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  1. Article ; Online: Occupational risks associated with chronic kidney disease of non-traditional origin (CKDnt) in Brazil: it is time to dig deeper into a neglected problem.

    Buralli, Rafael Junqueira / Albuquerque, Polianna L M Moreira / Santo, Cintia da Espiritu / Calice-Silva, Viviane / Nerbass, Fabiana Baggio

    Jornal brasileiro de nefrologia

    2024  Volume 46, Issue 3, Page(s) e20230123

    Abstract: In the past decades, an epidemic of chronic kidney disease (CKD) has been associated with environmental and occupational factors (heat stress from high workloads in hot temperatures and exposure to chemicals, such as pesticides and metals), which has ... ...

    Abstract In the past decades, an epidemic of chronic kidney disease (CKD) has been associated with environmental and occupational factors (heat stress from high workloads in hot temperatures and exposure to chemicals, such as pesticides and metals), which has been termed CKD of non-traditional origin (CKDnt). This descriptive review aims to present recent evidence about heat stress, pesticides, and metals as possible causes of CKDnt and provide an overview of the related Brazilian regulation, enforcement, and health surveillance strategies. Brazilian workers are commonly exposed to extreme heat conditions and other CKDnt risk factors, including increasing exposure to pesticides and metals. Furthermore, there is a lack of adequate regulation (and enforcement), public policies, and strategies to protect the kidney health of workers, considering the main risk factors. CKDnt is likely to be a significant cause of CKD in Brazil, since CKD's etiology is unknown in many patients and several conditions for its development are present in the country. Further epidemiological studies may be conducted to explore causal associations and estimate the impact of heat, pesticides, and metals on CKDnt in Brazil. Moreover, public policies should prioritize reducing workers´ exposure and promoting their health and safety.
    MeSH term(s) Humans ; Brazil/epidemiology ; Risk Factors ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/etiology ; Pesticides
    Chemical Substances Pesticides
    Language Portuguese
    Publishing date 2024-04-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2057873-8
    ISSN 2175-8239 ; 2175-8239
    ISSN (online) 2175-8239
    ISSN 2175-8239
    DOI 10.1590/2175-8239-JBN-2023-0123en
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Crosstalk of Inflammation and Coagulation in

    Cavalcante, Joeliton S / de Almeida, Denis Emanuel Garcia / Santos-Filho, Norival A / Sartim, Marco Aurélio / de Almeida Baldo, Amanda / Brasileiro, Lisele / Albuquerque, Polianna L / Oliveira, Sâmella S / Sachett, Jacqueline Almeida Gonçalves / Monteiro, Wuelton Marcelo / Ferreira, Rui Seabra

    International journal of molecular sciences

    2023  Volume 24, Issue 14

    Abstract: Snakebite envenoming represents a major health problem in tropical and subtropical countries. Considering the elevated number of accidents and high morbidity and mortality rates, the World Health Organization reclassified this disease to category A of ... ...

    Abstract Snakebite envenoming represents a major health problem in tropical and subtropical countries. Considering the elevated number of accidents and high morbidity and mortality rates, the World Health Organization reclassified this disease to category A of neglected diseases. In Latin America,
    MeSH term(s) Humans ; Animals ; Snake Bites/complications ; Bothrops ; Blood Coagulation ; Inflammation/complications ; Signal Transduction
    Language English
    Publishing date 2023-07-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241411508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute kidney injury caused by Crotalus and Bothrops snake venom: a review of epidemiology, clinical manifestations and treatment.

    Albuquerque, Polianna L M M / Jacinto, Camilla N / Silva Junior, Geraldo B / Lima, Juliana B / Veras, Maria do Socorro B / Daher, Elizabeth F

    Revista do Instituto de Medicina Tropical de Sao Paulo

    2013  Volume 55, Issue 5, Page(s) 295–301

    Abstract: Ophidic accidents are an important public health problem due to their incidence, morbidity and mortality. An increasing number of cases have been registered in Brazil in the last few years. Several studies point to the importance of knowing the clinical ... ...

