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  1. Article: Incidence of 99Tc-MDP uptake in the external occipital protuberance in the pediatric population: the new normal?

    Muzaffar, Razi / Alassi, Amer / Mashal, Mohamed / Osman, Medhat M

    American journal of nuclear medicine and molecular imaging

    2023  Volume 13, Issue 5, Page(s) 225–229

    Abstract: Background: Children and young adults have a vast array of electronics at their fingertips. While it can provide endless hours of entertainment and education, we are also seeing a structural consequence. Children are using these devices with their head ... ...

    Abstract Background: Children and young adults have a vast array of electronics at their fingertips. While it can provide endless hours of entertainment and education, we are also seeing a structural consequence. Children are using these devices with their head tilted down with poor posture resulting in increased stress on the skull from attached structures which can lead to a bone spur (exostosis) at the external occipital protuberance (EOP). While typically painless, it can progress to necessitate surgical intervention.
    Objectives: The purpose of this study is to understand the prevalence of exostosis at the EOP and how the finding can affect the nuclear medicine bone scan.
    Materials and methods: 43 pediatric patients who underwent a whole-body bone scan over a period of 1 year were included in the study (10-19 years old). Images were reviewed by 2 board-certified Nuclear Medicine physicians to assess for uptake midline in the occipital skull. Suspected cases were followed up with all available clinical and radiographic reports and images.
    Results: Bone scan demonstrated an occipital focus of uptake in 7 (16%) of the 43 patients (5 males and 2 females with a mean age of 15 years; range 10-19). Of these, 5/7 (71%) were confirmed by additional imaging.
    Conclusion: The rapidly advancing technology is leading to increased screen time in children and young adults. Our study shows that 16% of the pediatric population imaged at our facility between the ages of 10-19 years have signs of exostosis at the EOP. It is particularly important for clinicians to be aware of this entity when reading bone scans to avoid false positive interpretations.
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2623515-8
    ISSN 2160-8407
    ISSN 2160-8407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Transforming Neurology and Psychiatry: Organ-specific PET Instrumentation and Clinical Applications.

    Taha, Ahmed / Alassi, Amer / Gjedde, Albert / Wong, Dean F

    PET clinics

    2023  Volume 19, Issue 1, Page(s) 95–103

    Abstract: PET technology has immense potential for furthering understanding of the brain and associated disorders, including advancements in high-resolution tomographs and hybrid imaging modalities. Novel radiotracers targeting specific neurotransmitter systems ... ...

    Abstract PET technology has immense potential for furthering understanding of the brain and associated disorders, including advancements in high-resolution tomographs and hybrid imaging modalities. Novel radiotracers targeting specific neurotransmitter systems and molecular markers provide opportunities to unveil intricate mechanisms underlying neurologic and psychiatric conditions. As PET imaging techniques and analysis methods continue to be refined, the field is poised to make significant contributions to personalized medicine for more targeted and effective interventions. PET instrumentation has advanced the fields of neurology and psychiatry, providing insights into pathophysiology and development of effective treatments.
    MeSH term(s) Humans ; Positron-Emission Tomography/methods ; Neurology ; Brain/diagnostic imaging ; Tomography, X-Ray Computed ; Psychiatry
    Language English
    Publishing date 2023-10-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2764575-7
    ISSN 1879-9809 ; 1556-8598
    ISSN (online) 1879-9809
    ISSN 1556-8598
    DOI 10.1016/j.cpet.2023.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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