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  1. Book ; Thesis: In vivo optische Kohärenztomographie der gesunden humanen Mundschleimhaut

    Albrecht, Marius / Walther, Julia / Lauer, Günter

    2022  

    Institution Technische Universität Dresden / Arbeitsbereich Medizinische Physik und Biomedizinische Technik
    Author's details von Marius Albrecht aus Aschaffenburg ; Arbeitsbereich Medizinische Physik und Biomedizinische Technik [Dresden]
    Language German
    Size XII, 196 Seiten, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2023
    HBZ-ID HT030070596
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The Monomer-Dimer Equilibrium of Triscatechol Titanium(IV)-Based Hierarchical Helicates as a Tool for the Development of Molecular Balances and Molecular Switches.

    Albrecht, Markus

    Accounts of chemical research

    2023  Volume 56, Issue 22, Page(s) 3271–3281

    Abstract: ConspectusHierarchical helicates are formed by noncovalent connection of two or more monomeric metal complex units, e.g., by bridging metal cations. A unique kind of hierarchical helicate is obtained from 3-carbonyl substituted catechol ligands with ... ...

    Abstract ConspectusHierarchical helicates are formed by noncovalent connection of two or more monomeric metal complex units, e.g., by bridging metal cations. A unique kind of hierarchical helicate is obtained from 3-carbonyl substituted catechol ligands with titanium(IV) ions in the presence of lithium cations. This kind of supramolecular complex shows in solution a "monomer-dimer" equilibrium. There are different possibilities (solvent, countercation, substituents at carbonyl unit, etc.) to shift this equilibrium to either the monomer or the dimer side. Thus, the lithium-bridged catecholate-based hierarchical helicates resemble a molecular switch. In this Account, different aspects are discussed of how this unique behavior of the dimeric titanium catecholates can be used for application.Thorough investigation of the energetics of the monomer-dimer equilibrium leads to a deeper understanding of the thermodynamic and kinetic effects of the dimerization (or dissociation) process. In this context, even weak interaction of substituents in the periphery of the complexes can be observed. Hereby on the one hand, solvent effects have an important influence and can be easily evaluated. The thorough understanding of the behavior of the monomer-dimer equilibrium allows one to develop some novel applications. In this respect, the use of the hierarchical helicate-based switch as a platform for reaction control and catalysis is described. Decent enantioselectivities up to ee = 58% can be found in Diels-Alder reactions in the periphery of the dimers, while switching to the monomer as a reaction platform still allows the cycloaddition reaction but turns the selectivity off. Additionally, it is described that catalytically important units can be introduced and hydrogenation reactions as well as Michael-type reactions are catalyzed at the helicates.Covalent connection of two catechol ester units leads to classical helicates. Depending on the alkaline metal cation, those can be switched from a compressed to an expanded form or vice versa. Hereby the monomer-dimer equilibrium is transformed into a structural switch. The switching process can be initiated by removal or addition of lithium cations (e.g., by addition of [2.1.1]cryptand). Alternative switching possibilities are based in the case of glycol bridged helicates on cation translocation isomerism and with thioester derivatives it occurs spontaneously in DMSO. Introduction of chiral tethers results in a three state switch allowing expansion/compression as well as switching of the helicity.
    Language English
    Publishing date 2023-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1483291-4
    ISSN 1520-4898 ; 0001-4842
    ISSN (online) 1520-4898
    ISSN 0001-4842
    DOI 10.1021/acs.accounts.3c00525
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Vergleich von Knochenmark und peripherem Blut als Stammzellquelle für die allogene hämatopoetische Stammzelltransplantation bei hämatologischen Erkrankungen

    Albrecht, Melanie

    eine systematische Übersicht und Meta-Analyse

    2017  

    Author's details vorgelegt von Melanie Albrecht
    Language German ; English
    Size 83 Blätter, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2017
    Note Enthält Sonderabdruck aus Zeitschrift in englischer Sprache
    HBZ-ID HT019401903
    Database Catalogue ZB MED Medicine, Health

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  4. Book: KTQ-Manual, KTQ-Katalog ab 2009 Krankenhaus

    Albrecht, Matthias

    2012  

    Institution KTQ GmbH
    Author's details [KTQ, Kooperation für Transparenz und Qualität im Gesundheitswesen. Red.-Team: Matthias Albrecht ...]
    Keywords Krankenhaus ; Qualitätssicherung ; Zertifizierung
    Subject Zertifizierungsverfahren ; Zertifizierungspolitik ; Zertifizieren ; Beschaffenheitssicherung ; Unternehmen ; Klinik ; Klinikum ; Krankenanstalt ; Krankenhauswesen ; Spital
    Subject code 362.110684
    Language German
    Size 225 S., 30 cm, 760 g
    Edition Version 2, 2., überarb. Aufl.
    Publisher Grimm
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    Accompanying material Übersicht "Aufbau des Kataloges: Krankenhaus" (4 S.)
    Old title 1.Aufl. u.d.T. KTQ-Manual und KTQ-Katalog ab 2009 Krankenhaus
    HBZ-ID HT017486684
    ISBN 978-3-940286-26-0 ; 3-940286-26-5
    Database Catalogue ZB MED Medicine, Health

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  5. Article: ETSC (evtl. Townsend oder Alonso) Neuerungen in den Begutachtungsleitlinien zur Kraftfahreignung

    Albrecht, M.

