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  1. Article ; Online: Trade your open tickets for interoperability.

    Aldrich, Kelly

    Nursing management

    2017  Volume 48, Issue 10, Page(s) 25–26

    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605889-9
    ISSN 1538-8670 ; 0744-6314
    ISSN (online) 1538-8670
    ISSN 0744-6314
    DOI 10.1097/01.NUMA.0000524822.79652.5b
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  2. Article ; Online: Partner with IT to reduce frustration, improve patient care.

    Aldrich, Kelly

    Nursing

    2017  Volume 47, Issue 12, Page(s) 68–69

    MeSH term(s) Attitude of Health Personnel ; Frustration ; Humans ; Information Technology ; Nurse's Role ; Nurses/psychology ; Patient Care/standards
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197895-0
    ISSN 1538-8689 ; 0360-4039
    ISSN (online) 1538-8689
    ISSN 0360-4039
    DOI 10.1097/01.NURSE.0000526895.15251.02
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  3. Article ; Online: Surgical data recording in the operating room: a systematic review of modalities and metrics.

    Levin, M / McKechnie, T / Kruse, C C / Aldrich, K / Grantcharov, T P / Langerman, A

    The British journal of surgery

    2021  Volume 108, Issue 6, Page(s) 613–621

    Abstract: Introduction: Operating room recording, via video, audio and sensor-based recordings, is increasingly common. Yet, surgical data science is a new field without clear guidelines. The purpose of this study is to examine existing published studies of ... ...

    Abstract Introduction: Operating room recording, via video, audio and sensor-based recordings, is increasingly common. Yet, surgical data science is a new field without clear guidelines. The purpose of this study is to examine existing published studies of surgical recording modalities to determine which are available for use in the operating room, as a first step towards developing unified standards for this field.
    Methods: Medline, EMBASE, CENTRAL and PubMed databases were systematically searched for articles describing modalities of data collection in the operating room. Search terms included 'video-audio media', 'bio-sensing techniques', 'sound', 'movement', 'operating rooms' and others. Title, abstract and full-text screening were completed to identify relevant articles. Descriptive statistical analysis was performed for included studies.
    Results: From 3756 citations, 91 studies met inclusion criteria. These studies described 10 unique data-collection modalities for 17 different purposes in the operating room. Data modalities included video, audio, kinematic and eye-tracking among others. Data-collection purposes described included surgical trainee assessment, surgical error, surgical team communication and operating room efficiency.
    Conclusion: Effective data collection and utilization in the operating room are imperative for the provision of superior surgical care. The future operating room landscape undoubtedly includes multiple modalities of data collection for a plethora of purposes. This review acts as a foundation for employing operating room data in a way that leads to meaningful benefit for patient care.
    MeSH term(s) Data Collection/instrumentation ; Data Collection/methods ; Humans ; Operating Rooms/statistics & numerical data ; Surgical Procedures, Operative/methods ; Surgical Procedures, Operative/statistics & numerical data ; Tape Recording ; Video Recording
    Language English
    Publishing date 2021-06-22
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab016
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  4. Article ; Online: Letter to the editor regarding: Chan, G. K., Cummins, M. R., Taylor, C. S., Rambur, B., Auerbach, D. I., Meadows-Oliver, M., ... & Pittman, P. P. (2023). An overview and policy implications of national nurse identifier systems: A call for unity and integration. Nursing Outlook, 101892.

    Kulhanek, Brenda / Carroll, Whende / Sensmeier, Joyce / Rajwany, Nur / Bensinger, Dana / Aldrich, Kelly / Alexander, Susan

    Nursing outlook

    2023  Volume 71, Issue 3, Page(s) 101980

    MeSH term(s) Humans ; Policy ; Nursing
    Language English
    Publishing date 2023-04-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 300568-9
    ISSN 1528-3968 ; 0029-6554
    ISSN (online) 1528-3968
    ISSN 0029-6554
    DOI 10.1016/j.outlook.2023.101980
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  5. Article ; Online: Pathways of calcium regulation, electron transport, and mitochondrial protein translation are molecular signatures of susceptibility to recurrent exertional rhabdomyolysis in Thoroughbred racehorses.

