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  1. Article ; Conference proceedings: Extended Endoscopic Endonasal Approaches for the Skull Base: the Rate of Complications

    Alqurashi, Ashwag / Alatar, Abdullah / Ajlan, Abdulrazaq

    Journal of Neurological Surgery Part B: Skull Base

    2021  Volume 82, Issue S 02

    Event/congress Special Virtual Symposium of the North American Skull Base Society, Online, 2021-02-13
    Language English
    Publishing date 2021-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0041-1725459
    Database Thieme publisher's database

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  2. Article ; Online: Micro-morpho-anatomical transitions at various stages of in vitro development of Crinum malabaricum Lekhak and Yadav: A critically endangered medicinal plant.

    Mani, M / Mathiyazhagan, C / Dey, A / Faisal, M / Alatar, A A / Alok, A / Shekhawat, M S

    Plant biology (Stuttgart, Germany)

    2022  

    Abstract: Crinum malabaricum Lekhak & Yadav is a recently discovered and critically endangered aquatic bulbous plant of the family Amaryllidaceae. It gained attention as a wild source of the acetylcholinesterase inhibiting alkaloid 'galanthamine' used to treat ... ...

    Abstract Crinum malabaricum Lekhak & Yadav is a recently discovered and critically endangered aquatic bulbous plant of the family Amaryllidaceae. It gained attention as a wild source of the acetylcholinesterase inhibiting alkaloid 'galanthamine' used to treat Alzheimer and Parkinson diseases. The bulbs of this plant contain the highest amount of galanthamine among Crinum species. In vitro regeneration systems were developed to produce quality uniform plantlets of C. malabaricum. Bright field light microscopy was used to analyse micro-morpho-anatomical developments taking place in the leaves and roots during in vitro, ex vitro and in vivo transitions of plantlets. Leaves and roots of plants raised in vitro possessed a higher degree of microscopic structural anomalies, such as underdeveloped epicuticular wax deposition, immature and non-functional stomata, more aquiferous parenchyma with a reduced lumen. Roots developed in vitro were characterized by extremely large, uneven cortical cells and reduced intercellular spaces. The vascular tissues were under-developed and only primary vascular tissues were observed. As a result of ex vitro acclimation, there was a significant acceleration in the improvement of tissue systems in leaves and roots. Such plantlets can tolerate elevated temperatures and light under in vivo conditions. Thus, the microscopic evaluation of the structural trajectory in different stages of plantlet development provides an understanding of the acclimation process and structural adaptations, which could help enhance survival of in vitro raised plantlets under ex vitro and in vivo conditions.
    Language English
    Publishing date 2022-08-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1464075-2
    ISSN 1438-8677 ; 1435-8603
    ISSN (online) 1438-8677
    ISSN 1435-8603
    DOI 10.1111/plb.13464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Expanded transnasal approaches to the skull base in the Middle East: Where do we stand?

    Alsaleh, Saad / Albakr, Abdulrahman / Alromaih, Saud / Alatar, Abdullah / Alroqi, Ahmad Salman / Ajlan, Abdulrazag

    Annals of Saudi medicine

    2020  Volume 40, Issue 2, Page(s) 94–104

    Abstract: Background: Endoscopic transnasal surgery has gained rapid global acceptance over the last two decades. The growing literature and understanding of anterior skull base endoscopic anatomy, in addition to new dedicated endoscopic instruments and tools, ... ...

