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  1. AU="Albahrani, Salma"
  2. AU="Endres, R"
  3. AU="Lahiri, Thomas"
  4. AU=Clift Ashley Kieran
  5. AU="Lebrero, María Eugenia"
  6. AU="Beukenhorst, Anna L"
  7. AU="Rubel, Diana"
  8. AU="Stanford, Janet L"
  9. AU=da Costa Simone M
  10. AU="Zhu, Yuan-Ting"
  11. AU="Fleet, Richard"
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  1. Article: Bilateral adrenal hemorrhage in antiphospholipid syndrome. Anticoagulation for the treatment of hemorrhage.

    Aldaajani, Hana / Albahrani, Salma / Saleh, Khalid / Alghanim, Khawla

    Saudi medical journal

    2018  Volume 39, Issue 8, Page(s) 829–833

    Abstract: A 43-year-old man with Hashimoto's thyroiditis and previous thromboembolic events treated with warfarin for 6 months, presented with right flank pain accompanied with vomiting, dizziness, and altered mental status 2 weeks after discontinuation of ... ...

    Abstract A 43-year-old man with Hashimoto's thyroiditis and previous thromboembolic events treated with warfarin for 6 months, presented with right flank pain accompanied with vomiting, dizziness, and altered mental status 2 weeks after discontinuation of warfarin. His clinical examination findings were unremarkable. Routine blood work showed lymphopenia, thrombocytopenia, and hypoosmolar hyponatremia. Random serum cortisol level was low (14 nmol/L). Computed tomography scan of the abdomen revealed bilateral bulky heterogeneous suprarenal gland surrounded by fat stranding representing adrenal hemorrhage. He was treated for acute adrenal crisis and subsequently started on hydrocortisone and fludrocortisone, with significant clinical improvement. His diagnosis was secondary antiphospholipid syndrome (APS) to systemic lupus erythematosus (SLE). Bilateral adrenal thrombosis lead to hemorrhage in the adrenals as a paradoxical effect after warfarin cessation and primarily caused by APS. Bilateral adrenal bleeding should lead to the suspicion of thrombophilic disorders, such as APS, with cautious anticoagulation as the treatment of choice.
    MeSH term(s) Adrenal Gland Diseases/diagnostic imaging ; Adrenal Gland Diseases/drug therapy ; Adrenal Gland Diseases/etiology ; Adult ; Anticoagulants/therapeutic use ; Antiphospholipid Syndrome/complications ; Hashimoto Disease/complications ; Hemorrhage/diagnostic imaging ; Hemorrhage/drug therapy ; Hemorrhage/etiology ; Humans ; Lupus Erythematosus, Systemic/complications ; Male ; Tomography, X-Ray Computed
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2018-09-23
    Publishing country Saudi Arabia
    Document type Case Reports ; Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    DOI 10.15537/smj.2018.8.22437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2330: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
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  2. Article: Perinatal sacroiliitis diagnostic challenges.

    Kheder, Emam M / Sharahili, Hussain H / Albahrani, Salma Y / Alfarhan, Abdullah M / Alquraynis, Abdulrahman M / Maitigue, Mahmoud B / Al Wehaibi, Ahmed M

    SAGE open medical case reports

    2021  Volume 9, Page(s) 2050313X211052442

    Abstract: Lumbo-pelvic pain is a common and non-specific problem during pregnancy and postpartum. Although perinatal pyogenic sacroiliitis is uncommon during this time, it might be difficult to distinguish from reactive sacroiliitis in women who are experiencing ... ...

    Abstract Lumbo-pelvic pain is a common and non-specific problem during pregnancy and postpartum. Although perinatal pyogenic sacroiliitis is uncommon during this time, it might be difficult to distinguish from reactive sacroiliitis in women who are experiencing significant lower back and pelvic girdle pain, as the symptoms and signs are not clear and the tests are not definitive. A 34-year-old primigravida went to the emergency department with severe lower back pain radiating to the right gluteal region and down to the back of the right thigh. This pain began 12 days prior to her presentation and eventually worsened to the point that she could not stand or walk. Her vital signs were within normal ranges, and she was experiencing a fever. Apart from a slight widening of the symphysis pubis, her pelvic and lumbo-sacral pain X-rays revealed no important findings. With the clinical impression of right lumbo-pelvic pain, the patient was admitted for pain management and further inquiries. Despite the fact that the antibiotherapy was prescribed to treat a urinary tract infection, the significant recovery of the patient's symptoms, even in the absence of a definitive culture of aspirate from the right sacroiliac joint, supported the diagnosis of pyogenic sacroiliitis.
    Language English
    Publishing date 2021-10-12
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X211052442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy of tocilizumab in patients with severe COVID-19: Survival and clinical outcomes.