    Aldrich, Kennedy / Velez-Irizarry, Deborah / Fenger, Clara / Schott, Melissa / Valberg, Stephanie J

    PloS one

    2021  Volume 16, Issue 2, Page(s) e0244556

    Abstract: Recurrent exertional rhabdomyolysis (RER) is a chronic muscle disorder of unknown etiology in racehorses. A potential role of intramuscular calcium (Ca2+) dysregulation in RER has led to the use of dantrolene to prevent episodes of rhabdomyolysis. We ... ...

    Abstract Recurrent exertional rhabdomyolysis (RER) is a chronic muscle disorder of unknown etiology in racehorses. A potential role of intramuscular calcium (Ca2+) dysregulation in RER has led to the use of dantrolene to prevent episodes of rhabdomyolysis. We examined differentially expressed proteins (DEP) and gene transcripts (DEG) in gluteal muscle of Thoroughbred race-trained mares after exercise among three groups of 5 horses each; 1) horses susceptible to, but not currently experiencing rhabdomyolysis, 2) healthy horses with no history of RER (control), 3) RER-susceptible horses treated with dantrolene pre-exercise (RER-D). Tandem mass tag LC/MS/MS quantitative proteomics and RNA-seq analysis (FDR <0.05) was followed by gene ontology (GO) and semantic similarity of enrichment terms. Of the 375 proteins expressed, 125 were DEP in RER-susceptible versus control, with 52 ↑DEP mainly involving Ca2+ regulation (N = 11) (e.g. RYR1, calmodulin, calsequestrin, calpain), protein degradation (N = 6), antioxidants (N = 4), plasma membranes (N = 3), glyco(geno)lysis (N = 3) and 21 DEP being blood-borne. ↓DEP (N = 73) were largely mitochondrial (N = 45) impacting the electron transport system (28), enzymes (6), heat shock proteins (4), and contractile proteins (12) including Ca2+ binding proteins. There were 812 DEG in RER-susceptible versus control involving the electron transfer system, the mitochondrial transcription/translational response and notably the pro-apoptotic Ca2+-activated mitochondrial membrane transition pore (SLC25A27, BAX, ATP5 subunits). Upregulated mitochondrial DEG frequently had downregulation of their encoded DEP with semantic similarities highlighting signaling mechanisms regulating mitochondrial protein translation. RER-susceptible horses treated with dantrolene, which slows sarcoplasmic reticulum Ca2+ release, showed no DEG compared to control horses. We conclude that RER-susceptibility is associated with alterations in proteins, genes and pathways impacting myoplasmic Ca2+ regulation, the mitochondrion and protein degradation with opposing effects on mitochondrial transcriptional/translational responses and mitochondrial protein content. RER could potentially arise from excessive sarcoplasmic reticulum Ca2+ release and subsequent mitochondrial buffering of excessive myoplasmic Ca2+.
    MeSH term(s) Animals ; Calcium/metabolism ; Dantrolene/pharmacology ; Disease Susceptibility/metabolism ; Electron Transport/physiology ; Female ; Genetic Predisposition to Disease/genetics ; Horse Diseases/metabolism ; Horses/metabolism ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Muscle, Skeletal/metabolism ; Physical Exertion ; Rhabdomyolysis/metabolism ; Rhabdomyolysis/physiopathology ; Tandem Mass Spectrometry/methods
    Chemical Substances Mitochondrial Proteins ; Dantrolene (F64QU97QCR) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0244556
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  6. Article ; Online: Crohn disease: Identification, diagnosis, and clinical management.

    Snyder, Elizabeth F / Davis, Stephanie / Aldrich, Kristina / Veerabagu, Manjakkollai / Larussa, Tiziana / Abenavoli, Ludovico / Boccuto, Luigi

    The Nurse practitioner

    2021  Volume 46, Issue 12, Page(s) 22–30

    Abstract: Abstract: Crohn disease is an inflammatory bowel disorder affecting children and adults. With its increasing prevalence, healthcare providers need adequate resources to assist with diagnosis and management. This article discusses early diagnosis, ... ...

