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  1. Article ; Online: Similar effectiveness of the inactivated vaccine BBIBP-CorV (Sinopharm) and the mRNA vaccine BNT162b2 (Pfizer-BioNTech) against COVID-19 related hospitalizations during the Delta outbreak in the UAE.

    Mousa, Mira / Albreiki, Mohammed / Alshehhi, Fatima / AlShamsi, Safiya / Marzouqi, Nada Al / Alawadi, Tayba / Alrand, Hussain / Alsafar, Habiba / Fikri, Asma

    Journal of travel medicine

    2022  Volume 29, Issue 6

    MeSH term(s) BNT162 Vaccine ; COVID-19/prevention & control ; Disease Outbreaks/prevention & control ; Hospitalization ; Humans ; Vaccines, Inactivated ; Vaccines, Synthetic ; mRNA Vaccines
    Chemical Substances Vaccines, Inactivated ; Vaccines, Synthetic ; mRNA Vaccines ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2022-03-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Risk of hospitalization and vaccine effectiveness among COVID-19 patients in the UAE during the Delta and Omicron outbreaks.

    Albreiki, Mohammed / Mousa, Mira / Azman, Syafiq Kamarul / Vurivi, Hema / Alhalwachi, Zainab / Alshehhi, Fatima / AlShamsi, Safiya / Marzouqi, Nada Al / Alawadi, Tayba / Alrand, Hussain / Oulhaj, Abderrahim / Fikri, Asma / Alsafar, Habiba

    Frontiers in immunology

    2023  Volume 14, Page(s) 1049393

    Abstract: Introduction: A rapid increase in COVID-19 cases due to the spread of the Delta and Omicron variants in vaccinated populations has raised concerns about the hospitalization risk associated with, and the effectiveness of, COVID-19 vaccines.: Method: ... ...

    Abstract Introduction: A rapid increase in COVID-19 cases due to the spread of the Delta and Omicron variants in vaccinated populations has raised concerns about the hospitalization risk associated with, and the effectiveness of, COVID-19 vaccines.
    Method: This case-control study aims to determine the hospitalization risk associated with the inactivated BBIBP-CorV (Sinopharm) and mRNA BNT162b2 (Pfizer-BionTech) vaccines, and their effectiveness reducing the rate of hospital admission between 28 May 2021 and 13 January 2022, during the Delta and Omicron outbreaks. The estimation of vaccine effectiveness of 4,618 samples was based on the number of patients hospitalized at different vaccination statuses, adjusted for confounding variables.
    Results: Hospitalization risk increases in patients affected with the Omicron variant if patients are aged ≤ 18 years (OR 6.41, 95% CI 2.90 to 14.17; p < 0.001), and in patients affected with the Delta variant if they are aged > 45 years (OR 3.41, 95% CI 2.21 to 5.50; p < 0.001). Vaccine effectiveness reducing the rate of hospital admission for fully vaccinated participants infected with the Delta and Omicron variants was similar for both the BBIBP-CorV (94%, 95% CI 90% to 97%; 90%, 95% CI 74% to 96%) and BNT162b2 vaccines (95%, 95% CI 61% to 99.3%; 94%, 95% CI 53% to 99%), respectively.
    Discussion: The BBIBP-CorV and BNT162b2 vaccines utilized in the UAE vaccination program were highly effective in reducing the rate of COVID-19-related hospitalization during the Delta and Omicron outbreaks, and further effort must be taken to achieve high vaccine coverage rates in children and adolescents in the global context to reduce the hospitalization risk associated with COVID-19 on an international scale.
    MeSH term(s) Adolescent ; Child ; Humans ; COVID-19 Vaccines/therapeutic use ; COVID-19/epidemiology ; COVID-19/prevention & control ; Vaccine Efficacy ; BNT162 Vaccine ; Case-Control Studies ; SARS-CoV-2 ; Disease Outbreaks ; Hospitalization
    Chemical Substances BIBP COVID-19 vaccine ; COVID-19 Vaccines ; BNT162 Vaccine
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1049393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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