    Al-Baadani, Abeer / Eltayeb, Nazik / Alsufyani, Eid / Albahrani, Salma / Basheri, Shareefah / Albayat, Hawra / Batubara, Enas / Ballool, Sulafa / Al Assiri, Ayed / Faqihi, Fahad / Musa, Ali B / Robert, Asirvatham A / Alsherbeeni, Nisreen / Elzein, Fatehi

    Journal of infection and public health

    2021  Volume 14, Issue 8, Page(s) 1021–1027

    Abstract: Background: SARS-CoV-2 is associated with a severe inflammatory response contributing to respiratory and systemic manifestations, morbidity, and mortality in patients with coronavirus disease 2019 (COVID-19).: Methods: Tocilizumab (TCZ) efficacy on ... ...

    Abstract Background: SARS-CoV-2 is associated with a severe inflammatory response contributing to respiratory and systemic manifestations, morbidity, and mortality in patients with coronavirus disease 2019 (COVID-19).
    Methods: Tocilizumab (TCZ) efficacy on mortality and length of hospital stay was retrospectively evaluated in patients who received TCZ and compared with that in controls with a similar severity of COVID-19. The primary endpoint was survival probability on day 28. The secondary endpoints included survival at day 14 and length of hospital stay.
    Results: Of the 148 patients included in the study, 62 received TCZ and standard of care, whereas 86 served as a control group and received only standard of care. The two groups were similar, although TCZ-treated patients were more likely to exhibit hypertension (46.7% vs. 29.8%), chronic kidney disease (14.5% vs. 1.1%), and high Charlson score (1.18 vs. 1.00; p = 0.006) and less likely to receive corticosteroid treatment (48.5% vs. 93.0%). TCZ was associated with lower mortality on both day 28 (16.1% vs. 37.2%, p = 0.004) and day 14 (9.7% vs. 24.4%, p = 0.022). The hospital stay was longer in the TCZ-treated than in the control group (15.6 ± 7.59 vs.17.7 ± 7.8 days, p = 0.103). Ten patients (16.0%) in the TCZ-treated group developed infections.
    Conclusion: TCZ was associated with a lower likelihood of death despite resulting in higher infection rates and a non-significant longer hospital stay.
    MeSH term(s) Antibodies, Monoclonal, Humanized ; Humans ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; COVID-19 Drug Treatment
    Chemical Substances Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2021-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2021.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The impact of obesity on hospitalized patients with COVID-19 infection in the Eastern Province of Saudi Arabia.

    AlKhafaji, Dania / Al Argan, Reem / Albahrani, Salma / Al Elq, Abdulmohsen / Albaker, Waleed / Al-Hariri, Mohammed / Alwaheed, Abrar / Alqatari, Safi / Alzaki, Alaa / Alsaid, Abir / Alwazzeh, Marwan / AlRubaish, Fatimah / Alelq, Zainab / Alsaif, Tariq / Zeeshan, Mohammad / Alzahrani, Nada / Alhusil, Abdulrahman / Gasmelseed, Batool / Zainuddin, Fatma /
    Alhwiesh, Amani / Alrubaish, Nafie

    Journal of medicine and life

    2022  Volume 15, Issue 3, Page(s) 425–432

    Abstract: This study aimed to assess the association of obesity with the severity and outcome of COVID-19 infection. A retrospective observational study was performed from March to September 2020 in Saudi Arabia. Baseline and laboratory data were collected from ... ...