    Abstract Background: Endoscopic transnasal surgery has gained rapid global acceptance over the last two decades. The growing literature and understanding of anterior skull base endoscopic anatomy, in addition to new dedicated endoscopic instruments and tools, have helped to expand the use of the transnasal route in skull base surgery.
    Objective: Report our early experience in expanded endoscopic transnasal surgery (EETS) and approach to skull base neoplasms.
    Design: Descriptive, retrospective case series.
    Setting: Major tertiary care center.
    Patients and methods: A retrospective case review was conducted at King Saud University Medical City between December 2014 and August 2019. Cases with skull base neoplasms that underwent EETS were included. EETS was defined as endoscopic surgical exposure that extended beyond the sellar margins (prechiasmatic sulcus superiorly, clival recess inferiorly, cavernous carotid lines laterally). Routine transsphenoidal pituitary neoplasms, neoplasms of sinonasal origin and meningoencephaloceles were excluded.
    Main outcome measures: Preoperative clinical assessment, imaging results, surgical approach, and hospital course were all retrieved from the patient electronic charts. Clinical follow-up, perioperative complications, and gross residual tumor rates were documented and reviewed.
    Sample size and characteristics: 45 cases of EETS, 13 males and 32 females with mean age of 39.0 (17.7) years (range 2-70 years).
    Results: The series comprised a wide range of pathologies, including giant pituitary adenoma (8 cases), meningioma (23 cases), craniopharyngioma (4 cases), chordoma (4 cases), optic pathway glioma (2 cases), epidermoid neoplasms (2 cases), astrocytoma (1 case), and teratoma (1 case). For the entire series, gross total resection was achieved in 25/45 operations (55.5%). Postoperative cerebrospinal fluid leak was the most common complication observed in 9 patients (20%) which were all managed endoscopically. Major vascular complications occurred in 2 patients (4.4%) and are described. Other complications are outlined as well. No mortality was observed.
    Conclusions: EETS to the skull base can be done with results comparable to traditional approaches. More work is needed to expand our experience, improve outcomes, and educate the public and medical community in our region about the usefulness of this approach.
    Limitations: Sample size and study design.
    Conflict of interest: None.
    MeSH term(s) Adenoma/diagnostic imaging ; Adenoma/surgery ; Adolescent ; Adult ; Aged ; Astrocytoma/diagnostic imaging ; Astrocytoma/surgery ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/surgery ; Carotid Artery Injuries/epidemiology ; Carotid Artery Injuries/surgery ; Carotid Artery, Internal ; Cerebral Arteries/injuries ; Cerebral Ventriculitis/epidemiology ; Cerebrospinal Fluid Leak/epidemiology ; Cerebrospinal Fluid Leak/surgery ; Child ; Child, Preschool ; Chordoma/diagnostic imaging ; Chordoma/surgery ; Craniopharyngioma/diagnostic imaging ; Craniopharyngioma/surgery ; Diabetes Insipidus/epidemiology ; Epidermal Cyst/diagnostic imaging ; Epidermal Cyst/surgery ; Female ; Humans ; Intraoperative Complications/epidemiology ; Intraoperative Complications/surgery ; Male ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/surgery ; Meningioma/diagnostic imaging ; Meningioma/surgery ; Meningitis/epidemiology ; Middle Aged ; Nasal Cavity ; Natural Orifice Endoscopic Surgery/methods ; Neuroendoscopy/methods ; Optic Nerve Glioma/diagnostic imaging ; Optic Nerve Glioma/surgery ; Pituitary Neoplasms/diagnostic imaging ; Pituitary Neoplasms/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Reoperation ; Saudi Arabia ; Skull Base Neoplasms/diagnostic imaging ; Skull Base Neoplasms/surgery ; Surgical Wound Infection/epidemiology ; Teratoma/diagnostic imaging ; Teratoma/surgery ; Vascular System Injuries/epidemiology ; Vascular System Injuries/surgery ; Young Adult
    Language English
    Publishing date 2020-04-02
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 639014-6
    ISSN 0975-4466 ; 0256-4947
    ISSN (online) 0975-4466
    ISSN 0256-4947
    DOI 10.5144/0256-4947.2020.94
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Conference proceedings: Postoperative CNS Infections after Extended Transnasal Skull Base Surgery

    Alatar, Abdullah / Alqurashi, Ashwag / Ajlan, Abdulrazag

    Journal of Neurological Surgery Part B: Skull Base

    2019  Volume 80, Issue S 01

    Event/congress 29th Annual Meeting North American Skull Base Society, Hilton Orlando Bonnet Creek Orlando, Florida, 2019-02-15
    Language English
    Publishing date 2019-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0039-1679482
    Database Thieme publisher's database

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  5. Article: Inoculation with arbuscular mycorrhizal fungi alleviates harmful effects of drought stress on damask rose.

    Abdel-Salam, Eslam / Alatar, Abdulrahman / El-Sheikh, Mohamed A

    Saudi journal of biological sciences

    2017  Volume 25, Issue 8, Page(s) 1772–1780

    Abstract: This study was conducted to examine the role of arbuscular mycorrhiza fungi (AMF) in alleviating the adverse effects of drought stress on damask rose ( ...

    Abstract This study was conducted to examine the role of arbuscular mycorrhiza fungi (AMF) in alleviating the adverse effects of drought stress on damask rose (
    Language English
    Publishing date 2017-10-12
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2017.10.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The battle of two ions: Ca

    Köster, P / Wallrad, L / Edel, K H / Faisal, M / Alatar, A A / Kudla, J

    Plant biology (Stuttgart, Germany)

    2018  Volume 21 Suppl 1, Page(s) 39–48

    Abstract: Soil salinity adversely affects plant growth, crop yield and the composition of ecosystems. Salinity stress impacts plants by combined effects of ... ...

    Abstract Soil salinity adversely affects plant growth, crop yield and the composition of ecosystems. Salinity stress impacts plants by combined effects of Na
    MeSH term(s) Calcium Signaling/drug effects ; Ions ; Plant Growth Regulators/metabolism ; Plant Transpiration/drug effects ; Salinity ; Sodium/pharmacology ; Stress, Physiological/drug effects
    Chemical Substances Ions ; Plant Growth Regulators ; Sodium (9NEZ333N27)
    Language English
    Publishing date 2018-03-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1464075-2
    ISSN 1438-8677 ; 1435-8603
    ISSN (online) 1438-8677
    ISSN 1435-8603
    DOI 10.1111/plb.12704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Calcium Signaling during Salt Stress and in the Regulation of Ion Homeostasis.