    Blutalkohol

    2021  Volume 58, Issue Suppl. 1, Page(s) 15

    Language German
    Document type Article
    ZDB-ID 213649-1
    ISSN 0006-5250
    Database Current Contents Medicine

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  6. Article: Den Alarm abschalten - Alarmine und andere epitheliale Mediatoren der allergischen Entzündung als Zielstrukturen von Biologika. CME-Fortbildung. Turning off the alarm - Targeting alarmins and other epithelial mediators of allergic inflammation with biologies

    Albrecht, M.

    Allergologie

    2021  Volume 44, Issue 3, Page(s) 183

    Language German
    Document type Article
    ZDB-ID 547065-1
    ISSN 0344-5062
    Database Current Contents Medicine

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  7. Article ; Online: Turning off the alarm - Targeting alarmins and other epithelial mediators of allergic inflammation with biologics.

    Albrecht, Melanie

    Allergologie select

    2021  Volume 5, Page(s) 82–88

    Abstract: Besides the major players IL-4, IL-13, IL-5, and IgE as targets for biologics, other mediators have been identified that are secreted by epithelial cells and act upstream in the cascade of allergic inflammation. Such are the alarmin IL-33 as well as TSLP ...

    Abstract Besides the major players IL-4, IL-13, IL-5, and IgE as targets for biologics, other mediators have been identified that are secreted by epithelial cells and act upstream in the cascade of allergic inflammation. Such are the alarmin IL-33 as well as TSLP and IL-5. The role of each cytokine in sensitization and effector phase of allergic inflammation and how development of biologics is ongoing in order to inhibit this pathomechanism will be described in the following article.
    Language English
    Publishing date 2021-02-09
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2893503-2
    ISSN 2512-8957 ; 2512-8957
    ISSN (online) 2512-8957
    ISSN 2512-8957
    DOI 10.5414/ALX02194E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: From C-H to C-N Bonds: Three Challenges, Three Catalysts, Three Solutions.

    Stroek, Wowa / Albrecht, Martin

    Chimia

    2024  Volume 78, Issue 4, Page(s) 205–208

    Abstract: N-heterocycles are key building blocks for many pharmaceutical products. An efficient and sustainable method for the synthesis of this class of compounds consists of the recently established intramolecular C-H amination reaction. Development of new iron- ... ...

    Abstract N-heterocycles are key building blocks for many pharmaceutical products. An efficient and sustainable method for the synthesis of this class of compounds consists of the recently established intramolecular C-H amination reaction. Development of new iron-based catalysts for this transformation is of paramount importance. Herein, three major challenges in this field are addressed: the accessibility of the catalyst, the lack of mechanisticunderstanding, and the limited activity and robustness of the catalyst. These challenges are tackled by threedifferent catalysts. The first catalyst is the commercially available FeI2, that shows good activities, but is limitedto substrates with activated C-H bonds. The Fe(HMDS)2 catalyst is used to perfom in-depth mechanistic studies, revealing key intermediates of the C-H amination reaction. The third catalyst, featuring mesoionic carbene ligands, displays unprecedented activities and aminates various C-H bonds.
    Language English
    Publishing date 2024-04-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1516-7
    ISSN 0009-4293
    ISSN 0009-4293
    DOI 10.2533/chimia.2024.205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Taschenbuch Histologie

    Albrecht, Martin / Wennemuth, Gunther

    2017  

    Author's details Gunther Wennemuth (Hrsg.) ; mit Beiträgen von: M. Albrecht [und 10 anderen]
    Keywords Histologie
    Subject Gewebelehre ; Mikroskopische Anatomie ; Mikroanatomie
    Language German
    Size XVI, 352 Seiten, Illustrationen, Diagramme, 21 cm x 13.5 cm
    Edition 2. Auflage
    Publisher Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist Taschenatlas Histologie
    HBZ-ID HT019419359
    ISBN 978-3-437-41978-2 ; 3-437-41978-1 ; 9783437180026 ; 3437180029
    Database Catalogue ZB MED Medicine, Health

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  10. Book ; Audio / Video ; Thesis: Rekombinante modifizierte Vaccinia-Viren Ankara (MVA) als neuartige Vakzinen zur spezifischen Immuntherapie (SIT) von schweren Formen der Lebensmittelallergie

    Albrecht, Melanie

    2009  

    Author's details von Melanie Albrecht
    Subject code 615.3
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2009
    Accompanying material Beil. ([1] Bl.)
    HBZ-ID HT016328934
    Database Catalogue ZB MED Medicine, Health

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