    Abstract This study aimed to assess the association of obesity with the severity and outcome of COVID-19 infection. A retrospective observational study was performed from March to September 2020 in Saudi Arabia. Baseline and laboratory data were collected from the inpatient health record system. The cohort was divided into three groups based on body mass index. Following this, the severity and outcome of COVID-19 disease were analyzed between the three groups. Of the 502 COVID-19 cases included, 244 (48.5%) were obese. Obesity was significantly associated with severe (53.5%) or critical (28%) COVID-19 infection (P<0.001) and a higher need for ICU admission (35.8%, P=0.034). Multivariate analysis showed that overweight/obesity was an independent risk factor of severe (P<0.001) as well as critical COVID-19 infection (P=0.026, respectively) and a predictor of a higher risk of ICU admission (P=0.012). Class I obesity was associated with severe-critical COVID-19 disease (33.6%, P=0.042) compared to other obesity classes. Obesity is an independent risk factor for severe-critical COVID-19 infection and a higher risk of ICU admission. Clinicians should give special attention to such populations and prioritize vaccination programs to improve outcomes.
    MeSH term(s) Body Mass Index ; COVID-19/epidemiology ; Hospitalization ; Humans ; Obesity/complications ; Obesity/epidemiology ; Retrospective Studies ; Saudi Arabia/epidemiology
    Language English
    Publishing date 2022-03-31
    Publishing country Romania
    Document type Journal Article ; Observational Study
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3117 ; 1844-3109
    ISSN (online) 1844-3117
    ISSN 1844-3117 ; 1844-3109
    DOI 10.25122/jml-2022-0033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk factors for surgical site infection after kidney and pancreas transplantation.

    Natori, Yoichiro / Albahrani, Salma / Alabdulla, Mohammed / Vu, James / Chow, Edwin / Husain, Shahid / Kumar, Deepali / Humar, Atul / Schiff, Jeffrey / Cattral, Mark / Rotstein, Coleman

    Infection control and hospital epidemiology

    2018  Volume 39, Issue 9, Page(s) 1042–1048

    Abstract: Objective: To evaluate the incidence of surgical site infection (SSI) in a cohort of pancreas transplant recipients and assess predisposing risk factors for SSI DESIGN: Retrospective cohort study SETTING: Single transplant center in ... ...

    Abstract Objective: To evaluate the incidence of surgical site infection (SSI) in a cohort of pancreas transplant recipients and assess predisposing risk factors for SSI DESIGN: Retrospective cohort study SETTING: Single transplant center in CanadaPatientsPatients who underwent any simultaneous pancreas and kidney (SPK) or pancreas after kidney (PAK) transplant procedures between January 2000 and December 2015 METHODS: In this retrospective cohort evaluation of SPK or PAK recipients, we assessed the incidence of SSI and risk factors associated with superficial, deep, and organ/space SSI. Multivariate logistic regression was used to identify independent risk factors for SSI in SPK and PAK recipients.
    Results: In total, 445 adult transplant recipients were enrolled. The median age of these patients was 51 years (range, 19-71 years), and 64.9% were men. SSIs were documented in 108 patients (24.3%). Organ/space SSIs predominated (59 patients, 54.6%), followed by superficial SSIs (47 patients, 43.5%) and deep SSIs (3 patients, 2.8%). Factors predictive of SSIs in the multivariate analysis were cold pancreas ischemic time (odds ratio [OR], 1.002; P=.019) and SPK transplant (compared to PAK transplant recipients; OR, 2.38; P=.038). Patients with SSIs developed graft loss more frequently (OR, 16.99; P<.001).
    Conclusions: Organ/space SSIs remain a serious and common complication after SPK and PAK. Prolonged cold ischemic time and SPK transplant were the risk factors predictive of SSIs. Appropriate perioperative prophylaxis in high-risk patients targeting the potential pathogens producing SSIs in kidney and/or pancreas transplant recipients and a reduction in cold ischemia may prove beneficial in reducing these SSIs.
    MeSH term(s) Adult ; Aged ; Canada/epidemiology ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Female ; Humans ; Incidence ; Kidney Transplantation/adverse effects ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Pancreas Transplantation/adverse effects ; Retrospective Studies ; Risk Factors ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/microbiology ; Young Adult
    Language English
    Publishing date 2018-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2018.148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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