    Abstract Abstract: Crohn disease is an inflammatory bowel disorder affecting children and adults. With its increasing prevalence, healthcare providers need adequate resources to assist with diagnosis and management. This article discusses early diagnosis, disease severity and classification, familial predisposition and genomics, and clinical management in the primary care setting.
    MeSH term(s) Adult ; Child ; Crohn Disease/diagnosis ; Crohn Disease/epidemiology ; Diagnosis, Differential ; Humans ; Inflammatory Bowel Diseases/diagnosis ; Inflammatory Bowel Diseases/epidemiology ; Prevalence ; Severity of Illness Index
    Language English
    Publishing date 2021-11-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604085-8
    ISSN 1538-8662 ; 0361-1817
    ISSN (online) 1538-8662
    ISSN 0361-1817
    DOI 10.1097/01.NPR.0000798212.61425.4f
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  7. Article ; Online: Lessons Learned from the Development and Demonstration of a PPE Inventory Monitoring System for US Hospitals.

    Haas, Emily J / Casey, Megan L / Furek, Alexa / Aldrich, Kelly / Ragsdale, Tommy / Crosswy, Spencer / Moore, Susan M

    Health security

    2021  Volume 19, Issue 6, Page(s) 582–591

    Abstract: An international system should be established to support personal protective equipment (PPE) inventory monitoring, particularly within the healthcare industry. In this article, the authors discuss the development and 15-week deployment of a proof-of- ... ...

    Abstract An international system should be established to support personal protective equipment (PPE) inventory monitoring, particularly within the healthcare industry. In this article, the authors discuss the development and 15-week deployment of a proof-of-concept prototype that included the use of a Healthcare Trust Data Platform to secure and transmit PPE-related data. Seventy-eight hospitals participated, including 66 large hospital systems, 11 medium-sized hospital systems, and a single hospital. Hospitals reported near-daily inventory information for N95 respirators, surgical masks, and face shields, ultimately providing 159 different PPE model numbers. Researchers cross-checked the data to ensure the PPE could be accurately identified. In cases where the model number was inaccurately reported, researchers corrected the numbers whenever possible. Of the PPE model numbers reported, 74.2% were verified-60.5% of N95 respirators, 40.0% of face shields, and 84.0% of surgical masks. The authors discuss the need to standardize how PPE is reported, possible aspects of a PPE data standard, and standards groups who may assist with this effort. Having such PPE data standards would enable better communication across hospital systems and assist in emergency preparedness efforts during pandemics or natural disasters.
    MeSH term(s) COVID-19 ; Hospitals ; Humans ; Masks ; Pandemics ; Personal Protective Equipment
    Language English
    Publishing date 2021-11-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2823049-8
    ISSN 2326-5108 ; 2326-5094
    ISSN (online) 2326-5108
    ISSN 2326-5094
    DOI 10.1089/hs.2021.0098
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  8. Article ; Online: Neighborhood deprivation index is associated with weight status among long-term survivors of childhood acute lymphoblastic leukemia.

    Oluyomi, Abiodun / Aldrich, K Danielle / Foster, Kayla L / Badr, Hoda / Kamdar, Kala Y / Scheurer, Michael E / Lupo, Philip J / Brown, Austin L

    Journal of cancer survivorship : research and practice

    2020  Volume 15, Issue 5, Page(s) 767–775

    Abstract: Purpose: Area deprivation index (ADI), a measure of neighborhood socioeconomic disadvantage, has been linked to metabolic outcomes in the general population but has received limited attention in survivors of childhood acute lymphoblastic leukemia (ALL), ...

