LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: HRAS

    Rodríguez, Nelson A / Patel, Nihir / Dariolli, Rafael / Ng, Simon / Aleman, Angelika G / Gong, Jingqi Q X / Lin, Hung-Mo / Rodríguez, Matthew / Josowitz, Rebecca / Sol-Church, Katia / Gripp, Karen W / Lin, Xianming / Song, Soomin C / Fishman, Glenn I / Sobie, Eric A / Gelb, Bruce D

    Circulation. Arrhythmia and electrophysiology

    2024  Volume 17, Issue 4, Page(s) e012022

    Abstract: Background: Germline : Methods: HRAS: Results: ACMs harboring : Conclusions: CS-associated gain-of- ... ...

    Abstract Background: Germline
    Methods: HRAS
    Results: ACMs harboring
    Conclusions: CS-associated gain-of-function
    MeSH term(s) Humans ; Child, Preschool ; Myocytes, Cardiac/metabolism ; Calcium/metabolism ; Heart Atria/metabolism ; Tachycardia ; Calcium Channels/metabolism ; Induced Pluripotent Stem Cells/metabolism ; Action Potentials/physiology ; Cell Differentiation ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism
    Chemical Substances Calcium (SY7Q814VUP) ; Calcium Channels ; HRAS protein, human (EC 3.6.5.2) ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2426129-4
    ISSN 1941-3084 ; 1941-3149
    ISSN (online) 1941-3084
    ISSN 1941-3149
    DOI 10.1161/CIRCEP.123.012022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6667: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Activation of Nkx2.5 transcriptional program is required for adult myocardial repair.

    de Sena-Tomás, Carmen / Aleman, Angelika G / Ford, Caitlin / Varshney, Akriti / Yao, Di / Harrington, Jamie K / Saúde, Leonor / Ramialison, Mirana / Targoff, Kimara L

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 2970

    Abstract: The cardiac developmental network has been associated with myocardial regenerative potential. However, the embryonic signals triggered following injury have yet to be fully elucidated. Nkx2.5 is a key causative transcription factor associated with human ... ...

    Abstract The cardiac developmental network has been associated with myocardial regenerative potential. However, the embryonic signals triggered following injury have yet to be fully elucidated. Nkx2.5 is a key causative transcription factor associated with human congenital heart disease and one of the earliest markers of cardiac progenitors, thus it serves as a promising candidate. Here, we show that cardiac-specific RNA-sequencing studies reveal a disrupted embryonic transcriptional profile in the adult Nkx2.5 loss-of-function myocardium. nkx2.5
    MeSH term(s) Animals ; Heart Ventricles/metabolism ; Homeobox Protein Nkx-2.5/genetics ; Homeobox Protein Nkx-2.5/metabolism ; Myocardium/metabolism ; Myocytes, Cardiac/metabolism ; Transcription Factors/metabolism
    Chemical Substances Homeobox Protein Nkx-2.5 ; Transcription Factors
    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-30468-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top