    Abstract Ophidic accidents are an important public health problem due to their incidence, morbidity and mortality. An increasing number of cases have been registered in Brazil in the last few years. Several studies point to the importance of knowing the clinical complications and adequate approach in these accidents. However, knowledge about the risk factors is not enough and there are an increasing number of deaths due to these accidents in Brazil. In this context, acute kidney injury (AKI) appears as one of the main causes of death and consequences for these victims, which are mainly young males working in rural areas. Snakes of the Bothrops and Crotalus genera are the main responsible for renal involvement in ophidic accidents in South America. The present study is a literature review of AKI caused by Bothrops and Crotalus snake venom regarding diverse characteristics, emphasizing the most appropriate therapeutic approach for these cases. Recent studies have been carried out searching for complementary therapies for the treatment of ophidic accidents, including the use of lipoic acid, simvastatin and allopurinol. Some plants, such as Apocynaceae, Lamiaceae and Rubiaceae seem to have a beneficial role in the treatment of this type of envenomation. Future studies will certainly find new therapeutic measures for ophidic accidents.
    MeSH term(s) Acute Kidney Injury/chemically induced ; Acute Kidney Injury/drug therapy ; Acute Kidney Injury/mortality ; Animals ; Bothrops ; Brazil/epidemiology ; Crotalid Venoms/poisoning ; Crotalus ; Humans ; Severity of Illness Index ; Snake Bites/complications ; Snake Bites/epidemiology
    Chemical Substances Crotalid Venoms
    Language English
    Publishing date 2013-09-15
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 128928-7
    ISSN 1678-9946 ; 0036-4665
    ISSN (online) 1678-9946
    ISSN 0036-4665
    DOI 10.1590/S0036-46652013000500001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 292: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Dengue and aplastic anemia--a rare association.

    Albuquerque, Polianna L M M / Silva Júnior, Geraldo B / Diógenes, Saulo S / Silva, Herivaldo F

    Travel medicine and infectious disease

    2009  Volume 7, Issue 2, Page(s) 118–120

    Abstract: Aplastic anemia is a medullary insufficiency secondary to the complete or partial disappearance of hematopoietic tissue without abnormal cellular proliferation. This is a rare complication of infections, such as dengue hemorrhagic fever. A 15-year-old ... ...

    Abstract Aplastic anemia is a medullary insufficiency secondary to the complete or partial disappearance of hematopoietic tissue without abnormal cellular proliferation. This is a rare complication of infections, such as dengue hemorrhagic fever. A 15-year-old girl was admitted with anemia, bleeding from the gums, petechiae and fever. Laboratory tests at the time of admission showed: Hemoglobin 4.8 g/dl; Hematocrit 13.4%; white blood count 2240/microl and platelets 11,500/microl. Dengue virus IgM antibodies were found. A bone marrow aspirate and biopsy showed severe aplastic anemia. Treatment with intravenous immunoglobulin and methylprednisolone was started. The patient had a favorable outcome. She was then given long-term treatment with cyclosporin. She is now in remission, without any symptoms. Dengue can induce aplastic anemia through direct bone marrow invasion. This is a rare complication which must be identified early. Immunosuppressive therapy can induce complete remission.
    MeSH term(s) Adolescent ; Anemia, Aplastic/diagnosis ; Anemia, Aplastic/drug therapy ; Anemia, Aplastic/etiology ; Anti-Inflammatory Agents/therapeutic use ; Brazil ; Dengue/complications ; Dengue/diagnosis ; Dengue/immunology ; Dengue Virus/isolation & purification ; Female ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/therapeutic use ; Methylprednisolone/therapeutic use ; Remission Induction
    Chemical Substances Anti-Inflammatory Agents ; Immunoglobulins, Intravenous ; Immunologic Factors ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2009-03
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2009.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6236: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Acute kidney injury after snakebite accident treated in a Brazilian tertiary care centre.

    Albuquerque, Polianna L M M / Silva, Geraldo B / Jacinto, Camilla N / Lima, Julianna B / Lima, Caroline B / Amaral, Yago S / Veras, Maria do Socorro B / Mota, Rosa M S / Daher, Elizabeth F

    Nephrology (Carlton, Vic.)

    2014  Volume 19, Issue 12, Page(s) 764–770

    Abstract: Aim: Acute kidney injury (AKI) is one of the main causes of morbidity and mortality in cases of envenomation by venomous snakes. The present study was carried out to investigate the clinical and laboratory manifestations in accidents with venomous ... ...