    Manishankar, P / Wang, N / Köster, P / Alatar, A A / Kudla, J

    Journal of experimental botany

    2018  

    Abstract: Soil composition largely defines the living conditions of plants and represents one of their most relevant, dynamic and complex environmental cues. The effective concentrations of many either tolerated or essential ions and compounds in the soil usually ... ...

    Abstract Soil composition largely defines the living conditions of plants and represents one of their most relevant, dynamic and complex environmental cues. The effective concentrations of many either tolerated or essential ions and compounds in the soil usually differ from the optimum that would be most suitable for plants. In this regard, salinity - caused by excess of NaCl - represents a widespread adverse growth condition but also shortage of ions like K+, NO3- and Fe2+ restrains plant growth. During the past years many components and mechanisms that function in the sensing and establishment of ion homeostasis have been identified and characterized. Here, we reflect on recent insights that extended our understanding of components and mechanisms, which govern and fine-tune plant salt stress tolerance and ion homeostasis. We put special emphasis on mechanisms that allow for interconnection of the salt overly sensitivity pathway with plant development and discuss newly emerging functions of Ca2+ signaling in salinity tolerance. Moreover, we review and discuss accumulating evidence for a central and unifying role of Ca2+ signaling and Ca2+ dependent protein phosphorylation in regulating sensing, uptake, transport and storage processes of various ions. Finally, based on this cross-field inventory, we deduce emerging concepts and arising questions for future research.
    Language English
    Publishing date 2018-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2976-2
    ISSN 1460-2431 ; 0022-0957
    ISSN (online) 1460-2431
    ISSN 0022-0957
    DOI 10.1093/jxb/ery201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Cryopreservation of grapevine shoot tips from in vitro plants using droplet vitrification and v cryo-plate techniques

    Bettoni, J. C. / Pathirana, R. / Bonnart, R. / Shepherd, A. / Volk, G. / Faisal, M. / Alatar, A. A. (Eds.)

    2019  , Page(s) 469–482

    Abstract: conservation; genetic resources; germplasm; tissue culture; Vitis. ...

    Institution Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States
    Event/congress Synthetic Seeds: Germplasm Regeneration, Preservation and Prospects
    Abstract conservation; genetic resources; germplasm; tissue culture; Vitis.
    Language English
    Document type Book
    Database Viticulture and Oenology Abstracts

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  9. Article: Detection of Molecular and Phytochemical Variations in Tamilnadu Landraces of Gymnema sylvestre Genotype: An Important Anti-Diabetic Plant

    Jinu, U. / Thiayagarajan, M. / Javed, S. / Alatar, A. A. / Venkatachalam, P.

    Journal of agricultural science and technology

    2019  Volume 21, Issue 6, Page(s) 14

    Language English
    Document type Article
    ZDB-ID 2158975-6
    ISSN 1680-7073
    Database Current Contents Nutrition, Environment, Agriculture

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  10. Article: Vegetation analysis of Wadi Al-Jufair, a hyper-arid region in Najd, Saudi Arabia.

    Alatar, Abdulrahman / El-Sheikh, Mohamed A / Thomas, Jacob

    publication RETRACTED

    Saudi journal of biological sciences

    2012  Volume 19, Issue 3, Page(s) 357–368

    Abstract: Wadi Al-Jufair, a tributary of Wadi Nisah, is one of the important wadis of Najd region (Saudi Arabia) sheltering a rich diversity of higher plants. The study area is extended into approximately 15 km(2) encompassing the commonest geomorphological ... ...

    Abstract Wadi Al-Jufair, a tributary of Wadi Nisah, is one of the important wadis of Najd region (Saudi Arabia) sheltering a rich diversity of higher plants. The study area is extended into approximately 15 km(2) encompassing the commonest geomorphological features encountered in desert wadis. The wadi supports several rare plants, including Maerua crassifolia Forssk., a regionally endangered tree, and Acacia oerfota (Forssk.) Schweinf., a rare shrub with restricted distribution. The present study aims to analyze the vegetation of wadi Al-Jufair and propose its designation as an important plant reserve. The vegetation type is fundamentally of chamaephytic nature with some phanerophytes, and distinguished into associations where the dominant perennial species give the permanent character of plant cover in each habitat. Four vegetation groups were identified with the application of TWINSPAN, DCA and CCA programs and named after the characteristic species as follows: Lycium shawii; A. oerfota; Acacia raddiana-Rhazya stricta and Artemisia monosperma. These plant associations demonstrate significant variation in soil texture, moisture, organic matter, pH, EC, and minerals of Wadi Al-Jufair.
    Language English
    Publishing date 2012-05-17
    Publishing country Saudi Arabia
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2012.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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