from South Asia. Haplogroup frequencies differed significantly between regions, with J2 significantly more common in the Northern region compared with the Southern, possibly due to differential settlement by Baharna and Arabs. Our study shows that paternal lineage population structure can exist even over small geographical scales, and that highly discriminating genetic tools are required where rapid expansions have occurred within tightly bounded populations.
    Keywords capital ; ethnic differences ; genomics ; haplotypes ; males ; paternity ; population growth ; population structure ; prediction ; Africa ; Bahrain ; Persian Gulf ; South Asia
    Language English
    Dates of publication 2020-11
    Size p. 1315-1324.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 2044817-X
    ISSN 1617-4615
    ISSN 1617-4615
    DOI 10.1007/s00438-020-01696-4
    Database NAL-Catalogue (AGRICOLA)

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