    Abstract Purpose: Area deprivation index (ADI), a measure of neighborhood socioeconomic disadvantage, has been linked to metabolic outcomes in the general population but has received limited attention in survivors of childhood acute lymphoblastic leukemia (ALL), a population with high rates of overweight and obesity.
    Methods: We retrospectively reviewed heights and weights of ≥ 5 year survivors of pediatric ALL (diagnosed 1990-2013). Residential addresses were geocoded using ArcGIS to assign quartiles of ADI, a composite of 17 measures of poverty, housing, employment, and education, with higher quartiles reflecting greater deprivation. Odds ratios (OR) and 95% confidence intervals (CI) for the association between ADI quartiles and overweight/obesity or obesity alone were calculated with logistic regression.
    Results: On average, participants (n = 454, 50.4% male, 45.2% Hispanic) were age 5.5 years at diagnosis and 17.4 years at follow-up. At follow-up, 26.4% were overweight and 24.4% obese. Compared to the lowest ADI quartile, survivors in the highest quartile were more likely to be overweight/obese at follow-up (OR = 2.33, 95% CI: 1.23-4.44) after adjusting for race/ethnicity, sex, age at diagnosis, and age at follow-up. The highest ADI quartile remained significantly associated with obesity (OR = 5.28, 95% CI: 1.79-15.54) after accounting for weight status at diagnosis.
    Conclusions: This study provides novel insights into possible social determinants of health inequalities among survivors of childhood ALL by reporting a significant association between neighborhood deprivation and overweight/obesity.
    Implications for cancer survivors: Survivors of childhood ALL residing in neighborhood with greater socioeconomic disadvantage may be at increased risk of overweight and obesity and candidates for targeted interventions.
    MeSH term(s) Child ; Child, Preschool ; Female ; Humans ; Male ; Overweight/epidemiology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/epidemiology ; Residence Characteristics ; Retrospective Studies ; Survivors
    Language English
    Publishing date 2020-11-23
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2388888-X
    ISSN 1932-2267 ; 1932-2259
    ISSN (online) 1932-2267
    ISSN 1932-2259
    DOI 10.1007/s11764-020-00968-7
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  9. Article ; Online: Overcoming barriers to electronic medical record (EMR) implementation in the US healthcare system: A comparative study.

    Kumar, Sameer / Aldrich, Krista

    Health informatics journal

    2010  Volume 16, Issue 4, Page(s) 306–318

    Abstract: An EMR system implementation would significantly reduce clinician workload and medical errors while saving the US healthcare system major expense. Yet, compared to other developed nations, the US lags behind. This article examines EMR system efforts, ... ...

    Abstract An EMR system implementation would significantly reduce clinician workload and medical errors while saving the US healthcare system major expense. Yet, compared to other developed nations, the US lags behind. This article examines EMR system efforts, benefits, and barriers, as well as steps needed to move the US closer to a nationwide EMR system. The analysis includes a blueprint for implementation of EMR, industry comparisons to highlight the differences between successful and non-successful EMR ventures, references to costs and benefit information, and identification of root causes. 'Poka-yokes' (avoid (yokeru) mistakes (poka)) will be inserted to provide insight into how to systematically overcome challenges. Implementation will require upfront costs including patient privacy that must be addressed early in the development process. Government structure, incentives and mandates are required for nationwide EMR system in the US.
    MeSH term(s) Cost-Benefit Analysis ; Diffusion of Innovation ; Electronic Health Records/economics ; Electronic Health Records/utilization ; Organizational Innovation ; United States
    Language English
    Publishing date 2010-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2213115-2
    ISSN 1741-2811 ; 1460-4582
    ISSN (online) 1741-2811
    ISSN 1460-4582
    DOI 10.1177/1460458210380523
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  10. Article: Comparison of erythrocyte osmotic fragility among ectotherms and endotherms at three temperatures.

    Aldrich, K / Saunders, D K.

    Journal of thermal biology

    2001  Volume 26, Issue 3, Page(s) 179–182

    Abstract: 1. Comparison of erythrocyte osmotic fragility (EOF) between various ectotherms and endotherms was investigated at 5, 25, and 38 degrees C. 2. We hypothesized that ectotherms might possess erythrocytes whose osmotic fragility would be less affected by ... ...

    Abstract 1. Comparison of erythrocyte osmotic fragility (EOF) between various ectotherms and endotherms was investigated at 5, 25, and 38 degrees C. 2. We hypothesized that ectotherms might possess erythrocytes whose osmotic fragility would be less affected by temperature than those of endotherms. 3. Ectotherm erythrocytes were much more osmotically resistant than those of endotherms. 4. The EOF of ectotherms and endotherms showed similar responses to temperature. 5. It does not appear that the osmotic fragility of erythrocytes from ectotherms in this study are adapted to be less affected by temperature than those of endotherms. The highly osmotic resistant erythrocytes of ectotherms may alleviate the need for further adaptation for osmotic resistance.
    Language English
    Publishing date 2001-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1498364-3
    ISSN 1879-0992 ; 0306-4565
    ISSN (online) 1879-0992
    ISSN 0306-4565
    DOI 10.1016/s0306-4565(00)00040-1
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