    Abstract Aim: Acute kidney injury (AKI) is one of the main causes of morbidity and mortality in cases of envenomation by venomous snakes. The present study was carried out to investigate the clinical and laboratory manifestations in accidents with venomous snakes and the risk factors associated with AKI in these accidents.
    Methods: A retrospective study was carried out with patients victims of snakebite admitted to a reference centre. AKI was defined according to the RIFLE and AKIN criteria.
    Results: A total of 276 patients were included, of which 230 (83.7%) were males. AKI was observed in 42 cases (15.2%). The mean genus involved in the accidents was Bothrops (82.2%). Mean age of patients with AKI was higher than in patients without AKI (43 ± 20 vs. 34 ± 21 years, P = 0.015). The time elapsed between the accident and medical care was higher in the AKI group (25 ± 28 vs. 14 ± 16h, P = 0.034), as well as the time elapsed between the accident and the administration of antivenom (30.7 ± 27 vs. 15 ± 16 h, P = 0.01). Haemodialysis was required in 30% of cases and complete renal function recovery was observed in 54.8% of cases at hospital discharge. There were four deaths, none of which had AKI. Factors associated with AKI were haemorrhagic abnormalities (P = 0.036, OR = 6.718, 95% CI: 1.067-25.661) and longer length of hospital stay (P = 0.004, OR = 1.69, 95% CI 1.165-2.088).
    Conclusion: Acute kidney injury is an important complication of snakebite accidents, showing low mortality, but high morbidity, which can lead to partial renal function recovery.
    MeSH term(s) Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Acute Kidney Injury/physiopathology ; Acute Kidney Injury/therapy ; Adolescent ; Adult ; Antivenins/therapeutic use ; Brazil ; Chi-Square Distribution ; Female ; Humans ; Kidney/physiopathology ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; Recovery of Function ; Renal Dialysis ; Retrospective Studies ; Risk Factors ; Snake Bites/complications ; Snake Bites/mortality ; Snake Bites/therapy ; Snake Venoms ; Tertiary Care Centers ; Time Factors ; Time-to-Treatment ; Treatment Outcome ; Young Adult
    Chemical Substances Antivenins ; Snake Venoms
    Language English
    Publishing date 2014-12
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1303661-0
    ISSN 1440-1797 ; 1320-5358
    ISSN (online) 1440-1797
    ISSN 1320-5358
    DOI 10.1111/nep.12327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4822: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Epidemiological profile of snakebite accidents in a metropolitan area of northeast Brazil.

    Albuquerque, Polianna L M M / Silva Junior, Geraldo B / Jacinto, Camilla N / Lima, Caroline B / Lima, Juliana B / Veras, Maria do Socorro B / Daher, Elizabeth F

    Revista do Instituto de Medicina Tropical de Sao Paulo

    2013  Volume 55, Issue 5, Page(s) 347–351

    Abstract: The aim of this study was to describe the epidemiological profile of snakebite accidents reported by the toxicological assistance center in Fortaleza, Ceará, Brazil. Database information on snakebite accidents was analyzed regarding the period from ... ...

    Abstract The aim of this study was to describe the epidemiological profile of snakebite accidents reported by the toxicological assistance center in Fortaleza, Ceará, Brazil. Database information on snakebite accidents was analyzed regarding the period from January 2003 to December 2011. A total of 1063 cases were found. The accidents occurred during the rainy months (March, April and May), in urban areas (52.3%), affecting individuals younger than 50 years and predominantly among males (70.7%). The lower limbs were the most frequently affected body area (33.7%). Most accidents involved non-venomous snakes (76.1%). The genus Bothrops was the main one involved in venomous accidents (83%). It is expected that this study can be used as the substrate to improve healthcare surveillance and implementing better measures for the treatment of this population.
    MeSH term(s) Adolescent ; Adult ; Aged ; Animals ; Bothrops ; Brazil/epidemiology ; Child ; Child, Preschool ; Humans ; Infant ; Male ; Middle Aged ; Prevalence ; Retrospective Studies ; Rural Population ; Severity of Illness Index ; Snake Bites/epidemiology ; Urban Population ; Young Adult
    Language English
    Publishing date 2013-09-15
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 128928-7
    ISSN 1678-9946 ; 0036-4665
    ISSN (online) 1678-9946
    ISSN 0036-4665
    DOI 10.1590/S0036-46652013000500009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 292: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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