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  1. Article ; Online: Transmission of Omicron (B.1.1.529) - SARS-CoV-2 Variant of Concern in a designated quarantine hotel for travelers

    Shuk-Ching Wong / Albert Ka-Wing Au / Hong Chen / Lithia Lai-Ha Yuen / Xin Li / David Christopher Lung / Allen Wing-Ho Chu / Jonathan Daniel Ip / Wan-Mui Chan / Hoi-Wah Tsoi / Kelvin Kai-Wang To / Kwok-Yung Yuen / Vincent Chi-Chung Cheng

    The Lancet Regional Health. Western Pacific, Vol 18, Iss , Pp 100360- (2022)

    a challenge of elimination strategy of COVID-19

    2022  

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Contribution of low population immunity to the severe Omicron BA.2 outbreak in Hong Kong

    Lin-Lei Chen / Syed Muhammad Umer Abdullah / Wan-Mui Chan / Brian Pui-Chun Chan / Jonathan Daniel Ip / Allen Wing-Ho Chu / Lu Lu / Xiaojuan Zhang / Yan Zhao / Vivien Wai-Man Chuang / Albert Ka-Wing Au / Vincent Chi-Chung Cheng / Siddharth Sridhar / Kwok-Yung Yuen / Ivan Fan-Ngai Hung / Kwok-Hung Chan / Kelvin Kai-Wang To

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 10

    Abstract: Hong Kong experienced a severe wave of SARS-CoV-2 in early 2022. Here, the authors use genomic and serosurveillance data and show that this wave was dominated by the Omicron BA.2 sublineage, and that low protective immunity, particularly in older age ... ...

    Abstract Hong Kong experienced a severe wave of SARS-CoV-2 in early 2022. Here, the authors use genomic and serosurveillance data and show that this wave was dominated by the Omicron BA.2 sublineage, and that low protective immunity, particularly in older age groups, contributed to its severity.
    Keywords Science ; Q
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Complementation of contact tracing by mass testing for successful containment of beta COVID-19 variant (SARS-CoV-2 VOC B.1.351) epidemic in Hong Kong

    Vincent Chi-Chung Cheng / Gilman Kit-Hang Siu / Shuk-Ching Wong / Albert Ka-Wing Au / Cecilia Suk-Fun Ng / Hong Chen / Xin Li / Lam-Kwong Lee / Jake Siu-Lun Leung / Kelvin Keru Lu / Hazel Wing-Hei Lo / Evelyn Yin-Kwan Wong / Shik Luk / Bosco Hoi-Shiu Lam / Wing-Kin To / Rodney Allan Lee / David Christopher Lung / Mike Yat-Wah Kwan / Herman Tse /
    Shuk-Kwan Chuang / Kelvin Kai-Wang To / Kwok-Yung Yuen

    The Lancet Regional Health. Western Pacific, Vol 17, Iss , Pp 100281- (2021)

    2021  

    Abstract: Background: Global dissemination of SARS-CoV-2 Variants of Concern (VOCs) remains a concern. The aim of this study is to describe how mass testing and phylogenetic analysis successfully prevented local transmission of SARS-CoV-2 VOC in a densely ... ...

    Abstract Background: Global dissemination of SARS-CoV-2 Variants of Concern (VOCs) remains a concern. The aim of this study is to describe how mass testing and phylogenetic analysis successfully prevented local transmission of SARS-CoV-2 VOC in a densely populated city with low herd immunity for COVID-19. Methods: In this descriptive study, we conducted contact tracing, quarantine, and mass testing of the potentially exposed contacts with the index case. Epidemiological investigation and phylogeographic analysis were performed. Findings: Among 11,818 laboratory confirmed cases of COVID-19 diagnosed till 13th May 2021 in Hong Kong, SARS-CoV-2 VOCs were found in 271 (2.3%) cases. Except for 10 locally acquired secondary cases, all SARS-CoV-2 VOCs were imported or acquired in quarantine hotels. The index case of this SARS-CoV-2 VOC B.1.351 epidemic, an inbound traveler with asymptomatic infection, was diagnosed 9 days after completing 21 days of quarantine. Contact tracing of 163 contacts in household, hotel, and residential building only revealed 1 (0.6%) secondary case. A symptomatic foreign domestic helper (FDH) without apparent epidemiological link but infected by virus with identical genome sequence was subsequently confirmed. Mass testing of 0.34 million FDHs identified two more cases which were phylogenetically linked. A total of 10 secondary cases were identified that were related to two household gatherings. The clinical attack rate of household close contact was significantly higher than non-household exposure during quarantine (7/25, 28% vs 0/2051, 0%; p<0.001). Interpretation: The rising epidemic of SARS-CoV-2 VOC transmission could be successfully controlled by contact tracing, quarantine, and rapid genome sequencing complemented by mass testing. Funding: Health and Medical Research Fund Commissioned Research on Control of Infectious Disease (see acknowledgments for full list).
    Keywords SARS-CoV-2 ; Variants of Concern ; Contact tracing ; Mass testing ; Phylogenetic analysis ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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